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5 p, 178.9 KB |
Outcome of Second Allogeneic Hematopoietic Cell Transplantation after Relapse of Myeloid Malignancies following Allogeneic Hematopoietic Cell Transplantation : A Retrospective Cohort on Behalf of the Grupo Español de Trasplante Hematopoyetico
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Orti, Guillermo (Grupo Español de Trasplante Hematopoyetico) ;
Sanz, Jaime (Grupo Español de Trasplante Hematopoyetico) ;
Bermúdez, Arancha (Grupo Español de Trasplante Hematopoyetico) ;
Caballero, Dolores (Grupo Español de Trasplante Hematopoyetico) ;
Martinez, Carmen (Grupo Español de Trasplante Hematopoyetico) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Cabrera Marin, José R. (Grupo Español de Trasplante Hematopoyetico) ;
Espigado, Ildefonso (Grupo Español de Trasplante Hematopoyetico) ;
Solano, Carlos (Grupo Español de Trasplante Hematopoyetico) ;
Ferrà, Christelle (Grupo Español de Trasplante Hematopoyetico) ;
García-Noblejas, Ana (Grupo Español de Trasplante Hematopoyetico) ;
Jimenez, Santiago (Grupo Español de Trasplante Hematopoyetico) ;
Sampol, Antonia (Grupo Español de Trasplante Hematopoyetico) ;
Yañez, Lucrecia (Grupo Español de Trasplante Hematopoyetico) ;
García-Gutiérrez, Valentin (Grupo Español de Trasplante Hematopoyetico) ;
Pascual, Maria Jesus (Grupo Español de Trasplante Hematopoyetico) ;
Jurado, Manuel (Grupo Español de Trasplante Hematopoyetico) ;
Moraleda, José M. (Grupo Español de Trasplante Hematopoyetico) ;
Valcarcel, David (Grupo Español de Trasplante Hematopoyetico) ;
Sanz, Miguel A. (Grupo Español de Trasplante Hematopoyetico) ;
Carreras, Enric (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Duarte, Rafael F. (Grupo Español de Trasplante Hematopoyetico) ;
Universitat Autònoma de Barcelona
Allogeneic stem cell transplantation (allo-HCT) represents the most effective immunotherapy for acute myeloid leukemia (AML) and myeloid malignancies. However, disease relapse remains the most common cause of treatment failure. [...]
2016 -  10.1016/j.bbmt.2015.11.012
Biology of blood and marrow transplantation, Vol. 22 Núm. 3 (january 2016) , p. 584-588
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2.
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10 p, 786.4 KB |
Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation : An EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine
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Giannotti, Federica (Saint-Antoine Hospital) ;
Labopin, Myriam (Hôpital Saint-Antoine (Paris, França)) ;
Shouval, Roni (Chaim Sheba Medical Center (Israel)) ;
Sanz, Jaime (Instituto de Salud Carlos III) ;
Arcese, William (Rome Transplant Network tor Vergatä) ;
Angelucci, Emanuele (Ospedale Policlinico San Martino) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santarone, Stella (Ospedale Civile) ;
Benedetto, Bruno (S.S.C.V.D Trapianto di Cellule Staminali A.O.U Citta della Salute e della Scienza di Torino) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni XXIII) ;
Saccardi, Riccardo (Azienda Ospedaliera Universitaria Careggi) ;
Blaise, Didier (Institut Paoli Calmettes) ;
Carella, Michele Angelo (IRCCS) ;
Rocha, Vanderson (Universidade de São Paulo) ;
Baron, Frederic (University of Liege) ;
Mohty, Mohamad (Hospital Saint- Antoine) ;
Ruggeri, Annalisa (Ospedale Pediatrico Bambino Gesù (Roma, Itàlia)) ;
Nagler, Arnon (Tel-Aviv University) ;
Universitat Autònoma de Barcelona
Thiotepa-busulfan-fludarabine (TBF) is a widely used conditioning regimen in single umbilical cord blood transplantation (SUCBT). More recently, it was introduced in the setting of non-T cell depleted haploidentical stem cell transplantation (NTD-Haplo). [...]
2018 - 10.1186/s13045-018-0655-8
Journal of hematology & oncology, Vol. 11 Núm. 1 (30 2018) , p. 110
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3.
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7 p, 530.8 KB |
Reduced-Intensity versus Myeloablative Conditioning in Cord Blood Transplantation for Acute Myeloid Leukemia (40-60 years) across Highly Mismatched HLA Barriers-On Behalf of Eurocord and the Cellular Therapy & Immunobiology Working Party (CTIWP) of EBMT
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Sheth, Vipul (Fred Hutchison Cancer Research Centre) ;
Volt, Fernanda (Eurocord) ;
Sanz, Jaime (Hospital Universitari i Politècnic La Fe (València)) ;
Clement, Laurence (Haut-Lévêque) ;
Cornelissen, Jan (Erasmus MC-Daniel den Hoed Cancer Centre) ;
Blaise, Didier (Paoli Calmettes) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Michallet, Mauricette (Centre Leon Berard) ;
Saccardi, Riccardo (Careggi University Hospital (Florència, Itàlia)) ;
Rocha, Vanderson (Eurocord) ;
Gluckman, Eliane (Eurocord) ;
Chabannon, Christian (Institut Paoli-Calmettes) ;
Ruggeri, Annalisa (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Universitat Autònoma de Barcelona
The use of myeloablative conditioning (MAC) in umbilical cord blood transplantation (UCBT) has been associated with high nonrelapse mortality (NRM) in patients aged >40 years, especially those having a high HLA disparity, thus limiting wider applications. [...]
2020 - 10.1016/j.bbmt.2020.07.025
Biology of blood and marrow transplantation, Vol. 26 Núm. 11 (november 2020) , p. 2098-2104
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4.
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11 p, 340.8 KB |
Outcomes of subsequent neoplasms after umbilical cord blood transplantation in Europe
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Rafii, Hanadi (Centre Scientifique de Monaco) ;
Ruggeri, Annalisa (IRCCS San Raffaele Scientific Institute (Milan, Itàlia)) ;
Kenzey, Chantal (Centre Scientifique de Monaco) ;
Sanz, Jaime (Hospital Universitari i Politècnic La Fe (València)) ;
Peffault De La Tour, Régis (Assistance Publique-Hôpitaux de Paris) ;
Esquirol, Albert (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Michel, Gérard (Hopital pédiatrique de la Timone (Marseille, França)) ;
Chevallier, Patrice (Hospital Hotel Dieu (Nantes, França)) ;
Rubio, Marie-Thérèse (CHRU Nancy (Nancy, França)) ;
Cornelissen, Jan J. (Erasmus MC-Daniel den Hoed Cancer Centre) ;
Michallet, Mauricette (Centre Leon Berard) ;
Volt, Fernanda (Monacord, Centre Scientifique de Monaco) ;
Rivera-Franco, Monica M. (Centre Scientifique de Monaco) ;
Scigliuolo, Graziana Maria (Centre Scientifique de Monaco) ;
Cappelli, Barbara (Centre Scientifique de Monaco) ;
Rocha, Vanderson (São Paulo Medical School) ;
Gluckman, Eliane (Centre Scientifique de Monaco) ;
Universitat Autònoma de Barcelona
Subsequent neoplasms (SNs) compromise long-term survivors after hematopoietic cell transplantation. We performed a retrospective analysis of SNs in 10 358 recipients of umbilical cord blood transplantation (UCBT) from 1988 to 2018. [...]
2022 - 10.1182/bloodadvances.2022007941
Blood advances, Vol. 7 (november 2022) , p. 1976-1986
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5.
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15 p, 669.1 KB |
Exposure to valproic acid is associated with less pulmonary infiltrates and improvements in diverse clinical outcomes and laboratory parameters in patients hospitalized with COVID-19
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Collazos, Julio (Hospital de Galdakao. Servicio de Enfermedades Infecciosas) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Fernández-Araujo, Nerio (Hospital General Universitario Gregorio Marañón) ;
Asensi-Díaz, Elia (Hospital Universitario Fundación Jiménez Díaz) ;
Vilchez-Rueda, Helem (Hospital Universitario Son Espases. Enfermedades Infecciosas) ;
Lalueza, Antonio (Hospital Universitario 12 de Octubre (Madrid)) ;
Roy-Vallejo, Emilia (Hospital Universitario de La Princesa. Enfermedades Infecciosas) ;
Blanes, Rosa (Hospital Universitari i Politècnic La Fe (València)) ;
Raya-Cruz, Manuel (Hospital Son Llàtzer. Servicio de Medicina Interna) ;
Sanz-Cánovas, Jaime (Hospital Regional Universitario de Málaga) ;
Artero, Arturo (Hospital Universitari Doctor Peset (València)) ;
Ramos-Rincón, José-Manuel (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Dueñas-Gutiérrez, Carlos (Hospital Clínico Universitario de Valladolid. Unidad de Enfermedades Infecciosas) ;
Lamas-Ferreiro, José Luis (Hospital Ribera POVISA. Servicio de Medicina Interna) ;
Asensi, Víctor (Hospital Universitario Central de Asturias. Unidad de Enfermedades Infecciosas)
Background Valproic acid (VPA) has shown beneficial effects in vitro against SARS-CoV-2 infection, but no study has analyzed its efficacy in the clinical setting. Methods This multicenter, retrospective study included 165 adult patients receiving VPA at the time of admission to hospital, and 330 controls matched for sex, age and date of admission. [...]
2022 - 10.1371/journal.pone.0262777
PloS one, Vol. 17 Núm. 1 January (january 2022) , p. e0262777
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12 p, 927.8 KB |
Axicabtagene ciloleucel compared to tisagenlecleucel for the treatment of aggressive B-cell lymphoma
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Kwon, Mi (Hospital General Universitario Gregorio Marañón) ;
Iacoboni, Gloria (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Reguera-Ortega, Juan Luis (Instituto de Biomedicina de Sevilla) ;
Corral, Lucía López (Instituto de Investigación Biomédica de Salamanca) ;
Morales, Rafael Hernani (Hospital Clínic Universitari (València)) ;
Ortiz-Maldonado, Valentín (Hospital Clínic i Provincial de Barcelona) ;
Guerreiro, Manuel (Hospital Universitari i Politècnic La Fe (València)) ;
Caballero, Ana Carolina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Domínguez, María Luisa Guerra (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Pina, Jose Maria Sanchez (Hospital Universitario 12 de Octubre (Madrid)) ;
Mussetti, Alberto (Institut Català d'Oncologia) ;
Sancho, Juan-Manuel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bastos, Mariana (Hospital General Universitario Gregorio Marañón) ;
Catala, Eva (Vall d'Hebron Institut d'Oncologia) ;
Delgado, Javier (Instituto de Biomedicina de Sevilla) ;
Henriquez, Hugo Luzardo (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Sanz, Jaime (Hospital Universitari i Politècnic La Fe (València)) ;
Calbacho, Maria (Hospital Universitario 12 de Octubre (Madrid)) ;
Bailén, Rebeca (Hospital General Universitario Gregorio Marañón) ;
Carpio Segura, Cecilia del Carmen (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ribera Santasusana, Jose Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Sureda, Anna (Institut Català d'Oncologia) ;
Briones Meijide, Javier (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Hernandez-Boluda, Juan Carlos (Hospital Clínic Universitari (València)) ;
Cebrián, Nuria Martínez (Hospital Clínic i Provincial de Barcelona) ;
Martin, Jose Luis Diez (Universidad Complutense de Madrid) ;
Martín, Alejandro (Instituto de Investigación Biomédica de Salamanca) ;
Barba, Pere (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Axicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) are CD19-targeted chimeric antigen receptor (CAR) T cells approved for relapsed/refractory (R/R) large B-cell lymphoma (LBCL). We performed a retrospective study to evaluate safety and efficacy of axi-cel and tisa-cel outside the setting of a clinical trial. [...]
2022 - 10.3324/haematol.2022.280805
Haematologica, Vol. 108 (january 2023) , p. 110-121
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13 p, 1.0 MB |
Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia : A comparative study of the ALWP EBMT
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Sanz, Jaime (Centro de Investigación Biomédica en Red de Cáncer) ;
Galimard, J. E. (EBMT Paris Office. Hospital Saint Antoine) ;
Labopin, Myriam (Department of Hematology. Hopital Saint Antoine. Sorbonne University) ;
Afanasyev, B. (First State Pavlov Medical University of St. Petersburg. Raisa Gorbacheva Mem. Research Institute for Paediatric Oncology. Hematology. and Transplantation) ;
Angelucci, Emanuele (Department of Haematology. IRCCS Ospedale Policlinico San Martino) ;
Ciceri, Fabio (Haematology and BMT) ;
Blaise, Didier (Programme de Transplantation and Therapie Cellulaire. Centre de Recherche en Cancérologie de Marseille. Institut Paoli Calmettes) ;
Cornelissen, J. J. (Department of Hematology. Erasmus MC Cancer Institute. University Medical Center Rotterdam) ;
Meijer, E. (Department of Hematology (Br 250). VU University Medical Center) ;
Diez-Martin, J. L. (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Koc, Y. (Stem Cell Transplant Unit. Medical Park Hospitals) ;
Rovira Tarrats, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Castagna, L. (Transplantation Unit. Department of Oncology and Haematology. Istituto Clinico Humanitas) ;
Savani, B. N. (Vanderbilt University Medical Center) ;
Ruggeri, Annalisa (Ospedale Pediatrico Bambino Gesù (Roma, Itàlia)) ;
Nagler, Arnon (ALWP of the EBMT Office. Saint Antoine Hospital) ;
Mohty, Mohamad (Department of Hematology. Hopital Saint Antoine. Sorbonne University) ;
Universitat Autònoma de Barcelona
Background: The use of post-transplant cyclophosphamide (PTCy) is highly effective in preventing graft-versus-host disease (GVHD) in the haploidentical (Haplo) transplant setting and is being increasingly used in matched sibling (MSD) and matched unrelated (MUD) transplants. [...]
2020 - 10.1186/s13045-020-00882-6
Journal of hematology & oncology, Vol. 13 Núm. 1 (june 2020) , p. 46
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16 p, 971.1 KB |
Cost-Effectiveness of Posaconazole Tablets for Invasive Fungal Infections Prevention in Acute Myelogenous Leukemia or Myelodysplastic Syndrome Patients in Spain
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Cámara, Rafael (Hospital Universitario de la Princesa (Madrid)) ;
Gozalbo, Irmina (Outcomes10, Castellon, Spain) ;
Jurado, Manuel (Granada, Spain) ;
Sanz, Jaime (Valencia, Spain) ;
Aragón, Belén (Merck Sharp & Dome Corp, Madrid, Spain) ;
Grau, Santiago (Hospital del Mar (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Posaconazole is superior to fluconazole (FLU) and itraconazole (ITRA) in the prevention of invasive fungal diseases (IFDs) in neutropenic patients with acute myelogenous leukemia (AML) and myelodysplastic syndrome (MDS). [...]
2017 - 10.1007/s12325-017-0600-1
Advances in Therapy, Vol. 34 (august 2017) , p. 2104-2119
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