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7 p, 4.0 MB The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design / Lima Moura, Silio (Universitat Autònoma de Barcelona. Departament de Química) ; Pallarès-Rusiñol, Arnau (Universitat Autònoma de Barcelona. Departament de Química) ; Sappia, Luciano (Universitat Autònoma de Barcelona. Departament de Química) ; Martí, Mercè (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
This work addresses a biosensor combining the immunomagnetic separation and the electrochemical biosensing based on the intrinsic ALP activity of the exosomes. This approach explores for the first time two different types of biomarkers on exosomes, in a unique biosensing device combining two different biorecognition reaction: immunological and enzymatic. [...]
2022 - 10.1016/j.bios.2021.113826
Biosensors & bioelectronics, Vol. 198 (February 2022) , art. 113826  
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