Results overview: Found 6 records in 0.02 seconds.
Articles, 5 records found
Research literature, 1 records found
Articles 5 records found  
1.
11 p, 1.5 MB The frequency of defective genomes in Omicron differs from that of the Alpha, Beta and Delta variants / Campos, Carolina (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Colomer-Castell, Sergi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia-Cehic, D. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Gregori i Font, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Andrés, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Piñana, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González-Sánchez, Alejandra (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Borras Bermejo, Blanca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Parés-Badell, Oleguer (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Adombi, Caroline Melanie (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ibañez-Lligoña, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esperalba, Juliana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Codina, María Gema (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rando-Segura, Ariadna (Hospital Universitari Vall d'Hebron) ; Saubí, Narcis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteban Mur, Juan Ignacio (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez Frías, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pumarola Suñé, Tomàs (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Antón, Andrés (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Quer, Josep 1963- (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The SARS-CoV-2 Omicron variant emerged showing higher transmissibility and possibly higher resistance to current COVID-19 vaccines than other variants dominating the global pandemic. In March 2020 we performed a study in clinical samples, where we found that a portion of genomes in the SARS-CoV-2 viral population accumulated deletions immediately before the S1/S2 cleavage site (furin-like cleavage site, PRRAR/S) of the spike gene, generating a frameshift and appearance of a premature stop codon. [...]
2022 - 10.1038/s41598-022-24918-8
Scientific reports, Vol. 12 (december 2022)  
2.
920.0 KB Designing Chimeric Virus-like Particle-based Vaccines for Human Papillomavirus and HIV: Lessons Learned / Eto, Yoshiki (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Saubi, Narcis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Joseph, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Virus-like particles (VLPs) are a type of subunit vaccine which resembles viruses but do not contain any genetic material so that they are not infectious. VLPs maintain the same antigenic conformation to the original virus, and they could be a better vaccine candidate than live-attenuated and inactivated vaccines. [...]
2019 - 10.24875/AIDSRev.19000114
AIDS Reviews, Vol. 21 Núm. 4 (2019) , p. 218-232  
3.
17 p, 14.9 MB Expression of Chimeric HPV-HIV Protein L1P18 in Pichia pastoris; Purification and Characterization of the Virus-like Particles / Eto, Yoshiki (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Saubi, Narcis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Joseph-Munné, Joan (Hospital Universitari Vall d'Hebron)
Currently, three human papillomavirus (HPV) vaccines are already licensed and all of them are based on virus-like particles (VLPs) of HPV L1 capsid protein but not worldwide accessible. While about 38. [...]
2021 - 10.3390/pharmaceutics13111967
Pharmaceutics, Vol. 13, Issue 11 (November 2021) , art. 1967  
4.
19 p, 3.7 MB Recombinant BCG expressing HTI prime and recombinant ChAdOx1 boost is safe and elicits HIV-1-specific T-cell responses in BALB/c mice / Kilpeläinen, Athina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Saubi, Narcis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guitart, Núria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Olvera, Alex (Universitat de Vic - Universitat Central de Catalunya) ; Hanke, Tomáš (Kumamoto University. International Research Center of Medical Sciences (IRCMS)) ; Brander, Christian. (AELIX Therapeutics) ; Joseph, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Despite the availability of anti-retroviral therapy, HIV-1 infection remains a massive burden on healthcare systems. Bacillus Calmette-Guérin (BCG), the only licensed vaccine against tuberculosis, confers protection against meningitis and miliary tuberculosis in infants. [...]
2019 - 10.3390/vaccines7030078
Vaccines (Basel), Vol. 7 Núm. 3 (september 2019) , p. 78  
5.
10 p, 763.1 KB Engineering new mycobacterial vaccine design for HIV-TB pediatric vaccine vectored by lysine auxotroph of BCG / Saubi, Narcis (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Gea-Mallorquí, Ester (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Hurtado, Carmen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Sánchez-Úbeda, Sara (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Eto, Yoshiki (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Gatell, Josep M.. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Hanke, Tomáš (University of Oxford. Weatherall Institute of Molecular Medicine) ; Joseph, Joan (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
In this study, we have engineered a new mycobacterial vaccine design by using an antibiotic-free plasmid selection system. We assembled a novel Escherichia coli (E. coli)-mycobacterial shuttle plasmid p2auxo. [...]
2014 - 10.1038/mtm.2014.17
Molecular Therapy. Methods & Clinical Development, Vol. 1 (May 2014) , art. 14017  

Research literature 1 records found  
1.
123 p, 4.1 MB Scaling up recombinant BCG based HIV vaccine development. Lessons learned / Saubi, Narcis ; Joseph Munné, Joan, dir. ; Farrés, Jaume, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
El treball de recerca realitzat en aquesta Tesi Doctoral està dirigit a la millora del desenvolupament de la vacuna contra el VIH basada en BCG recombinant. La Tesi Doctoral inclou tres articles de recerca publicats en revistes "peer-reviewed" i una patent depositada a la Oficina Europea de Patents. [...]
The research work of this PhD thesis aims to scale up recombinant BCG based HIV vaccine development. Our main goal is to develop a mycobacterial vaccine design for HIV-TB pediatric vaccine. The PhD thesis includes three research papers published in peer-reviewed journals and one patent filed in the European patent office. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  

See also: similar author names
8 Saubi, Narcís
8 Saubí, Narcis
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