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25 p, 1.2 MB |
European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE) : Expert Consensus on the Diagnosis, Service Provision, and Care of People with ME/CFS in Europe
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Nacul, Luis (BC Women's Hospital) ;
Authier, François Jérôme (Faculty of Medicine Créteil-Paris Est) ;
Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin) ;
Lorusso, Lorenzo (Neurology and Stroke Unit-Neuroscience Department, Italy) ;
Helland, Ingrid Bergliot (Oslo University Hospital (Oslo, Noruega)) ;
Martin, Jose Alegre (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sirbu, Carmen Adella (Titu Maiorescu University) ;
Mengshoel, Anne Marit (University of Oslo) ;
Polo, Olli (Bragée ME/CFS Center) ;
Behrends, Uta (Technical University of Munich) ;
Nielsen, Henrik (Privat Hospitalet Danmark) ;
Grabowski, Patricia (in,Charite Medical School) ;
Sekulic, Slobodan (University of Novi Sad) ;
Sepulveda, Nuno (University of Lisbon) ;
Estévez-López, Fernando (Erasmus MC University Medical Center) ;
Zalewski, Paweł (Nicolaus Copernicus University in Torun) ;
Pheby, Derek (Buckinghamshire New University) ;
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sakkas, Giorgos K. (University of Thessaly) ;
Capelli, Enrica (University of Pavia) ;
Brundsdlund, Ivan (Odense University Hospital (Dinamarca)) ;
Cullinan, John (National University of Ireland Galway) ;
Krumina, Angelika (Riga Stradins University) ;
Bergquist, Jonas (Uppsala University) ;
Murovska, Modra (Riga Stradins University) ;
Vermuelen, Ruud C. W. (CFS/ME Medical Centre, The Netherlands) ;
Lacerda, Eliana (London School of Hygiene and Tropical Medicine) ;
Universitat Autònoma de Barcelona
Designed by a group of ME/CFS researchers and health professionals, the European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE) has received funding from the European Cooperation in Science and Technology (COST)-COST action 15111-from 2016 to 2020. [...]
2021 -  10.3390/medicina57050510
Medicina, Vol. 57 (may 2021)
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38 p, 310.7 KB |
The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome : analysis of high-throughput epigenetic and gene expression studies
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Malato, João (Universidade de Lisboa) ;
Sotzny, Franziska (Humboldt-Universität zu Berlin) ;
Bauer, Sandra (Charité - Universitätsmedizin Berlin) ;
Freitag, Helma (Charité - Universitätsmedizin Berlin) ;
Fonseca, André (Universidade do Algarve) ;
Grabowska, Anna D. (Medical University of Warsaw) ;
Graça, Luís (Universidade de Lisboa) ;
Cordeiro, Clara (Universidade do Algarve) ;
Nacul, Luís (British Columbia Women's Hospital and Health Centre (Canada)) ;
Lacerda, Eliana (London School of Hygiene & Tropical Medicine) ;
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin) ;
Westermeier, Francisco (Universidad Bernardo O'Higgins (Xile)) ;
Sepúlveda, Nuno (London School of Hygiene & Tropical Medicine) ;
Universitat Autònoma de Barcelona
Patients affected by Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) show specific epigenetic and gene expression signatures of the disease. However, it is unknown whether these signatures include abnormal levels of the human angiotensin-converting enzymes, ACE and ACE2, the latter being the main receptor described for the host-cell invasion by SARS-CoV-2. [...]
2021 - 10.1101/2021.03.23.21254175
medRxiv, april 2021
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7 p, 1.0 MB |
The European ME/CFS Biomarker Landscape project : an initiative of the European network EUROMENE
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Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin) ;
Freitag, Helma (Charité - Universitätsmedizin Berlin) ;
Blanco, Julià (Universitat de Vic) ;
Capelli, Enrica (University of Pavia) ;
Lacerda, Eliana (London School of Hygiene & Tropical Medicine) ;
Authier, Jerome (Paris Est-Creteil University) ;
Meeus, Mira (University of Antwerp) ;
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron) ;
Nora-Krukle, Zaiga (Riga Stradins University) ;
Oltra, Elisa (Centro de Investigación Príncipe Felipe (València)) ;
Strand, Elin Bolle (Copenhagen University Hospital Rigshospitalet) ;
Shikova, Evelina (National Center of Infectious and Parasitic Diseases) ;
Sekulic, Slobodan (Medical Faculty Novi Sad) ;
Murovska, Modra (Riga Stradins University) ;
Universitat Autònoma de Barcelona
Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a common and severe disease with a considerable social and economic impact. So far, the etiology is not known, and neither a diagnostic marker nor licensed treatments are available yet. [...]
2017 - 10.1186/s12967-017-1263-z
Journal of translational medicine, Vol. 15 (july 2017)
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5 p, 705.9 KB |
Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe-the Euro-epiME study from the European network EUROMENE : a protocol for a systematic review
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Estévez-López, Fernando (Ulster University) ;
Castro-Marrero, Jesús (Cornell University) ;
Wang, Xia (University of East Anglia) ;
Bakken, Inger Johanne (Norwegian Institute of Public Health) ;
Ivanovs, Andrejs (Riga Stradins University) ;
Nacul, Luis (London School of Hygiene & Tropical Medicine) ;
Sepúlveda, Nuno (University of Lisbon) ;
Strand, Elin B. (Oslo University Hospital (Oslo, Noruega)) ;
Pheby, Derek (Buckinghamshire New University) ;
Alegre Martín, José (Hospital Universitari Vall d'Hebron) ;
Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin) ;
Shikova, Evelina (National Center of Infectious and Parasitic Diseases) ;
Lorusso, Lorenzo (ASST-Lecco) ;
Capelli, Enrica (University of Pavia) ;
Sekulic, Slobodan (University of Novi Sad) ;
Lacerda, Eliana (London School of Hygiene & Tropical Medicine) ;
Murovska, Modra (Riga Stradins University) ;
Universitat Autònoma de Barcelona
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic disease involving central nervous system and immune system disorders, as well as cardiovascular abnormalities. ME/CFS is characterised by severe chronic fatigue lasting for at least 6 months, including clinical symptoms such as tender cervical or axillary lymph nodes, muscle pain, joint pain without swelling or redness, post-exertional malaise for more than 24 hours and unrefreshing sleep. [...]
2018 - 10.1136/bmjopen-2017-020817
BMJ open, Vol. 8 (september 2018)
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15 p, 708.0 KB |
Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe : Current Evidence and EUROMENE Research Recommendations for Epidemiology
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Estévez-López, Fernando (Erasmus MC University Medical Center) ;
Mudie, Kathleen (London School of Hygiene & Tropical Medicine) ;
Wang-Steverding, Xia (University of Warwick) ;
Bakken, Inger Johanne (Norwegian Institute of Public Health) ;
Ivanovs, Andrejs (Riga Stradins University) ;
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Nacul, Luis (London School of Hygiene & Tropical Medicine) ;
Alegre Martín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Zalewski, Paweł (Nicolaus Copernicus University in Toruń) ;
Słomko, Joanna (Nicolaus Copernicus University in Toruń) ;
Strand, Elin Bolle (Oslo University Hospital (Oslo, Noruega)) ;
Pheby, Derek (Buckinghamshire New University) ;
Shikova, Evelina (National Center of Infectious and Parasitic Diseases, Sofia) ;
Lorusso, Lorenzo (LASST-Lecco (Itàlia)) ;
Capelli, Enrica (University of Pavia) ;
Sekulic, Slobodan (University of Novi Sad) ;
Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin) ;
Sepúlveda, Nuno (University of Lisbon) ;
Murovska, Modra (Riga Stradins University) ;
Lacerda, Eliana (London School of Hygiene & Tropical Medicine) ;
Universitat Autònoma de Barcelona
This review aimed at determining the prevalence and incidence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Europe. We conducted a primary search in Scopus, PubMed and Web of Science for publications between 1994 and 15 June 2019 (PROSPERO: CRD42017078688). [...]
2020 - 10.3390/jcm9051557
Journal of clinical medicine, Vol. 9 (may 2020)
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11 p, 764.7 KB |
The SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) in myalgic encephalomyelitis/chronic fatigue syndrome : A meta-analysis of public DNA methylation and gene expression data
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Malato, João (Universidade de Lisboa) ;
Sotzny, Franziska (Charité - Universitätsmedizin Berlin) ;
Bauer, Sandra (Charité - Universitätsmedizin Berlin) ;
Freitag, Helma (Charité - Universitätsmedizin Berlin) ;
Fonseca, André (Universidade do Algarve) ;
Grabowska, Anna D. (Medical University of Warsaw) ;
Graça, Luís (Universidade de Lisboa) ;
Cordeiro, Clara (Universidade do Algarve) ;
Nacul, Luís (British Columbia Women's Hospital) ;
Lacerda, Eliana (London School of Hygiene & Tropical Medicine) ;
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin) ;
Westermeier, Francisco (Universidad Bernardo O'Higgins) ;
Sepúlveda, Nuno (London School of Hygiene & Tropical Medicine) ;
Universitat Autònoma de Barcelona
People with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) often report a high frequency of viral infections and flu-like symptoms during their disease course. Given that this reporting agrees with different immunological abnormalities and altered gene expression profiles observed in the disease, we aimed at answering whether the expression of the human angiotensin-converting enzyme 2 (ACE2), the major cell entry receptor for SARS-CoV-2, is also altered in these patients. [...]
2021 - 10.1016/j.heliyon.2021.e07665
Heliyon, Vol. 7 (july 2021) , p. e07665
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12 p, 347.3 KB |
Myalgic encephalomyelitis/chronic fatigue Syndrome (ME/CFS) : Investigating care practices pointed out to disparities in diagnosis and treatment across European Union
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Strand, Elin B. (Oslo University Hospital HF. CFS/ME Centre. Norwegian National Advisory Unit on CFS/ME) ;
Nacul, Luis (Faculty of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine) ;
Mengshoel, Anne Marit (University of Oslo) ;
Helland, Ingrid B. (Oslo University Hospital (Oslo, Noruega)) ;
Grabowski, Patricia (Charité - Universitätsmedizin Berlin) ;
Krumina, Angelika (Riga Stradins University) ;
Alegre Martín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Efrim-Budisteanu, Magdalena (Research Psychiatry Laboratory. "Alexandru Obregia" Clinical Hospital of Psychiatry) ;
Sekulic, Slobodan (Medical Faculty Novi Sad) ;
Pheby, Derek (University College London. Rayne Institute) ;
Sakkas, Giorgos K. (Live Laboratory. School of PE and Sport Sciences. University of Thessaly) ;
Adella Sirbu, Carmen (Central Military Emergency Hospital. Carol Davila) ;
Authier, François Jérôme (Lorraine University. Nancy University hospital. CHU de Nancy. Hôpitaux de Brabois) ;
Murovska, Modra (Riga Stradins University) ;
Lacerda, Eliana (Faculty of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine) ;
Estevez Lopez, Fernando (CVS/ME Medisch Centrum) ;
Scheibenbogen, C. (University Hospital Erlangen (Alemanya)) ;
Shi-Kova-Lekova, E. (National Center of Infectious and Parasitic Diseases) ;
Lorusso, Lorenzo (University of Pavia) ;
Berkis, U. (Riga Stradins University) ;
Westermeier, F. (FH Joanneum) ;
Riederer, M. (FH Joanneum) ;
Tobback, E. (Universitair Ziekenhuis Gent) ;
Meeus, Mira (Universiteit Antwerpen. Campus Drie Eiken) ;
Shikova-Lekova, E. ;
Nielsen, H. (PrivatHospitalet Danmark) ;
Brandslund, I. (Lillebaelt Hospital) ;
Polo, O. (Unesta Research Center) ;
De Korwin, J. D. (Lorraine University. Nancy University hospital. CHU de Nancy. Hôpitaux de Brabois) ;
Scheibenbogen, C. (University Hospital Erlangen (Alemanya)) ;
Harrer, T. (University Hospital Erlangen (Alemanya)) ;
Prusty, B. (Julius Maximilian University of Wuerzburg. Department of Microbiology. University of Wuerzburg Biozentrum) ;
Freitag, H. (Charité - Universitätsmedizin Berlin) ;
Trepel, D. (Trinity College Dublin. Trinity College. Office 0.81. Lloyd Building) ;
Cullinan, John (NUI Galway Discipline of Economics. NUI Galway) ;
Lorusso, Lorenzo (University of Pavia) ;
Capelli, Enrica (University of Pavia) ;
Nora-Krukle, Z. (Charité - Universitätsmedizin Berlin) ;
Rasa, S. (Charité - Universitätsmedizin Berlin) ;
Vermeulen, R. (CVS/ME Medisch Centrum) ;
Menhshoel, A. M. (University of Oslo) ;
Helland, I. B. (Oslo University Hospital (Oslo, Noruega)) ;
Zalewski, Paweł (Nicolaus Copernicus University in Torun Collegium Medicum) ;
Sepulveda, N. (Centre of Statistics and Application. University of Lisbon. Faculdade de Ciencias) ;
Sirbu, C. A. (Central Military Emergency Hospital. Carol Davila) ;
Sekulic, Slobodan (Medical Faculty Novi Sad) ;
Vukadinovic, M. (Novi Sad Business School) ;
Marusic, U. (Science and research centre Koper) ;
Pisot, R. ;
Castro-Marrero, Jesús. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Blanco, Julià (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Oltra, E. (Universidad Católica de Valencia) ;
Miro, J. (Universitat Rovira i Virgili. Departament de Psicologia) ;
Berquist, J. (Uppsala University Analytical Chemistry) ;
Blomberg, J. (Uppsala University. Medical Sciences. Academic Hospital) ;
Pheby, D. (University College London. Rayne Institute) ;
Edwards, J. (University College London. Rayne Institute) ;
Wang, X. (School of Pharmacy. Norwich Medical School. Faculty of Medicine and Health Sciences. University of East Anglia) ;
Universitat Autònoma de Barcelona
ME/CFS is a chronic, complex, multisystem disease that often limits the health and functioning of the affected patients. Diagnosing patients with ME/CFS is a challenge, and many different case definitions exist and are used in clinical practice and research. [...]
2019 - 10.1371/journal.pone.0225995
PloS one, Vol. 14 Núm. 12 (january 2019) , p. e0225995
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