|
1.
|
|
9 p, 745.8 KB |
The EMIF-AD Multimodal Biomarker Discovery study : Design, methods and cohort characteristics
/
Bos, Isabelle (Maastricht University) ;
Vos, Stephanie (Maastricht University) ;
Vandenberghe, Rik (Katholieke Universiteit Leuven) ;
Scheltens, Philip (Amsterdam UMC. University Medical Center) ;
Engelborghs, Sebastiaan (University of Antwerp) ;
Frisoni, Giovanni (IRCCS Instituto Centro San Giovanni di Dio Fatebenefratelli) ;
Molinuevo, José Luis (Fundació Pasqual Maragall) ;
Wallin, Anders (Institute of Neuroscience and Physiology) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, Julius (Lausanne University Hospital) ;
Martinez-Lage, Pablo (Centro de Investigación y Tecnología Agroalimentaria de Aragón) ;
Baird, Alison (University of Oxford) ;
Dobson, Richard (NIHR University College London Hospitals) ;
Legido-Quigley, Cristina (King's College London) ;
Sleegers, Kristel (University of Antwerp) ;
Van Broeckhoven, Christine (University of Antwerp) ;
Bertram, Lars (University of Oslo) ;
Ten Kate, Mara (Amsterdam UMC. University Medical Center) ;
Barkhof, Frederik (Amsterdam UMC. University Medical Center) ;
Zetterberg, Henrik (UK Dementia Research Institute) ;
Lovestone, Simon (University of Oxford) ;
Streffer, Johannes (Janssen Pharmaceutical Companies) ;
Visser, Pieter Jelle (Vrije Universiteit Amsterdam) ;
Universitat Autònoma de Barcelona
There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer's disease (AD) in the predementia stages and to predict the rate of decline. Therefore, we set up the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery (EMIF-AD MBD) study. [...]
2018 -  10.1186/s13195-018-0396-5
Alzheimer's research & therapy, Vol. 10 Núm. 1 (june 2018) , p. 64
|
|
|
2.
|
|
6 p, 731.5 KB |
A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood : Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort
/
Stamate, Daniel (University of London) ;
Kim, Min (Steno Diabetes Center Copenhagen) ;
Proitsi, Petroula (King's College London) ;
Westwood, Sarah (University of Oxford) ;
Baird, Alison (University of Oxford) ;
Nevado-Holgado, Alejo (University of Oxford) ;
Hye, Abdul (King's College London) ;
Bos, Isabelle (Amsterdam UMC) ;
Vos, Stephanie J.B. (Maastricht University) ;
Vandenberghe, Rik (Amsterdam UMC) ;
Teunissen, Charlotte E. (Amsterdam UMC. University Medical Center) ;
Kate, Mara Ten (Amsterdam UMC. University Medical Center) ;
Scheltens, Philip (Vrije Universiteit Amsterdam) ;
Gabel, Silvy (Laboratory for Cognitive Neurology) ;
Meersmans, Karen (Laboratory for Cognitive Neurology) ;
Blin, Olivier (Aix-Marseille Université) ;
Richardson, Jill (GlaxoSmithKline R&D) ;
De Roeck, Ellen (University of Antwerp) ;
Engelborghs, Sebastiaan (Vrije Universiteit Brussel (VUB)) ;
Sleegers, Kristel (Center for Molecular Neurology. VIB) ;
Bordet, Régis (University of Lille) ;
Ramit, Lorena (Hospital Clínic i Provincial de Barcelona) ;
Kettunen, Petronella (Sahlgrenska Academy at University of Gothenburg) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Verhey, Frans (Maastricht University) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Peyratout, Gwendoline (Lausanne University Hospital) ;
Tainta, Mikel (Fundacion CITA-alzheimer Fundazioa) ;
Johannsen, Peter (Copenhagen University Hospital) ;
Freund-Levi, Yvonne (Karolinska Institutet (Estocolm, Suècia)) ;
Frölich, Lutz (University of Heidelberg) ;
Dobricic, Valerija (University of Lübeck) ;
Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Molinuevo, José Luis (Universitat Pompeu Fabra) ;
Wallin, Anders (Sahlgrenska Academy at the University of Gothenburg) ;
Popp, Julius (Geneva University Hospitals) ;
Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ;
Bertram, Lars (University of Oslo) ;
Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ;
Streffer, Johannes (University of Antwerp) ;
Visser, Pieter J. (Amsterdam UMC) ;
Lovestone, Simon (Janssen-Cilag UK Ltd) ;
Legido-Quigley, Cristina (King's College London) ;
Universitat Autònoma de Barcelona
Machine learning (ML) may harbor the potential to capture the metabolic complexity in Alzheimer Disease (AD). Here we set out to test the performance of metabolites in blood to categorize AD when compared to CSF biomarkers. [...]
2019 - 10.1016/j.trci.2019.11.001
Alzheimer's & dementia, Vol. 5 (2019) , p. 933-938
|
|
|
3.
|
|
11 p, 783.1 KB |
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay
/
Shi, Liu (University of Oxford) ;
Westwood, Sarah (University of Oxford) ;
Baird, Alison L. (University of Oxford) ;
Winchester, Laura (University of Oxford) ;
Dobricic, Valerija (University of Lübeck) ;
Kilpert, Fabian (University of Lübeck) ;
Hong, Shengjun (University of Lübeck) ;
Franke, Andre (Christian-Albrechts-University of Kiel) ;
Hye, Abdul (King's College London) ;
Ashton, Nicholas J. (South London and Maudsley NHS Foundation) ;
Morgan, Angharad R. (Cardiff University) ;
Bos, Isabelle (Maastricht University) ;
Vos, Stephanie J.B. (Amsterdam UMC. University Medical Center) ;
Buckley, Noel J (University of Oxford) ;
Kate, Mara ten (Amsterdam UMC. University Medical Center) ;
Scheltens, Philip (Amsterdam UMC. University Medical Center) ;
Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ;
Gabel, Silvy (Laboratory for Cognitive Neurology) ;
Meersmans, Karen (Laboratory for Cognitive Neurology) ;
Engelborghs, Sebastiaan (VUB University Hospital Brussels (UZ Brussel)) ;
De Roeck, Ellen E. (Institute Born-Bunge. University of Antwerp) ;
Sleegers, Kristel (Center for Molecular Neurology. VIB) ;
Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Blin, Olivier (Aix-Marseille Université) ;
Richardson, Jill C. (GlaxoSmithKline R&D) ;
Bordet, Régis (University of Lille) ;
Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ;
Rami, Lorena (Universitat Pompeu Fabra) ;
Wallin, Anders (Sahlgrenska Academy at University of Gothenburg) ;
Kettunen, Petronella (University of Oxford) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Verhey, Frans (Maastricht University) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, Julius (Geneva University Hospitals) ;
Peyratout, Gwendoline (Lausanne University Hospital) ;
Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ;
Tainta, Mikel (CITA-Alzheimer Foundation) ;
Johannsen, Peter Copenhagen University Hospital ;
Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ;
Freund-Levi, Yvonne (King's College London) ;
Frölich, Lutz (University of Heidelberg) ;
Legido-Quigley, Cristina (Steno Diabetes Center) ;
Barkhof, Frederik (UCL Institutes of Neurology and Healthcare Engineering) ;
Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ;
Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ;
Baker, Susan (Janssen R&D) ;
Morgan, B.Paul (Cardiff University) ;
Streffer, Johannes (Janssen R&D. LLC) ;
Visser, Pieter Jelle (Karolinska Institutet (Estocolm, Suècia)) ;
Bertram, Lars (University of Oslo) ;
Lovestone, Simon (University of Oxford) ;
Nevado-Holgado, Alejo (University of Oxford) ;
Universitat Autònoma de Barcelona
Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. [...]
2019 - 10.1016/j.jalz.2019.06.4951
Alzheimer's & Dementia, Vol. 15 Núm. 11 (november 2019) , p. 1478-1488
|
|
|
4.
|
|
22 p, 986.7 KB |
Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort
/
Kim, Min (Steno Diabetes Center Copenhagen) ;
Snowden, Stuart (University of Cambridge) ;
Suvitaival, Tommi (Steno Diabetes Center Copenhagen) ;
Ali, Ashfaq (Steno Diabetes Center Copenhagen) ;
Merkler, David J. (University of South Florida) ;
Ahmad, Tahmina (King's College London) ;
Westwood, Sarah (University of Oxford) ;
Baird, Alison (University of Oxford) ;
Proitsi, Petroula (King's College London) ;
Nevado-Holgado, Alejo (University of Oxford) ;
Hye, Abdul (Steno Diabetes Center Copenhagen) ;
Bos, Isabelle (Maastricht University) ;
Vos, Stephanie (Maastricht University) ;
Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ;
Teunissen, Charlotte (Amsterdam Neuroscience) ;
ten Kate, Mara (Amsterdam Neuroscience) ;
Scheltens, Philip (Amsterdam UMC. University Medical Center) ;
Gabel, Silvy (KU Leuven) ;
Meersmans, Karen (KU Leuven) ;
Blin, Olivier ;
Richardson, Jill (GlaxoSmithKline R&D) ;
De Roeck, Ellen (University of Antwerp) ;
Sleegers, Kristel (VIB) ;
Bordet, Régis (University of Lille) ;
Rami Gonzalez, Lorena (Hospital Clínic i Provincial de Barcelona) ;
Kettunen, Petronella (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Verhey, Frans (Maastricht University) ;
Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Peyratout, Gwendoline (Lausanne University Hospital) ;
Tainta, Mikel (CITA-Alzheimer Foundation) ;
Johannsen, Peter (Copenhagen University Hospital) ;
Freund-Levi, Yvonne (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Frölich, Lutz (University of Heidelberg) ;
Dobricic, Valerija (University of Lübeck) ;
Engelborghs, Sebastiaan (University Hospital Antwerp (Bèlgica)) ;
Frisoni, Giovanni B. (University of Geneva) ;
Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ;
Wallin, Anders (University of Gothenburg) ;
Popp, Julius (Geneva University Hospitals) ;
Martinez-Lage, Pablo (CITA-Alzheimer Foundation) ;
Bertram, Lars (University of Lübeck) ;
Barkhof, Frederik (Amsterdam Neuroscience) ;
Ashton, Nicholas J (University of Gothenburg) ;
Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ;
Zetterberg, Henrik (UK Dementia Research Institute) ;
Streffer, Johannes (Janssen Pharmaceutical Companies) ;
Visser, Pieter J. (Amsterdam Neuroscience) ;
Lovestone, Simon (University of Oxford) ;
Legido-Quigley, Cristina (Steno Diabetes Center Copenhagen) ;
Universitat Autònoma de Barcelona
A critical and as-yet unmet need in Alzheimer's disease (AD) is the discovery of peripheral small molecule biomarkers. Given that brain pathology precedes clinical symptom onset, we set out to test whether metabolites in blood associated with pathology as indexed by cerebrospinal fluid (CSF) AD biomarkers. [...]
2019 - 10.1016/j.jalz.2019.03.004
Alzheimer's & Dementia, Vol. 15 Núm. 6 (june 2019) , p. 817-827
|
|
|
5.
|
|
12 p, 1.1 MB |
Inflammatory biomarkers in Alzheimer's disease plasma
/
Morgan, Angharad R. (Systems Immunity Research Institute and UK Dementia Research Institute Cardiff, Cardiff University (Regne Unit)) ;
Touchard, Samuel (Systems Immunity Research Institute and UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University (Regne Unit)) ;
Leckey, Claire A. (Cardiff University (Regne Unit)) ;
O'Hagan, Caroline (Cardiff University (Regne Unit)) ;
Nevado-Holgado, Alejo (University of Oxford (Regne Unit)) ;
Barkhof, Frederik (University College London) ;
Bertram, Lars (Max Planck Institute for Molecular Genetics (Alemanya)) ;
Blin, Olivier (Aix-Marseille University (França)) ;
Bos, Isabelle (Maastricht University (Països Baixos)) ;
Dobricic, Valerija (University of Lübeck (Alemanya)) ;
Engelborghs, Sebastiaan (Institute Born-Bunge (Bèlgica)) ;
Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli (Brescia, Itàlia)) ;
Froelich, Lutz (University of Heidelberg (Alemanya)) ;
Gabel, Silvy (Laboratory for Cognitive Neurology (Leuven, Bèlgica)) ;
Johannsen, Peter (Karolinska Institutet (Stockholm, Sweden)) ;
Kettunen, Petronella (University of Gothenburg (Gothenburg, Suècia)) ;
Kłoszewska, Iwona (Medical University of Lodz (Lodz, Poland)) ;
Legido-Quigley, Cristina (Imperial College London) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Martinez-Lage, Pablo (Fundación CITA-Alzheimer Fundazioa (San Sebastian, Spain)) ;
Mecocci, Patrizia (University of Perugia (Itàlia)) ;
Meersmans, Karen (Laboratory for Cognitive Neurology (Bèlgica)) ;
Molinuevo, José Luis (Universitat Pompeu Fabra) ;
Peyratout, Gwendoline (Lausanne University Hospital (Suïssa)) ;
Popp, Julius (Hopitaux Universitaires Geneve and Universite de Geneve (Suïssa)) ;
Richardson, Jill (GlaxoSmithKline R&D (Regne Unit)) ;
Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Scheltens, Philip (Vrije Universiteit (Països Baixos)) ;
Streffer, Johannes (University of Antwerp) ;
Soininen, Hikka (University of Eastern Finland) ;
Tainta, Mikel (Fundación CITA Alzheimer (Sant Sebastià, País Basc)) ;
Teunissen, Charlotte E (University Hospitals Leuven (Bèlgica)) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Vandenberghe, Rik (Amsterdam University Medical Centers (Països Baixos)) ;
Visser, Pieter Jelle (Maastricht University (Països Baixos)) ;
Vos, Stephanie (Maastricht University (Països Baixos)) ;
Wahlund, Lars Olof (Karolinska Institutet (Estocolm, Suècia)) ;
Wallin, Anders (University of Gothenburg Sahlgrenska Academy) ;
Westwood, Sarah (University of Oxford (Regne Unit)) ;
Zetterberg, Henrik (UK Dementia Research Institute (Londres, Regne Unit)) ;
Lovestone, Simon (University of Oxford (Regne Unit)) ;
Morgan, B. Paul (Cardiff University (Regne Unit)) ;
Bullmore, Edward (University of Cambridge (Regne Unit)) ;
Bhatti, Junaid (University of Cambridge (Regne Unit)) ;
Chamberlain, Samuel J. (University of Cambridge (Regne Unit)) ;
Correia, Marta Morgado (University of Cambridge (Regne Unit)) ;
Crofts, Anna L. (Université de Sherbrooke (Canadà)) ;
Dickinson, Amber (Addenbroke's Hospital (Cambridge, Regne Unit)) ;
Foster, Andy C. (Cambridgeshire and Peterborough NHS Foundation Trust (Regne Unit)) ;
Kitzbichler, Manfred G. (University of Cambridge (Regne Unit)) ;
Knight, Clare (Cambridgeshire and Peterborough NHS Foundation Trust (Regne Unit)) ;
Lynall, Mary-Ellen (University of Cambridge (Regne Unit)) ;
Maurice, Christina (University of Cambridge (Regne Unit)) ;
O'Donnell, Ciara M. (University College London (Regne Unit)) ;
Pointon, Linda J. (University of Cambridge (Regne Unit)) ;
St George Hyslop, Peter (University of Cambridge (Regne Unit)) ;
Turner, Lorinda (University of Cambridge (Regne Unit)) ;
Vertes, Petra E. (University of Cambridge (Regne Unit)) ;
Widmer, Barry (University of Cambridge (Regne Unit)) ;
Williams, Guy (University of Cambridge (Regne Unit)) ;
Cavanagh, Jonathan T. O. (Karolinska Institutet (Estocolm, Suècia)) ;
Deith, Catherine (Southern General Hospital Glasgow (Escòcia)) ;
Farmer, Scott (Bio Med Sciences Inc.(Galveston, Estats Units)) ;
McClean, John (NHS Greater Glasgow and Clyde (Glasgow, Escòcia)) ;
McColl, Alison (College of Medical, Veterinary & Life Sciences (Glasgow, Escòcia)) ;
McPherson, Andrew (Addenbrooke's Hospital (Cambridge, Regne Unit)) ;
Scouller, Paul (Addenbrooke's Hospital (Cambridge, Regne Unit)) ;
Sutherland, Murray (NHS Greater Glasgow and Clyde (Glasgow, Escòcia)) ;
Boddeke, Erik W.G.M. (Københavns UniversitetThe institution (Copenhaguen, Dinamarca)) ;
Khan, Shahid (GlaxoSmithKline plc. (Regne Unit)) ;
Murphy, Philip Stephen (GlaxoSmithKline plc. (Regne Unit)) ;
Parker, Christine A. (Wellcome Trust (Londres, Regne Unit)) ;
Patel, Jai (GlaxoSmithKline plc. (Regne Unit)) ;
Jones, Declan (Janssen Pharmaceuticals (Titusville, Estats Units)) ;
de Boer, Peter (Janssen Research & Development (Beerse, Bèlgica)) ;
Kemp, John A. (KU Leuven- University Hospital Leuven (Bèlgica)) ;
Drevets, Wayne Curtis (Janssen Research & Development (Beerse, Bèlgica)) ;
Nye, Jeffrey S. (Janssen Research & Development (Beerse, Bèlgica)) ;
Wittenberg, Gayle M. (Janssen Research & Development (Beerse, Bèlgica)) ;
Isaac, John T.R. (Johnson & Johnson (Estats Units)) ;
Bhattacharya, Anindya (Janssen Research & Development (Beerse, Bèlgica)) ;
Carruthers, Niicholas L. (Janssen Research & Development (Beerse, Bèlgica)) ;
Kolb, Hartmuth Christian (Janssen Research & Development (Beerse, Bèlgica)) ;
Pariante, Carmine M. (King's College London (Regne Unit)) ;
Turkheimer, Federico (King's College London (Regne Unit)) ;
Barker, Gareth John (King's College London (Regne Unit)) ;
Byrom, Heidi (King's College London (Regne Unit)) ;
Cash, Diana (King's College London (Regne Unit)) ;
Cattaneo, Annamaria (King's College London (Regne Unit)) ;
Gee, Anthony (King's College London (Regne Unit)) ;
Hastings, Caitlín N.M. (King's College London (Regne Unit)) ;
Mariani, Nicole (King's College London (Regne Unit)) ;
McLaughlin, Anna Patricia (King's College London (Regne Unit)) ;
Mondelli, Valeria (King's College London (Regne Unit)) ;
Nettis, Maria Antonietta (King's College London (Regne Unit)) ;
Nikkheslat, Naghmeh (King's College London (Regne Unit)) ;
Randall, Karen (King's College London (Regne Unit)) ;
Sheridan, Hannah C. (King's College London (Regne Unit)) ;
Simmons, Camilla (King's College London (Regne Unit)) ;
Singh, Nisha (King's College London (Regne Unit)) ;
Van Loo, Victoria (King's College London (Regne Unit)) ;
Vicente-Rodríguez, Marta (King's College London (Regne Unit)) ;
Wood, Tobias (King's College London (Regne Unit)) ;
Worrell, Courtney (King's College London (Regne Unit)) ;
Zajkowska, Zuzanna (King's College London (Regne Unit)) ;
Plath, Niels (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Egebjerg, Jan (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Eriksson, Hans (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Gastambide, Francois (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Adams, Karen Husted (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Jeggo, Ross D. (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Thomsen, Christian (Aalborg Universitetshospital (Aalborg, Dinamarca)) ;
Pederson, Jan Torleif (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Campbell, Brian M. (Lundbeck Research USA Inc. (Deerfield, Estats Units)) ;
Möller, Thomas (Lundbeck Research USA Inc. (Deerfield, Estats Units)) ;
Nelson, Bob (H. Lundbeck A/S (Copenhagen, Dinamarca)) ;
Zorn, Stevin H. (Lundbeck Research USA Inc. (Deerfield, Estats Units)) ;
O'Connor, Jason (University of Texas Hlth Sci Ctr San Antonio(Estats Units)) ;
Attenburrow, Mary Jane (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ;
Baird, Alison (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ;
Benjamin, Jithen (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ;
Clare, Stuart (John Radcliffe Hosp, Oxford Ctr Funct MRI Brain (Oxford, Anglaterra)) ;
Cowen, Philip (University of Oxford (Anglaterra)) ;
Huang, I-Shuo Wade (Kennedy Inst Rheumatol (Oxford, Anglaterra)) ;
Hurley, Samuel A. (University of Wisconsin-Madison (Madison, Estats Units)) ;
Jones, Helen (Warneford Hosp, NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ;
Mada, Francisca (Neurosciences & Neurology) ;
Nevado-Holgado, Alejo (University of Oxford (Anglaterra)) ;
Oladejo, Akitayo (Metropolitan Hospital Center (New York, Estats Units)) ;
Ribe, Elena (King's College London (Londres, Anglaterra)) ;
Smith, Katy (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ;
Vyas, Anviti (University of Oxford (Oxford, Anglaterra)) ;
Hughes, Zoe (Praxis Precision Medicines (Cambridge, Regne Unit)) ;
Balice-Gordon, Rita (Sanofi S.A. (Gentilly, França)) ;
Duerr, James M. (Pfizer Inc.(New York, Estats Units)) ;
Piro, Justin R. (Pfizer Inc.(New York, Estats Units)) ;
Sporn, Jonathan (Gilgamesh Pharmaceut (New York, Estats Units)) ;
Perry, V. Hugh (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ;
Cleal, Madeleine (University of Portsmouth (Anglaterra)) ;
Fryatt, Gemma (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ;
Gomez-Nicola, Diego (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ;
Mancuso, Renzo (University of Southampton (Anglaterra)) ;
Reynolds, Richard (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ;
Harrison, Neil (University fo Sussex (Brighton, Anglaterra)) ;
Cercignani, Mara (University fo Sussex (Brighton, Anglaterra)) ;
Clarke, Charlotte L. (University of Sussex (Brighton, Regne Unit)) ;
Hoskins, Elizabeth (Sussex Partnership NHS Foundation Trust (Worthing, Regne Unit)) ;
Kohn, Charmaine (Sussex Partnership NHS Foundation Trust (Worthing, Regne Unit)) ;
Murray, Rosemary (Addenbrooke's Hospital (Cambridge, Regne Unit)) ;
Wilcock, Lauren (Sussex Partnership NHS Fdn Trust (Hove, Anglaterra)) ;
Wlazly, Dominika (Brighton and Sussex University Hospitals NHS Trust (Sussex, Anglaterra)) ;
Mount, Howard T.J. (University of Toronto (Toronto, Canadà)) ;
Universitat Autònoma de Barcelona
Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. A hypothesis-led plasma biomarker search was conducted in the context of international multicenter studies. [...]
2019 - 10.1016/j.jalz.2019.03.007
Alzheimer's & Dementia, Vol. 15 Núm. 6 (june 2019) , p. 776-787
|
|
|
6.
|
|
13 p, 162.5 KB |
Validation of plasma proteomic biomarkers relating to brain amyloid burden in the EMIF-Alzheimer's disease multimodal biomarker discovery cohort
/
Westwood, Sarah (University of Oxford) ;
Baird, Alison L (University of Oxford) ;
Anand, Sneha N. (University of Oxford) ;
Nevado-Holgado, Alejo (University of Oxford) ;
Kormilitzin, Andrey (University of Oxford) ;
Shi, Liu (University of Oxford) ;
Hye, Abdul (King's College London) ;
Ashton, Nicholas J (University of Gothenburg) ;
Morgan, Angharad R. (Cardiff University) ;
Bos, Isabelle (Maastricht University) ;
Vos, Stephanie J.B. (Maastricht University) ;
Baker, Susan (Janssen R and D) ;
Buckley, Noel J (University of Oxford) ;
Ten Kate, Mara (Vrije Universiteit University Medical Center) ;
Scheltens, Philip (Vrije Universiteit University Medical Center) ;
Teunissen, Charlotte E. (Vrije Universiteit University Medical Center) ;
Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ;
Gabel, Silvy (Ku Leuven) ;
Meersmans, Karen (Ku Leuven) ;
Engelborghs, Sebastiaan (Vrije Universiteit Brussel (VUB)) ;
De Roeck, Ellen E. (Vrije Universiteit Brussel (VUB)) ;
Sleegers, Kristel (Center for Molecular Neurology) ;
Frisoni, Giovanni B. (Irccs Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Blin, Olivier (Aix-Marseille Université) ;
Richardson, Jill C. (GlaxoSmithKline R and D) ;
Bordet, Régis (University of Lille) ;
Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ;
Rami, Lorena (Universitat Pompeu Fabra) ;
Wallin, Anders (Sahlgrenska Academy at University of Gothenburg) ;
Kettunen, Petronella (Sahlgrenska Academy at University of Gothenburg) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Verhey, Frans (Maastricht University) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, Julius (Geneva University Hospitals) ;
Peyratout, Gwendoline (Lausanne University Hospital) ;
Martinez-Lage, Pablo (Geneva University Hospitals) ;
Tainta, Mikel (CITA-Alzheimer Foundation) ;
Johannsen, Peter (Copenhagen University Hospital) ;
Freund-Levi, Yvonne (Karolinska Institutet (Estocolm, Suècia)) ;
Frölich, Lutz (University of Heidelberg) ;
Dobricic, Valerija (University of Lübeck) ;
Legido-Quigley, Cristina (Steno Diabetes Center) ;
Bertram, Lars (University of Oslo) ;
Barkhof, Frederik (Ucl Institutes of Neurology and Healthcare Engineering) ;
Zetterberg, Henrik (Ucl Institute of Neurology) ;
Morgan, B.Paul (Cardiff University) ;
Streffer, Johannes (Janssen R and D. Llc) ;
Visser, Pieter Jelle (Vu University Medical Center) ;
Lovestone, Simon (Janssen R and D) ;
Universitat Autònoma de Barcelona
We have previously investigated, discovered, and replicated plasma protein biomarkers for use to triage potential trials participants for PET or cerebrospinal fluid measures of Alzheimer's disease (AD) pathology. [...]
2020 - 10.3233/JAD-190434
Journal of Alzheimer's disease, Vol. 74 Núm. 1 (2020) , p. 213-225
|
|
|
7.
|
|
12 p, 1.3 MB |
Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
/
Hong, S. (University of Lübeck) ;
Prokopenko, D. (Massachusetts General Hospital) ;
Dobricic, V. (University of Lübeck) ;
Kilpert, F. (University of Lübeck) ;
Bos, I. (Vrije Universiteit Amsterdam) ;
Vos, S.J.B. (Maastricht University) ;
Tijms, Betty M (Vrije Universiteit Amsterdam) ;
Andreasson, Ulf (Sahlgrenska University Hospital (Suècia)) ;
Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ;
Vandenberghe, R. (University Hospitals Leuven (Bèlgica)) ;
Cleynen, I. (KU Leuven) ;
Gabel, Silvy (KU Leuven) ;
Schaeverbeke, J. (KU Leuven) ;
Scheltens, Philip (Vrije Universiteit Amsterdam) ;
Teunissen, C.E. (Vrije Universiteit) ;
Niemantsverdriet, E. (University of Antwerp) ;
Engelborghs, Sebastiaan (UZ Brussel and Vrije Universiteit Brussel (VUB)) ;
Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Blin, Olivier (Aix-Marseille Université) ;
Richardson, J.C. (GlaxoSmithKline R&D) ;
Bordet, Régis (University of Lille) ;
Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ;
Rami Gonzalez, Lorena (Hospital Clínic i Provincial de Barcelona) ;
Kettunen, P. (University of Oxford) ;
Wallin, Anders (University of Gothenburg) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, J. (Lausanne University Hospital) ;
Peyratout, Gwendoline (Lausanne University Hospital) ;
Martinez-Lage, P. (CITA-Alzheimer Foundation) ;
Tainta, M. (CITA-Alzheimer Foundation) ;
Dobson, R.J.B. (University College London) ;
Legido-Quigley, Cristina (King's College London) ;
Sleegers, K. (University of Antwerp) ;
Van Broeckhoven, C. (University of Antwerp) ;
ten Kate, M. (Amsterdam Neuroscience) ;
Barkhof, Frederik (University College London) ;
Zetterberg, H. (UK Dementia Research Institute) ;
Lovestone, S. (University of Oxford) ;
Streffer, J. (UCB Biopharma SPRL) ;
Wittig, M. (Christian-Albrechts-University of Kiel) ;
Franke, Andre (Christian-Albrechts-University of Kiel) ;
Tanzi, R.E. (Massachusetts General Hospital) ;
Visser, Pieter Jelle (Vrije Universiteit Amsterdam) ;
Bertram, Lars (University of Oslo) ;
Universitat Autònoma de Barcelona
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and the most common form of dementia in the elderly. Susceptibility to AD is considerably determined by genetic factors which hitherto were primarily identified using case-control designs. [...]
2020 - 10.1038/s41398-020-01074-z
Translational psychiatry, Vol. 10 Núm. 1 (december 2020) , p. 403
|
|
|
8.
|
|
11 p, 1.4 MB |
APOE ϵ4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease
/
Konijnenberg, E. (Alzheimer Center Amsterdam) ;
Tijms, Betty M (Alzheimer Center Amsterdam) ;
Gobom, J. (University of Gothenburg) ;
Dobricic, V. (University of Lübeck) ;
Bos, Isabelle (Maastricht University) ;
Vos, S. (Maastricht University) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Verhey, F. (Maastricht University) ;
Popp, J. (Lausanne University Hospital) ;
Martinez-Lage, P. (CITA-Alzheimer Foundation) ;
Vandenberghe, R. (University Hospitals Leuven (Bèlgica)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Frölich, L. (University of Heidelberg) ;
Lovestone, S. (Janssen RandD) ;
Streffer, J. (Janssen RandD) ;
Bertram, Lars (University of Oslo) ;
Blennow, Kaj (University of Gothenburg) ;
Teunissen, C.E. (Vrije Universiteit Amsterdam) ;
Veerhuis, R. (Vrije Universiteit Amsterdam) ;
Smit, A.B. (Vrije Universiteit Amsterdam) ;
Scheltens, P. (Vrije Universiteit Amsterdam) ;
Zetterberg, H. (UK Dementia Research Institute) ;
Visser, P.J. (Karolinska Instutet) ;
Universitat Autònoma de Barcelona
Aggregation of amyloid β into plaques in the brain is one of the earliest pathological events in Alzheimer's disease (AD). The exact pathophysiology leading to dementia is still uncertain, but the apolipoprotein E (APOE) ϵ4 genotype plays a major role. [...]
2020 - 10.1186/s13195-020-00628-z
Alzheimer's research & therapy, Vol. 12 Núm. 1 (27 2020) , p. 65
|
|
|
9.
|
|
12 p, 1.2 MB |
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis
/
Gao, Yixin (Xuzhou Medical University) ;
Wang, Ting (Xuzhou Medical University) ;
Yu, Xinghao (Xuzhou Medical University) ;
Ferrari, Raffaele (Russell Square House) ;
Hernandez, Dena G. (Queen Square) ;
Nalls, Michael A. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ;
Rohrer, Jonathan D. (Queen Square) ;
Ramasamy, Adaikalavan (University of Oxford) ;
Kwok, John B.J. (University of New South Wales) ;
Dobson-Stone, Carol (University of New South Wales) ;
Brooks, William S. (University of New South Wales) ;
Schofield, Peter R. (Neuroscience Research Australia) ;
Halliday, Glenda M. (Neuroscience Research Australia) ;
Hodges, John R. (Neuroscience Research Australia) ;
Piguet, Olivier (Neuroscience Research Australia) ;
Bartley, Lauren (Neuroscience Research Australia) ;
Thompson, Elizabeth (University of Adelaide) ;
Haan, Eric (University of Adelaide) ;
Hernández, Isabel (Institut Català de Neurociéncies Aplicades) ;
Ruiz, Agustín (Institut Català de Neurociéncies Aplicades) ;
Boada, Mercè (Institut Català de Neurociéncies Aplicades) ;
Borroni, Barbara (University of Brescia) ;
Padovani, Alessandro (University of Brescia) ;
Cruchaga, Carlos (Washington University School of Medicine) ;
Cairns, Nigel J. (Washington University) ;
Benussi, Luisa (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Binetti, Giuliano (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Ghidoni, Roberta (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ;
Forloni, Gianluigi (IRCCS Istituto di Ricerche Farmacologiche. "Mario Negri") ;
Albani, Diego (IRCCS Istituto di Ricerche Farmacologiche. "Mario Negri") ;
Galimberti, Daniela (IRCCS Ospedale Maggiore Policlinico) ;
Fenoglio, Chiara (IRCCS Ospedale Maggiore Policlinico) ;
Serpente, Maria (IRCCS Ospedale Maggiore Policlinico) ;
Scarpini, Elio (University of Milan) ;
Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Waldö, Maria Landqvist (Lund University) ;
Nilsson, Karin (Lund University) ;
Nilsson, Christer (Lund University) ;
Mackenzie, Ian R.A. (University of British Columbia) ;
Hsiung, Ging-Yuek R. (University of British Columbia) ;
Mann, David M. A. (Salford Royal Hospital) ;
Grafman, Jordan (Northwestern University) ;
Morris, Christopher M. (Newcastle University) ;
Attems, Johannes (Newcastle University) ;
Griffiths, Timothy D. (Newcastle University Medical School) ;
McKeith, Ian G. (Newcastle University) ;
Thomas, Alan J. (Newcastle University) ;
Pietrini, Pietro (IMT School for Advanced Studies) ;
Huey, Edward D. (Columbia University) ;
Wassermann, Eric M. (National Insititutes of Health) ;
Baborie, Atik (University of Alberta Edmonton) ;
Jaros, Evelyn (Newcastle University) ;
Tierney, Michael C. (National Insititutes of Health) ;
Pastor, Pau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Razquin, Cristina (Universidad de Navarra) ;
Ortega-Cubero, Sara (Universidad de Navarra) ;
Alonso, Elena (Universidad de Navarra) ;
Perneczky, Robert (West London Mental Health Trust) ;
Diehl-Schmid, Janine (Technische Universität München) ;
Alexopoulos, Panagiotis (Technische Universität München) ;
Kurz, Alexander (Technische Universität München) ;
Rainero, Innocenzo (A.O. Città della Salute e della Scienza di Torino) ;
Rubino, Elisa (A.O. Città della Salute e della Scienza di Torino) ;
Pinessi, Lorenzo (A.O. Città della Salute e della Scienza di Torino) ;
Rogaeva, Ekaterina (University of Toronto) ;
St George Hyslop, Peter (University of Cambridge) ;
Rossi, Giacomina (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Tagliavini, Fabrizio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Giaccone, Giorgio (Fondazione IRCCS Istituto Neurologico Carlo Besta) ;
Rowe, James B. (Behavioural and Clinical Neuroscience Institute) ;
Schlachetzki, Johannes C. M. (University of California San Diego) ;
Uphill, James (University College London. Institute of Neurology) ;
Collinge, John (University College London. Institute of Neurology) ;
Mead, Simon (University College London. Institute of Neurology) ;
Danek, Adrian (German Center for Neurodegenerative Diseases (DZNE)) ;
Van Deerlin, Vivianna M. (University of Pennsylvania Perelman School of Medicine) ;
Grossman, Murray (University of Pennsylvania Perelman School of Medicine) ;
Trojanowski, John Q. (University of Pennsylvania Perelman School of Medicine) ;
van der Zee, Julie (University of Antwerp) ;
Cruts, Marc (University of Antwerp) ;
Van Broeckhoven, Christine (University of Antwerp) ;
Cappa, Stefano F. (Vita-Salute University and San Raffaele Scientific Institute) ;
Leber, Isabelle (CNRS UMR 7225) ;
Hannequin, Didier (Rouen University Hospital (França)) ;
Golfier, Véronique (CH Saint Brieuc) ;
Vercelletto, Martine (CHU Nantes) ;
Brice, Alexis (AP-HP. Hôpital de la Salpêtrière) ;
Nacmias, Benedetta (University of Florence) ;
Sorbi, Sandro (University of Florence and IRCCS "Don Carlo Gnocchi" Firenze) ;
Bagnoli, Silvia (University of Florence) ;
Piaceri, Irene (University of Florence) ;
Nielsen, Jørgen E. (Copenhagen University Hospital) ;
Hjermind, Lena E. (University of Copenhagen) ;
Riemenschneider, Matthias (Saarland University) ;
Mayhaus, Manuel (Saarland University) ;
Ibach, Bernd (University Regensburg) ;
Gasparoni, Gilles (Saarland University) ;
Pichler, Sabrina (Saarland University) ;
Gu, Wei (University of Luxembourg) ;
Rossor, Martin N. (Queen Square) ;
Fox, Nick C. (University College London Queen Square Institute of Neurology. Dementia Research Centre) ;
Warren, Jason D. (Queen Square) ;
Spillantini, Maria Grazia (University of Cambridge) ;
Morris, Huw R. (Russell Square House) ;
Rizzu, Patrizia (German Center for Neurodegenerative Diseases-Tübingen) ;
Heutink, Peter (German Center for Neurodegenerative Diseases-Tübingen) ;
Snowden, Julie S. (University of Manchester) ;
Rollinson, Sara (University of Manchester) ;
Richardson, Anna (University of Manchester) ;
Gerhard, Alexander (The University of Manchester) ;
Bruni, Amalia C. (ASPCZ) ;
Maletta, Raffaele (ASPCZ) ;
Frangipane, Francesca (ASPCZ) ;
Cupidi, Chiara (ASPCZ) ;
Bernardi, Livia (ASPCZ) ;
Anfossi, Maria (ASPCZ) ;
Gallo, Maura (ASPCZ) ;
Conidi, Maria Elena (ASPCZ) ;
Smirne, Nicoletta (ASPCZ) ;
Rademakers, Rosa (Mayo Clinic Jacksonville) ;
Baker, Matt (Mayo Clinic Jacksonville) ;
Dickson, Dennis W. (Mayo Clinic Jacksonville) ;
Graff-Radford, Neill R. (Mayo Clinic Jacksonville) ;
Petersen, Ronald C. (Mayo Clinic Rochester) ;
Knopman, David (Mayo Clinic Rochester) ;
Josephs, Keith A. (Mayo Clinic Rochester) ;
Boeve, Bradley (Mayo Clinic Rochester) ;
Parisi, Joseph E. (Mayo Clinic Rochester) ;
Seeley, William W. (University of California) ;
Miller, Bruce L. (University of California) ;
Karydas, Anna M. (University of California) ;
Rosen, Howard (University of California) ;
van Swieten, John C. (VU University Medical Centre) ;
Dopper, Elise G. P. (Erasmus Medical Centre) ;
Seelaar, Harro (Erasmus Medical Centre) ;
Pijnenburg, Yolande A. L. (VU University Medical Centre) ;
Scheltens, Philip (VU University Medical Centre) ;
Logroscino, Giancarlo (University of Bari) ;
Capozzo, Rosa (University of Bari) ;
Novelli, Valeria (Fondazione Policlinico Universitario A. Gemelli) ;
Puca, Annibale A. (University of Salerno) ;
Franceschi, Massimo (IRCCS Multimedica) ;
Postiglione, Alfredo (University of Naples Federico II) ;
Milan, Graziella (Geriatric Center Frullone- ASL Napoli 1 Centro) ;
Sorrentino, Paolo (Geriatric Center Frullone- ASL Napoli 1 Centro) ;
Kristiansen, Mark (Institute of Child Health (ICH)) ;
Chiang, Huei-Hsin (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Graff, Caroline (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Pasquier, Florence (Univ Lille) ;
Rollin, Adeline (Univ Lille) ;
Deramecourt, Vincent (Univ Lille) ;
Lebouvier, Thibaud (Univ Lille) ;
Kapogiannis, Dimitrios (National Institute on Aging (NIA/NIH)) ;
Ferrucci, Luigi (National Institute on Aging (Baltimore, Estats Units d'Amèrica)) ;
Pickering-Brown, S. (University of Manchester) ;
Singleton, Andrew B. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ;
Hardy, John (Russell Square House) ;
Momeni, Parastoo (Texas Tech University Health Science Center) ;
Zhao, Huashuo (Xuzhou Medical University) ;
Zeng, Ping (Xuzhou Medical University) ;
Universitat Autònoma de Barcelona
We employed Mendelian randomization (MR) to evaluate the causal relationship between leukocyte telomere length (LTL) and amyotrophic lateral sclerosis (ALS) with summary statistics from genome-wide association studies (n = ~ 38,000 for LTL and ~ 81,000 for ALS in the European population; n = ~ 23,000 for LTL and ~ 4,100 for ALS in the Asian population). [...]
2020 - 10.1038/s41598-020-68848-9
Scientific reports, Vol. 10 Núm. 1 (january 2020) , p. 12184
|
|
|
10.
|
|
14 p, 1.6 MB |
Characteristics of subjective cognitive decline associated with amyloid positivity
/
Janssen, Olin (Maastricht University. School for Mental Health and Neuroscience) ;
Jansen, W.J. (Maastricht University. School for Mental Health and Neuroscience) ;
Vos, S.J.B. (Maastricht University. School for Mental Health and Neuroscience) ;
Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Parnetti, Lucilla (Section of Neurology. Center for Memory Disturbances - Lab. of Clinical Neurochemistry. Department of Medicine and Surgery. University of Perugia) ;
Gabryelewicz, T. (Department of Neurodegenerative Disorders. Mossakowski Medical Research Centre. Polish Academy of Sciences) ;
Fladby, T. (Department of Neurology. Akershus University Hospital) ;
Molinuevo, José Luis (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Villeneuve, S. (Centre for Studies on Prevention of Alzheimer's Disease (StOP-AD) Centre) ;
Hort, J. (International Clinical Research Center. St. Anne's University Hospital) ;
Epelbaum, S. (Inserm Sorbonne Université. Inria. Aramis project-team. Paris Brain Institute - Institut du Cerveau (ICM)) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Engelborghs, Sebastiaan (Vrije Universiteit Brussel. (VUB) Brussels. and University of Antwerp) ;
van der Flier, W.M. (Alzheimer Center Amsterdam. Department of Neurology. Amsterdam Neuroscience. Amsterdam UMC. Vrije Universiteit Amsterdam) ;
Landau, S. (Helen Wills Neuroscience Institute. University of California) ;
Popp, J. (Old Age Psychiatry. University Hospital of Lausanne) ;
Wallin, Anders (Institute of Neuroscience and Physiology. Sahlgrenska Academy at University of Gothenburg) ;
Scheltens, P. (Alzheimer Center Amsterdam. Department of Neurology. Amsterdam Neuroscience. Amsterdam UMC. Vrije Universiteit Amsterdam) ;
Rikkert, M.O. (Department of Geriatric Medicine. Radboud Alzheimer Center. Radboud University Medical Center) ;
Snyder, P.J. (Kingston. The University of Rhode Island) ;
Rowe, C. (Department of Molecular Imaging & Therapy. Austin Health) ;
Chételat, G.. (Institut National de la Santé et de la Recherche Médicale (Inserm)) ;
Ruíz, A. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Marquié, M. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Chipi, E. (Section of Neurology. Center for Memory Disturbances - Lab. of Clinical Neurochemistry. Department of Medicine and Surgery. University of Perugia) ;
Wolfsgruber, S. (Department of Neurodegenerative Diseases and Psychiatry. University Hospital Bonn) ;
Heneka, M. (Department of Neurodegenerative Diseases and Psychiatry. University Hospital Bonn) ;
Boecker, H. (Functional Neuroimaging Group. Department of Radiology. University Hospital Bonn) ;
Peters, O. (Charité - Universitätsmedizin Berlin) ;
Jarholm, J. (Department of Neurology. Akershus University Hospital) ;
Rami, L. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Tort-Merino, A. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Binette, A.P. (Centre for Studies on Prevention of Alzheimer's Disease (StOP-AD) Centre) ;
Poirier, J. (Centre for Studies on Prevention of Alzheimer's Disease (StOP-AD) Centre) ;
Rosa-Neto, P. (Centre for Studies on Prevention of Alzheimer's Disease (StOP-AD) Centre) ;
Cerman, J. (International Clinical Research Center. St. Anne's University Hospital) ;
Dubois, B. (AP-HP. Hôpital de la Pitié Salpêtrière. Institute of Memory and Alzheimer's Disease (IM2A). Centre of excellence of neurodegenerative disease (CoEN). Department of Neurology) ;
Teichmann, M. (AP-HP. Hôpital de la Pitié Salpêtrière. Institute of Memory and Alzheimer's Disease (IM2A). Centre of excellence of neurodegenerative disease (CoEN). Department of Neurology) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Sánchez-Saudinós, María Belén (Institut d'Investigació Biomèdica Sant Pau) ;
Ebenau, J. (Alzheimer Center Amsterdam. Department of Neurology. Amsterdam Neuroscience. Amsterdam UMC. Vrije Universiteit Amsterdam) ;
Pocnet, C. (Old Age Psychiatry. University Hospital of Lausanne) ;
Eckerström, M. (Institute of Neuroscience and Physiology. Sahlgrenska Academy at University of Gothenburg) ;
Thompson, L. (Kingston. The University of Rhode Island) ;
Villemagne, V. (Department of Psychiatry. University of Pittsburgh) ;
Buckley, R. (Brigham and Women's Hospital and Department of Neurology Massachusetts General Hospital. Harvard Medical School) ;
Burnham, S. (Section of Neurology. Center for Memory Disturbances - Lab. of Clinical Neurochemistry. Department of Medicine and Surgery. University of Perugia) ;
Delarue, M. (Institut National de la Sant. et de la Recherche M.dicale (Inserm)) ;
Freund-Levi, Yvonne (Department of Neurobiology. Care Sciences and Society. Karolinska Institutet) ;
Wallin, Å.K. (Department of Clinical Sciences Malmö. Clinical Memory Research Unit. Lund University) ;
Ramakers, I. (Maastricht University. School for Mental Health and Neuroscience) ;
Tsolaki, Magda (Memory and Dementia Center. 3rd Department of Neurology. "G Papanicolau. " General Hospital. Aristotle University of Thessaloniki) ;
Soininen, H. (Institute of Clinical Medicine. Neurology. University of Eastern Finland) ;
Hampel, H. (GRC no 21. Alzheimer Precision Medicine (AMP). AP-HP. Pitié-Salpêtrière Hospital. Sorbonne University) ;
Spiru, L. (Geriatrics- Gerontology and Old Age Psychiatry. Alzheimer Unit. Ana Aslan International Foundation - Memory Center and Longevity Medicine) ;
Tijms, B. (Maastricht University. School for Mental Health and Neuroscience) ;
Ossenkoppele, R. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Verhey, F.R.J. (Maastricht University. School for Mental Health and Neuroscience) ;
Jessen, F. (German Center For Neurodegenerative Diseases/Clinical Research. Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE). Zentrum für klinische Forschung/AG) ;
Visser, P.J. (Department of Neurobiology. Care Sciences and Society. Karolinska Institutet)
Introduction: The evidence for characteristics of persons with subjective cognitive decline (SCD) associated with amyloid positivity is limited. Methods: In 1640 persons with SCD from 20 Amyloid Biomarker Study cohort, we investigated the associations of SCD-specific characteristics (informant confirmation, domain-specific complaints, concerns, feelings of worse performance) demographics, setting, apolipoprotein E gene (APOE) ε4 carriership, and neuropsychiatric symptoms with amyloid positivity. [...]
2022 - 10.1002/alz.12512
Alzheimer's & Dementia, Vol. 18 Núm. 10 (october 2022) , p. 1832-1845
|
|
visitant ::
identificació
alerta personal via correu electrònic o subscribiu-vos al 
canal RSS.
