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15 p, 7.1 MB Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method / Merlo-Mas, Josep (Nanomol Technologies S.L.) ; Tomsen-Melero, Judit (Institut de Ciència de Materials de Barcelona) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; González Mira, Elisabet (Institut de Ciència de Materials de Barcelona) ; Font, Albert (Leanbio S.L.) ; Pedersen, Jannik N. (Aarhus University. Department of Chemistry and Interdisciplinary Nanoscience Center (iNANO) (Denmark)) ; García Aranda, Natalia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cristóbal-Lecina, Edgar (Institut de Química Avançada de Catalunya) ; Alcaina-Hernando, Marta (Nanomol Technologies S.L.) ; Mendoza, Rosa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Garcia-Fruitos, Elena (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lizarraga, Teresa (Leanbio S.L.) ; Resch, Susanne (BioNanoNet Forschungsgesellschaft mbH (Austria)) ; Schimpel, Christa (BioNanoNet Forschungsgesellschaft mbH (Austria)) ; Falk, Andreas (BioNanoNet Forschungsgesellschaft mbH (Austria)) ; Pulido, Daniel (Institut de Química Avançada de Catalunya) ; Royo, Miriam (Institut de Química Avançada de Catalunya) ; Schwartz, Simó (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Abasolo, Ibane (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pedersen, Jan Skov (Aarhus University. Department of Chemistry and Interdisciplinary Nanoscience Center (iNANO) (Denmark)) ; Danino, Dganit (Technion - Israel Institute of Technology. CryoEM Laboratory of Soft Matter) ; Soldevila, Andreu (Leanbio S.L.) ; Veciana i Miró, Jaume (Institut de Ciència de Materials de Barcelona) ; Sala, Santi (Nanomol Technologies S.L.) ; Ventosa, Nora (Institut de Ciència de Materials de Barcelona) ; Córdoba, Alba (Nanomol Technologies S.L.)
Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads to cardiovascular, cerebrovascular, and renal disease, ultimately leading to death in the fourth or fifth decade of life. [...]
2021 - 10.1016/j.supflu.2021.105204
The Journal of Supercritical Fluids, Vol. 173 (July 2021) , art. 105204  

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