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21 p, 11.5 MB |
Identification of constrained sequence elements across 239 primate genomes
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Kuderna, Lukas F. K. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Ulirsch, Jacob C. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Rashid, Sabrina (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Ameen, Mohamed (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Sundaram, Laksshman (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Hickey, Glenn (University of California. Santa Cruz Genomics Institute) ;
Cox, Anthony J. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Gao, Hong (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Kumar, Arvind (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Aguet, Francois (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
Christmas, Matthew J. (Uppsala University. Department of Medical Biochemistry and Microbiology) ;
Clawson, Hiram (University of California. Santa Cruz Genomics Institute) ;
Haeussler, Maximilian (University of California. Santa Cruz Genomics Institu) ;
Janiak, Mareike C. (University of Salford. School of Science, Engineering and Environment) ;
Kuhlwilm, Martin (University of Vienna. Department of Evolutionary Anthropology) ;
Orkin, Joseph D. (Université de Montréal. Département d'Anthropologie) ;
Bataillon, Thomas (Aarhus University. Bioinformatics Research Centre) ;
Shivakumara Manu (Academy of Scientific and Innovative Research (Ghaziabad, Índia)) ;
Valenzuela, Alejandro (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ;
Bergman, Juraj (Aarhus University. Bioinformatics Research Centre) ;
Rouselle, Marjolaine (Aarhus University. Bioinformatics Research Centre) ;
Silva, Felipe Ennes (Mamirauá Institute for Sustainable Development) ;
Agueda Calpena, Lidia (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Blanc, Julie (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Gut, Marta (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
de Vries, Dorien (University of Salford. School of Science, Engineering and Environment) ;
Goodhead, Ian (University of Salford. School of Science, Engineering and Environment) ;
Harris, R. Alan (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Raveendran, Muthuswamy (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Jensen, Axel (Uppsala University. Department of Ecology and Genetics) ;
Chuma, Idriss S. (Tanzania National Parks) ;
Horvath, Julie E. (University of North Carolina at Chapel Hill. Renaissance Computing Institute) ;
Hvilsom, Christina (Copenhagen Zoo) ;
Juan, David (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ;
Frandsen, Peter (Copenhagen Zoo) ;
Schraiber, Joshua G. (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units)) ;
de Melo, Fabiano R. (Universidade Federal de Viçosa) ;
Bertuol, Fabrício (Universidade Federal do Amazonas. Departamento de Genética) ;
Byrne, Hazel (University of Utah. Department of Anthropology) ;
Sampaio, Iracilda (Universidade Federal do Pará (Brasil)) ;
Pires Farias, Izeni (Universidade Federal do Amazonas. Departamento de Genética) ;
Valsecchi, João (Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica-ComFauna) ;
Messias, Malu (Universidade Federal de Rondônia) ;
da Silva, Maria N. F. (Instituto Nacional de Pesquisas da Amazônia) ;
Trivedi, Mihir (Centre for Cellular and Molecular Biology (Hyderabad, Índia)) ;
Rossi, Rogerio (Universidade Federal do Mato Grosso. Instituto de Biociências) ;
Hrbek, Tomas (Trinity University. Department of Biology) ;
Andriaholinirina, Nicole (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Rabarivola, Clément J. (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Zaramody, Alphonse (University of Mahajanga. Faculty of Science, Technology and Environment) ;
Jolly, Clifford J. (New York University .Department of Anthropology) ;
Phillips-Conroy, Jane (Washington University School of Medicine in St Louis. Department of Neuroscience) ;
Wilkerson, Gregory (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Abbee, C. (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Simmons, Joe H. (MD Anderson Cancer Center. Keeling Center for Comparative Medicine and Research) ;
Fernandez-Duque, Eduardo (Yale University. Department of Anthropology) ;
Kanthaswamy, Sree (University of California. California National Primate Research Center) ;
Shiferaw, Fekadu (The Carter Center Ethiopia) ;
Wu, Dong-Dong (Chinese Academy of Sciences. Kunming Institute of Zoology. State Key Laboratory of Genetic Resources and Evolution) ;
Zhou, Long (Zhejiang University School of Medicine. Center for Evolutionary and Organismal Biology) ;
Shao, Yong (Chinese Academy of Sciences. Kunming Institute of Zoology. State Key Laboratory of Genetic Resources and Evolution) ;
Zhang, Guojie (Zhejiang University Medical Center) ;
Keyyu, Julius D. (Tanzania Wildlife Research Institute) ;
Knauf, Sascha (Justus Liebig University. Faculty of Veterinary Medicine) ;
Le, Minh D. (Vietnam National University. Department of Environmental Ecology) ;
Lizano, Esther (Institut Català de Paleontologia Miquel Crusafont) ;
Merker, Stefan epartment of Environmental Ecology (State Museum of Natural History Stuttgart. Department of Zoology) ;
Navarro, Arcadi, 1969- (Universitat Pompeu Fabra. Institut de Biologia Evolutiva) ;
Nadler, Tilo (Cuc Phuong Commune) ;
Khor, Chiea Chuen (Genome Institute of Singapore) ;
Lee, Jessica (Mandai Nature) ;
Tan, Patrick (Duke-NUS Medical School) ;
Lim, Weng Khong (SingHealth Duke-NUS Genomic Medicine Centre) ;
Kitchener, Andrew C. (School of Geosciences) ;
Zinner, Dietmar (Leibniz ScienceCampus Primate Cognition) ;
Gut, Ivo (Centre Nacional d'Anàlisi Genòmica (CNAG)) ;
Melin, Amanda D. (University of Calgary. Alberta Children's Hospital Research Institute) ;
Guschanski, Katerina (University of Edinburgh. School of Biological Sciences) ;
Schierup, Mikkel Heide (Aarhus University. Bioinformatics Research Centre) ;
Beck, Robin (University of Salford. School of Science, Engineering and Environment) ;
Karakikes, Ioannis (Stanford University. Department of Cardiothoracic Surgery) ;
Wang, Kevin C. (Veterans Affairs Palo Alto Healthcare System) ;
Umapathy, Govindhaswamy (Centre for Cellular and Molecular Biology (Hyderabad, Índia)) ;
Roos, Christian (Leibniz Institute for Primate Research. German Primate Center) ;
Boubli, Jean (University of Salford. School of Science, Engineering and Environment) ;
Siepel, Adam (Simons Center for Quantitative Biology. Cold Spring Harbor Laboratory) ;
Kundaje, Anshul (Stanford University. Department of Genetics) ;
Paten, Benedict (University of California. Santa Cruz Genomics Institute) ;
Lindblad-Toh, Kerstin (Uppsala University. Department of Medical Biochemistry and Microbiology) ;
Rogers, Jeffrey (Baylor College of Medicine. Department of Molecular and Human Genetics) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ;
Farh, Kyle Kai-How (Illumina. Co. Illumina Artificial Intelligence Laboratory (San Diego, Estats Units))
Noncoding DNA is central to our understanding of human gene regulation and complex diseases and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome. [...]
2023 -  10.1038/s41586-023-06798-8
Nature, Published online nov. 2023
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16 p, 3.6 MB |
The population genomic legacy of the second plague pandemic
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Gopalakrishnan, Shyam (University of Copenhagen. The GLOBE Institute) ;
Ebenesersdóttir, S. Sunna (University of Iceland. Department of Anthropology) ;
Lundstrøm, Inge K.C. (University of Copenhagen. The GLOBE Institute) ;
Turner-Walker, Gordon (National Yunlin University of Science & Technology (Taiwan)) ;
Moore, Kristjan H.S. (deCODE Genetics (Reykjavík, Islàndia)) ;
Luisi, Pierre (Universidad Nacional de Córdoba (Argentina)) ;
Margaryan, Ashot (University of Copenhagen. The GLOBE Institute) ;
Martin, Michael D. (Norwegian University of Science and Technology. NTNU University Museum) ;
Ellegaard, Martin Rene (Norwegian University of Science and Technology. NTNU University Museum) ;
Magnússon, Ólafur þ. (deCODE Genetics (Reykjavík, Islàndia)) ;
Sigurðsson, Ásgeir (deCODE Genetics (Reykjavík, Islàndia)) ;
Snorradóttir, Steinunn (deCODE Genetics (Reykjavík, Islàndia)) ;
Magnúsdóttir, Droplaug N. (deCODE Genetics (Reykjavík, Islàndia)) ;
Laffoon, Jason E. (Leiden University. Department of Archaeological Sciences) ;
van Dorp, Lucy (University College London. Department of Genetics, Evolution and Environment) ;
Liu, Xiaodong (University of Copenhagen. Department of Biology) ;
Moltke, Ida (University of Copenhagen. Department of Biology) ;
Ávila-Arcos, Maria C (Universidad Nacional Autónoma de México. Laboratorio Internacional de Investigación sobre el Genoma Humano) ;
Schraiber, Joshua G. (Illumina Inc. Illumina Artificial Intelligence Laboratory (USA)) ;
Rasmussen, Simon (University of Copenhagen. Novo Nordisk Foundation Center for Protein Research) ;
Juan, David (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Gelabert, Pere (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
de-Dios, Toni (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Fotakis, Anna K. (University of Copenhagen. The GLOBE Institute) ;
Iraeta-Orbegozo, Miren (University of Copenhagen. The GLOBE Institute) ;
Vågene, Åshild J. (Max Planck Institute for the Science of Human History) ;
Denham, Sean Dexter (University of Stavanger. Museum of Archaeology) ;
Christophersen, Axel (Norwegian University of Science and Technology. NTNU University Museum) ;
Stenøien, Hans K. (Norwegian University of Science and Technology. NTNU University Museum) ;
Garrett Vieira, Filipe (University of Copenhagen. The GLOBE Institute) ;
Liu, Shanlin (China National GeneBank) ;
Günther, Torsten (Evolutionsbiologisk Centrum EBC (Sweden)) ;
Kivisild, Toomas (University of Tartu. Institute of Genomics) ;
Moseng, Ole Georg (University of South-Eastern Norway. Department of Business, History and Social Sciences) ;
Skar, Birgitte (Norwegian University of Science and Technology. NTNU University Museum) ;
Cheung, Christina (Muséum National d'Histoire Naturelle (París, França)) ;
Sandoval-Velasco, Marcela (University of Copenhagen. The GLOBE Institute) ;
Wales, Nathan (University of York. Department of Archaeology) ;
Schroeder, Hannes (University of Copenhagen. The GLOBE Institute) ;
Campos, Paula F. (Universidade do Porto. Centro Interdisciplinar de Investigação Marinha e Ambiental) ;
Guðmundsdóttir, Valdís B. (University of Iceland. Department of Anthropology) ;
Sicheritz-Ponten, Thomas (AIMST University (Malàisia). Centre of Excellence for Omics-Driven Computational Biodiscovery) ;
Petersen, Bent (AIMST University (Malàisia). Centre of Excellence for Omics-Driven Computational Biodiscovery) ;
Halgunset, Jostein (Biobank1 (Norway)) ;
Gilbert, Edmund (School of Pharmacy and Biomolecular Sciences (Ireland)) ;
Cavalleri, Gianpiero L. (FutureNeuro SFI Research Centre (Ireland)) ;
Hovig, Eivind (University of Oslo. Center for Bioinformatics) ;
Kockum, Ingrid (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ;
Olsson, Tomas (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ;
Alfredsson, Lars (Karolinska Institutet (Estocolm, Suècia)) ;
Hansen, Thomas F. (Copenhagen Mental Health Services. Institute of Biological Psychiatry) ;
Werge, Thomas (Copenhagen Mental Health Services. Institute of Biological Psychiatry) ;
Willerslev, Eske (University of Cambridge. Department of Zoology) ;
Balloux, François (University College London. Department of Genetics, Evolution and Environment) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ;
Lalueza-Fox, Carles (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Nielsen, Rasmus (University of California. Department of Integrative Biology) ;
Stefánsson, Kári (deCODE Genetics (Reykjavík, Islàndia)) ;
Helgason, Agnar (deCODE Genetics (Reykjavík, Islàndia)) ;
Gilbert, M. Thomas P. (Norwegian University of Science and Technology. University Museum)
Human populations have been shaped by catastrophes that may have left long-lasting signatures in their genomes. One notable example is the second plague pandemic that entered Europe in ca. 1,347 CE and repeatedly returned for over 300 years, with typical village and town mortality estimated at 10%-40%. [...]
2022 - 10.1016/j.cub.2022.09.023
Current Biology, Vol. 32 (November 2022) , p. 1-9/e1-e6
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