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10 p, 1.0 MB Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes / Mishra, Rajashree (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Chesi, Alessandra (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Cousminer, Diana L. (Department of Genetics, Perelman School of Medicine, University of Pennsylvania) ; Hawa, Mohammad I. (Department of Immunobiology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London) ; Bradfield, Jonathan P. (Center for Applied Genomics, The Children's Hospital of Philadelphia) ; Hodge, Kenyaita M. (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Guy, Vanessa C. (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Hakonarson, Hakon (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Mauricio, Dídac (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Schloot, Nanette C. (German Diabetes Center, Düsseldorf) ; Yderstræde, Knud B. (Odense University Hospital) ; Voight, Benjamin F. (Department of Genetics, Perelman School of Medicine, University of Pennsylvania) ; Schwartz, Stanley (Main Line Health System, Wynnewood, PA, USA.) ; Boehm, Bernhard O. (Department of Internal Medicine I. Ulm University Medical Centre) ; Leslie, Richard David (Department of Immunobiology. Barts and the London School of Medicine and Dentistry, Queen Mary University of London) ; Grant, Struan F. A. (Division of Human Genetics. The Children's Hospital of Philadelphia) ;
Background: In adulthood, autoimmune diabetes can present as non-insulin-requiring diabetes, termed as 'latent autoimmune diabetes in adults' (LADA). In this study, we investigated established type 1 diabetes (T1D) and type 2 diabetes (T2D) genetic loci in a large cohort of LADA cases to assess where LADA is situated relative to these two well-characterized, classic forms of diabetes. [...]
2017
BMC Medicine, Vol. 15 Núm. 88 (2017) , p. 1-10  

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