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1.
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11 p, 1.1 MB |
Immune responses following neonatal vaccination with conserved F4 fragment of VtaA proteins from virulent Glaesserella parasuis adjuvanted with CAF®01 or CDA
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López-Serrano, Sergi (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Mahmmod, Yasser S. (Al Ain Men's College. Section of Veterinary Sciences) ;
Christensen, Dennis (Statens Serum Institut. Department of Infectious Disease Immunology) ;
Ebensen, Thomas (Helmholtz Centre for Infection Research. Department of Vaccinology and Applied Microbiology) ;
Guzmán, Carlos A. (Helmholtz Centre for Infection Research. Department of Vaccinology and Applied Microbiology) ;
Rodríguez Rey, Fernando (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Aragon, Virginia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Glaesserella parasuis is a Gram-negative bacterium that colonizes the upper airways of swine, capable of causing a systemic infection called Glässer's disease. This disease is more frequent in young post-weaning piglets. [...]
2023 -  10.1016/j.jvacx.2023.100330
Vaccine: X, Vol. 14 (june 2023)
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2.
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25 p, 2.7 MB |
Preclinical evaluation of PHH-1V vaccine candidate against SARS-CoV-2 in non-human primates
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Prenafeta, Antoni (HIPRA) ;
Bech-Sàbat, Gregori (HIPRA) ;
Moros, Alexandra (HIPRA) ;
Barreiro, Antonio (HIPRA) ;
Fernández, Alex (HIPRA) ;
Cañete, Manuel (HIPRA) ;
Roca, Mercè (HIPRA) ;
González-González, Luis (HIPRA) ;
Garriga, Carme (HIPRA) ;
Confais, Joachim (Cynbiose) ;
Toussenot, Marion (Cynbiose) ;
Contamin, Hugues (Cynbiose) ;
Pizzorno, Andrés (Université de Lyon. Centre International de Recherche en Infectiologie) ;
Rosa-Calatrava, Manuel (Université de Lyon) ;
Pradenas, Edwards (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Marfil, Sílvia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Universitat de Vic - Central de Catalunya) ;
Rica, Paula Cebollada (Universitat Pompeu Fabra) ;
Sisteré-Oró, Marta (Universitat Pompeu Fabra) ;
Meyerhans, Andreas (Institució Catalana de Recerca i Estudis Avançats) ;
Lorca, Cristina (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Prat, Teresa (HIPRA) ;
March, Ricard (HIPRA) ;
Ferrer, Laura (HIPRA)
SARS-CoV-2 emerged in December 2019 and quickly spread worldwide, continuously striking with an unpredictable evolution. Despite the success in vaccine production and mass vaccination programs, the situation is not still completely controlled, and therefore accessible second-generation vaccines are required to mitigate the pandemic. [...]
2023 - 10.1016/j.isci.2023.107224
iScience, Vol. 26 (june 2023)
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3.
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4.
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10 p, 2.0 MB |
A single, episodic event of unilateral/bilateral scrotal swelling in a group of adult boars at an Austrian boar stud
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Schwarz, Lukas (University of Veterinary Medicine Vienna. Department for Farm Animals and Veterinary Public Health) ;
Dürlinger, Sophie (University of Veterinary Medicine Vienna. Department for Farm Animals and Veterinary Public Health) ;
Martin, Vera (University of Veterinary Medicine Vienna. Department for Farm Animals and Veterinary Public Health) ;
Weißenböck, Herbert (University of Veterinary Medicine Vienna. Department of Pathobiology) ;
Brunthaler, Rene (University of Veterinary Medicine Vienna. Department of Pathobiology) ;
Rümenapf, Till (University of Veterinary Medicine Vienna. Department of Pathobiology) ;
Auer, Angelika (University of Veterinary Medicine Vienna. Department of Pathobiology) ;
Loncaric, Igor (University of Veterinary Medicine Vienna. Department of Pathobiology) ;
Zimpernik, Irene (Austrian Agency for Health and Food Safety) ;
Reisinger, Nicole (DSM Austria) ;
Behler-Wöchtl, Bettina (BIOMIN Research Center) ;
Scarlet, Dragos (University of Zurich. Clinic of Reproductive Medicine and Institute for Veterinary Anatomy) ;
Althouse, Gary (University of Pennsylvania. Department of Clinical Studies-New Bolton Center) ;
Kuster, Chris (Kuster Research and Consulting) ;
Kauffold, Johannes (University of Leipzig) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Laitat, Martine (University of Liège. Clinic for Swine) ;
Thilmant, Pierre (Centre d'Insémination Artificielle Porcin) ;
Grahofer, Alexander (University of Bern.Department for Clinical Veterinary Medicine) ;
Ladinig, Andrea (University of Veterinary Medicine Vienna. Department for Farm Animals and Veterinary Public Health)
Scrotal swelling is a clinical situation which can be caused by different aetiologies. In this case report, we describe a multi-week episode of unilateral and bilateral scrotal swelling in boars at an Austrian boar stud and its diagnostic work-up. [...]
2023 - 10.1186/s40813-023-00313-1
Porcine health management, Vol. 9 (july 2023)
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5.
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15 p, 6.0 MB |
Porcine Forebrain Vacuolization Associated with Wasting in Pigs : A Novel Pathological Outcome Associated with Vitamin-Mineral Deficiency?
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Ruiz-Riera, Elisa (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Vidal Barba, Enric (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Canturri, A. (University of Minnesota. Veterinary Diagnostic Laboratory) ;
Lehmbecker, Annika (University of Veterinary Medicine. Department of Pathology) ;
Cuvertoret-Sanz, Maria (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Lopez-Figueroa, Carlos (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Baumgärtner, W. (University of Veterinary Medicine. Department of Pathology) ;
Domingo, Mariano (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
The term wasting is a clinical name describing a physical condition characterized by growth retardation, usually of multifactorial origin. The present study describes an apparently new condition of pigs characterized clinically by wasting and pathologically by vacuolization of the brain. [...]
2023 - 10.3390/ani13142255
Animals, Vol. 13 (july 2023)
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6.
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9 p, 819.8 KB |
Inactivation of African swine fever virus inoculated in liquid plasma by spray drying and storage for 14 days at 4°C or 20°C
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Blázquez Salvador, Elena (APC Europe) ;
Pujols, Joan (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Navarro, Núria (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Rodríguez, Carmen (APC Europe) ;
Ródenas, Jesús (APC Europe) ;
Polo, Javier (APC LLC)
African swine fever virus (ASFV) is a dsDNA virus that can cause high mortality in pigs of all ages. Spray-dried porcine plasma (SDPP) is a highly digestible ingredient used in feed because it benefits performance, gut function and immunity. [...]
2023 - 10.1371/journal.pone.0290395
PloS one, Vol. 18 (august 2023)
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7.
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28 p, 4.0 MB |
Mycobacterium manresensis induces trained immunity in vitro
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de Homdedeu, Miquel (Hospital Universitari Vall d'Hebron) ;
Sanchez-Moral, Lidia (Institut Germans Trias i Pujol) ;
Violán, Concepció (Universitat Autònoma de Barcelona) ;
Ràfols, Neus (Institut Germans Trias i Pujol) ;
Ouchi, Dan (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Martín, Berta (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Peinado, Miguel A. (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Rodriguez-Cortes, Alheli (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Arch Sisquella, Marta (Institut Germans Trias i Pujol) ;
Perez-Zsolt, Daniel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Muñoz-Basagoiti, Jordana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Izquierdo Useros, Nuria (Centre for Biomedical Research on Infectious Diseases) ;
Salvador, Betlem (Jordi Gol University Research Institute in Primary Care) ;
Matllo, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
López-Serrano, Sergi (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Vilaplana, Cristina (Direcció Clínica Territorial de Malalties Infeccioses i Salut Internacional de Gerència Territorial Metropolitana Nord) ;
Torán-Montserrat, Pere (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Morros, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Monfà, Ramon (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Sarrias, Maria-Rosa (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
The COVID-19 pandemic posed a global health crisis, with new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants weakening vaccine-driven protection. Trained immunity could help tackle COVID-19 disease. [...]
2023 - 10.1016/j.isci.2023.106873
iScience, Vol. 26 (may 2023) , p. 106873
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8.
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19 p, 11.0 MB |
β-Cyclodextrins as affordable antivirals to treat coronavirus infection
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Raïch-Regué, Dalia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Tenorio, Raquel (Cell Structure Lab, Centro Nacional de Biotecnologia) ;
Fernández de Castro, Isabel (Cell Structure Lab, Centro Nacional de Biotecnologia) ;
Tarrés-Freixas, Ferran (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Sachse, Martin (Cell Structure Lab, Centro Nacional de Biotecnologia) ;
Perez-Zsolt, Daniel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Muñoz-Basagoiti, Jordana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Fernández-Sánchez, Sara Y. (Cell Structure Lab, Centro Nacional de Biotecnologia) ;
Gallemí, Marçal (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ortega-González, Paula (Cell Structure Lab, Centro Nacional de Biotecnologia) ;
Fernández-Oliva, Alberto (Cell Structure Lab, Centro Nacional de Biotecnologia) ;
Gabaldón, José A. (Universidad Católica San Antonio de Murcia. Reconocimiento y Encapsulación Molecular) ;
Nuñez-Delicado, Estrella (Universidad Católica San Antonio de Murcia. Reconocimiento y Encapsulación Molecular) ;
Casas, Josefina (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Roca, Núria (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Pérez, Mónica (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Usai, Carla (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Lorca-Oró, Cristina (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Vergara-Alert, Júlia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Instituto de Salud Carlos III. Consorcio Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ;
Clotet Sala, Bonaventura (Instituto de Salud Carlos III. Consorcio Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ;
Cerón-Carrasco, José P. (Universidad Politécnica de Cartagena. Centro Universitario de la Defensa) ;
Izquierdo Useros, Nuria (Instituto de Salud Carlos III. Consorcio Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ;
Risco, Cristina (Centro Nacional de Biotecnologia. Cell Structure Lab)
The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. Starting from a list of 116 drug candidates, we used molecular modelling tools to rank the 44 most promising inhibitors. [...]
2023 - 10.1016/j.biopha.2023.114997
Biomedicine & pharmacotherapy, Vol. 164 (june 2023) , p. 114997
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9.
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18 p, 10.4 MB |
Vaccination against swine influenza in pigs causes different drift evolutionary patterns upon swine influenza virus experimental infection and reduces the likelihood of genomic reassortments
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López-Valiñas, Álvaro (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Valle González, Marta (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Wang, Miaomiao (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Darji, Ayub (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Chiapponi, Chiara (Istituto Zooprofilattico Sperimentale della Lombardia ed Emilia-Romagna. WOAH Reference Laboratory for Swine Influenza) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Ganges, Llilianne (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Núñez, J. Ignacio (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Influenza A viruses (IAVs) can infect a wide variety of bird and mammal species. Their genome is characterized by 8 RNA single stranded segments. The low proofreading activity of their polymerases and the genomic reassortment between different IAVs subtypes allow them to continuously evolve, constituting a constant threat to human and animal health. [...]
2023 - 10.3389/fcimb.2023.1111143
Frontiers in cellular and infection microbiology, Vol. 13 (march 2023)
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8 p, 1.1 MB |
Monkeypox (Mpox) requires continued surveillance, vaccines, therapeutics and mitigating strategies
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Roper, Rachel L. (East Carolina University. Brody School of Medicine) ;
Garzino-Demo, Alfredo (University of Maryland School of Medicine) ;
Del Rio, Carlos (Emory University School of Medicine. Emory Center for AIDS Research) ;
Bréchot, Christian (University of South Florida School of Medicine) ;
Gallo, Robert (University of Maryland School of Medicine. Institute of Human Virology) ;
Hall, William (University College Dublin. Centre for Research in Infectious Diseases) ;
Esparza, José (University of Maryland School of Medicine) ;
Reitz, Marvin (University of Maryland School of Medicine) ;
Schinazi, Raymond F. (Emory University School of Medicine. Department of Pediatrics) ;
Parrington, Mark (Sanofi) ;
Tartaglia, James (Sanofi) ;
Koopmans, Marion (Erasmus University Medical Center) ;
Osorio, Jorge (University of Wisconsin-Madison. Global Health Institute) ;
Nitsche, Andreas (Robert Koch Institute. Center for Biological Threats and Special Pathogens) ;
Huan, Tan Boon (Nanyang Technological University. Lee Kong Chian School of Medicine) ;
LeDuc, James (University of Texas Medical Branch) ;
Gessain, Antoine (Université de Paris Cité. Institut Pasteur) ;
Weaver, Scott (University of Texas Medical Branch. Institute for Human Infections and Immunity) ;
Mahalingam, Suresh (Griffith University. Menzies Health Institute Queensland) ;
Abimiku, Alash'le (University of Maryland School of Medicine. Institute of Human Virology) ;
Vahlne, Anders (Karolinska Institutet (Estocolm, Suècia)) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Wang, Linfa (Duke-NUS Medical School. and Programme in Emerging Infectious Diseases) ;
Isaacs, Stuart N (University of Pennsylvania. Division of Infectious Diseases Perelman School) ;
Osterhaus, Albert (University of Veterinary Medicine Hannover. Center of Infection Medicine and Zoonosis Research) ;
Scheuermann, Richard H. (La Jolla Institute for Immunology. Center for Infectious Disease and Vaccine Research) ;
McFadden, Grant (Arizona State University. Biodesign Center for Immunotherapy, Vaccines and Virotherapy)
The widespread outbreak of the monkeypox virus (MPXV) recognized in 2022 poses new challenges for public healthcare systems worldwide. With more than 86,000 people infected, there is concern that MPXV may become endemic outside of its original geographical area leading to repeated human spillover infections or continue to be spread person-to-person. [...]
2023 - 10.1016/j.vaccine.2023.04.010
Vaccine, april 2023
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