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1.
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13 p, 1.6 MB |
Identification of Unique microRNA Profiles in Different Types of Idiopathic Inflammatory Myopathy
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Muñoz-Braceras, Sandra (National Institutes of Health (Estats Units d'Amèrica)) ;
Pinal-Fernandez, Iago (Johns Hopkins University School of Medicine) ;
Casal-Dominguez, Maria (Johns Hopkins University School of Medicine) ;
Pak, Katherine (National Institutes of Health (Estats Units d'Amèrica)) ;
Milisenda, José César (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Lu, Shajia (National Institutes of Health (Estats Units d'Amèrica)) ;
Gadina, Massimo (National Institutes of Health (Estats Units d'Amèrica)) ;
Naz, Faiza (National Institutes of Health (Estats Units d'Amèrica)) ;
Gutierrez-Cruz, Gustavo (National Institutes of Health (Estats Units d'Amèrica)) ;
Dell'Orso, Stefania (National Institutes of Health (Estats Units d'Amèrica)) ;
Torres-Ruiz, Jiram (Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mèxic)) ;
Grau-Junyent, Josep Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Paik, Julie J. (Johns Hopkins University School of Medicine) ;
Albayda, Jemima (Johns Hopkins University School of Medicine) ;
Christopher-Stine, Lisa (Johns Hopkins University School of Medicine) ;
Lloyd, Thomas E. (Johns Hopkins University School of Medicine) ;
Corse, Andrea (Johns Hopkins University School of Medicine) ;
Mammen, Andrew L. (Johns Hopkins University School of Medicine) ;
Universitat Autònoma de Barcelona
Dermatomyositis (DM), antisynthetase syndrome (AS), immune-mediated necrotizing myopathy (IMNM), and inclusion body myositis (IBM) are four major types of idiopathic inflammatory myopathy (IIM). Muscle biopsies from each type of IIM have unique transcriptomic profiles. [...]
2023 -  10.3390/cells12172198
Cells, Vol. 12 (september 2023)
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2.
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14 p, 2.8 MB |
Profiling of Myositis Specific Antibodies and Composite Scores as an Aid in the Differential Diagnosis of Autoimmune Myopathies
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Mahler, Michael (Research and Development, Inova Diagnostics, San Diego, CA 92131, USA; (K.M.); (A.S.); (C.B.)) ;
Malyavantham, Kishore (Research and Development, Inova Diagnostics, San Diego, CA 92131, USA; (K.M.); (A.S.); (C.B.)) ;
Seaman, Andrea (Research and Development, Inova Diagnostics, San Diego, CA 92131, USA; (K.M.); (A.S.); (C.B.)) ;
Bentow, Chelsea (Research and Development, Inova Diagnostics, San Diego, CA 92131, USA; (K.M.); (A.S.); (C.B.)) ;
Anunciación-Llunell, Ariadna (Hospital Universitari Vall d'Hebron) ;
Sanz-Martínez, María Teresa (Hospital Universitari Vall d'Hebron) ;
Viñas Gimenez, Laura (Hospital Universitari Vall d'Hebron) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona.
Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
(1) Background: Myositis specific antibodies (MSA) represent important diagnostic and stratification tools in idiopathic inflammatory myositis (IIM) patients. Here we aimed to evaluate the clinical performance of MSA profiled by a novel particle based multi-analyte technology (PMAT) in IIM and subsets thereof. [...]
2021 - 10.3390/diagnostics11122246
Diagnostics, Vol. 11 (november 2021)
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3.
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12 p, 2.8 MB |
COVID-19 Vaccination In Autoimmune Diseases (COVAD) Study : Vaccine Safety In Idiopathic Inflammatory Myopathies
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Gil-Vila, Albert (Hospital Universitari Vall d'Hebron) ;
Naveen, R. (Sanjay Gandhi Postgraduate Institute of Medical Sciences) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Sen, Parikshit (Maulana Azad Medical College) ;
Nune, Arvind (Southport and Ormskirk Hospital NHS Trust) ;
Gaur, Prithvi Sanjeevkumar (Smt. Kashibai Navale Medical and General Hospital) ;
Gonzalez, Raquel Arànega (Hospital Clínic i Provincial de Barcelona) ;
Lilleker, James B. (Northern Care Alliance NHS Foundation Trust) ;
Joshi, Mrudula (Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals) ;
Agarwal, Vishwesh (Mahatma Gandhi Mission Medical College) ;
Kardes, Sinan (Istanbul University) ;
Kim, Minchul (University of Illinois College of Medicine Peoria) ;
Day, Jessica (University of Melbourne) ;
Makol, Ashima (Mayo Clinic) ;
Milchert, Marcin (Pomeranian Medical University in Szczecin, ul Unii Lubelskiej 1) ;
Gheita, Tamer (Cairo University) ;
Salim, Babur (Fauji Foundation Hospital) ;
Velikova, Tsvetelina (Sofia University St. Kliment Ohridski) ;
Gracia-Ramos, Abraham Edgar (National Medical Center "La Raza") ;
Parodis, Ioannis (Örebro University) ;
Nikiphorou, Elena (King's College Hospital NHS Foundation Trust) ;
Tan, Ai Lyn (University of Leeds) ;
Chatterjee, Tulika (University of Illinois College of Medicine Peoria) ;
Cavagna, Lorenzo (Università degli studi di Pavia) ;
Saavedra, Miguel A. (Centro Médico Nacional La Raza) ;
Shinjo, Samuel Katsuyuki (Universidade de Sao Paulo) ;
Ziade, Nelly (Hotel-Dieu de France Hospital) ;
Knitza, Johannes (Universitätsklinikum Erlangen) ;
Kuwana, Masataka (Nippon Medical School Graduate School of Medicine) ;
Distler, Oliver (University Hospital Zurich (Suïssa)) ;
Chinoy, Hector (Salford Royal Hospital Northern Care Alliance NHS Foundation Trust) ;
Agarwal, Vikas (Sanjay Gandhi Postgraduate Institute of Medical Sciences) ;
Aggarwal, Rohit (University of Pittsburgh School of Medicine) ;
Gupta, Latika (The University of Manchester) ;
Universitat Autònoma de Barcelona
In this study we investigated COVID-19 vaccination-related adverse events (ADEs) 7 days postvaccination in patients with idiopathic inflammatory myopathies (IIMs) and other systemic autoimmune and inflammatory disorders (SAIDs). [...]
2022 - 10.1002/mus.27681
Muscle & nerve, july 2022
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4.
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8 p, 634.0 KB |
COVAD survey 2 long-term outcomes : unmet need and protocol
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Fazal, Zoha Zahid (Aga Khan University Hospital) ;
Sen, Parikshit (Maulana Azad Medical College) ;
Joshi, Mrudula (Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals) ;
Ravichandran, Naveen (Sanjay Gandhi Postgraduate Institute of Medical Sciences. Department of Clinical Immunology and Rheumatology) ;
Lilleker, James B. (Manchester Centre for Clinical Neurosciences) ;
Agarwal, Vishwesh (Mahatma Gandhi Mission Medical College) ;
Kardes, Sinan (Istanbul University. Department of Medical Ecology and Hydroclimatology) ;
Kim, Minchul (University of Illinois College of Medicine Peoria. Department of Internal Medicine) ;
Day, Jessica (University of Melbourne. Department of Medical Biology) ;
Makol, Ashima (Mayo Clinic. Division of Rheumatology) ;
Milchert, Marcin (Pomeranian Medical University in Szczecin. Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology) ;
Gheita, Tamer (Cairo University. Rheumatology Department) ;
Salim, Babur (Rheumatology Department, Fauji Foundation Hospital (Pakistan)) ;
Velikova, Tsvetelina (Sofia University St. Kliment Ohridski. Department of Clinical Immunology) ;
Gracia-Ramos, Abraham Edgar (Department of Internal Medicine, General Hospital, National Medical Center, La Raza (Mèxic)) ;
Parodis, Ioannis (Örebro University. Department of Rheumatology) ;
Nikiphorou, Elena (King's College Hospital NHS Foundation Trust) ;
Tan, Ai Lyn (University of Leeds. Leeds Institute of Rheumatic and Musculoskeletal Medicine) ;
Chatterjee, Tulika (University of Illinois College of Medicine Peoria. Department of Internal Medicine, Center for Outcomes Research) ;
Cavagna, Lorenzo (Università degli studi di Pavia. Dipartimento di Medicine Interna e Terapia Medica) ;
Saavedra, Miguel A. (Centro Médico Nacional La Raza (Mèxic)) ;
Shinjo, Samuel Katsuyuki (Universidade de Sao Paulo) ;
Ziade, Nelly (Hotel-Dieu de France Hospital. Rheumatology Department) ;
Nune, Arvind (Southport and Ormskirk Hospital NHS Trust) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Knitza, Johannes (Universitätsklinikum Erlangen) ;
Kuwana, Masataka (Nippon Medical School Graduate School of Medicine. Department of Allergy and Rheumatology) ;
Gutiérrez, Carlos-Enrique Toro (Pontifica Javeriana University) ;
Caballero-Uribe, Carlo Vinicio (Department of Medicine, Hospital Universidad del Norte) ;
Dey, Dzifa (University of Ghana School of Medicine and Dentistry. Department of Medicine and Therapeutics) ;
Distler, Oliver (University of Zurich. Department of Rheumatology) ;
Chinoy, Hector (Salford Royal Hospital. Department of Rheumatology) ;
Agarwal, Vikas (Sanjay Gandhi Postgraduate Institute of Medical Sciences. Department of Clinical Immunology and Rheumatology) ;
Aggarwal, Rohit (University of Pittsburgh School of Medicine) ;
Gupta, Latika (City Hospital, Sandwell and West Birmingham Hospitals NHS Trust) ;
Universitat Autònoma de Barcelona
The online version contains supplementary material available at 10. 1007/s00296-022-05157-6.
2022 - 10.1007/s00296-022-05157-6
Rheumatology International, august 2022, p. 1-8
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5.
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11 p, 2.5 MB |
Gastrointestinal Involvement in Dermatomyositis
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Matas-Garcia, Ana (Hospital Clínic i Provincial de Barcelona) ;
Milisenda, José César (Hospital Clínic i Provincial de Barcelona) ;
Espinosa, Gerard (Hospital Clínic i Provincial de Barcelona) ;
Cuatrecasas, Miriam (Hospital Clínic i Provincial de Barcelona) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Grau, Josep María (Hospital Clínic i Provincial de Barcelona) ;
Prieto-González, Sergio (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Dermatomyositis is a systemic vasculopathy mainly affecting skin, muscle and lung, but may affect the gastrointestinal tract. We aim to describe clinical characteristics of patients with severe gastrointestinal involvement related to dermatomyositis in our center and medical literature. [...]
2022 - 10.3390/diagnostics12051200
Diagnostics, Vol. 12 (may 2022)
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6.
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10 p, 1.3 MB |
Coordinated local RNA overexpression of complement induced by interferon gamma in myositis
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Casal-Dominguez, Maria (Johns Hopkins University School of Medicine) ;
Pinal-Fernandez, Iago (Johns Hopkins University School of Medicine) ;
Pak, Katherine (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Muñoz-Braceras, Sandra (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Milisenda, Jose C. (Hospital Clínic i Provincial de Barcelona) ;
Torres-Ruiz, Jiram (Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ;
Dell'Orso, Stefania (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Naz, Faiza (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Gutierrez-Cruz, Gustavo (National Institute of Arthritis and Musculoskeletal and Skin Diseases) ;
Duque-Jaimez, Yaiza (Hospital Clínic i Provincial de Barcelona) ;
Matas-Garcia, Ana (Hospital Clínic i Provincial de Barcelona) ;
Valls-Roca, Laura (Hospital Clínic i Provincial de Barcelona) ;
Garrabou, Glòria (Hospital Clínic i Provincial de Barcelona) ;
Trallero-Araguas, Ernesto (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Walitt, Brian (National Institute of Neurological Disorders and Stroke) ;
Christopher-Stine, Lisa (Johns Hopkins University School of Medicine) ;
Lloyd, Thomas E. (Johns Hopkins University School of Medicine) ;
Paik, Julie J. (Johns Hopkins University School of Medicine) ;
Albayda, Jemima (Johns Hopkins University School of Medicine) ;
Corse, Andrea (Johns Hopkins University School of Medicine) ;
Grau, Josep Maria (Hospital Clínic i Provincial de Barcelona) ;
Selva O'Callaghan, Albert (Universitat Autònoma de Barcelona) ;
Mammen, Andrew L. (Johns Hopkins University School of Medicine)
Complement proteins are deposited in the muscles of patients with myositis. However, the local expression and regulation of complement genes within myositis muscle have not been well characterized. In this study, bulk RNA sequencing (RNAseq) analyses of muscle biopsy specimens revealed that complement genes are locally overexpressed and correlate with markers of myositis disease activity, including the expression of interferon-gamma (IFN γ)-induced genes. [...]
2023 - 10.1038/s41598-023-28838-z
Scientific reports, Vol. 13 (february 2023)
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12 p, 661.0 KB |
COVID-19 severity and vaccine breakthrough infections in idiopathic inflammatory myopathies, other systemic autoimmune and inflammatory diseases, and healthy controls : a multicenter cross-sectional study from the COVID-19 Vaccination in Autoimmune Diseases (COVAD) survey
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Hoff, Leonardo Santos (Universidade Potiguar (Brasil)) ;
Ravichandran, Naveen (Sanjay Gandhi Postgraduate Institute of Medical Sciences) ;
Shinjo, Samuel Katsuyuki (Universidade de Sao Paulo) ;
Day, Jessica (University of Melbourne) ;
Sen, Parikshit (Maulana Azad Medical College) ;
Junior, Jucier Gonçalves (Universidade de Sao Paulo) ;
Lilleker, James B. (Northern Care Alliance NHS Foundation Trust) ;
Joshi, Mrudula (Byramjee Jeejeebhoy Government Medical College) ;
Agarwal, Vishwesh (Mahatma Gandhi Mission Medical College) ;
Kardes, Sinan (Istanbul University) ;
Kim, Minchul (University of Illinois College of Medicine. Center for Outcomes Research, Department of Internal Medicine) ;
Milchert, Marcin (Pomeranian Medical University in Szczecin) ;
Makol, Ashima (Mayo Clinic) ;
Gheita, Tamer (Cairo University) ;
Salim, Babur (Fauji Foundation Hospital) ;
Velikova, Tsvetelina (University Hospital "Lozenetz") ;
Gracia-Ramos, Abraham Edgar (General Hospital, National Medical Center, La Raza") ;
Parodis, Ioannis (Örebro University) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Nikiphorou, Elena (King's College Hospital NHS Foundation Trust) ;
Tan, Ai Lyn (University of Leeds) ;
Chatterjee, Tulika (University of Illinois College of Medicine) ;
Cavagna, Lorenzo (Università degli studi di Pavia) ;
Saavedra, Miguel A. (Centro Médico Nacional La Raza) ;
Ziade, Nelly (Hotel-Dieu de France Hospital) ;
Knitza, Johannes (Universitätsklinikum Erlangen) ;
Kuwana, Masataka (Nippon Medical School Graduate School of Medicine) ;
Nune, Arvind (Southport and Ormskirk Hospitals NHS Trust) ;
Distler, Oliver (University Hospital Zurich (Suïssa)) ;
Cansu, Döndü Üsküdar (Eskişehir Osmangazi University) ;
Traboco, Lisa (St Luke's Medical Center-Global City) ;
Wibowo, Suryo Angorro Kusumo (Universitas Indonesia) ;
Tehozol, Erick Adrian Zamora (Instituto Mexicano del Seguro Social Delegación Yucatán) ;
Serrano, Jorge Rojas (Instituto Nacional de Enfermedades Respiratorias) ;
La Torre, Ignacio García-De (Hospital General de Occidente and University of Guadalajara) ;
Wincup, Chris (University College London. Centre for Adolescent Rheumatology Versus Arthritis) ;
Pauling, John D. (North Bristol NHS Trust) ;
Chinoy, Hector (Salford Royal Hospital) ;
Agarwal, Vikas (Sanjay Gandhi Postgraduate Institute of Medical Sciences) ;
Aggarwal, Rohit (University of Pittsburgh School of Medicine) ;
Gupta, Latika (City Hospital, Sandwell and West Birmingham Hospitals NHS Trust) ;
Universitat Autònoma de Barcelona
We aimed to compare the spectrum and severity of COVID-19 and vaccine breakthrough infections (BIs) among patients with IIMs, other systemic autoimmune and inflammatory diseases (SAIDs), and healthy controls (HCs). [...]
2022 - 10.1007/s00296-022-05229-7
Rheumatology International, october 2022, p. 1-12
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9.
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5 p, 380.6 KB |
Anti-TIF-1γ Antibody Detection Using a Commercial Kit vs In-House Immunoblot : Usefulness in Clinical Practice
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Mariscal, Anaís (Institut d'Investigació Biomèdica Sant Pau) ;
Milán, Milena (Institut d'Investigació Biomèdica Sant Pau) ;
Baucells, Andrés (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez, Maria Angeles (Institut d'Investigació Biomèdica Sant Pau) ;
Garcia Guillen, Andrea (Institut d'Investigació Biomèdica Sant Pau) ;
Trallero-Araguás, Ernesto (Hospital Universitari Vall d'Hebron) ;
Alvarado, Marcelo (Hospital Universitari Vall d'Hebron) ;
Martinez-Martinez, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Alserawan, Leticia (Institut d'Investigació Biomèdica Sant Pau) ;
Franco-Leyva, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Sanz-Martínez, María Teresa (Hospital Universitari Vall d'Hebron) ;
Viñas-Giménez, Laura (Hospital Universitari Vall d'Hebron) ;
Corominas, Hèctor (Institut d'Investigació Biomèdica Sant Pau) ;
Juarez, Candido (Institut d'Investigació Biomèdica Sant Pau) ;
Castellvi, Ivan (Institut d'Investigació Biomèdica Sant Pau) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Anti-TIF-1γ autoantibody detection is important for cancer screening in patients with dermatomyositis. The gold standard for anti-TIF-1γ detection, immunoprecipitation, is only available from a few specialized laboratories worldwide, so commercial ELISA/immunoblot tests have emerged in recent years. [...]
2021 - 10.3389/fimmu.2020.625896
Frontiers in immunology, Vol. 11 (february 2021)
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10.
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7 p, 713.4 KB |
RIG-I expression in perifascicular myofibers is a reliable biomarker of dermatomyositis
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Suárez-Calvet, Xavier (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Gallardo, Eduard (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Pinal-Fernandez, Iago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Luna Salva, Noemí (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Lleixà, Cinta (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Diaz-Manera, Jordi (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Rojas-Garcia, Ricard (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Castellvi, Ivan (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez, M. Angeles (Institut d'Investigació Biomèdica Sant Pau) ;
Grau, Josep M. (Hospital Clínic i Provincial de Barcelona) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Illa, Isabel (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Universitat Autònoma de Barcelona
Dermatomyositis (DM) is inflammatory myopathy or myositis characterized by muscle weakness and skin manifestations. In the differential diagnosis of DM the evaluation of the muscle biopsy is of importance among other parameters. [...]
2017 - 10.1186/s13075-017-1383-0
Arthritis research & therapy, Vol. 19 (july 2017)
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