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Articles, 2 records found
Articles 2 records found  
1.
14 p, 4.0 MB Graphene Oxide Nanoscale Platform Enhances the Anti-Cancer Properties of Bortezomib in Glioblastoma Models / Sharp, Paul S. (University of Manchester. Nanomedicine Lab) ; Stylianou, Maria (University of Manchester. Nanomedicine Lab) ; Arellano, Luis M. (Institut Català de Nanociència i Nanotecnologia) ; Neves, Juliana C. (Institut Català de Nanociència i Nanotecnologia) ; Gravagnuolo, Alfredo M. (University of Manchester. Nanomedicine Lab) ; Dodd, Abbie (University of Manchester. Nanomedicine Lab) ; Barr, Katharine (University of Manchester. Nanomedicine Lab) ; Lozano, Neus (Institut Català de Nanociència i Nanotecnologia) ; Kisby, Thomas (University of Manchester. Nanomedicine Lab) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
Graphene-based 2D nanomaterials possess unique physicochemical characteristics which can be utilized in various biomedical applications, including the transport and presentation of chemotherapeutic agents. [...]
2023 - 10.1002/adhm.202201968
Advanced Healthcare Materials, Vol. 12, Issue 3 (January 2023) , art. 2201968  
Detailed record - Creative Commons
2.
15 p, 2.5 MB Deep tissue translocation of graphene oxide sheets in human glioblastoma 3D spheroids and an orthotopic xenograft model / de Lázaro, Irene (University of Manchester. Nanomedicine Lab) ; Sharp, Paul (University of Manchester. Nanomedicine Lab.) ; Gurcan, Cansu (Ankara University. Department of Biomedical Engineering) ; Ceylan, Ahmed (Ankara University. Faculty of Veterinary Medicine. Department of Histology Embryology) ; Stylianou, Maria (University of Manchester. Nanomedicine Lab.) ; Kisby, Thomas (University of Manchester. Nanomedicine Lab.) ; Chen, Yingxian (University of Manchester. Nanomedicine Lab.) ; Vranic, Sandra (University of Manchester. Nanomedicine Lab.) ; Barr, Katharine (University of Manchester. Nanomedicine Lab.) ; Taheri, Hadiseh (Ankara University. Department of Biomedical Engineering) ; Ozen, Asuman (Ankara University. Faculty of Veterinary Medicine. Department of Histology Embryology) ; Bussy, Cyrill (University of Manchester. Nanomedicine Lab.) ; Yilmazer, Acelya (Ankara University. Department of Biomedical Engineering) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
Its anatomical localization, a highly heterogeneous and drug-resistant tumor cell population and a "cold" immune microenvironment, all challenge the treatment of glioblastoma. Nanoscale drug delivery systems, including graphene oxide (GO) flakes, may circumvent some of these issues bypassing biological barriers, delivering multiple cargoes to impact several pathways simultaneously, or targeting the immune compartment. [...]
2021 - 10.1002/adtp.202000109
Advanced Therapeutics, Vol. 4, issue 1 (Jan. 2021) , art. 2000109  
Detailed record - Creative Commons

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