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Articles, 2 registres trobats
Articles 2 registres trobats  
1.
10 p, 497.8 KB The AT(N) framework for Alzheimer's disease in adults with Down syndrome / Rafii, Michael S. (University of Southern California) ; Ances, Beau M. (Washington University School of Medicine in St. Louis) ; Schupf, Nicole (Columbia University Medical Center) ; Krinsky-McHale, Sharon J. (NYS Institute for Basic Research in Developmental Disabilities) ; Mapstone, Mark (University of California) ; Silverman, Wayne (University of California) ; Lott, Ira (University of California) ; Klunk, Willian (University of Pittsburgh) ; Head, Elizabeth (University of California) ; Christian, Brad (University of Wisconsin Madison) ; Lai, Florence (Massachusetts General Hospital) ; Rosas, H.Diana (Harvard Medical School) ; Zaman, Shahid (Cambridgeshire and Peterborough NHS Foundation Trust) ; Petersen, Melissa E. (University of North Texas Health Science Center) ; Strydom, Andre (King's College London) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Handen, Benjamin (University of Pittsburgh) ; O'Bryant, Sid (University of North Texas Health Science Center) ; Universitat Autònoma de Barcelona
The National Institute on Aging in conjunction with the Alzheimer's Association (NIA-AA) recently proposed a biological framework for defining the Alzheimer's disease (AD) continuum. This new framework is based upon the key AD biomarkers (amyloid, tau, neurodegeneration, AT[N]) instead of clinical symptoms and represents the latest understanding that the pathological processes underlying AD begin decades before the manifestation of symptoms. [...]
2020 - 10.1002/dad2.12062
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 12 Núm. 1 (2020) , p. e12062  
2.
16 p, 930.6 KB Assessing general cognitive and adaptive abilities in adults with Down syndrome : a systematic review / Hamburg, Sarah (The London Down Syndrome Consortium (LonDownS), London, UK) ; Lowe, Bryony (Loughborough University. Department of Psychology) ; Startin, Carla Marie (The London Down Syndrome Consortium (LonDownS), London, UK) ; Padilla, Concepción (Department of Psychiatry, Herchel Smith Building for Brain & Mind Sciences, Forvie Site, Robinson Way, Cambridge, CB2 0SZ UK) ; Coppus, Antonia (Radboud University Medical Center. Department of Primary and Community Care) ; Silverman, Wayne (University of California. Department of Pediatrics) ; Fortea, Juan (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Zaman, Shahid (Department of Psychiatry, Herchel Smith Building for Brain & Mind Sciences, Forvie Site, Robinson Way, Cambridge, CB2 0SZ UK) ; Head, Elizabeth (University of Kentucky. Sanders-Brown Center on Aging) ; Handen, Benjamin L. (University of Pittsburgh School of Medicine. Department of Psychiatry) ; Lott, Ira (University of California. Departments of Pediatrics and Neurology) ; Song, Weihong (The University of British Columbia. Townsend Family Laboratories, Department of Psychiatry) ; Strydom, André (The London Down Syndrome Consortium (LonDownS), London, UK)
NOUAB.
Measures of general cognitive and adaptive ability in adults with Down syndrome (DS) used by previous studies vary substantially. This review summarises the different ability measures used previously, focusing on tests of intelligence quotient (IQ) and adaptive behaviour (AB), and where possible examines floor effects and differences between DS subpopulations. [...]

2019 - 10.1186/s11689-019-9279-8
Journal of Neurodevelopmental Disorders, Vol. 11 (august 2019)  

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