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9 p, 1.6 MB R1 and r2 relaxivities of dendrons based on a oeg-dtpa architecture : Effect of Gd3+ placement and dendron functionalization / Fransen, Peter (Biomaterials and Nanomedicine. Biomedical Research Networking Center in Bioengineering) ; Pulido, Daniel (Parc Científic de Barcelona. Unitat de química combinatòria) ; Simón Gracia, Lorena (Biomaterials and Nanomedicine. Biomedical Research Networking Center in Bioengineering) ; Candiota Silveira, Ana Paula (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Albericio, Fernando (Universitat de Barcelona. Departament de Química Orgànica) ; Royo, Miriam (Parc Científic de Barcelona. Unitat de química combinatòria)
In magnetic resonance imaging, contrast agents are employed to enhance the signal intensity. However, current commercial contrast agents are hindered by a low relaxivity constant. Dendrimers can be employed to create higher molecular weight contrast agents which have an increased relaxivity due to a lower molecular rotation. [...]
2015 - 10.1155/2015/848020
Journal of Nanotechnology, Vol. 2015 (2015) , art. 848020  

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