Results overview: Found 4 records in 0.01 seconds.
Articles, 3 records found
Research literature, 1 records found
Articles 3 records found  
1.
24 p, 770.3 KB Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management / Ramiro, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Simats, Alba ; García-Berrocoso, Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Stroke is the fifth leading cause of death and the most frequent cause of disability worldwide. Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to diagnose stroke is still a major concern. [...]
2018 - 10.1177/1756286418789340
Therapeutic Advances in Neurological Disorders, Vol. 11 (august 2018)  
2.
30 p, 397.4 KB The IMPROVE Guidelines (Ischaemia Models : Procedural Refinements Of in Vivo Experiments) / Percie du Sert, Nathalie (National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), London, UK) ; Alfieri, Alessio (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ; Allan, Stuart M (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ; Carswell, Hilary VO (Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, UK) ; Deuchar, Graeme A (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Farr, Tracy D (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ; Flecknell, Paul (Comparative Biology Centre, Newcastle University, UK) ; Gallagher, Lindsay (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Gibson, Claire L (Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK) ; Haley, Michael J (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ; Macleod, Malcolm R (Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK) ; McColl, Barry W (The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK) ; McCabe, Christopher (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Morancho, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Moon, Lawrence DF (Wolfson Centre for Age-Related Diseases, King's College London, London, UK) ; O'Neill, Michael J (Eli Lilly and Co., Windlesham, Surrey, UK) ; Pérez de Puig, Isabel (Institut d'Investigacions Biomèdiques de Barcelona) ; Planas, Anna (Institut d'Investigacions Biomèdiques de Barcelona) ; Ragan, C Ian (NC3Rs Board, London, UK) ; Rosell, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roy, Lisa A (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Ryder, Kathryn O (Home Office, London, UK) ; Simats, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sena, Emily S (Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK) ; Sutherland, Brad A (School of Medicine, Faculty of Health, University of Tasmania, Hobart, Australia) ; Tricklebank, Mark D (Centre for Neuroimaging Sciences, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, UK) ; Trueman, Rebecca C (School of Life Sciences, University of Nottingham Medical School, Nottingham, UK) ; Whitfield, Lucy (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ; Wong, Raymond (Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK) ; Macrae, I Mhairi (Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow/Arum Biosciences, Glasgow, UK) ; Universitat Autònoma de Barcelona
Most in vivo models of ischaemic stroke target the middle cerebral artery and a spectrum of stroke severities, from mild to substantial, can be achieved. This review describes opportunities to improve the in vivo modelling of ischaemic stroke and animal welfare. [...]
2017 - 10.1177/0271678X17709185
Journal of Cerebral Blood Flow & Metabolism, Vol. 37 (august 2017) , p. 3488-3517  
3.
14 p, 2.2 MB Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats / Campos Martorell, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Simats, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernández Guillamón, María del Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rosell, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Montaner, Joan (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Although the beneficial effects of statins on stroke have been widely demonstrated both in experimental studies and in clinical trials, the aim of this study is to prepare and characterize a new liposomal delivery system that encapsulates simvastatin to improve its delivery into the brain. [...]
2016 - 10.2147/IJN.S107292
International Journal of Nanomedicine, Vol. 11 (June 2016) , p. 3035-3048  

Research literature 1 records found  
1.
258 p, 8.7 MB Potencial terapèutic de nous biomarcadors d'isquèmia cerebral / Simats Oriol, Alba ; Montaner, Joan, dir. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García Berrocoso, Teresa, dir. ; Vila Bover, Miquel, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
L'ictus isquèmic és una de les principals causes de mort i discapacitat arreu. Actualment, l'únic tractament efectiu és la teràpia de reperfusió, ja sigui a través del tractament intravenós amb l'activador tissular del plasminogen (rt-PA) o la retirada del clot mitjançant trombectomia mecànica intra-arterial. [...]
Ischemic stroke is one of the leading causes of death and disability worldwide. Currently, the only effective treatments are reperfusion therapies, via the intravenous administration of recombinant tissue plasminogen activator (rt-PA) or the mechanical removal of the thrombus with stent-retriever or aspiration devices. [...]

[Bellaterra] : Universitat Autònoma de Barcelona, 2018.  

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