Resultados globales: 2 registros encontrados en 0.02 segundos.
Artículos, Encontrados 2 registros
Artículos Encontrados 2 registros  
1.
12 p, 1.7 MB Ligand-dependent Hedgehog pathway activation in Rhabdomyosarcoma : the oncogenic role of the ligands / Almazán-Moga, A (Hospital Universitari Vall d'Hebron) ; Zarzosa, P (Hospital Universitari Vall d'Hebron) ; Molist, C (Hospital Universitari Vall d'Hebron) ; Velasco, Pablo (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública) ; Pyczek, J (Institute of Human Genetics, University of Goettingen) ; Simon-Keller, K (Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg) ; Giralt, I (Hospital Universitari Vall d'Hebron) ; Vidal, I (LHospital Universitari Vall d'Hebron) ; Navarro, N (Hospital Universitari Vall d'Hebron) ; Segura, M F (Hospital Universitari Vall d'Hebron) ; Soriano, A (Hospital Universitari Vall d'Hebron) ; Navarro, S (Universitat de València. Departament de Patologia) ; Tirado, O M (Institut d'Investigació Biomèdica de Bellvitge (IDIBELL)) ; Ferreres, J C (Hospital Universitari Vall d'Hebron) ; Santamaria, A (Hospital Universitari Vall d'Hebron) ; Rota, R (Ospedale Pediatrico Bambino Gesù, IRCCS) ; Hahn, H (Institute of Human Genetics, University of Goettingen) ; Sánchez de Toledo, J (Hospital Universitari Vall d'Hebron) ; Roma, J (Hospital Universitari Vall d'Hebron) ; Gallego, S (Hospital Universitari Vall d'Hebron)
Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children. The Hedgehog (HH) pathway is known to develop an oncogenic role in RMS. However, the molecular mechanism that drives activation of the pathway in RMS is not well understood. [...]
2017 - 10.1038/bjc.2017.305
British Journal of Cancer, Vol. 117 (09 2017) , p. 1314-1325  
2.
12 p, 5.0 MB Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient / Saxena, Abhishek (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Stevens, Jo (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Cetin,Hakan (Nuffield Department of Clinical Neurosciences, John Radcliffe University Hospital, Oxford) ; Koneczny, Inga (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Webster, Richard (Nuffield Department of Clinical Neurosciences, John Radcliffe University Hospital, Oxford) ; Lazaridis, Konstantinos (Hellenic Pasteur Institute) ; Tzartos, Socrates (Hellenic Pasteur Institute) ; Vrolix, Kathleen (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Nogales-Gadea, Gisela (Institut Germans Trias i Pujol. Recerca Neuromuscular i Neuropediàtrica) ; Machiels, Barbie (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Molenaar, Peter C. (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Damoiseaux, Jan (Central Diagnostic Laboratory, Maastricht University Medical Center) ; De Baets, Marc H. (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Simon-Keller, Katja (Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg) ; Marx, Alexander (Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg) ; Vincent, Angela (Nuffield Department of Clinical Neurosciences, John Radcliffe University Hospital, Oxford) ; Mario Losen (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Pilar Martinez-Martinez (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ;
We report here the sequence and functional characterization of a recombinantly expressed.
autoantibody (mAb 131) previously isolated from a myasthenia gravis patient by immortalization of thymic B cells using Epstein-Barr virus and TLR9 activation. The antibody is characterized by a high degree of somatic mutations as well as a 6 amino acid insertion within the VHCDR2. [...]

2017 - 10.1038/s41598-017-14350-8
Sientific reports, Vol. 7 (october 2017) , p. 1-12  

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1 Simon-Keller, Katja
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