Home > Search Results: Soares, Heloisa P.
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11 p, 927.9 KB A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer / Wainberg, Zev A. (David Geffen School of Medicina, UCLA (USA)) ; Alsina, Maria (Vall d'Hebron Institut d'Oncologia) ; Soares, Heloisa P. (Moffitt Cancer Center (USA)) ; Braña, Irene (Princess Margaret Cancer Centre (Canada)) ; Britten, Carolyn D. (Medical University of South Carolina (USA)) ; Del Conte, Gianluca (IRCCS Ospedale San Raffaele(Italy)) ; Ezeh, Patrick (Pfizer Oncology (USA)) ; Houk, Brett (Pfizer Oncology (USA)) ; Kern, Kenneth A. (Pfizer Oncology (USA)) ; Leong, Stephen (University of Colorado (USA)) ; Pathan, Nuzhat (Pfizer Oncology, 10646 Science Center Drive, San Diego, CA 92121 USA) ; Pierce, Kristen J. (Pfizer Oncology (USA)) ; Siu, Lillian L. (Princess Margaret Cancer Centre (Canada)) ; Vermette, Jennifer (Pfizer Oncology (USA)) ; Tabernero, Josep (Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
This phase I, four-arm, open-label study (NCT01347866) evaluated the PI3K/mTOR inhibitors PF-04691502 (arms A, B) and gedatolisib (PF-05212384; arms C, D) in combination with the MEK inhibitor PD-0325901 (arm A, D) or irinotecan (arm B, C) in patients with advanced solid tumors. [...]
2017 - 10.1007/s11523-017-0530-5
Targeted Oncology, Vol. 12, Issue 6 (December 2017) , p. 775-785  
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