Home > Search Results: Stridh, Pernilla
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Articles, 2 records found
Articles 2 records found  
1.
16 p, 3.3 MB Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis / Bernardo-Faura, Martí (Centre de Recerca en Agrigenòmica) ; Rinas, Melanie (Rwth Aachen University. Joint Research Center for Computational Biomedicine) ; Wirbel, Jakob (Rwth Aachen University. Joint Research Center for Computational Biomedicine) ; Pertsovskaya, Inna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Pliaka, Vicky (School of Mechanical Engineering, National Technical University of Athens) ; Messinis, Dimitris E. (ProtATonce) ; Vila, Gemma (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Sakellaropoulos, Theodore (National Technical University of Athens) ; Faigle, Wolfgang (University of Zurich) ; Stridh, Pernilla (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ; Behrens, Janina R. (Charité University Medicine Berlin. NeuroCure Clinical Research Center and Department of Neurology) ; Olsson, Tomas (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ; Martin, Roland (University Hospital Zurich (Suïssa)) ; Paul, Friedemann (Charité University Medicine Berlin. NeuroCure Clinical Research Center and Department of Neurology) ; Alexopoulos, Leonidas G. (ProtATonce) ; Villoslada, Pablo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Saez-Rodriguez, Julio (Heidelberg University Hospital (Alemanya))
Multiple sclerosis (MS) is a major health problem, leading to a significant disability and patient suffering. Although chronic activation of the immune system is a hallmark of the disease, its pathogenesis is poorly understood, while current treatments only ameliorate the disease and may produce severe side effects. [...]
2021 - 10.1186/s13073-021-00925-8
Genome Medicine, Vol. 13 (July 2021) , art. 117  
Detailed record - Creative Commons
2.
21 p, 2.1 MB Natural Polymorphisms in Tap2 Influence Negative Selection and CD4:CD8 Lineage Commitment in the Rat / Tuncel, Jonatan (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Haag, Sabrina (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Yau, Anthony C. (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Norin, Ulrika (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Baud, Amelie (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Lönnblom, Erik (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Maratou, Klio (Imperial College London) ; Ytterberg, A. Jimmy (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Ekman, Diana (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Thordardottir, Soley (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Johannesson, Martina (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Gillett, Alan (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Stridh, Pernilla (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Jagodic, Maja (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Olsson, Tomas (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Zubarev, Roman (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; Mott, Richard (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Aitman, Timothy J. (Imperial College London) ; Flint, Jonathan (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ; Holmdahl, Rikard (Karolinska Institutet (Estocolm, Suècia). Department of Medical Biochemistry and Biophysics) ; EURATRANS Consortium
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. [...]
2014 - 10.1371/journal.pgen.1004151
PLoS Genetics, Vol. 10 Issue 2 (February 2014) , p. e1004151  
Detailed record - Creative Commons

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