Resultats globals: 3 registres trobats en 0.01 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
14 p, 4.0 MB Graphene Oxide Nanoscale Platform Enhances the Anti-Cancer Properties of Bortezomib in Glioblastoma Models / Sharp, Paul S. (University of Manchester. Nanomedicine Lab) ; Stylianou, Maria (University of Manchester. Nanomedicine Lab) ; Arellano, Luis M. (Institut Català de Nanociència i Nanotecnologia) ; Neves, Juliana C. (Institut Català de Nanociència i Nanotecnologia) ; Gravagnuolo, Alfredo M. (University of Manchester. Nanomedicine Lab) ; Dodd, Abbie (University of Manchester. Nanomedicine Lab) ; Barr, Katharine (University of Manchester. Nanomedicine Lab) ; Lozano, Neus (Institut Català de Nanociència i Nanotecnologia) ; Kisby, Thomas (University of Manchester. Nanomedicine Lab) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
Graphene-based 2D nanomaterials possess unique physicochemical characteristics which can be utilized in various biomedical applications, including the transport and presentation of chemotherapeutic agents. [...]
2023 - 10.1002/adhm.202201968
Advanced Healthcare Materials, Vol. 12, Issue 3 (January 2023) , art. 2201968  
2.
22 p, 4.5 MB Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state / Kisby, Thomas (University of Manchester. Nanomedicine Lab) ; de Lázaro, Irene (University of Manchester. Nanomedicine Lab) ; Stylianou, Maria (University of Manchester. Nanomedicine Lab) ; Cossu, Giulio (University of Manchester. Division of Cell Matrix Biology and Regenerative Medicine) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
In contrast to mammals, lower vertebrates are capable of extraordinary myocardial regeneration thanks to the ability of their cardiomyocytes to undergo transient dedifferentiation and proliferation. Somatic cells can be temporarily reprogrammed to a proliferative, dedifferentiated state through forced expression of Oct3/4, Sox2, Klf4 and c-Myc (OSKM). [...]
2021 - 10.1371/journal.pone.0251054
PloS one, Vol. 16, Issue 5 (May 2021) , p. e0251054  
3.
15 p, 2.5 MB Deep tissue translocation of graphene oxide sheets in human glioblastoma 3D spheroids and an orthotopic xenograft model / de Lázaro, Irene (University of Manchester. Nanomedicine Lab) ; Sharp, Paul (University of Manchester. Nanomedicine Lab.) ; Gurcan, Cansu (Ankara University. Department of Biomedical Engineering) ; Ceylan, Ahmed (Ankara University. Faculty of Veterinary Medicine. Department of Histology Embryology) ; Stylianou, Maria (University of Manchester. Nanomedicine Lab.) ; Kisby, Thomas (University of Manchester. Nanomedicine Lab.) ; Chen, Yingxian (University of Manchester. Nanomedicine Lab.) ; Vranic, Sandra (University of Manchester. Nanomedicine Lab.) ; Barr, Katharine (University of Manchester. Nanomedicine Lab.) ; Taheri, Hadiseh (Ankara University. Department of Biomedical Engineering) ; Ozen, Asuman (Ankara University. Faculty of Veterinary Medicine. Department of Histology Embryology) ; Bussy, Cyrill (University of Manchester. Nanomedicine Lab.) ; Yilmazer, Acelya (Ankara University. Department of Biomedical Engineering) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
Its anatomical localization, a highly heterogeneous and drug-resistant tumor cell population and a "cold" immune microenvironment, all challenge the treatment of glioblastoma. Nanoscale drug delivery systems, including graphene oxide (GO) flakes, may circumvent some of these issues bypassing biological barriers, delivering multiple cargoes to impact several pathways simultaneously, or targeting the immune compartment. [...]
2021 - 10.1002/adtp.202000109
Advanced Therapeutics, Vol. 4, issue 1 (Jan. 2021) , art. 2000109  

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