Resultats globals: 8 registres trobats en 0.01 segons.
Articles, 8 registres trobats
Articles 8 registres trobats  
1.
23 p, 3.2 MB Genotypic and Phenotypic Characterization of Staphylococcus aureus Isolates from the Respiratory Tract in Mechanically-Ventilated Patients / Lacoma, Alicia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Laabei, Maisem (Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK) ; Sánchez-Herrero, Jose Francisco (Institut Germans Trias i Pujol) ; Young, Bernadette (Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK) ; Godoy-Tena, Gerard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gomes Fernandes, Meissiner (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sumoy, Lauro (Institut Germans Trias i Pujol) ; Plans, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Arméstar, Fernando (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Prat i Aymerich, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Staphylococcus aureus is a commensal and frequent colonizer of the upper respiratory tract. When mechanical ventilation disrupts natural defenses, S. aureus is frequently isolated from the lower airways, but distinguishing between colonization and infection is difficult. [...]
2021 - 10.3390/toxins13020122
Toxins, Vol. 13 (february 2021)  
2.
15 p, 1.7 MB Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications / Carrillo-Reixach, Juan (Institut Germans Trias i Pujol) ; Torrens, L. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Simón-Coma, Marina (Institut Germans Trias i Pujol) ; Royo, Laura (Institut Germans Trias i Pujol) ; Domingo-Sàbat, Montse (Institut Germans Trias i Pujol) ; Abril-Fornaguera, J. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Akers, N. (Department of Genetics and Genomic Sciences. The Icahn Institute for Genomics and Multiscale Biology. Icahn School of Medicine at Mount Sinai) ; Sala Llinas, Margarita (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ragull, Sonia (Institut Germans Trias i Pujol) ; Arnal, Magdalena (Institut Hospital del Mar d'Investigacions Mèdiques) ; Villalmanzo, Núria (Institut Germans Trias i Pujol) ; Cairo, S. (Instituto di Ricerca Pediatrica. Corso Stati Uniti 4) ; Villanueva, A. (Institut d'Investigació Biomèdica de Bellvitge) ; Kappler, R. (Department of Pediatric Surgery. Dr. von Hauner Children's Hospital. Ludwig-Maximilians-University Munich) ; Garrido-Portnou, Marta (Hospital Universitari Vall d'Hebron) ; Guerra, Laura (University Hospital La Paz. Pathology Department) ; Sábado, Constantino (Hospital Universitari Vall d'Hebron) ; Guillén, Ganriela (Hospital Universitari Vall d'Hebron) ; Mallo, Maria del Mar (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Piñeyro, David (Institut Germans Trias i Pujol) ; Vázquez-Vitali, María (Institut Germans Trias i Pujol) ; Kuchuk, O. (Mount Sinai Liver Cancer Program. Divisions of Liver Diseases. Tisch Cancer Institute. Icahn School of Medicine at Mount Sinai) ; Mateos, M.E. (Pediatric Oncology Unit. Department of Pediatrics. University Hospital Reina Sofía) ; Ramírez, G. (University Hospital Universitario Virgen del Rocío. Pediatric Oncology Department) ; Santamaría, M.L. (University Hospital La Paz. Pediatric Surgery Department) ; Mozo, Y. (University Hospital La Paz. Pediatric Oncology Department) ; Soriano, A. (Hospital Universitari Val d'Hebron. Institut de Recerca) ; Grotzer, M. (Department of Pediatric Oncology. University Children's Hospital Zurich. University of Zurich) ; Branchereau, S. (Bicêtre Hospital) ; de Andoin, N.G. (Pediatric Oncology. Hospital Universitario Donostia) ; López-Ibor, B. (Department of Pediatric Hematology and Oncology. HM Montepríncipe Hospital) ; López-Almaraz, R. (Pediatric Oncology and Hematology. Hospital Universitario Cruces) ; Salinas, J.A. (Division of Hematology-Oncology. Department of Pediatrics. Hospital Universitari Son Espases) ; Torres, B. (Medical Oncology Department. Pediatric Oncology Department. University Hospital La Fe) ; Hernández, F. (University Hospital La Paz. Pediatric Surgery Department) ; Uriz, J.J. (Pediatric Oncology. Hospital Universitario Donostia) ; Fabre, M. (Department of Pathology. Hôpital Universitaire Necker-Enfants Malades. Assistance Publique-Hôpitaux de Paris. Université Paris Descartes) ; Blanco, J. (Universitat de Vic - Universitat Central de Catalunya) ; Paris, C. (Stem Cell Transplant Unit. Hospital Luis Calvo Mackenna) ; Bajčiová, V. (Department of Pediatric Oncology. Childrens University Hospital Brno) ; Laureys, G. (Department of Pediatric Hematology. Oncology and Hematopoietic Stem Cell Transplantation. Ghent University Hospital) ; Masnou, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Clos, Ariadna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Belendez, C. (Hospital Gregorio Marañón (Madrid)) ; Guettier, C. (Bicêtre Hospital) ; Sumoy, Lauro (Institut Germans Trias i Pujol) ; Planas, Ramón (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Jordà, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Nonell, Lara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Czauderna, P. (Department of Surgery and Urology for Children and Adolescents. Medical University of Gdansk) ; Morland, B. (Department of Oncology. Birmingham Women's and Children's Hospital) ; Sia, D. (Mount Sinai Liver Cancer Program. Divisions of Liver Diseases. Tisch Cancer Institute. Icahn School of Medicine at Mount Sinai) ; Losic, B. (Icahn Institute for Data Science and Genomic Technology. Icahn School of Medicine at Mount Sinai) ; Buendia, M.A. (INSERM. UMR 1193. Paul-Brousse Hospital. Hepatobiliary Centre) ; Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ; Llovet, J.M. (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Armengol, Carolina (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Background & Aims: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the mechanisms of HB pathobiology and to identify new biomarkers and therapeutic targets in a move towards precision medicine for patients with advanced HB. [...]
2020 - 10.1016/j.jhep.2020.03.025
Journal of Hepatology, Vol. 73 Núm. 2 (august 2020) , p. 328-341  
3.
12 p, 2.3 MB A comprehensive custom panel design for routine hereditary cancer testing: preserving control, improving diagnostics and revealing a complex variation landscape / Castellanos, Elisabeth (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Gel, Bernat (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Rosas, Inma (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Tornero, Eva (Institut Català d'Oncologia) ; Santín, Sheila (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Velasco, Juan (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; del Valle, Jesús (Institut Català d'Oncologia) ; Perucho, Manuel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Navarro, Matilde (Institut Català d'Oncologia) ; Brunet, Joan (Institut Català d'Oncologia) ; Pineda, Marta (Institut Català d'Oncologia) ; Feliubadaló, Lidia (Institut Català d'Oncologia) ; Capellá, Gabriel (Institut Català d'Oncologia) ; Lázaro, Conxi (Institut Català d'Oncologia) ; Serra, Eduard (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer)
We wanted to implement an NGS strategy to globally analyze hereditary cancer with diagnostic quality while retaining the same degree of understanding and control we had in pre-NGS strategies. To do this, we developed the I2HCP panel, a custom bait library covering 122 hereditary cancer genes. [...]
2017 - 10.1038/srep39348
Scientific reports (Nature Publishing Group), 2017, p. 1-12  
4.
17 p, 2.9 MB Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway / Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Howells, Lynne (University of Leicester. Departament of Cancer Studies) ; James, Mark I. (University of Leicester. Departament of Cancer Studies) ; Iwuji, Chinenye (University of Leicester. Departament of Cancer Studies) ; Manzano, José Luis (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Bugés, Cristina (Institut Germans Trias i Pujol) ; Abad, Albert (Hospital Cima Sanitas (Barcelona)) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol)
Resistance to oxaliplatin (OXA) is a complex process affecting the outcomes of metastatic colorectal cancer (CRC) patients treated with this drug. De-regulation of the NF-κB signalling pathway has been proposed as an important mechanism involved in this phenomenon. [...]
2016 - 10.1038/srep24675
Scientific reports (Nature Publishing Group), Vol. 6 (April 2016)  
5.
22 p, 7.0 MB Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential / Qualai, Jamal (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Li, Lin-Xi (University of Arkansas for Medical Sciences) ; Cantero, Jon (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Tarrats, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Fernández Sanmartín, Marco Antonio (Institut Germans Trias i Pujol) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Rodolosse, Annie (Institute for Research in Biomedicine (IRB Barcelona)) ; McSorley, Stephen J. (University of California) ; Genescà Ferrer, Meritxell (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
CD11c is an α integrin classically employed to define myeloid dendritic cells. Although there is little information about CD11c expression on human T cells, mouse models have shown an association of CD11c expression with functionally relevant T cell subsets. [...]
2016 - 10.1371/journal.pone.0154253
PloS one, Vol. 11 Núm. 4 (April 2016)  
6.
21 p, 3.6 MB Adhesion Molecules Associated with Female Genital Tract Infection / Qualai, Jamal (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cantero, Jon (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Li, Lin Xi (University of Arkansas for Medical Sciences) ; Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cabré i Gelada, Eduard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Dern, Olga (Institut Català de la Salut. Centre d'Atenció Primària Sant Fèlix) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Requena, Gerard (Institut Germans Trias i Pujol) ; McSorley, Stephen J. (University of California. Center for Comparative Medicine) ; Genescà Ferrer, Meritxell (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
Efforts to develop vaccines that can elicit mucosal immune responses in the female genital tract against sexually transmitted infections have been hampered by an inability to measure immune responses in these tissues. [...]
2016 - 10.1371/journal.pone.0156605
PloS one, Vol. 11 Núm. 6 (Juny 2016)  
7.
11 p, 2.2 MB Cyclic AMP signaling restricts activation and promotes maturation and antioxidant defenses in astrocytes / Paco, Sònia (Universitat de Barcelona) ; Hummel, Manuela (Centre for Genomic Regulation (Barcelona, Catalunya)) ; Plá, Virginia (Universitat de Barcelona) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Aguado, Fernando (Universitat de Barcelona)
BACKGROUND: cAMP signaling produces dramatic changes in astrocyte morphology and physiology. However, its involvement in phenotype acquisition and the transcriptionally mediated mechanisms of action are largely unknown. [...]
2016 - 10.1186/s12864-016-2623-4
BMC genomics, Vol. 17, Núm. 304 (April 2016)  
8.
2 p, 156.4 KB Draft genome sequences of Mycobacterium setense type strain DSM-45070 and the nonpathogenic strain Manresensis, isolated from the bank of the Cardener river in Manresa, Catalonia, Spain / Rech, Gabriel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Vilaplana i Massaguer, Cristina (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Velasco, Juan (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Santín, Sheila (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Prat i Aymerich, Cristina, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Alcaide, Fernando (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Comas, Iñaki (CIBER de Epidemiología y Salud Pública (CIBERESP)) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
We present here the draft genome sequences of two Mycobacterium setense strains. One of them corresponds to the M. setense type strain DSM-45070, originally isolated from a patient with a posttraumatic chronic skin abscess. [...]
2015 - 10.1128/genomeA.01485-14
Genome announcements, Vol. 3, Issue 1 (Jan-Feb. 2015) , p. e01485-14  

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