Results overview: Found 6 records in 0.01 seconds.
Articles, 6 records found
Articles 6 records found  
1.
12 p, 2.3 MB A comprehensive custom panel design for routine hereditary cancer testing: preserving control, improving diagnostics and revealing a complex variation landscape / Castellanos, Elisabeth (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Gel, Bernat (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Rosas, Inma (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Tornero, Eva (Institut Català d'Oncologia) ; Santín, Sheila (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Velasco, Juan (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; del Valle, Jesús (Institut Català d'Oncologia) ; Perucho, Manuel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Germans Trias i Pujol) ; Navarro, Matilde (Institut Català d'Oncologia) ; Brunet, Joan (Institut Català d'Oncologia) ; Pineda, Marta (Institut Català d'Oncologia) ; Feliubadaló, Lidia (Institut Català d'Oncologia) ; Capellá, Gabriel (Institut Català d'Oncologia) ; Lázaro, Conxi (Institut Català d'Oncologia) ; Serra, Eduard (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer)
We wanted to implement an NGS strategy to globally analyze hereditary cancer with diagnostic quality while retaining the same degree of understanding and control we had in pre-NGS strategies. To do this, we developed the I2HCP panel, a custom bait library covering 122 hereditary cancer genes. [...]
2017 - 10.1038/srep39348
Scientific reports, 2017, p. 1-12  
2.
17 p, 2.9 MB Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway / Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Howells, Lynne (University of Leicester. Departament of Cancer Studies) ; James, Mark I. (University of Leicester. Departament of Cancer Studies) ; Iwuji, Chinenye (University of Leicester. Departament of Cancer Studies) ; Manzano, José Luis (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Bugés, Cristina (Institut Germans Trias i Pujol) ; Abad, Albert (Hospital Cima Sanitas (Barcelona)) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol)
Resistance to oxaliplatin (OXA) is a complex process affecting the outcomes of metastatic colorectal cancer (CRC) patients treated with this drug. De-regulation of the NF-κB signalling pathway has been proposed as an important mechanism involved in this phenomenon. [...]
2016 - 10.1038/srep24675
Scientific reports, Vol. 6 (April 2016)  
3.
22 p, 7.0 MB Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential / Qualai, Jamal (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Li, Lin-Xi (University of Arkansas for Medical Sciences) ; Cantero, Jon (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Tarrats, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Fernández Sanmartín, Marco Antonio (Institut Germans Trias i Pujol) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Rodolosse, Annie (Institute for Research in Biomedicine (IRB Barcelona)) ; McSorley, Stephen J. (University of California) ; Genescà, Meritxell (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
CD11c is an α integrin classically employed to define myeloid dendritic cells. Although there is little information about CD11c expression on human T cells, mouse models have shown an association of CD11c expression with functionally relevant T cell subsets. [...]
2016 - 10.1371/journal.pone.0154253
PloS one, Vol. 11 Núm. 4 (April 2016)  
4.
21 p, 3.6 MB Adhesion Molecules Associated with Female Genital Tract Infection / Qualai, Jamal (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cantero, Jon (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Li, Lin Xi (University of Arkansas for Medical Sciences) ; Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cabré, Eduard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Dern, Olga (Institut Català de la Salut. Centre d'Atenció Primària Sant Fèlix) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Requena, Gerard (Institut Germans Trias i Pujol) ; McSorley, Stephen J. (University of California. Center for Comparative Medicine) ; Genescà, Meritxell (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
Efforts to develop vaccines that can elicit mucosal immune responses in the female genital tract against sexually transmitted infections have been hampered by an inability to measure immune responses in these tissues. [...]
2016 - 10.1371/journal.pone.0156605
PloS one, Vol. 11 Núm. 6 (Juny 2016)  
5.
11 p, 2.2 MB Cyclic AMP signaling restricts activation and promotes maturation and antioxidant defenses in astrocytes / Paco, Sònia (Universitat de Barcelona) ; Hummel, Manuela (Centre for Genomic Regulation (Barcelona, Catalunya)) ; Plá, Virginia (Universitat de Barcelona) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Aguado, Fernando (Universitat de Barcelona)
BACKGROUND: cAMP signaling produces dramatic changes in astrocyte morphology and physiology. However, its involvement in phenotype acquisition and the transcriptionally mediated mechanisms of action are largely unknown. [...]
2016 - 10.1186/s12864-016-2623-4
BMC Genomics, Vol. 17, Núm. 304 (April 2016)  
6.
2 p, 156.4 KB Draft genome sequences of Mycobacterium setense type strain DSM-45070 and the nonpathogenic strain Manresensis, isolated from the bank of the Cardener river in Manresa, Catalonia, Spain / Rech, Gabriel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Vilaplana i Massaguer, Cristina (Universitat Autònoma de Barcelona. Departament de Genètica i Microbiologia) ; Velasco, Juan (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Santín, Sheila (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Prat i Aymerich, Cristina, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Alcaide, Fernando (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Comas, Iñaki (CIBER de Epidemiología y Salud Pública (CIBERESP)) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
We present here the draft genome sequences of two Mycobacterium setense strains. One of them corresponds to the M. setense type strain DSM-45070, originally isolated from a patient with a posttraumatic chronic skin abscess. [...]
2015 - 10.1128/genomeA.01485-14
Genome Announcements, Vol. 3, Issue 1 (Jan-Feb. 2015) , p. e01485-14  

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7 Sumoy, Lauro
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