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8 p, 1.5 MB AGGRESCAN3D (A3D) : server for prediction of aggregation properties of protein structures / Zambrano, Rafael (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Jamroz, Michal (Uniwersytet Warszawski) ; Szczasiuk, Agata (Uniwersytet Warszawski) ; Pujols Pujol, Jordi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Kmiecik, Sebastian (Uniwersytet Warszawski) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Protein aggregation underlies an increasing number of disorders and constitutes a major bottleneck in the development of therapeutic proteins. Our present understanding on the molecular determinants of protein aggregation has crystalized in a series of predictive algorithms to identify aggregation-prone sites. [...]
2015 - 10.1093/nar/gkv359
Nucleic acids research, Vol. 43 (2015) , Web Server issue W306-W313  
Detailed record - Creative Commons

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