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8 p, 533.0 KB |
Rationale and design of the hip fracture accelerated surgical treatment and care track (hip attack) trial : A protocol for an international randomised controlled trial evaluating early surgery for hip fracture patients
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Borges, Flavia K. (Population Health Research Institute) ;
Bhandari, Mohit (McMaster University (Canadà)) ;
Patel, Ameen (McMaster University (Canadà)) ;
Avram, Victoria (McMaster University (Canadà)) ;
Guerra-Farfán, Ernesto (Hospital Universitari Vall d'Hebron) ;
Sigamani, Alben (Narayana Health) ;
Umer, Masood (Aga Khan University) ;
Tiboni, Maria (McMaster University (Canadà)) ;
Adili, Anthony (McMaster University (Canadà)) ;
Neary, John (McMaster University (Canadà)) ;
Tandon, Vikas (McMaster University (Canadà)) ;
Sancheti, Parag K. (Sancheti Institute for Orthopaedics and Rehabilitation (Pune, Índia)) ;
Lawendy, AbdelRahman (London Health Sciences Centre) ;
Jenkinson, Richard (University of Toronto) ;
Ramokgopa, Mmampapatla (University of the Witwatersrand) ;
Biccard, Bruce M (University of Cape Town) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Wang, Chew Yin (University of Malaya) ;
Landoni, Giovanni (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Forget, Patrice (Universitair Ziekenhuis Brussel) ;
Popova, Ekaterine (Institut d'Investigació Biomèdica Sant Pau) ;
Wood, Gavin (Queen's University) ;
Nabi Nur, Aamer (Shifa International Hospital) ;
John, Bobby (Christian Medical College) ;
Ślȩczka, Pawel (SPZOZ) ;
Feibel, Robert J. (University of Ottawa) ;
Balaguer Castro, Mariano (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Deheshi, Benjamin (Sharif Surgical Oncology) ;
Winemaker, Mitchell (McMaster University (Canadà)) ;
De Beer, Justin (McMaster University (Canadà)) ;
Kolesar, Richard (McMaster University (Canadà)) ;
Teixidor Serra, Jordi (Hospital Universitari Vall d'Hebron) ;
Tomas-Hernandez, Jordi (Hospital Universitari Vall d'Hebron) ;
McGillion, Michael (McMaster University (Canadà)) ;
Shanthanna, Harsha (McMaster University (Canadà)) ;
Moppett, Iain (University of Nottingham) ;
Vincent, Jessica (Population Health Research Institute) ;
Pettit, Shirley (Population Health Research Institute) ;
Harvey, Valerie (Population Health Research Institute) ;
Gauthier, Leslie (Hamilton Health Sciences) ;
Alvarado, Kim (McMaster University (Canadà)) ;
Devereaux, P. J (McMaster University (Canadà)) ;
Universitat Autònoma de Barcelona
Introduction Annually, millions of adults suffer hip fractures. The mortality rate post a hip fracture is 7%-10% at 30 days and 10%-20% at 90 days. Observational data suggest that early surgery can improve these outcomes in hip fracture patients. [...]
2019 -  10.1136/bmjopen-2018-028537
BMJ open, Vol. 9 Núm. 4 (january 2019) , p. e028537
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12 p, 1.3 MB |
Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3) : a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery
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Marcucci, Maura (Population Health Research Institute) ;
Painter, Thomas W. (Department of Anaesthesia. Royal Adelaide Hospital) ;
Conen, David (Population Health Research Institute) ;
Leslie, Kate (Department of Critical Care Medicine. Melbourne Medical School. University of Melbourne) ;
Lomivorotov, Vladimir V. (Department of Anesthesiology and Intensive Care. Novosibirsk State University) ;
Sessler, Daniel (Department of Outcomes Research. Anesthesiology Institute. Cleveland Clinic) ;
Chan, Matthew T.V. (The Chinese University of Hong Kong) ;
Borges, Flavia K. (Population Health Research Institute) ;
Martinez-Zapata, Maria José (Institut d'Investigació Biomèdica Sant Pau) ;
Wang, C.Y. (Department of Anaesthesiology. Faculty of Medicine. University of Malaya) ;
Xavier, Denis (St. John's Medical College) ;
Ofori, Sandra N. (Population Health Research Institute) ;
Landoni, G. (School of Medicine. Vita-Salute San Raffaele University) ;
Efremov, S. (Saint Petersburg State University Hospital) ;
Kleinlugtenbelt, Y.V. (Department of Orthopedic and Trauma Surgery. Deventer Ziekenhuis) ;
Szczeklik, W. (Jagiellonian University Medical College. Center for Intensive Care and Perioperative Medicine) ;
Schmartz, D. (CHU Brugmann. Université libre de Bruxelles) ;
Garg, A. X. (Department of Medicine. Epidemiology and Biostatistics. Western University) ;
Short, T.G. (University of Auckland. School of Health Sciences) ;
Wittmann, M. (Department of Anesthesiology. University Hospital) ;
Meyhoff, C.S. (Department of Anaesthesia and Intensive Care. Bispebjerg and Frederiksberg Hospital. University of Copenhagen) ;
Amir, Mohammed (Shifa International Hospital (STMU)) ;
Torres, D. (Universidad de Los Andes) ;
Patel, A. (Department of Medicine. McMaster University) ;
Duceppe, E. (Department of Medicine. Universite de Montreal) ;
Ruetzler, K. (Department of Outcomes Research. Anesthesiology Institute. Cleveland Clinic) ;
Parlow, Joel (Department of Anesthesiology and Perioperative Medicine. Kingston General Hospital and Queen's University) ;
Tandon, V. (Department of Medicine. McMaster University) ;
Wang, M.K. (Population Health Research Institute) ;
Fleischmann, E. (Department of Anesthesia. General Intensive Care and Pain Management. Medical University of Vienna) ;
Polanczyk, C.A. (Cardiology Department. Hospital de Clínicas de Porto Alegre) ;
Jayaram, R. (Nuffield Department of Anaesthetics. Clinical Neurosciences. University of Oxford) ;
Astrakov, S.V. (Department of Anesthesiology. Novosibirsk State University) ;
Rao, M. (St. John's Medical College) ;
VanHelder, T. (Department of Anesthesia. McMaster University) ;
Wu, W.K.K. (The Chinese University of Hong Kong) ;
Cheong, C.C. (Department of Anaesthesiology. Faculty of Medicine. University of Malaya) ;
Ayad, S. (Case Western Reserve University. Anesthesiology Institute. Cleveland Clinic - Fairview Hospital) ;
Abubakirov, M. (Meshalkin National Medical Research Center) ;
Kirov, M. (Department of Anesthesiology and Intensive Care Medicine. Northern State Medical University) ;
Bhatt, Keyur (SIDS Hospital & Research Centre) ;
de Nadal, M. (Hospital Universitari Vall d'Hebron) ;
Likhvantsev, V. (M. Vladimirskiy Moscow Regional Clinical and Research Institute) ;
Paniagua, Pilar (Institut d'Investigació Biomèdica Sant Pau) ;
Aguado, H.J. (Trauma & Orthopaedic surgery department. Hospital Clínico Universitario) ;
McGillion, M. (School of Nursing. McMaster University) ;
Lamy, A. (Department of Surgery. McMaster University) ;
Whitlock, R.P. (Department of Surgery. McMaster University) ;
Roshanov, P. (Department of Medicine. London Health Sciences Centre) ;
Stillo, D. (Population Health Research Institute) ;
Copland, I. (Population Health Research Institute) ;
Vincent, J. (Population Health Research Institute) ;
Balasubramanian, K. (Population Health Research Institute) ;
Bangdiwala, S.I. (Population Health Research Institute) ;
Biccard, Bruce M (Department of Anaesthesia and Perioperative Medicine. Groote Schuur Hospital and University of Cape Town) ;
Kurz, A. (Department of General Anaesthesiology. Emergency- and Intensive Care Medicine. Medical University Graz) ;
Srinathan, S. (Department of Surgery. University of Manitoba) ;
Petit, S. (Population Health Research Institute) ;
Eikelboom, J. (Population Health Research Institute) ;
Richards, T. (Faculty of Health and Medical Sciences. University of Western Australia) ;
Gross, P.L. (Department of Medicine. McMaster University) ;
Alfonsi, P. (Department of Anesthesiology. GH Paris Saint Joseph) ;
Guyatt, G. (Department of Medicine. McMaster University) ;
Belley-Cote, E. (Population Health Research Institute) ;
Spence, J. (Department of Anesthesia. McMaster University) ;
McIntyre, W. (Population Health Research Institute) ;
Yusuf, S. (Population Health Research Institute) ;
Devereaux, P. J (Population Health Research Institute)
Background: For patients undergoing noncardiac surgery, bleeding and hypotension are frequent and associated with increased mortality and cardiovascular complications. Tranexamic acid (TXA) is an antifibrinolytic agent with the potential to reduce surgical bleeding; however, there is uncertainty about its efficacy and safety in noncardiac surgery. [...]
2022 - 10.1186/s13063-021-05992-1
Trials, Vol. 23 Núm. 1 (december 2022) , p. 101
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9 p, 318.7 KB |
Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury : A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial
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Garg, Amit X. (London Health Sciences Centre) ;
Cuerden, Meaghan (London Health Sciences Centre) ;
Aguado, Hector (Hospital Clínico Universitario de Valladolid) ;
Amir, Mohammed (Shifa International Hospital) ;
Belley-Cote, Emilie P. (McMaster University (Canadà)) ;
Bhatt, Keyur (SIDS Hospital Research Centre) ;
Biccard, Bruce M (Groote Schuur Hospital) ;
Borges, Flavia K. (Population Health Research Institute) ;
Chan, Matthew (The Chinese University of Hong Kong) ;
Conen, David (Population Health Research Institute) ;
Duceppe, Emmanuelle (Population Health Research Institute) ;
Efremov, Sergey (Saint Petersburg State University) ;
Eikelboom, John (McMaster University (Canadà)) ;
Fleischmann, Edith (Medical University of Vienna) ;
Giovanni, Landoni (Istituto Scientifico Universitario San Raffaele) ;
Gross, Peter (McMaster University (Canadà)) ;
Jayaram, Raja (University of Oxford) ;
Kirov, Mikhail (Northern State Medical University of the Ministry of Healthcare of the Russian Federation) ;
Kleinlugtenbelt, Ydo (Deventer Ziekenhuis) ;
Kurz, Andrea (Medical University of Graz) ;
Lamy, Andre (Population Health Research Institute) ;
Leslie, Kate (The Royal Melbourne Hospital) ;
Likhvantsev, Valery (I. M. Sechenov Moscow Medical Academy) ;
Lomivorotov, Vladimir (Novosibirsk State University) ;
Marcucci, Maura (McMaster University (Canadà)) ;
Martinez-Zapata, Maria José (Institut d'Investigació Biomèdica Sant Pau) ;
McGillion, Michael (McMaster University (Canadà)) ;
McIntyre, William (Population Health Research Institute) ;
Meyhoff, Christian (University of Copenhagen) ;
Ofori, Sandra (Population Health Research Institute) ;
Painter, Thomas (Royal Adelaide Hospital) ;
Paniagua, Pilar (Institut d'Investigació Biomèdica Sant Pau) ;
Parikh, Chirag (Johns Hopkins University) ;
Parlow, Joel (Kingston General Hospital) ;
Patel, Ameen (McMaster University (Canadà)) ;
Polanczyk, Carisi (Hospital de Clinicas de Porto Alegre) ;
Richards, Toby (The University of Western Australia) ;
Roshanov, Pavel (Western University) ;
Schmartz, Denis (CHU Brugmann) ;
Sessler, Daniel (Cleveland Clinic) ;
Short, Tim (Auckland District Health Board) ;
Sontrop, Jessica M. (Western University) ;
Spence, Jessica (McMaster University (Canadà)) ;
Srinathan, Sadeesh (University of Manitoba) ;
Stillo, David (Population Health Research Institute) ;
Szczeklik, Wojciech (Jagiellonian University) ;
Tandon, Vikas (McMaster University (Canadà)) ;
Torres, David (Clinica Santa Maria (Chile)) ;
Van Helder, Thomas (Hamilton Health Sciences) ;
Vincent, Jessica (Population Health Research Institute) ;
Wang, C.Y. (University of Malaya) ;
Wang, Michael (McMaster University (Canadà)) ;
Whitlock, Richard (Population Health Research Institute) ;
Wittmann, Maria (Universitätsklinikum Bonn) ;
Xavier, Denis (St. John's National Academy of Health Sciences) ;
Devereaux, P. J (McMaster University (Canadà))
Background: Most patients who take antihypertensive medications continue taking them on the morning of surgery and during the perioperative period. However, growing evidence suggests this practice may contribute to perioperative hypotension and a higher risk of complications. [...]
2022 - 10.1177/20543581211069225
Canadian Journal of Kidney Health and Disease, Vol. 9 (january 2022)
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6 p, 356.0 KB |
Effects of accelerated versus standard care surgery on the risk of acute kidney injury in patients with a hip fracture : A substudy protocol of the hip fracture Accelerated surgical TreaTment and Care tracK (HIP ATTACK) international randomised controlled trial
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Kessler Borges, Flavia (Department of Perioperative Medicine. Population Health Research Institute (Ontario, Canadà)) ;
Devereaux, Philip James (Departments of Health Research Methods. Evidence. and Impact (HEI). McMaster University (Ontario, Canadà)) ;
Cuerden, Meaghan (Western University (Ontario, Canadà)) ;
Bhandari, Mohit (McMaster University (Ontario, Canadà)) ;
Guerra-Farfán, Ernesto (Hospital Universitari Vall d'Hebron) ;
Patel, Ameen (McMaster University (Ontario, Canadà)) ;
Sigamani, Alben (Clinical Research, Narayana Hrudayalaya Limited (Bangalore, Índia)) ;
Umer, Massod (Aga Khan University (Karachi, Pakistan)) ;
Neary, John (McMaster University (Ontario, Canadà)) ;
Tiboni, Maria (McMaster University (Ontario, Canadà)) ;
Tandon, Vikas (McMaster University (Ontario, Canadà)) ;
Ramokgopa, Mmampapatla Thomas (University of the Witwatersrand (Johannesburg, Sud-àfrica)) ;
Sancheti, Parag (Sancheti Institute for Orthopaedics and Rehabilitation (Pune, Índia)) ;
John, Bobby (Christian Medical College. Hospital Ludhiana (Ludhiana, Índia)) ;
Lawendy, AbdelRahman (Western University (Ontario, Canadà)) ;
Balaguer Castro, Mariano (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Jenkinson, Richard (Sunnybrook Health Sciences Centre (Ontario, Canadà)) ;
Ślȩczka, Pawel (Orthopaedic Department. SPZOZ (Myslenice, Polònia)) ;
Nabi Nur, Aamer (Shifa International Hospital (Islamabad, Pakistan)) ;
Wood, Gavin C. A. (Queen's University (Ontario, Canadà)) ;
Feibel, Robert (Division of Orthopaedic Surgery. University of Ottawa (Ontario, Canadà)) ;
McMahon, John Stephen (Markham Stouffville Hospital (Ontario, Canadà)) ;
Sigamani, Alen (Government TD Medical College (Allapuzha, Índia)) ;
Biccard, Bruce M (University of Cape Town (Rondebosch, Sud-àfrica)) ;
Landoni, Giovanni (Vita-Salute San Raffaele University (Milà, Itàlia)) ;
Szczeklik, Wojciech (Jagiellonian University. Medical College (Krakow, Polònia)) ;
Wang, Chew Yin (University Malaya (Kuala Lumpur, Malàisia)) ;
Tomas-Hernandez, Jordi (Hospital Universitari Vall d'Hebron) ;
Abraham, Valsa (Christian Medical College. Hospital Ludhiana (Ludhiana, Índia)) ;
Vincent, Jessica (Population Health Research Institute (Ontario, Canadà)) ;
Harvey, Valerie (Population Health Research Institute (Ontario, Canadà)) ;
Pettit, Shirley (Population Health Research Institute (Ontario, Canadà)) ;
Sontrop, Jessica M. (Western University (Ontario, Canadà)) ;
Garg, Amit (Western University (Ontario, Canadà)) ;
Universitat Autònoma de Barcelona
Introduction Inflammation, dehydration, hypotension and bleeding may all contribute to the development of acute kidney injury (AKI). Accelerated surgery after a hip fracture can decrease the exposure time to such contributors and may reduce the risk of AKI. [...]
2019 - 10.1136/bmjopen-2019-033150
BMJ open, Vol. 9 Núm. 9 (january 2019) , p. e033150
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