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Resultats globals: 3 registres trobats en 0.01 segons.
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Articles 3 registres trobats  
1.
9 p, 435.9 KB Prediction of overall survival in stage II and III colon cancer beyond TNM system : a retrospective, pooled biomarker study / Dienstmann, Rodrigo. (Hospital Universitari Vall d'Hebron) ; Mason, M. J. (Computational Oncology, Sage Bionetworks, Seattle, USA) ; Sinicrope, F. A. (Mayo Clinic and Mayo Comprehensive Cancer Center, Rochester, USA) ; Phipps, A. I. (Fred Hutchinson Cancer Research Center, Seattle, USA) ; Tejpar, Sabine (University Hospitals Gasthuisberg (Leuven, Bélgica)) ; Nesbakken, A. (Oslo University Hospital (Oslo, Noruega)) ; Danielsen, S. A. (Oslo University Hospital (Oslo, Noruega)) ; Sveen, A. (Oslo University Hospital (Oslo, Noruega)) ; Buchanan, Daniel D (The University of Melbourne) ; Clendenning, M. (The University of Melbourne) ; Rosty, C. (The University of Melbourne) ; Bot, Brian M (Computational Oncology, Sage Bionetworks, Seattle, USA) ; Alberts, S. R. (Mayo Clinic and Mayo Comprehensive Cancer Center, Rochester, USA) ; Milburn Jessup, J. (National Cancer Institute (Rockville, Estats Units d'Amèrica)) ; Lothe, R. A. (Oslo University Hospital (Oslo, Noruega)) ; Delorenzi, Mauro (SIB Swiss Institute Bioinformatics, Lausanne, Switzerland) ; Newcomb, P. A. (Fred Hutchinson Cancer Research Center, Seattle, USA) ; Sargent, D. (Mayo Clinic, Rochester, USA) ; Guinney, J. (Computational Oncology, Sage Bionetworks, Seattle, USA) ; Universitat Autònoma de Barcelona
TNM staging alone does not accurately predict outcome in colon cancer (CC) patients who may be eligible for adjuvant chemotherapy. It is unknown to what extent the molecular markers microsatellite instability (MSI) and mutations in BRAF or KRAS improve prognostic estimation in multivariable models that include detailed clinicopathological annotation. [...]
2017 - 10.1093/annonc/mdx052
Annals of oncology, Vol. 28 (february 2017) , p. 1023-1031  
Registre complet - Creative Commons
2.
33 p, 1.9 MB The Consensus Molecular Subtypes of Colorectal Cancer / Guinney, Justin (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Dienstmann, Rodrigo (Vall d'Hebron Institut d'Oncologia) ; Wang, Xin (City University of Hong Kong. Department of Biomedical Sciences (China)) ; de Reyniès, Aurélien (Ligue Nationale Contre le Cancer (France)) ; Schlicker, Andreas (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Soneson, Charlotte (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Marisa, Laetitia (Ligue Nationale Contre le Cancer (France)) ; Roepman, Paul (Agendia NV (Netherlands)) ; Nyamundanda, Gift (The Institute of Cancer Research (UK)) ; Angelino, Paolo (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Bot, Brian M. (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Morris, Jeffrey S. (The University of Texas M.D. Anderson Cancer Center (USA)) ; Simon, Iris M. (Agendia NV (Netherlands)) ; Gerster, Sarah (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Fessler, Evelyn (University of Amsterdam (Netherlands)) ; de Sousa e Melo, Felipe (University of Amsterdam (Netherlands)) ; Missiaglia, Edoardo (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Ramay, Hena (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Barras, David (SIB Swiss Institute of Bioinformatics (Switzerland)) ; Homicsko, Krisztian (Ecole Polytechnique Federale de Lausanne (Switzerland)) ; Maru, Dipen (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ; Manyam, Ganiraju C. (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ; Broom, Bradley (The University of Texas M.D. Anderson Cancer Center, Houston (USA)) ; Boige, Valerie (Gustave Roussy, Villejuif (France)) ; Perez-Villamil, Beatriz (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Laderas, Ted (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Salazar, Ramon (Institut d'Investigació Biomèdica de Bellvitge) ; Gray, Joe W. (Oregon Health Sciences University (USA)) ; Hanahan, Douglas (Ecole Polytechnique Federale de Lausanne (Switzerland)) ; Tabernero, Josep (Vall d'Hebron Institut d'Oncologia) ; Bernards, Rene (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Friend, Stephen H. (Sage Bionetworks. Fred Hutchinson Cancer Research Center (USA)) ; Laurent-Puig, Pierre (Universite Paris Descartes (France)) ; Medema, Jan Paul (LEXOR, Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam (Netherlands)) ; Sadanandam, Anguraj (The Institute of Cancer Research (UK)) ; Wessels, Lodewyk (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Delorenzi, Mauro (University of Lausanne (Switzerland)) ; Kopetz, Scott (The University of Texas M.D. Anderson Cancer Center (USA)) ; Vermeulen, Louis (LEXOR, Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam (Netherlands)) ; Tejpar, Sabine (Universitair ziekenhuis Leuven (Belgium)) ; Universitat Autònoma de Barcelona
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression-based CRC classifications and facilitate clinical translation, we formed an international consortium dedicated to large-scale data sharing and analytics across expert groups. [...]
2015 - 10.1038/nm.3967
Nature Medicine, Vol. 21, Num. 11 (November 2015) , p. 1350-1356  
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3.
8 p, 207.5 KB Phase I study of FOLFIRI plus pimasertib as second-line treatment for KRAS -mutated metastatic colorectal cancer / Macarulla Mercadé, Teresa (Vall d'Hebron Institut d'Oncologia) ; Cervantes, Andrés (Universitat de València. Biomedical Research Institute) ; Tabernero, Josep (Vall d'Hebron Institut d'Oncologia) ; Roselló, Susana (Universitat de València. Biomedical Research Institute) ; Van Cutsem, E. (University Hospitals Gasthuisberg (Leuven, Bélgica)) ; Tejpar, Sabine (University Hospitals Gasthuisberg (Leuven, Bélgica)) ; Prenen, H. (University Hospitals Gasthuisberg (Leuven, Bélgica)) ; Martinelli, E. (Second University of Naples. Department of Experimental and Clinical Medicine) ; Troiani, T. (Second University of Naples. Department of Experimental and Clinical Medicine) ; Laffranchi, B. (Merck Serono SA) ; Jego, V (Merck Serono SA) ; von Richter, O. (Merck KGaA) ; Ciardiello, Fortunato (Second University of Naples. Department of Experimental and Clinical Medicine) ; Universitat Autònoma de Barcelona
The mitogen-activated protein kinase (MAPK) pathway has been implicated in the molecular pathogenesis of human cancers, including metastatic colorectal cancer (mCRC). This provides a rationale for the development of MAPK-targeted agents such as pimasertib. [...]
2015 - 10.1038/bjc.2015.144
British Journal of Cancer, Vol. 112 (June 2015) , p. 1874-1881  
Registre complet - Creative Commons

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