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1.
135 p, 1.9 MB Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias : An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry / Lewczuk, Piotr (University Hospital of Białystok) ; Riederer, Peter (University Hospital Würzburg) ; O'Bryant, Sid E. (University of North Texas Health Science Center) ; Verbeek, Marcel M. (Radboud Alzheimer center) ; Dubois, Bruno (Salpêtrièrie Hospital) ; Visser, Pieter Jelle (Amsterdam Neuroscience VU University Medical Centre) ; Jellinger, Kurt A. (Institute of Clinical Neurobiology) ; Engelborghs, Sebastiaan (University Hospital Antwerp (Bèlgica)) ; Ramirez, Alfredo (University of Cologne) ; Parnetti, Lucilla (University of Perugia) ; Jack Jr, Clifford R. (Mayo Clinic) ; Teunissen, Charlotte E. (VU University Medical Center Amsterdam) ; Hampel, Harald (heimer (IM2A). Hôpital Pitié-Salpêtrière) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Jessen, Frank (German Center for Neurodegenerative Disorders (DZNE)) ; Glodzik, Lidia (NYU Langone Medical Center) ; de Leon, Mony J. (NYU Langone Medical Center) ; Fagan, Anne M. (Washington University School of Medicine) ; Molinuevo, José Luis (Hospital Clínic i Provincial de Barcelona) ; Jansen, Willemijn J. (Maastricht University) ; Winblad, Bengt (Karolinska Institutet (Estocolm, Suècia)) ; Shaw, Leslie M. (University of Pennsylvania) ; Andreasson, Ulf (The Sahlgrenska Academy at the University of Gothenburg) ; Otto, Markus (University of Ulm) ; Mollenhauer, Brit (Kassel and University Medical Center Göttingen) ; Wiltfang, Jens (University of Aveiro) ; Turner, Martin R. (University of Oxford) ; Zerr, Inga (German Center for Neurodegenerative Diseases) ; Handels, Ron (Karolinska Institutet (Estocolm, Suècia)) ; Thompson, Alexander G. (University of Oxford) ; Johansson, Gunilla (Karolinska Institutet (Estocolm, Suècia)) ; Ermann, Natalia (Universitätsklinikum Erlangen. and Friedrich-Alexander Universität Erlangen-Nürnberg) ; Trojanowski, John Q. (University of Pennsylvania) ; Karaca, Ilker (University of Bonn) ; Wagner, Holger (University of Bonn) ; Oeckl, Patrick (University of Ulm) ; van Waalwijk van Doorn, Linda (Radboud Alzheimer center) ; Bjerke, Maria (University of Antwerp) ; Kapogiannis, Dimitrios (National Institute on Aging/National Institutes of Health (NIA/NIH)) ; Kuiperij, H.Bea (Radboud Alzheimer center) ; Farotti, Lucia (University of Perugia) ; Li, Yi (NYU Langone Medical Center) ; Gordon, Brian A. (Washington University School of Medicine) ; Epelbaum, Stéphane (Institut de la Mémoire et de la Maladie d'Alzheimer (IM2A)) ; Vos, Stephanie J.B. (Maastricht University) ; Klijn, Catharina J.M. (Radboud Alzheimer Center) ; Van Nostrand, William E. (Stony Brook University) ; Minguillon, Carolina (Fundació Pasqual Maragall) ; Schmitz, Matthias (University Medical School) ; Gallo, Carla (Universidad Peruana Cayetano Heredia) ; Lopez Mato, Andrea (Maimonides University) ; Thibaut, Florence (University Hospital Cochin-Site Tarnier 89 rue d'Assas) ; Lista, Simone (heimer (IM2A). Hôpital Pitié-Salpêtrière) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Kornhuber, Johannes (Universitätsklinikum Erlangen) ; Universitat Autònoma de Barcelona
In the 12 years since the publication of the first Consensus Paper of the WFSBP on biomarkers of neurodegenerative dementias, enormous advancement has taken place in the field, and the Task Force takes now the opportunity to extend and update the original paper. [...]
2018 - 10.1080/15622975.2017.1375556
World Journal of Biological Psychiatry, Vol. 19 Núm. 4 (19 2018) , p. 244-328  
2.
6 p, 731.5 KB A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood : Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort / Stamate, Daniel (University of London) ; Kim, Min (Steno Diabetes Center Copenhagen) ; Proitsi, Petroula (King's College London) ; Westwood, Sarah (University of Oxford) ; Baird, Alison (University of Oxford) ; Nevado-Holgado, Alejo (University of Oxford) ; Hye, Abdul (King's College London) ; Bos, Isabelle (Amsterdam UMC) ; Vos, Stephanie J.B. (Maastricht University) ; Vandenberghe, Rik (Amsterdam UMC) ; Teunissen, Charlotte E. (Amsterdam UMC. University Medical Center) ; Kate, Mara Ten (Amsterdam UMC. University Medical Center) ; Scheltens, Philip (Vrije Universiteit Amsterdam) ; Gabel, Silvy (Laboratory for Cognitive Neurology) ; Meersmans, Karen (Laboratory for Cognitive Neurology) ; Blin, Olivier (Aix-Marseille Université) ; Richardson, Jill (GlaxoSmithKline R&D) ; De Roeck, Ellen (University of Antwerp) ; Engelborghs, Sebastiaan (Vrije Universiteit Brussel (VUB)) ; Sleegers, Kristel (Center for Molecular Neurology. VIB) ; Bordet, Régis (University of Lille) ; Ramit, Lorena (Hospital Clínic i Provincial de Barcelona) ; Kettunen, Petronella (Sahlgrenska Academy at University of Gothenburg) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans (Maastricht University) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Peyratout, Gwendoline (Lausanne University Hospital) ; Tainta, Mikel (Fundacion CITA-alzheimer Fundazioa) ; Johannsen, Peter (Copenhagen University Hospital) ; Freund-Levi, Yvonne (Karolinska Institutet (Estocolm, Suècia)) ; Frölich, Lutz (University of Heidelberg) ; Dobricic, Valerija (University of Lübeck) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Molinuevo, José L. (Universitat Pompeu Fabra) ; Wallin, Anders (Sahlgrenska Academy at the University of Gothenburg) ; Popp, Julius (Geneva University Hospitals) ; Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ; Bertram, Lars (University of Oslo) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ; Streffer, Johannes (University of Antwerp) ; Visser, Pieter J. (Amsterdam UMC) ; Lovestone, Simon (Janssen-Cilag UK Ltd) ; Legido-Quigley, Cristina (King's College London) ; Universitat Autònoma de Barcelona
Machine learning (ML) may harbor the potential to capture the metabolic complexity in Alzheimer Disease (AD). Here we set out to test the performance of metabolites in blood to categorize AD when compared to CSF biomarkers. [...]
2019 - 10.1016/j.trci.2019.11.001
Alzheimer's & dementia, Vol. 5 (2019) , p. 933-938  
3.
11 p, 783.1 KB Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay / Shi, Liu (University of Oxford) ; Westwood, Sarah (University of Oxford) ; Baird, Alison L. (University of Oxford) ; Winchester, Laura (University of Oxford) ; Dobricic, Valerija (University of Lübeck) ; Kilpert, Fabian (University of Lübeck) ; Hong, Shengjun (University of Lübeck) ; Franke, Andre (Christian-Albrechts-University of Kiel) ; Hye, Abdul (King's College London) ; Ashton, Nicholas J. (South London and Maudsley NHS Foundation) ; Morgan, Angharad R. (Cardiff University) ; Bos, Isabelle (Maastricht University) ; Vos, Stephanie J.B. (Amsterdam UMC. University Medical Center) ; Buckley, Noel J (University of Oxford) ; Kate, Mara ten (Amsterdam UMC. University Medical Center) ; Scheltens, Philip (Amsterdam UMC. University Medical Center) ; Vandenberghe, Rik (University Hospitals Leuven (Bèlgica)) ; Gabel, Silvy (Laboratory for Cognitive Neurology) ; Meersmans, Karen (Laboratory for Cognitive Neurology) ; Engelborghs, Sebastiaan (VUB University Hospital Brussels (UZ Brussel)) ; De Roeck, Ellen E. (Institute Born-Bunge. University of Antwerp) ; Sleegers, Kristel (Center for Molecular Neurology. VIB) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Blin, Olivier (Aix-Marseille Université) ; Richardson, Jill C. (GlaxoSmithKline R&D) ; Bordet, Régis (University of Lille) ; Molinuevo, José L. (Hospital Clínic i Provincial de Barcelona) ; Rami, Lorena (Universitat Pompeu Fabra) ; Wallin, Anders (Sahlgrenska Academy at University of Gothenburg) ; Kettunen, Petronella (University of Oxford) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Verhey, Frans (Maastricht University) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Popp, Julius (Geneva University Hospitals) ; Peyratout, Gwendoline (Lausanne University Hospital) ; Martinez-Lage, Pablo (Fundación CITA-Alzhéimer Fundazioa) ; Tainta, Mikel (CITA-Alzheimer Foundation) ; Johannsen, Peter Copenhagen University Hospital ; Teunissen, Charlotte E. (Vrije Universiteit) ; Freund-Levi, Yvonne (King's College London) ; Frölich, Lutz (University of Heidelberg) ; Legido-Quigley, Cristina (Steno Diabetes Center) ; Barkhof, Frederik (UCL Institutes of Neurology and Healthcare Engineering) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ; Baker, Susan (Janssen R&D) ; Morgan, B.Paul (Cardiff University) ; Streffer, Johannes (Janssen R&D. LLC) ; Visser, Pieter Jelle (Karolinska Institutet (Estocolm, Suècia)) ; Bertram, Lars (University of Oslo) ; Lovestone, Simon (University of Oxford) ; Nevado-Holgado, Alejo (University of Oxford) ; Universitat Autònoma de Barcelona
Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. [...]
2019 - 10.1016/j.jalz.2019.06.4951
Alzheimer's & Dementia, Vol. 15 Núm. 11 (november 2019) , p. 1478-1488  
4.
12 p, 1.1 MB Inflammatory biomarkers in Alzheimer's disease plasma / Morgan, Angharad R. (Systems Immunity Research Institute and UK Dementia Research Institute Cardiff, Cardiff University (Regne Unit)) ; Touchard, Samuel (Systems Immunity Research Institute and UK Dementia Research Institute Cardiff, School of Medicine, Cardiff University (Regne Unit)) ; Leckey, Claire A. (Cardiff University (Regne Unit)) ; O'Hagan, Caroline (Cardiff University (Regne Unit)) ; Nevado-Holgado, Alejo (University of Oxford (Regne Unit)) ; Barkhof, Frederik (University College London) ; Bertram, Lars (Max Planck Institute for Molecular Genetics (Alemanya)) ; Blin, Olivier (Aix-Marseille University (França)) ; Bos, Isabelle (Maastricht University (Països Baixos)) ; Dobricic, Valerija (University of Lübeck (Alemanya)) ; Engelborghs, Sebastiaan (Institute Born-Bunge (Bèlgica)) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli (Brescia, Itàlia)) ; Froelich, Lutz (University of Heidelberg (Alemanya)) ; Gabel, Silvy (Laboratory for Cognitive Neurology (Leuven, Bèlgica)) ; Johannsen, Peter (Karolinska Institutet (Stockholm, Sweden)) ; Kettunen, Petronella (University of Gothenburg (Gothenburg, Suècia)) ; Kłoszewska, Iwona (Medical University of Lodz (Lodz, Poland)) ; Legido-Quigley, Cristina (Imperial College London) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Martinez-Lage, Pablo (Fundación CITA-Alzheimer Fundazioa (San Sebastian, Spain)) ; Mecocci, Patrizia (University of Perugia (Itàlia)) ; Meersmans, Karen (Laboratory for Cognitive Neurology (Bèlgica)) ; Molinuevo, José Luis (Universitat Pompeu Fabra) ; Peyratout, Gwendoline (Lausanne University Hospital (Suïssa)) ; Popp, Julius (Hopitaux Universitaires Geneve and Universite de Geneve (Suïssa)) ; Richardson, Jill (GlaxoSmithKline R&D (Regne Unit)) ; Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Scheltens, Philip (Vrije Universiteit (Països Baixos)) ; Streffer, Johannes (University of Antwerp) ; Soininen, Hikka (University of Eastern Finland) ; Tainta, Mikel (Fundación CITA Alzheimer (Sant Sebastià, País Basc)) ; Teunissen, Charlotte E (University Hospitals Leuven (Bèlgica)) ; Tsolaki, Magda (AHEPA University Hospital (Grècia)) ; Vandenberghe, Rik (Amsterdam University Medical Centers (Països Baixos)) ; Visser, Pieter Jelle (Maastricht University (Països Baixos)) ; Vos, Stephanie (Maastricht University (Països Baixos)) ; Wahlund, Lars Olof (Karolinska Institutet (Estocolm, Suècia)) ; Wallin, Anders (University of Gothenburg Sahlgrenska Academy) ; Westwood, Sarah (University of Oxford (Regne Unit)) ; Zetterberg, Henrik (UK Dementia Research Institute (Londres, Regne Unit)) ; Lovestone, Simon (University of Oxford (Regne Unit)) ; Morgan, B. Paul (Cardiff University (Regne Unit)) ; Bullmore, Edward (University of Cambridge (Regne Unit)) ; Bhatti, Junaid (University of Cambridge (Regne Unit)) ; Chamberlain, Samuel J. (University of Cambridge (Regne Unit)) ; Correia, Marta Morgado (University of Cambridge (Regne Unit)) ; Crofts, Anna L. (Université de Sherbrooke (Canadà)) ; Dickinson, Amber (Addenbroke's Hospital (Cambridge, Regne Unit)) ; Foster, Andy C. (Cambridgeshire and Peterborough NHS Foundation Trust (Regne Unit)) ; Kitzbichler, Manfred G. (University of Cambridge (Regne Unit)) ; Knight, Clare (Cambridgeshire and Peterborough NHS Foundation Trust (Regne Unit)) ; Lynall, Mary-Ellen (University of Cambridge (Regne Unit)) ; Maurice, Christina (University of Cambridge (Regne Unit)) ; O'Donnell, Ciara M. (University College London (Regne Unit)) ; Pointon, Linda J. (University of Cambridge (Regne Unit)) ; St George Hyslop, Peter (University of Cambridge (Regne Unit)) ; Turner, Lorinda (University of Cambridge (Regne Unit)) ; Vertes, Petra E. (University of Cambridge (Regne Unit)) ; Widmer, Barry (University of Cambridge (Regne Unit)) ; Williams, Guy (University of Cambridge (Regne Unit)) ; Cavanagh, Jonathan T. O. (Karolinska Institutet (Suècia)) ; Deith, Catherine (Southern General Hospital Glasgow (Escòcia)) ; Farmer, Scott (Bio Med Sciences Inc.(Galveston, Estats Units)) ; McClean, John (NHS Greater Glasgow and Clyde (Glasgow, Escòcia)) ; McColl, Alison (College of Medical, Veterinary & Life Sciences (Glasgow, Escòcia)) ; McPherson, Andrew (Addenbrooke's Hospital (Cambridge, Regne Unit)) ; Scouller, Paul (Addenbrooke's Hospital (Cambridge, Regne Unit)) ; Sutherland, Murray (NHS Greater Glasgow and Clyde (Glasgow, Escòcia)) ; Boddeke, Erik W.G.M. (Københavns UniversitetThe institution (Copenhaguen, Dinamarca)) ; Khan, Shahid (GlaxoSmithKline plc. (Regne Unit)) ; Murphy, Philip Stephen (GlaxoSmithKline plc. (Regne Unit)) ; Parker, Christine A. (Wellcome Trust (Londres, Regne Unit)) ; Patel, Jai (GlaxoSmithKline plc. (Regne Unit)) ; Jones, Declan (Janssen Pharmaceuticals (Titusville, Estats Units)) ; de Boer, Peter (Janssen Research & Development (Beerse, Bèlgica)) ; Kemp, John A. (KU Leuven- University Hospital Leuven (Bèlgica)) ; Drevets, Wayne Curtis (Janssen Research & Development (Beerse, Bèlgica)) ; Nye, Jeffrey S. (Janssen Research & Development (Beerse, Bèlgica)) ; Wittenberg, Gayle M. (Janssen Research & Development (Beerse, Bèlgica)) ; Isaac, John T.R. (Johnson & Johnson (Estats Units)) ; Bhattacharya, Anindya (Janssen Research & Development (Beerse, Bèlgica)) ; Carruthers, Niicholas L. (Janssen Research & Development (Beerse, Bèlgica)) ; Kolb, Hartmuth Christian (Janssen Research & Development (Beerse, Bèlgica)) ; Pariante, Carmine M. (King's College London (Regne Unit)) ; Turkheimer, Federico (King's College London (Regne Unit)) ; Barker, Gareth John (King's College London (Regne Unit)) ; Byrom, Heidi (King's College London (Regne Unit)) ; Cash, Diana (King's College London (Regne Unit)) ; Cattaneo, Annamaria (King's College London (Regne Unit)) ; Gee, Anthony (King's College London (Regne Unit)) ; Hastings, Caitlín N.M. (King's College London (Regne Unit)) ; Mariani, Nicole (King's College London (Regne Unit)) ; McLaughlin, Anna Patricia (King's College London (Regne Unit)) ; Mondelli, Valeria (King's College London (Regne Unit)) ; Nettis, Maria Antonietta (King's College London (Regne Unit)) ; Nikkheslat, Naghmeh (King's College London (Regne Unit)) ; Randall, Karen (King's College London (Regne Unit)) ; Sheridan, Hannah C. (King's College London (Regne Unit)) ; Simmons, Camilla (King's College London (Regne Unit)) ; Singh, Nisha (King's College London (Regne Unit)) ; Van Loo, Victoria (King's College London (Regne Unit)) ; Vicente-Rodríguez, Marta (King's College London (Regne Unit)) ; Wood, Tobias (King's College London (Regne Unit)) ; Worrell, Courtney (King's College London (Regne Unit)) ; Zajkowska, Zuzanna (King's College London (Regne Unit)) ; Plath, Niels (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Egebjerg, Jan (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Eriksson, Hans (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Gastambide, Francois (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Adams, Karen Husted (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Jeggo, Ross D. (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Thomsen, Christian (Aalborg Universitetshospital (Aalborg, Dinamarca)) ; Pederson, Jan Torleif (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Campbell, Brian M. (Lundbeck Research USA Inc. (Deerfield, Estats Units)) ; Möller, Thomas (Lundbeck Research USA Inc. (Deerfield, Estats Units)) ; Nelson, Bob (H. Lundbeck A/S (Copenhagen, Dinamarca)) ; Zorn, Stevin H. (Lundbeck Research USA Inc. (Deerfield, Estats Units)) ; O'Connor, Jason (University of Texas Hlth Sci Ctr San Antonio(Estats Units)) ; Attenburrow, Mary Jane (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ; Baird, Alison (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ; Benjamin, Jithen (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ; Clare, Stuart (John Radcliffe Hosp, Oxford Ctr Funct MRI Brain (Oxford, Anglaterra)) ; Cowen, Philip (University of Oxford (Anglaterra)) ; Huang, I-Shuo Wade (Kennedy Inst Rheumatol (Oxford, Anglaterra)) ; Hurley, Samuel A. (University of Wisconsin-Madison (Madison, Estats Units)) ; Jones, Helen (Warneford Hosp, NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ; Mada, Francisca (Neurosciences & Neurology) ; Nevado-Holgado, Alejo (University of Oxford (Anglaterra)) ; Oladejo, Akitayo (Metropolitan Hospital Center (New York, Estats Units)) ; Ribe, Elena (King's College London (Londres, Anglaterra)) ; Smith, Katy (Warneford Hospital. NIHR Oxford Cognit Hlth Clin Res Facil (Oxford, Anglaterra)) ; Vyas, Anviti (University of Oxford (Oxford, Anglaterra)) ; Hughes, Zoe (Praxis Precision Medicines (Cambridge, Regne Unit)) ; Balice-Gordon, Rita (Sanofi S.A. (Gentilly, França)) ; Duerr, James M. (Pfizer Inc.(New York, Estats Units)) ; Piro, Justin R. (Pfizer Inc.(New York, Estats Units)) ; Sporn, Jonathan (Gilgamesh Pharmaceut (New York, Estats Units)) ; Perry, V. Hugh (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ; Cleal, Madeleine (University of Portsmouth (Anglaterra)) ; Fryatt, Gemma (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ; Gomez-Nicola, Diego (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ; Mancuso, Renzo (University of Southampton (Anglaterra)) ; Reynolds, Richard (University of Southampton. Ctr Biol Sci (Hants, Anglaterra)) ; Harrison, Neil (University fo Sussex (Brighton, Anglaterra)) ; Cercignani, Mara (University fo Sussex (Brighton, Anglaterra)) ; Clarke, Charlotte L. (University of Sussex (Brighton, Regne Unit)) ; Hoskins, Elizabeth (Sussex Partnership NHS Foundation Trust (Worthing, Regne Unit)) ; Kohn, Charmaine (Sussex Partnership NHS Foundation Trust (Worthing, Regne Unit)) ; Murray, Rosemary (Addenbrooke's Hospital (Cambridge, Regne Unit)) ; Wilcock, Lauren (Sussex Partnership NHS Fdn Trust (Hove, Anglaterra)) ; Wlazly, Dominika (Brighton and Sussex University Hospitals NHS Trust (Sussex, Anglaterra)) ; Mount, Howard T.J. (University of Toronto (Toronto, Canadà)) ; Universitat Autònoma de Barcelona
Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. A hypothesis-led plasma biomarker search was conducted in the context of international multicenter studies. [...]
2019 - 10.1016/j.jalz.2019.03.007
Alzheimer's & Dementia, Vol. 15 Núm. 6 (june 2019) , p. 776-787  
5.
22 p, 1.4 MB Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers / Jansen, Iris (Vrije Universiteit Amsterdam) ; van der Lee, Sven J (Vrije Universiteit Amsterdam) ; Gomez-Fonseca, Duber (Washington University School of Medicine) ; De Rojas, Itziar (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Dalmasso, Maria Carolina (Neurosciences and Complex Systems Unit (ENyS). CONICET. Hospital El Cruce. National University A. Jauretche (UNAJ)) ; Grenier-Boley, Benjamin (Université de Lille) ; Zettergren, Anna (University of Gothenburg) ; Mishra, Aniket (Université de Bordeaux) ; Ali, Muhammad (Washington University School of Medicine) ; Andrade, Victor (University Hospital Bonn. Medical Faculty) ; Bellenguez, Céline (Université de Lille) ; Kleineidam, Luca (German Center for Neurodegenerative Diseases (DZNE)) ; Küçükali, Fahri (University of Antwerp. Department of Biomedical Sciences) ; Sung, Ju Sung (Washington University School of Medicine) ; Tesí, Niccolo (Vrije Universiteit Amsterdam) ; Vromen, Ellen (Amsterdam Neuroscience. Neurodegeneration) ; Wightman, Douglas P (Vrije Universiteit Amsterdam) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Alegret, Montserrat (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Alvarez, Ignacio (Fundació per a la Recerca Biomèdica i Social Mútua de Terrassa) ; Amouyel, Philippe (Université de Lille) ; Athanasiu, Lavinia (NORMENT Centre. Institute of Clinical Medicine. University of Oslo and Division of Mental Health) ; Bahrami, Shahram (NORMENT Centre. Institute of Clinical Medicine. University of Oslo and Division of Mental Health) ; Bailly, Henri (Université Paris Cité) ; Belbin, Olivia (Institut d'Investigació Biomèdica Sant Pau) ; Bergh, Sverre (Vestfold Hospital Trust) ; Bertram, Lars (University of Lübeck) ; Biessels, Geert Jan (UMC Utrecht Brain Center) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Blesa, Rafael (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Boland, Anne (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Buerger, K. (Institute for Stroke and Dementia Research (ISD). University Hospital. LMU Munich) ; Carracedo, Ángel (Fundación Pública Galega de Medicina Xenómica-CIBERER-IDIS) ; Cervera Carles, Laura (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Chene, Geneviève (Department of Neurology. CHU de Bordeaux) ; Claassen, Jurgen (Donders Center for Medical Neuroscience) ; Debette, Stephanie (University School of Medicine) ; Deleuze, Jean‑Francois (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; De Deyn, Peter Paul (University Medical Center Groningen. Department of Neurology and Alzheimer Center Groningen.) ; Diehl-Schmid, Janine (kbo-Inn-Salzach-Hospital) ; Djurovic, Srdjan (University of Bergen. Department of Clinical Science. NORMENT Centre.) ; Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Dufouil, Carole (Pôle de Santé Publique) ; Duron, Emmanuelle (Univerisité Paris-Saclay) ; Düzel, Emrah (Otto-von-Guericke University Magdeburg. Institute of Cognitive Neurology and Dementia Research) ; Fladby, Tormod (Akershus University Hospital. Department of Neurology.) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Frölich, Lutz (Medical Faculty Mannheim. Department of Geriatric Psychiatry. Central Institute of Mental Health.) ; García-González, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Garcia-Martinez, María (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Giegling, Ina (Medical University of Vienna) ; Goldhardt, Oliver (Technical University of Munich) ; Gobom, Johan (Sahlgrenska University Hospital (Suècia)) ; Grimmer, Timo (Technical University of Munich) ; Haapasalo, Annakaisa (University of Eastern Finland A.I. Virtanen Institute for Molecular Sciences) ; Hampel, Harald (Neurology Business Group. Eisai Inc) ; Hanon, Olivier (Service gériatrie. Centre Mémoire de Ressources et Recherches Ile de France-Broca. AP-HP. Hôpital Broca) ; Hausner, Lucrezia (Central Institute of Mental Health. Department of Geriatric Psychiatry) ; Heilmann-Heimbach, Stefanie (Institute of Human Genetics. University of Bonn. School of Medicine and University Hospital Bonn) ; Helisalmi, Seppo (University of Eastern Finland. Institute of Clinical Medicine) ; Heneka, Michael (German Center for Neurodegenerative Diseases (DZNE)) ; Hernández, Isabel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Herukka, Sanna‑Kaisa (University of Eastern Finland. Department of Neurology. Institute of Clinical Medicine) ; Holstege, Henne (Vrije Universiteit Amsterdam. Section Genomics of Neurodegenerative Diseases and Aging) ; Jarholm, Jonas (Akershus University Hospital. Department of Neurology.) ; Kern, Silke (Sahlgrenska University Hospital. Psychiatry. Cognition and Old Age Psychiatry Clinic) ; Knapskog, Anne‑Brita (Oslo University Hospital. Department of Geriatric Medicine) ; Koivisto, A.M. (Department of Neurology. Helsinki University Hospital) ; Kornhuber, Johannes (Friedrich-Alexander Universität Erlangen-Nürnberg) ; Kuulasmaa, Teemu (University of Eastern Finland) ; Lage, Carmen (University of California) ; Laske, Christoph (University of Tübingen. Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy.) ; Leinonen, Ville (Kuopio University Hospita. Department of Neurosurgery.) ; Lewczuk, Piotr (Medical University of Białystok. Department of Neurodegeneration Diagnostics.) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; López de Munain, Adolfo (University of The Basque Country) ; López-Garcia, Sara (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Maier, Wolfgang (University Hospital Bonn. Department of Neurodegenerative Diseases and Geriatric Psychiatry) ; Marquié, Marta (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Mol, Merel O. (Erasmus Medical Centre. Department of Neurology) ; Montrreal, Laura (Universitat Internacional de Catalunya. Ace Alzheimer Center Barcelona) ; Moreno, Fermin (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; Moreno-Grau, Sonia (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Nicolas, Gael (Normandie Univ. UNIROUEN. Department of Genetics and CNR-MAJ) ; Nöthen, Markus M. (Institute of Human Genetics. University of Bonn. School of Medicine and University Hospital Bonn) ; Orellana, Adelina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Pålhaugen, Lene (Akershus University Hospital. Department of Neurology) ; Papma, Janne M. (Erasmus MC University Medical Center. Department of Neurology and Alzheimer Center Erasmus MC) ; Pasquier, Florence (Université Lille) ; Perneczky, Robert (Imperial College London. Ageing Epidemiology Research Unit) ; Peters, Oliver (German Center for Neurodegenerative Diseases (DZNE)) ; Pijnenburg, Yolande A.L. (Amsterdam Neuroscience. Neurodegeneration) ; Popp, Julius (University Hospital of Lausanne. Department of Psychiatry) ; Posthuma, Danielle (Vrije Universiteit Amsterdam) ; Pozueta, Ana (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Priller, Josef (Technical University Munich. Department of Psychiatry and Psychotherapy) ; Puerta, Raquel (Universitat Internacional de Catalunya. Ace Alzheimer Center Barcelona) ; Quintela, Inés (Grupo de Medicina Xenómica. Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidade de Santiago de Compostela) ; Ramakers, Inez (Maastricht University. Department of Psychiatry and Neuropsychologie) ; Rodríguez-Rodríguez, Eloy (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Rujescu, Dan (Medical University of Vienna. Department of Psychiatry and Psychotherapy) ; Saltvedt, Ingvild (University Hospital of Trondheim. Department of Geriatrics) ; Sánchez-Juan, Pascual (Alzheimer's Centre Reina Sofia-CIEN Foundation-ISCIII) ; Scheltens, Philip (Amsterdam Neuroscience. Neurodegeneration) ; Scherbaum, Norbert (University of Duisburg-Essen) ; Schmid, Matthias (University Hospital of Bonn. Institute of Medical Biometry) ; Schneider, Anja (German Center for Neurodegenerative Diseases (DZNE)) ; Selbæk, Geir (Oslo University Hospital.Department of Geriatric Medicine) ; Selnes, Per (Akershus University Hospital. Department of Neurology) ; Shadrin, Alexey (University of Oslo and Division of Mental Health. Institute of Clinical Medicine) ; Skoog, Ingmar (Sahlgrenska University Hospital (Suècia)) ; Soininen, Hilkka (University of Eastern Finland. Institute of Clinical Medicine.) ; Tárraga, Lluís (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Teipel, Stefan (Rostock University Medical Center. Department of Psychosomatic Medicine) ; Tijms, Betty M (Amsterdam Neuroscience. Neurodegeneration) ; Tsolaki, Magda (Aristotle University of Thessaloniki) ; Van Broeckhoven, Christine (Neurodegenerative Brain Diseases Group. VIB Center for Molecular Neurology. VIB) ; Van Dongen, Jasper (University of Antwerp. Department of Biomedical Sciences) ; van Swieten, John C. (Erasmus MC University Medical Center) ; Vandenberghe, Rik (Leuven Brain Institute. Department of Neurosciences.) ; Vidal, Jean‑Sébastien (Université Paris Cité) ; Visser, Pieter J. (Division of Neurogeriatrics Karolinska Institutet. Department of Neurobiology) ; Vogelgsang, Jonathan (Harvard Medical School. Department of Psychiatry) ; Waern, Margda (Sahlgrenska University Hospital (Suècia)) ; Wagner, Michael (German Center for Neurodegenerative Diseases (DZNE)) ; Wiltfang, Jens W (Medical Science Department. iBiMED) ; Wittens, Mandy M.J. (Vrije Universiteit Brussel) ; Zetterberg, Henrik (Hong Kong Center for Neurodegenerative Diseases) ; Zulaica, Miren (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; van Duijn, Cornelia M. (Nuffield Department of Population Health. Oxford University) ; Bjerke, Maria (Universitair Ziekenhuis Brussel) ; Engelborghs, Sebastiaan (Universitair Ziekenhuis Brussel. Department of Neurology) ; Jessen, Frank (University of Cologne) ; Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ; Pastor, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Hiltunen, Mikko (University of Eastern Finland. Institute of Biomedicine) ; Ingelsson, Martin (University of Toronto. Department of Medicine) ; Andreassen, Ole A (Oslo University Hospital (Oslo, Noruega)) ; Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Sleegers, Kristel (University of Antwerp. Department of Biomedical Sciences) ; Ruiz, Agustín (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Ramirez, Alfredo (Department of Psychiatry. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases) ; Cruchaga, Carlos (Washington University School of Medicine. Hope Center for Neurological Disorders) ; Lambert, Jean-Charles (Institut Pasteur de Lille) ; van der Flier, Wiesje M (Amsterdam Neuroscience. Neurodegeneration) ; Universitat Autònoma de Barcelona
Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer's disease (AD) more directly than clinical diagnosis. Initiated by the European Alzheimer & Dementia Biobank (EADB), the largest collaborative effort on genetics underlying CSF biomarkers was established, including 31 cohorts with a total of 13,116 individuals (discovery n = 8074; replication n = 5042 individuals). [...]
2022 - 10.1007/s00401-022-02454-z
Acta Neuropathologica, Vol. 144 Núm. 5 (november 2022) , p. 821-842  
6.
14 p, 3.0 MB Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset / Homann, Jan (Lübeck Interdisciplinary Platform for Genome Analytics. University of Lübeck) ; Osburg, Tim (Lübeck Interdisciplinary Platform for Genome Analytics. University of Lübeck) ; Ohlei, Olena (Lübeck Interdisciplinary Platform for Genome Analytics. University of Lübeck) ; Dobricic, Valerija (Lübeck Interdisciplinary Platform for Genome Analytics. University of Lübeck) ; Deecke, Laura (Lübeck Interdisciplinary Platform for Genome Analytics. University of Lübeck) ; Bos, Isabelle (Vrije Universiteit Amsterdam) ; Vandenberghe, Rik (Neurology Service. University Hospital Leuven) ; Gabel, Silvy (Laboratory for Cognitive Neurology. Department of Neurosciences. KU Leuven) ; Scheltens, Philip (Vrije Universiteit Amsterdam) ; Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ; Engelborghs, Sebastiaan (Vrije Universiteit Amsterdam) ; Frisoni, Giovanni B. (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Blin, Olivier (Institut Neurosciences Timone. AIX Marseille University) ; Richardson, Jill C. (Neurosciences Therapeutic Area. GlaxoSmithKline RD) ; Bordet, Régis (Lille Neuroscience and Cognition. University of Lille. Inserm. CHU Lille) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Popp, Julius (Old Age Psychiatry. Department of Psychiatry. University Hospital of Lausanne) ; Clark, Christopher (Department of Geriatric Psychiatry. University Hospital of Psychiatry Zurich) ; Peyratout, Gwendoline (Old Age Psychiatry. Department of Psychiatry. University Hospital of Lausanne) ; Martinez-Lage, Pablo (Department of Neurology. Center for Research and Advanced Therapies. CITA-Alzheimer Foundation) ; Tainta, Mikel (Department of Neurology. Center for Research and Advanced Therapies. CITA-Alzheimer Foundation) ; Dobson, Richard J.B. (NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust) ; Legido-Quigley, Cristina (King's College London. Institute of Pharmaceutical Sciences) ; Sleegers, Kristel (Center for Molecular Neurology) ; Van Broeckhoven, Christine (University of Antwerp) ; Wittig, Michael (Christian-Albrechts-University of Kiel. Institute of Clinical Molecular Biology) ; Franke, Andre (Christian-Albrechts-University of Kiel. Institute of Clinical Molecular Biology) ; Lill, Christina M. (Ageing Epidemiology Research Unit. School of Public Health. Imperial College London) ; Blennow, Kaj (Sahlgrenska University Hospital (Suècia)) ; Zetterberg, Henrik (University College London. UK Dementia Research Institute) ; Lovestone, Simon (University of Oxford. Department of Psychiatry) ; Streffer, Johannes ; ten Kate, Mara (Amsterdam UMC. University Medical Center) ; Vos, Stephanie J.B. (Maastricht University) ; Barkhof, Frederik (University College London) ; Visser, Pieter Jeller (Karolinska Institutet. Department of Neurobiology) ; Bertram, Lars (University of Oslo)
Alzheimer's disease (AD) is the most frequent neurodegenerative disease with an increasing prevalence in industrialized, aging populations. AD susceptibility has an established genetic basis which has been the focus of a large number of genome-wide association studies (GWAS) published over the last decade. [...]
2022 - 10.3389/fnagi.2022.840651
Frontiers in aging neuroscience, Vol. 14 (March 2022) , p. 840651  
7.
19 p, 1.3 MB State-of-the-art of lumbar puncture and its place in the journey of patients with Alzheimer's disease / Hampel, Harald (Eisai Inc. Neurology Business Group) ; Shaw, Leslie M. (Perelman School of Medicine. Department of Pathology and Laboratory Medicine. University of Pennsylvania) ; Aisen, Paul (USC Alzheimer's Therapeutic Research Institute) ; Chen, Christopher (Memory Aging and Cognition Centre. Departments of Pharmacology and Psychological Medicine. Yong Loo Lin School of Medicine. National University of Singapore) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Iwatsubo, Takeshi (Department of Neuropathology. Graduate School of Medicine. The University of Tokyo) ; Iwata, Atsushi (Tokyo Metropolitan Geriatric Hospital) ; Yamada, Masahito (Department of Neurology and Neurobiology of Aging. Kanazawa University Graduate School of Medical Science) ; Ikeuchi, Takeshi (Department of Molecular Genetics. Brain Research Institute. Niigata University) ; Jia, Jianping (Innovation Center for Neurological Disorders. Department of Neurology. Xuan Wu Hospital. Capital Medical University) ; Wang, Huali (Dementia Care and Research Center. Peking University Institute of Mental Health (Sixth Hospital). Beijing Dementia Key Lab. National Clinical Research Center for Mental Disorders) ; Teunissen, Charlotte E. (Amsterdam University Medical Centers (AUMC)) ; Peskind, Elaine (VA Northwest Mental Illness Research. Education and Clinical Center. VA Puget Sound Health Care System. Department of Psychiatry and Behavioral Sciences. University of Washington School of Medicine) ; Blennow, Kaj (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Cummings, Jeffrey (Chambers-Grundy Center for Transformative Neuroscience. Department of Brain Health. School of Integrated Health Sciences. University of Nevada Las Vegas (UNLV)) ; Vergallo, Andrea (Eisai Inc. Neurology Business Group) ; Universitat Autònoma de Barcelona
Recent advances in developing disease-modifying therapies (DMT) for Alzheimer's disease (AD), and the recognition that AD pathophysiology emerges decades before clinical symptoms, necessitate a paradigm shift of health-care systems toward biomarker-guided early detection, diagnosis, and therapeutic decision-making. [...]
2022 - 10.1002/alz.12372
Alzheimer's & Dementia, Vol. 18 Núm. 1 (january 2022) , p. 159-177  
8.
9 p, 1.5 MB The use of lumbar puncture and safety recommendations in Alzheimer's disease : a plain language summary / Hampel, Harald (Eisai Inc. Neurology Business Group) ; Elhage, Aya (Eisai Inc. Neurology Business Group) ; Shaw, Leslie M. (Perelman School of Medicine. Department of Pathology & Laboratory Medicine. University of Pennsylvania) ; Aisen, Paul (Usc Alzheimer's Therapeutic Research Institute) ; Chen, Christopher (Memory Aging & Cognition Centre. Departments of Pharmacology & Psychological Medicine. Yong Loo Lin School of Medicine. National University of Singapore) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Iwatsubo, Takeshi (Department of Neuropathology. Graduate School of Medicine. The University of Tokyo) ; Iwata, Atsushi (Tokyo Metropolitan Geriatric Hospital) ; Yamada, Masahito (Department of Neurology & Neurological Science. Tokyo Medical & Dental University) ; Ikeuchi, Takeshi (Department of Molecular Genetics. Brain Research Institute. Niigata University) ; Jia, Jianping (Innovation Center for Neurological Disorders. Department of Neurology. Xuan Wu Hospital. Capital Medical University) ; Wang, Huali (Dementia Care & Research Center. Peking University Institute of Mental Health (Sixth Hospital). Beijing Dementia Key Lab. National Clinical Research Center for Mental Disorders) ; Teunissen, Charlotte E. (Amsterdam University Medical Centers (AUMC)) ; Peskind, Elaine (Va Northwest Mental Illness Research. Education & Clinical Center. Va Puget Sound Health Care System. Department of Psychiatry & Behavioral Sciences. University of Washington School of Medicine) ; Blennow, Kaj (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Cummings, Jeffrey (Chambers-Grundy Center for Transformative Neuroscience. Department of Brain Health. School of Integrated Health Sciences. University of Nevada Las Vegas (UNLV)) ; Vergallo, Andrea (Eisai Inc. Neurology Business Group) ; Universitat Autònoma de Barcelona
What is this summary about? This is a plain language summary of an article published in Alzheimer's & Dementia. It looks at a type of test called a lumbar puncture (also known as spinal tap) used in people suspected of having Alzheimer's disease or some other form of dementia. [...]
2022 - 10.2217/nmt-2022-0012
Neurodegenerative Disease Management, Vol. 12 Núm. 5 (january 2022) , p. 221-229  
9.
12 p, 312.7 KB Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease : An international overview / Delaby, Constance (Institut d'Investigació Biomèdica Sant Pau) ; Teunissen, Charlotte E. (Vrije Universiteit Amsterdam) ; Blennow, Kaj (The Sahlgrenska Academy at the University of Gothenburg) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Arisi, Ivan (European Brain Research Institute (EBRI) "Rita Levi-Montalcini") ; Amar, Elodie Bouaziz (GHU APHP Nord Lariboisière Fernand-Widal Hospital) ; Beaume, Anne (CHU Poitiers) ; Bedel, Aurelie (CHU Bordeaux) ; Bellomo, Giovanni (University of Perugia) ; Bigot-Corbel, Edith (CHU de Nantes) ; Bjerke, Maria (University of Antwerp) ; Blanc-Quintin, Marie-Céline (APHP Centre-Université de Paris, Cochin Hospital) ; Boada, Mercè (Instituto de Salud Carlos III) ; Bousiges, Olivier (Hôpitaux Universitaires de Strasbourg) ; Chapman, Miles D (National Hospital for Neurology and Neurosurgery, UCL Queen Square) ; DeMarco, Mari L. (University of British Columbia) ; D'Onofrio, Mara (European Brain Research Institute (EBRI) "Rita Levi-Montalcini") ; Dumurgier, Julien (GHU APHP Nord Lariboisière Fernand-Widal Hospital) ; Dufour-Rainfray, Diane (CHU Tours) ; Engelborghs, Sebastiaan (Center for Neurosciences and Department of Neurology) ; Esselmann, Hermann (University Medical Center Goettingen (UMG) ; Fogli, Anne (CHU Clermont-Ferrand) ; Gabelle, Audrey (INSERM) ; Galloni, Elisabetta (Dipartimento di Neuroscienze Divisione di Neurologia) ; Gondolf, Clémentine (CHU Cote de Nacre Caen) ; Grandhomme, Frédérique (CHU Cote de Nacre Caen) ; Grau-Rivera, Oriol (Institut Hospital del Mar d'Investigacions Mèdiques) ; Hart, Melanie (National Hospital for Neurology and Neurosurgery, UCL Queen Square) ; Ikeuchi, Takeshi (Niigata University) ; Jeromin, Andreas (Cohen Veterans Bioscience) ; Kasuga, Kensaku (Niigata University) ; Keshavan, Ashvini (UCL Institute of Neurology (Regne Unit)) ; Khalil, Michael (Medical University of Graz) ; Körtvelyessy, Peter (German Center for Neurodegenerative Diseases, Magdeburg, Germany and Charité-Universitäts medizin Berlin) ; Kulczynska-Przybik, Agnieszka (Medical University of Bialystok) ; Laplanche, Jean-Louis (GHU APHP Nord Lariboisière Fernand-Widal Hospital) ; Lewczuk, Piotr (Universitätsklinikum Erlangen and Friedrich-Alexander Universität Erlangen-Nürnberg) ; Li, Qiao-Xin (Florey Institute and The University of Melbourne) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Malaplate, Catherine (Biologie Moléculaire et Nutrition/ Université de Lorraine) ; Marquié, Marta (Instituto de Salud Carlos III) ; Masters, Colin L. (Florey Institute and The University of Melbourne) ; Mroczko, Barbara (Medical University of Bialystok) ; Nogueira, Léonor (CHU PURPAN) ; Orellana, Adelina (Instituto de Salud Carlos III) ; Otto, Markus (University of Ulm) ; Oudart, Jean-Baptiste (Université de Reims Champagne-Ardenne) ; Paquet, Claire (GHU APHP Nord Lariboisière Fernand-Widal Hospital) ; Paoletti, Federico Paolini (University of Perugia) ; Parnetti, Lucilla (University of Perugia) ; Perret-Liaudet, Armand (Lyon University Hospital) ; Peoc'h, Katell (Université de Paris GHU APHP Nord Beaujon Hospital) ; Poesen, Koen (Leuven Brain Institute) ; Puig-Pijoan, Albert (Institut Hospital del Mar d'Investigacions Mèdiques) ; Quadrio, Isabelle (Lyon University Hospital) ; Quillard-Muraine, Muriel (Normandie Univ) ; Rucheton, Benoit (AP-HP Sorbonne University) ; Schraen, Susanna (Université de Lille) ; Schott, Jonathan M. (UCL Institute of Neurology (Regne Unit)) ; Shaw, Leslie M. (University of Pennsylvania) ; Suárez-Calvet, Marc (Institut Hospital del Mar d'Investigacions Mèdiques) ; Tsolaki, Magda (Aristotle University of Thessaloniki) ; Tumani, Hayrettin (University of Ulm) ; Udeh-Momoh, Chinedu T (Imperial College London) ; Vaudran, Lucie (Univ. Lille) ; Verbeek, Marcel M (Radboud University Medical Center) ; Verde, Federico ("Dino Ferrari" Center, Università degli Studi di Milano) ; Vermunt, Lisa (Vrije Universiteit Amsterdam) ; Vogelgsang, Jonathan (Harvard Medical School) ; Wiltfang, Jens (University of Aveiro) ; Zetterberg, Henrik (UCL Institute of Neurology (Regne Unit)) ; Lehmann, Sylvain (Université de Montpellier) ; Universitat Autònoma de Barcelona
The current practice of quantifying cerebrospinal fluid (CSF) biomarkers as an aid in the diagnosis of Alzheimer's disease (AD) varies from center to center. For a same biochemical profile, interpretation and reporting of results may differ, which can lead to misunderstandings and raises questions about the commutability of tests. [...]
2021 - 10.1002/alz.12545
Alzheimer's & Dementia, Vol. 18 (december 2021) , p. 1868-1879  
10.
15 p, 1.6 MB Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis / Fehmi, Janev (University of Oxford) ; Davies, Alexander J. (University of Oxford) ; Antonelou, Marilina (University College London) ; Keddie, Stephen (National Hospital of Neurology and Neurosurgery (Regne Unit)) ; Pikkupeura, Sonja (University of Oxford) ; Querol, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Delmont, Emilien (Hospital La Timone (França)) ; Cortese, Andrea (University of Pavia) ; Franciotta, Diego (Mondino Foundation) ; Persson, Staffan (Lund University) ; Barratt, Jonathan (University of Leicester) ; Pepper, Ruth (University College London) ; Farinha, Filipa (University College London) ; Rahman, Anisur (University College London) ; Canetti, Diana (University College London) ; Gilbertson, Janet A. (University College London) ; Rendell, Nigel B. (University College London) ; Radunovic, Aleksandar (Royal London Hospital) ; Minton, Thomas (University of Bristol) ; Fuller, Geraint (Gloucestershire Royal Hospital) ; Murphy, Sinead M. (Tallaght University Hospital & Academic Unit of Neurology (Irlanda)) ; Carr, Aisling S. (UCL Institute of Neurology (Regne Unit)) ; Reilly, Mary R. (UCL Institute of Neurology (Regne Unit)) ; Eftimov, Filip (Amsterdam UMC) ; Wieske, Luuk (Amsterdam UMC) ; Teunissen, Charlotte E. (Amsterdam UMC) ; Roberts, Ian S. D. (John Radcliffe Hospital (Regne Unit)) ; Ashman, Neil (The Royal London Hospital (Regne Unit)) ; Salama, Alan D. (University College London Department of Renal Medicine (Regne Unit)) ; Rinaldi, Simon (University of Oxford) ; Universitat Autònoma de Barcelona
Membranous glomerulonephritis (MGN) is a common cause of nephrotic syndrome in adults, mediated by glomerular antibody deposition to an increasing number of newly recognised antigens. Previous case reports have suggested an association between patients with anti-contactin-1 (CNTN1)-mediated neuropathies and MGN. [...]
2023 - 10.1371/journal.pone.0281156
PloS one, Vol. 18 (march 2023)  

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