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Articles, 2 registres trobats
Articles 2 registres trobats  
9 p, 310.0 KB Long-term safety and tolerability of apremilast in patients with psoriasis : Pooled safety analysis for ≥156 weeks from 2 phase 3, randomized, controlled trials (ESTEEM 1 and 2) / Crowley, Jeffrey (Bakersfield Dermatology) ; Thaçi, Diamant (Comprehensive Center for Inflammation Medicine, University Hospital Schleswig-Holstein) ; Joly, Pascal (Department of Dermatology, Hôpital Charles Nicolle, Université de Rouen) ; Peris, Ketty (Universitá Cattolica del Sacro Cuore, Roma) ; Papp,Kim A. (Probity Medical Research, Waterloo) ; Gonçalves, Joana (Celgene Corporation) ; Day, Robert M. (Celgene Corporation) ; Chen, Rongdean (Celgene Corporation) ; Shah, Kamal (Celgene Corporation) ; Ferrándiz, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cather, Jennifer C. (Modern Research Associates, Dallas) ; Universitat Autònoma de Barcelona
BACKGROUND: Randomized, controlled trials demonstrated efficacy and safety of apremilast for moderate-to-severe plaque psoriasis and psoriatic arthritis. OBJECTIVE: Assess long-term safety of oral apremilast in psoriasis patients. [...]
2017 - 10.1016/j.jaad.2017.01.052
Journal of the American Academy of Dermatology, Vol. 77 Núm. 2 (2017) , p. 310  
15 p, 1.4 MB Optimizing Anti-Inflammatory and Immunomodulatory Effects of Corticosteroid and Vitamin D Analogue Fixed-Dose Combination Therapy / Segaert, Siegfried (Leuven, Belgium) ; Shear, Neil H. (Toronto, Canada) ; Chiricozzi, Andrea (Pisa, Italy) ; Thaçi, Diamant (Lübeck, Germany) ; Carrascosa, Jose Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Young, Helen (Manchester, UK) ; Descamps, Vincent (Paris, France) ; Universitat Autònoma de Barcelona
Fixed-dose combination topical therapy with corticosteroid and vitamin D analog provides effective treatment and possible long-term management of psoriasis. The anti-inflammatory and immunomodulatory effects of corticosteroids and vitamin D analogs in treating psoriasis are well investigated; their complementary effects lead to the disruption of the inflammatory feedback loop underlying psoriasis pathogenesis. [...]
2017 - 10.1007/s13555-017-0196-z
Dermatology and Therapy, Vol. 7 (august 2017) , p. 265-279  

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