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5 p, 470.9 KB |
Spanish Cell Therapy Network (TerCel) : 15 years of successful collaborative translational research
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Sánchez-Guijo, Fermín (Universidad de Salamanca) ;
García-Olmo, Damián (Universidad Autónoma de Madrid) ;
Prósper, Felipe (Universidad de Navarra) ;
Martínez, Salvador (Instituto de Neurociencias UMH-CSIC) ;
Zapata, Agustín (Universidad Complutense de Madrid) ;
Fernandez Aviles, Francesc (IiSGM-Hospital General Universitario Gregorio Marañón) ;
Toledo-Aral, Juan José (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Torres, Miguel (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Fariñas, Isabel (Universitat de València) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Labandeira-García, José Luis (Universidade de Santiago de Compostela) ;
García-Sancho, Javier (Universidad de Valladolid) ;
Moraleda, José M. (Universidad de Murcia) ;
Universitat Autònoma de Barcelona
In the current article we summarize the 15-year experience of the Spanish Cell Therapy Network (TerCel), a successful collaborative public initiative funded by the Spanish government for the support of nationwide translational research in this important area. [...]
2020 -  10.1016/j.jcyt.2019.11.001
Cytotherapy, Vol. 22 Núm. 1 (january 2020) , p. 1-5
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18 p, 851.1 KB |
Clinical outcome measures in dementia with Lewy bodies trials : critique and recommendations
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Rodriguez-Porcel, Federico (Medical University of South Carolina) ;
Wyman-Chick, Kathryn A. (HealthPartners) ;
Abdelnour, Carla (Universitat Autònoma de Barcelona) ;
Toledo, Jon B. (University of Florida) ;
Ferreira, Daniel (Mayo Clinic) ;
Urwyler, Prabitha (University of Bern) ;
Weil, Rimona S. (University College London) ;
Kane, Joseph (Queen's University) ;
Pilotto, Andrea (University of Brescia) ;
Rongve, Arvid (The University of Bergen) ;
Boeve, Bradley (Mayo Clinic) ;
Taylor, John-Paul (Newcastle University) ;
McKeith, Ian (Newcastle University) ;
Aarsland, Dag (King's College London) ;
Lewis, Simon J. G. (University of Sydney)
The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of therapeutic benefit in clinical trials often relies on tools developed for other conditions, such as Alzheimer's or Parkinson's disease. [...]
2022 - 10.1186/s40035-022-00299-w
Translational Neurodegeneration, Vol. 11 (may 2022)
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1 p, 574.4 KB |
Correction : Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations
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Rodriguez-Porcel, Federico (Medical University of South Carolina) ;
Wyman-Chick, Kathryn A. (HealthPartners) ;
Abdelnour, Carla (Universitat Autònoma de Barcelona) ;
Toledo, Jon B. (University of Florida) ;
Ferreira, Daniel (Mayo Clinic) ;
Urwyler, Prabitha (University of Bern) ;
Weil, Rimona S. (University College London) ;
Kane, Joseph (Queen's University) ;
Pilotto, Andrea (University of Brescia) ;
Rongve, Arvid (The University of Bergen) ;
Boeve, Bradley (Mayo Clinic) ;
Taylor, John-Paul (Newcastle University) ;
McKeith, Ian (Newcastle University) ;
Aarsland, Dag (King's College London) ;
Lewis, Simon J. G. (University of Sydney)
The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of therapeutic benefit in clinical trials often relies on tools developed for other conditions, such as Alzheimer's or Parkinson's disease. [...]
2022 - 10.1186/s40035-022-00306-0
Translational Neurodegeneration, Vol. 11 (may 2022)
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18 p, 1.4 MB |
Dickkopf Proteins and Their Role in Cancer : A Family of Wnt Antagonists with a Dual Role
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Giralt, Irina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gallo-Oller, Gabriel (Vall d'Hebron Institut d'Oncologia) ;
Navarro Barea, Natalia (Vall d'Hebron Institut d'Oncologia) ;
Zarzosa, Patricia (Vall d'Hebron Institut d'Oncologia) ;
Pons, Guillem (Vall d'Hebron Institut d'Oncologia) ;
Magdaleno, Ainara (Vall d'Hebron Institut d'Oncologia) ;
Segura, Miguel F. (Vall d'Hebron Institut d'Oncologia) ;
Sánchez de Toledo, José (Vall d'Hebron Institut d'Oncologia) ;
Moreno, Lucas (Hospital Universitari Vall d'Hebron) ;
Gallego, Soledad (Hospital Universitari Vall d'Hebron) ;
Roma, Josep (Vall d'Hebron Institut d'Oncologia) ;
Universitat Autònoma de Barcelona
The Wnt signaling pathway regulates crucial aspects such as cell fate determination, cell polarity and organogenesis during embryonic development. Wnt pathway deregulation is a hallmark of several cancers such as lung, gastric and liver cancer, and has been reported to be altered in others. [...]
2021 - 10.3390/ph14080810
Pharmaceuticals, Vol. 14 (august 2021)
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14 p, 2.6 MB |
Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon
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Pons, Guillem (Hospital Universitari Vall d'Hebron) ;
Gallo-Oller, Gabriel (Hospital Universitari Vall d'Hebron) ;
Navarro Barea, Natalia (Hospital Universitari Vall d'Hebron) ;
Zarzosa, Patricia (Hospital Universitari Vall d'Hebron) ;
Sansa-Girona, Júlia (Hospital Universitari Vall d'Hebron) ;
García-Gilabert, Lia (Hospital Universitari Vall d'Hebron) ;
Magdaleno, Ainara (Hospital Universitari Vall d'Hebron) ;
Segura, Miguel F. (Hospital Universitari Vall d'Hebron) ;
Sánchez de Toledo Codin, Josep (Hospital Universitari Vall d'Hebron) ;
Gallego, Soledad (Hospital Universitari Vall d'Hebron) ;
Moreno, Lucas (Hospital Universitari Vall d'Hebron) ;
Roma, Josep (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
The identification of novel therapeutic targets for specific cancer molecular subtypes is crucial for the development of precision oncology. In the last few years, CRISPR/Cas9 screens have accelerated the discovery and validation of new targets associated with different tumor types, mutations, and fusions. [...]
2023 - 10.3390/cancers15061636
Cancers, Vol. 15 (march 2023)
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6.
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17 p, 1.1 MB |
Targeting the Hedgehog Pathway in Rhabdomyosarcoma
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Zarzosa, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Gilabert, Lia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hladun, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Guillén, Gabriela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gallo-Oller, Gabriel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pons, Guillem (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sansa-Girona, Julia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Segura, Miguel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez de Toledo Codin, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Moreno, Lucas (Vall d'Hebron Institut d'Oncologia) ;
Gallego, Soledad (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca)
In the first sections of this review, we provide a comprehensive description of the Hedgehog signalling pathway in mammals and the main general models of pathway activation. Subsequently, the review focuses on the oncogenic role played by this pathway in rhabdomyosarcoma and the inhibitors developed to date, as well as the clinical trials available in sarcomas. [...]
2023 - 10.3390/cancers15030727
Cancers, Vol. 15 (january 2023)
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11 p, 2.7 MB |
Unraveling Amazon tree community assembly using Maximum Information Entropy : a quantitative analysis of tropical forest ecology
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Pos, Edwin (Naturalis Biodiversity Center) ;
de Souza Coelho, Luiz (Instituto Nacional de Pesquisas da Amazônia) ;
de Andrade Lima Filho, Diogenes (Instituto Nacional de Pesquisas da Amazônia) ;
Salomão, Rafael P. (Museu Paraense Emílio Goeldi (Brasil)) ;
Amaral, Iêda Leão (Instituto Nacional de Pesquisas da Amazônia) ;
de Almeida Matos, Francisca Dionízia (Instituto Nacional de Pesquisas da Amazônia) ;
Castilho, Carolina V. (EMBRAPA - Centro de Pesquisa Agroflorestal de Roraima) ;
Phillips, Oliver L. (University of Leeds. School of Geography) ;
Guevara, Juan Ernesto (The Field Museum) ;
de Jesus Veiga Carim, Marcelo (Instituto de Pesquisas Científicas e Tecnológicas do Amapá. Departamento de Botânica) ;
López, Dairon Cárdenas (Herbario Amazónico Colombiano) ;
Magnusson, William E. (Instituto Nacional de Pesquisas da Amazônia) ;
Wittmann, Florian (Max Planck Institute for Chemistry) ;
Irume, Mariana Victória (Instituto Nacional de Pesquisas da Amazônia) ;
Martins, Maria Pires (Instituto Nacional de Pesquisas da Amazônia) ;
Sabatier, Daniel (Université de Montpellier) ;
da Silva Guimarães, José Renan (Instituto de Pesquisas Científicas e Tecnológicas do Amapá. Departamento de Botânica) ;
Molino, Jean-François (Université de Montpellier) ;
Bánki, Olaf (Naturalis Biodiversity Center) ;
Piedade, Maria Teresa Fernandez (Instituto Nacional de Pesquisas da Amazônia) ;
Pitman, Nigel C. A. (The Field Museum) ;
Mendoza, Abel Monteagudo (Jardín Botánico de Missouri) ;
Ramos, José Ferreira (Instituto Nacional de Pesquisas da Amazônia) ;
Hawes, Joseph E. (Anglia Ruskin University) ;
Almeida, Everton José (Universidade Federal de Mato Grosso) ;
Barbosa, Flávia Rodrigues (Universidade Federal de Mato Grosso) ;
Cavalheiro, Larissa (Universidade Federal de Mato Grosso) ;
dos Santos, Márcia Cléia Vilela (Universidade Federal de Mato Grosso) ;
Luize, Bruno Garcia (Universidade Estadual Paulista) ;
de Leão Novo, Evlyn Márcia Moraes (Instituto Nacional de Pesquisas Espaciais) ;
Vargas, Percy Núñez (Herbario Vargas, Universidad Nacional de San Antonio Abad del Cusco) ;
Silva, Thiago Sanna Freire (University of Stirling) ;
Venticinque, Eduardo Martins (Universidade Federal do Rio Grande do Norte.Departamento de Ecologia) ;
Manzatto, Angelo Gilberto (Universidade Federal de Rondônia. Departamento de Biologia) ;
Reis, Neidiane Farias Costa (Universidade Federal de Rondônia) ;
Terborgh, John (James Cook University. Centre for Tropical Environmental and Sustainability Science) ;
Casula, Katia Regina (Universidade Federal de Rondônia) ;
Coronado, Eurídice N. Honorio (Instituto de Investigaciones de la Amazonía Peruana) ;
Montero, Juan Carlos (Instituto Boliviano de Investigacion Forestal) ;
Marimon, Beatriz S. (Universidade do Estado de Mato Grosso) ;
Marimon Junior, Ben Hur (Universidade do Estado de Mato Grosso) ;
Feldpausch, Ted R. (University of Exeter) ;
Duque, Alvaro (Universidad Nacional de Colombia. Departamento de Ciencias Forestales) ;
Baraloto, Christopher (Florida International University. Department of Biological Sciences) ;
Arboleda, Nicolás Castaño (Herbario Amazónico Colombiano) ;
Engel, Julien (Florida International University) ;
Petronelli, Pascal (Univ Guyane) ;
Zartman, Charles Eugene (Instituto Nacional de Pesquisas da Amazônia) ;
Killeen, Timothy J. (Agteca-Amazonica) ;
Vasquez, Rodolfo (Jardín Botánico de Missouri) ;
Mostacedo, Bonifacio (Universidad Autónoma Gabriel René Moreno (Bolívia)) ;
Assis, Rafael L. (Natural History Museum, University of Oslo) ;
Schöngart, Jochen (Instituto Nacional de Pesquisas da Amazônia) ;
Castellanos, Hernán (Universidad Nacional Experimental de Guayana) ;
de Medeiros, Marcelo Brilhante (Embrapa Recursos Genéticos e Biotecnologia) ;
Simon, Marcelo Fragomeni (Embrapa Recursos Genéticos e Biotecnologia) ;
Andrade, Ana (Instituto Nacional de Pesquisas da Amazônia) ;
Camargo, José Luis (Instituto Nacional de Pesquisas da Amazônia) ;
Demarchi, Layon O. (Instituto Nacional de Pesquisas da Amazônia) ;
Laurance, William F. (James Cook University) ;
Laurance, Susan G. W. (James Cook University) ;
de Sousa Farias, Emanuelle (Instituto Oswaldo Cruz) ;
Lopes, Maria Aparecida (Universidade Federal do Pará) ;
Magalhães, José Leonardo Lima (Embrapa Amazônia Oriental) ;
Nascimento, Henrique Eduardo Mendonça (Instituto Nacional de Pesquisas da Amazônia) ;
de Queiroz, Helder Lima (Instituto de Desenvolvimento Sustentável Mamirauá) ;
Aymard, Gerardo A. C. (Herbario Universitario Portugal) ;
Brienen, Roel (University of Leeds) ;
Revilla, Juan David Cardenas (Instituto Nacional de Pesquisas da Amazônia) ;
Costa, Flávia R. C. (Instituto Nacional de Pesquisas da Amazônia) ;
Quaresma, Adriano (Instituto Nacional de Pesquisas da Amazônia) ;
Vieira, Ima Célia Guimarães (Museu Paraense Emílio Goeldi (Brasil)) ;
Cintra, Bruno Barçante Ladvocat (Universidade de Sao Paulo. Department of Botanica) ;
Stevenson, Pablo R. (Universidad de los Andes. Laboratorio de Ecología de Bosques Tropicales y Primatología) ;
Feitosa, Yuri Oliveira (Instituto Nacional de Pesquisas da Amazônia) ;
Duivenvoorden, Joost F. (University of Amsterdam. Institute of Biodiversity and Ecosystem Dynamics) ;
Mogollón, Hugo F. (Endangered Species Coalition) ;
Ferreira, Leandro Valle (Museu Paraense Emílio Goeldi (Brasil)) ;
Comiskey, James A. (Smithsonian Conservation Biology Institute. Center for Conservation and Sustainability) ;
Draper, Freddie (Carnegie Institution for Science (Washington, Estats Units d'Amèrica). Department of Global Ecology) ;
de Toledo, José Julio (Universidade Federal do Amapá) ;
Damasco, Gabriel (University of California. Department of Integrative Biology) ;
Dávila, Nállarett (Universidade Estadual de Campinas (Brasil)) ;
García-Villacorta, Roosevelt (Peruvian Center for Biodiversity and Conservation) ;
Lopes, Aline (University of Brasilia. Department of Ecology) ;
Vicentini, Alberto (Instituto Nacional de Pesquisas da Amazônia) ;
Noronha, Janaína Costa (ICNHS, Federal University of Mato Grosso) ;
Barbosa, Flávia Rodrigues (Federal University of Mato Grosso) ;
de Sá Carpanedo, Rainiellen (Federal University of Mato Grosso) ;
Emilio, Thaise (Royal Botanic Gardens) ;
Levis, Carolina (Wageningen University and Research) ;
de Jesus Rodrigues, Domingos (Federal University of Mato Grosso) ;
Schietti, Juliana (Instituto Nacional de Pesquisas da Amazônia) ;
Souza, Priscila (Instituto Nacional de Pesquisas da Amazônia) ;
Alonso, Alfonso (Smithsonian Conservation Biology Institute) ;
Dallmeier, Francisco (Smithsonian Conservation Biology Institute) ;
Gomes, Vitor H. F. (Universidade Federal do Pará) ;
Lloyd, Jonathan (Imperial College London. Department of Life Sciences) ;
Neill, David (Universidad Estatal Amazónica. Ecosistemas, Biodiversidad y Conservación de Especies) ;
de Aguiar, Daniel Praia Portela (Instituto Nacional de Pesquisas da Amazônia) ;
Araujo-Murakami, Alejandro (Universidad Autónoma Gabriel René Moreno (Bolívia)) ;
Arroyo, Luzmila (Universidad Autónoma Gabriel René Moreno (Bolívia)) ;
Carvalho, Fernanda Antunes (Universidade Federal de Minas Gerais) ;
de Souza, Fernanda Coelho (Instituto Nacional de Pesquisas da Amazônia) ;
do Amaral, Dário Dantas (Museu Paraense Emílio Goeldi (Brasil)) ;
Feeley, Kenneth J. (Fairchild Tropical Botanic Garden) ;
Gribel, Rogerio (Instituto Nacional de Pesquisas da Amazônia) ;
Pansonato, Marcelo Petratti (Universidade de Sao Paulo) ;
Barlow, Jos (Lancaster University) ;
Berenguer, Erika (University of Oxford. Environmental Change Institute) ;
Ferreira, Joice (Embrapa Amazônia Oriental) ;
Fine, Paul V. A. (University of California. Department of Integrative Biology) ;
Guedes, Marcelino Carneiro (Embrapa Amapá. Empresa Brasileira de Pesquisa Agropecuária) ;
Jimenez, Eliana M. (Universidad Nacional de Colombia Sede Amazonia) ;
Licona, Juan Carlos (Instituto Boliviano de Investigacion Forestal) ;
Mora, Maria Cristina Peñuela (Universidad Regional Amazónica IKIAM) ;
Peres, Carlos A. (University of East Anglia) ;
Zegarra, Boris Eduardo Villa (Direccíon de Evaluación Forestal y de Fauna Silvestre) ;
Cerón, Carlos (Universidad Central. Escuela de Biología Herbario Alfredo Paredes) ;
Henkel, Terry W. (Humboldt State University. Department of Biological Sciences) ;
Maas, Paul (Naturalis Biodiversity Center) ;
Silveira, Marcos (Universidade Federal do Acre) ;
Stropp, Juliana (Federal University of Alagoas. Institute of Biological and Health Sciences) ;
Thomas-Caesar, Raquel (Iwokrama International Centre for Rain Forest Conservation and Development) ;
Baker, Timothy R (University of Leeds. School of Geography) ;
Daly, Doug (New York Botanical Garden) ;
Dexter, Kyle G. (Royal Botanic Garden Edinburgh) ;
Householder, John Ethan (Karlsruhe Institute of Technology . Department of Wetland Ecology) ;
Huamantupa-Chuquimaco, Isau (Universidad Nacional de San Antonio Abad del Cusco) ;
Pennington, Toby (Royal Botanic Garden Edinburgh) ;
Paredes, Marcos Ríos (Servicios de Biodiversidad EIRL) ;
Fuentes, Alfredo (Center for Conservation and Sustainable Development) ;
Pena, José Luis Marcelo (Universidad Nacional de Jaén) ;
Silman, Miles R. (Wake Forest University. Biology Department and Center for Energy, Environment and Sustainability) ;
Tello, J. Sebastián (Missouri Botanical Garden) ;
Chave, Jerome (Université Paul Sabatier. Laboratoire Evolution et Diversité Biologique) ;
Valverde, Fernando Cornejo (Andes to Amazon Biodiversity Program) ;
Di Fiore, Anthony (University of Texas at Austin. Department of Anthropology) ;
Hilário, Renato Richard (Universidade Federal do Amapá) ;
Phillips, Juan Fernando (Fundación Puerto Rastrojo) ;
Rivas-Torres, Gonzalo (University of Florida. Department of Wildlife Ecology and Conservation) ;
van Andel, Tinde R. (Wageningen University. Biosystematics Group) ;
von Hildebrand, Patricio (Fundación Estación de Biología) ;
Barbosa, Edelcilio Marques (Instituto Nacional de Pesquisas da Amazônia) ;
de Matos Bonates, Luiz Carlos (Instituto Nacional de Pesquisas da Amazônia) ;
Doza, Hilda Paulette Dávila (Servicios de Biodiversidad EIRL) ;
Fonty, Émile (Direction Régionale de la Guyane) ;
Gómez, Ricardo Zárate (Instituto de Investigaciones de la Amazonía Peruana) ;
Gonzales, Therany (ACEER Foundation) ;
Gonzales, George Pepe Gallardo (Servicios de Biodiversidad EIRL) ;
Guillaumet, Jean-Louis (Muséum National d'histoire Naturelle de Paris) ;
Hoffman, Bruce (Amazon Conservation Team) ;
Junqueira, André B. (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
Malhi, Yadvinder (Oxford University Centre for the Environment) ;
de Andrade Miranda, Ires Paula (Instituto Nacional de Pesquisas da Amazônia) ;
Pinto, Linder Felipe Mozombite (Servicios de Biodiversidad) ;
Prieto, Adriana (Universidad Nacional de Colombia) ;
Rudas, Agustín (Universidad Nacional de Colombia) ;
Ruschel, Ademir R. (Embrapa Amazônia Oriental) ;
Silva, Natalino (Universidade Federal Rural da Amazônia) ;
Vela, César I. A. (Universidad Nacional de San Antonio Abad del Cusco) ;
Vos, Vincent Antoine (Universidad Autónoma del Beni José Ballivián) ;
Zent, Egleé L. (Instituto Venezolano de Investigaciones Científicas) ;
Zent, Stanford (Instituto Venezolano de Investigaciones Científicas) ;
Albuquerque, Bianca Weiss (Instituto Nacional de Pesquisas da Amazônia) ;
Cano, Angela (Cambridge University Botanic Garden) ;
Correa Gómez, Diego Felipe (The University of Queensland) ;
Costa, Janaina Barbosa Pedrosa (Embrapa Amapá. Empresa Brasileira de Pesquisa Agropecuária) ;
Flores, Bernardo Monteiro (University of Campinas. Plant Biology Department) ;
Holmgren, Milena (Wageningen University and Research) ;
Nascimento, Marcelo Trindade (Universidade Estadual do Norte Fluminense. Laboratório de Ciências Ambientais) ;
Oliveira, Alexandre A. (Universidade de Sao Paulo) ;
Ramirez-Angulo, Hirma (Universidad de los Andes. Instituto de Investigaciones Para el Desarrollo Forestal) ;
Rocha, Maira (Instituto Nacional de Pesquisas da Amazônia) ;
Scudeller, Veridiana Vizoni (Universidade Federal do Amazonas) ;
Sierra, Rodrigo (GeoIS) ;
Tirado, Milton (GeoIS) ;
Umaña, Maria Natalia (University of Michigan. Department of Ecology and Evolutionary Biology) ;
van der Heijden, Geertje (University of Nottingham) ;
Torre, Emilio Vilanova (University of Washington. School of Environmental and Forest Sciences) ;
Vriesendorp, Corine (The Field Museum) ;
Wang, Ophelia (Northern Arizona University) ;
Young, Kenneth R. (University of Texas at Austin) ;
Reategui, Manuel Augusto Ahuite (Medio Ambiente) ;
Baider, Cláudia (Ministry of Agro-Industry and Food Security) ;
Balslev, Henrik (Aarhus University. Department of Bioscience) ;
Cárdenas, Sasha (Universidad de los Andes) ;
Casas, Luisa Fernanda (Universidad de los Andes) ;
Farfan-Rios, William (Washington University in Saint Louis) ;
Ferreira, Cid (Instituto Nacional de Pesquisas da Amazônia) ;
Linares-Palomino, Reynaldo (Smithsonian Conservation Biology Institute. Center for Conservation and Sustainability) ;
Mendoza, Casimiro (Manejo Forestal en Las Tierras Tropicales de Bolivia) ;
Mesones, Italo (University of California. Department of Integrative Biology) ;
Torres-Lezama, Armando (Universidad de los Andes) ;
Giraldo, Ligia Estela Urrego (Universidad Nacional de Colombia. Departamento de Ciencias Forestales) ;
Villarroel, Daniel (Universidad Autónoma Gabriel René Moreno (Bolívia)) ;
Zagt, Roderick (Tropenbos International) ;
Alexiades, Miguel N. (University of Kent. School of Anthropology and Conservation) ;
Garcia-Cabrera, Karina (Wake Forest University. Biology Department) ;
Hernandez, Lionel (Universidad Nacional Experimental de Guayana) ;
Milliken, William (Royal Botanic Gardens) ;
Cuenca, Walter Palacios (Universidad Técnica del Norte) ;
Pansini, Susamar (Universidade Federal de Rondônia) ;
Pauletto, Daniela (Universidade Federal do Oeste do Pará. Instituto de Biodiversidade e Floresta) ;
Arevalo, Freddy Ramirez (Universidad Nacional de la Amazonia Peruana) ;
Sampaio, Adeilza Felipe (Universidade Federal de Rondônia) ;
Sandoval, Elvis H. Valderrama (University of Missouri. Department of Biology) ;
Gamarra, Luis Valenzuela (Jardín Botánico de Missouri) ;
Boenisch, Gerhard (Max-Planck-Institute for Biogeochemistry. Department of Biogeochemical Integration) ;
Kattge, Jens (Max-Planck-Institute for Biogeochemistry. Functional Biogeography) ;
Kraft, Nathan (UCLA. Department of Ecology and Evolutionary Biology) ;
Levesley, Aurora (University of Leeds. School of Geography) ;
Melgaço, Karina (University of Leeds. School of Geography) ;
Pickavance, Georgia (University of Leeds. School of Geography) ;
Poorter, Lourens (Wageningen University and Research) ;
ter Steege, Hans (Naturalis Biodiversity Center)
In a time of rapid global change, the question of what determines patterns in species abundance distribution remains a priority for understanding the complex dynamics of ecosystems. The constrained maximization of information entropy provides a framework for the understanding of such complex systems dynamics by a quantitative analysis of important constraints via predictions using least biased probability distributions. [...]
2023 - 10.1038/s41598-023-28132-y
Scientific reports, Vol. 13 (February 2023) , art. 2859
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7 p, 823.4 KB |
Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease
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Jost, Stefanie Theresa (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Visser-Vandewalle, Veerle (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Stereotaxy and Functional Neurosurgery) ;
Rizos, Alexandra Marianne (King's College London. Parkinson Foundation International Centre of Excellence) ;
Loehrer, Philipp Alexander (Department of Neurology. University Hospital Giessen and Marburg. Campus Marburg) ;
Silverdale, Monty (Department of Neurology and Neurosurgery. Salford Royal NHS Foundation Trust. Manchester Academic Health Science Centre. University of Manchester) ;
Evans, Julian (Department of Neurology and Neurosurgery. Salford Royal NHS Foundation Trust. Manchester Academic Health Science Centre. University of Manchester) ;
Samuel, Michael (King's College London. Parkinson Foundation International Centre of Excellence) ;
Petry-Schmelzer, Jan Niklas (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Sauerbier, Anna (Institute of Psychiatry. Psychology and Neuroscience. King's College London) ;
Gronostay, Alexandra (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Barbe, Michael T. (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Fink, Gereon R. (Cognitive Neuroscience. Institute of Neuroscience and Medicine (INM-3). Research Centre Jülich) ;
Ashkan, Keyoumars (King's College London. Parkinson Foundation International Centre of Excellence) ;
Antonini, Angelo (Padova University. Department of Neurosciences (DNS)) ;
Martinez-Martin, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Chaudhuri, Kallol Ray (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Timmermann, Lars (University Hospital Giessen and Marburg) ;
Dafsari, Haidar S. (University of Cologne. Faculty of Medicine and University Hospital Cologne. Department of Neurology) ;
Bhidayasiri, Roongroj (Chulalongkorn Centre of Excellence for Parkinson's Disease & Related Disorders. Department of Medicine. Faculty of Medicine. Chulalongkorn University and King Chulalongkorn Memorial Hospital. Thai Red Cross Society) ;
Falup-Pecurariu, Cristian (Faculty of Medicine. Transilvania University of Brașov) ;
Jeon, Beomseok (Department of Neurology. Seoul National University College of Medicine) ;
Leta, Valentina (King's College London. Institute of Psychiatry. Psychology & Neuroscience) ;
Borghammer, Per (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Odin, Per (University of Lund. Faculty of Medicine) ;
Schrag, Anette (UCL Institute of Neurology (Regne Unit)) ;
Storch, Alexander (German Center for Neurodegenerative Diseases (DZNE). Research Site Dresden) ;
Rodríguez-Violante, Mayela (Movement Disorders Clinic. National Institute of Neurology and Neurosurgery) ;
Weintraub, Daniel (Parkinson's Disease and Mental Illness Research. Education and Clinical Centers. Philadelphia Veterans Affairs Medical Center) ;
Adler, Charles (The Parkinson's Disease and Movement Disorders Center. Department of Neurology. Mayo Clinic) ;
Barone, Paolo (Center for Neurodegenerative Diseases (CEMAND). Neuroscience Section. University of Salerno) ;
Brooks, David J. (Department of Nuclear Medicine and PET Centre. Aarhus University Hospital) ;
Brown, Richard (Department of Medicine. University of Birmingham Institute of Cardiovascular Sciences. City Hospital) ;
Cantillon, Marc (Reviva Pharmaceuticals. Inc) ;
Carroll, Camille (Faculty of Medicine and Dentistry. University of Plymouth) ;
Coelho, Miguel (FAS Center for Systems Biology. Harvard University) ;
Henriksen, Tove (Movement Disorder Clinic. University Hospital of Bispebjerg) ;
Hu, Michele (Nuffield Department of Clinical Neurosciences. University of Oxford) ;
Jenner, Peter (Neurodegenerative Diseases Research Group. Institute of Pharmaceutical Sciences. Faculty of Life Sciences and Medicine. King's College London) ;
Kramberger, Milica (Department of Neurology. University Medical Centre Ljubljana) ;
Kumar, Padma (Parkinson's Disease Service for the Older Person. Rankin Park Centre. John Hunter Hospital. HNELHD) ;
Kurtis, Monica M. (Functional Movement Disorders Unit. Movement Disorders Program. Neurology Department. Hospital Ruber Internacional) ;
Lewis, Simon (Brain and Mind Centre. University of Sydney) ;
Litvan, Irene (Department of Neurosciences Movement Disorders Center. University of California) ;
Lyons, Kelly (University of Kansas Medical Center) ;
Martino, Davide (Department of Clinical Neurosciences. University of Calgary & Hotchkiss Brain Institute) ;
Masellis, Mario (Hurvitz Brain Sciences Program. Sunnybrook Research Institute) ;
Mochizuki, Hideki (Department of Neurology. Osaka University Graduate School of Medicine) ;
Morley, James F. (Department of Neurology. University of Pennsylvania) ;
Nirenberg, Melissa (Department of Neurology. NYU School of Medicine) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Panicker, Jalesh (Neurology. National Hospital for Neurology & Neurosurgery) ;
Pavese, Nicola (Newcastle Magnetic Resonance Centre & Positron Emission Tomography Centre. Newcastle University. Campus for Ageing & Vitality) ;
Pekkonen, Eero (Department of Neurology. Helsinki University Hospital. and Department of Neurological Sciences (Neurology). University of Helsinki) ;
Postuma, Ron (Research Institute of McGill University Health Centre) ;
Rosales, Raimon L. (Center for Neurodiagnostic and Therapeutic Services. Metropolitan Medical Center) ;
Schapira, Anthony (Department of Clinical Neurosciences. University College London (UCL) Institute of Neurology. Royal Free Campus. Rowland Hill Street) ;
Simuni, Tanya (Department of Neurology. Northwestern University. Feinberg School of Medicine) ;
Stocchi, Fabrizio (University and Institute for Research and Medical Care. IRCCS San Raffaele) ;
Subramanian, Indu (UCLA/West LA VA) ;
Tagliati, Michele (Cedars-Sinai Medical Center) ;
Tinazzi, Michele (Department of Neuroscience. Biomedicine. and Movement. University of Verona) ;
Toledo, Jon (Department of Neurology. Houston Methodist Hospital) ;
Tsuboi, Yoshio (Department of Neurology. Fukuoka University) ;
Walker, Richard (Northumbria Healthcare NHS Foundation Trust. North Tyneside General Hospital. Rake Lane)
To identify predictors of 36-month follow-up quality of life (QoL) outcome after bilateral subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD). In this ongoing, prospective, multicenter international study (Cologne, Manchester, London) including 73 patients undergoing STN-DBS, we assessed the following scales preoperatively and at 6-month and 36-month follow-up: PD Questionnaire-8 (PDQ-8), NMSScale (NMSS), Scales for Outcomes in PD (SCOPA)-motor examination, -activities of daily living, and -complications, and levodopa equivalent daily dose (LEDD). [...]
2021 - 10.1038/s41531-021-00174-x
NPJ Parkinson's disease, Vol. 7 Núm. 1 (december 2021) , p. 48
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10 p, 1.7 MB |
The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis
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París-Coderch, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jiménez Jiménez, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Erazo, Tatiana (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Muñoz-Guardiola, Pau (Ability Pharmaceuticals) ;
Masanas, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Antonelli, Roberta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Boloix, Ariadna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alfón, José (Ability Pharmaceuticals) ;
Pérez-Montoyo, Héctor (Ability Pharmaceuticals) ;
Yeste-Velasco, Marc (Ability Pharmaceuticals) ;
Domènech, Carles (Ability Pharmaceuticals) ;
Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez de Toledo Codin, Josep (Vall d'Hebron Institut d'Oncologia) ;
Moreno, Lucas (Vall d'Hebron Institut d'Oncologia) ;
Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Gallego, Soledad (Vall d'Hebron Institut d'Oncologia) ;
Segura, Miguel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Neuroblastoma is the leading cause of cancer death in children aged 1 to 4 years. Particularly, five-year overall survival for high-risk neuroblastoma is below 50% with no curative options when refractory or relapsed. [...]
2020 - 10.1038/s41419-020-02986-w
Cell death and disease, Vol. 11 (september 2020)
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17 p, 3.9 MB |
CN133, a Novel Brain-Penetrating Histone Deacetylase Inhibitor, Hampers Tumor Growth in Patient-Derived Pediatric Posterior Fossa Ependymoma Models
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Antonelli, Roberta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jiménez Jiménez, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Riley, Misha (Massachusetts General Hospital (Boston)) ;
Servidei, Tiziana (Fondazione Policlinico Universitario "A. Gemelli" (Roma, Itàlia)) ;
Riccardi, Riccardo (Fondazione Policlinico Universitario "A. Gemelli" (Roma, Itàlia)) ;
Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martini, Maurizio (Catholic University of Sacred Heart) ;
Ruggiero, Antonio (Fondazione Policlinico Universitario "A. Gemelli" (Roma, Itàlia)) ;
Moreno, Lucas (Vall d'Hebron Institut d'Oncologia) ;
Sánchez de Toledo Codin, Josep (Vall d'Hebron Institut d'Oncologia) ;
Gallego, Soledad (Vall d'Hebron Institut d'Oncologia) ;
Bové, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hooker, Jacob M. (Massachusetts General Hospital (Boston)) ;
Segura, Miguel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Pediatric ependymoma (EPN) is a highly aggressive tumor of the central nervous system that remains incurable in 40% of cases. In children, the majority of cases develop in the posterior fossa and can be classified into two distinct molecular entities: EPN posterior fossa A (PF-EPN-A) and EPN posterior fossa B (PF-EPN-B). [...]
2020 - 10.3390/cancers12071922
Cancers, Vol. 12 (july 2020)
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