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8 p, 4.7 MB Nitric oxide-dependent biodegradation of graphene oxide reduces inflammation in the gastrointestinal tract / Peng, Guotao (Karolinska Institutet (Estocolm, Suècia). Institute of Environmental Medicine) ; Montenegro, Marcelo F. (Karolinska Institutet (Estocolm, Suècia). Department of Physiology and Pharmacology) ; Ntola, Chifundo N. M. (University of Manchester. National Graphene Institute) ; Vranic, Sandra (University of Manchester. National Graphene Institute) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ; Vogt, Carmen (Kungl. Tekniska högskolan (Estocolm (Suècia)) ; Toprak, Muhammet S. (Kungl. Tekniska högskolan (Estocolm (Suècia)) ; Duan, Tianbo (Uppsala University. Department of Engineering Sciences) ; Leifer, Klaus (Uppsala University. Department of Engineering Sciences) ; Bräutigam, Lars (Karolinska Institutet (Estocolm, Suècia)) ; Lundberg, Jon O. (Karolinska Institutet (Estocolm, Suècia). Department of Physiology and Pharmacology) ; Fadeel, Bengt (Karolinska Institutet (Estocolm, Suècia). Institute of Environmental Medicine)
Understanding the biological fate of graphene-based materials such as graphene oxide (GO) is crucial to assess adverse effects following intentional or inadvertent exposure. Here we provide first evidence of biodegradation of GO in the gastrointestinal tract using zebrafish as a model. [...]
2020 - 10.1039/d0nr03675g
Nanoscale, Vol. 12, Issue 32 (August 2020) , p. 16730-16737  

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