|
1.
|
|
10 p, 825.0 KB |
Neuropeptide-S-receptor deficiency affects sex-specific modulation of safety learning by pre-exposure to electric stimuli
/
Kreutzmann, Judith.C. (Department of Systems Physiology of Learning. Leibniz Institute for Neurobiology) ;
Khalil, Radwa (Otto-von-Guericke University Magdeburg. Institute for Pharmacology & Toxicology) ;
Köhler, Jana C. (Otto-von-Guericke University Magdeburg. Center of Behavioral Brain Sciences) ;
Mayer, Dana (Otto-von-Guericke University Magdeburg. Institute for Pharmacology & Toxicology) ;
Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fendt, Markus (Otto-von-Guericke University Magdeburg. Center of Behavioral Brain Sciences)
Neuropeptide S (NPS) is a neuropeptide involved in the regulation of fear. Because safety learning is impaired in patients suffering from anxiety-related psychiatric disorders, and polymorphisms of the human neuropeptide S receptor (NPSR) gene have also been associated with anxiety disorders, we wanted to investigate whether NPSR-deficiency interferes with safety learning, and how prior stress would affect this type of learning. [...]
2020 -  10.1111/gbb.12621
Genes, Brain and Behavior, Vol. 19 Núm. 3 (January 2020) , p. e12621
|
|
|
2.
|
|
14 p, 1.9 MB |
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients : a randomised controlled trial
/
Chastre, Jean (Service de Médecine Intensive Réanimation. Institut de Cardiologie. Groupe Hospitalier Pitié-Salpêtrière. Assistance Publique-Hôpitaux de Paris. Sorbonne University) ;
François, Bruno (Réanimation Polyvalente and Inserm CIC 1435 & UMR 1092. CHU) ;
Bourgeois, Marc (AZ Sint-Jan Brugge-Oostende AV) ;
Komnos, Apostolos (General Hospital of Larissa) ;
Ferrer, Ricard (Hospital Universitari Vall d'Hebron) ;
Rahav, Galia (Chaim Sheba Medical Center. Sackler School of Medicine. Tel Aviv University) ;
De Schryver, Nicolas (Clinique Saint-Pierre) ;
Lepape, Alain (Hospices Civils de Lyon Hôpital Lyon Sud) ;
Koksal, Iftihar (Faculty of Medicine. Trabzon and Acibadem University Faculty of Medicine. Karadeniz Technical University) ;
Luyt, Charles-Edouard (Service de Médecine Intensive Réanimation. Institut de Cardiologie. Groupe Hospitalier Pitié-Salpêtrière. Assistance Publique-Hôpitaux de Paris. Sorbonne University) ;
Sánchez-García, Miguel (Hospital Clínico San Carlos. Unidad de Cuidados Intensivos) ;
Torres, Antoni (Hospital Clínic i Provincial de Barcelona. Servei de Pneumologia) ;
Eggimann, Philippe (Department of Locomotor Apparatus. Centre Hospitalier Universitaire Vaudois CHUV) ;
Koulenti, Despoina (2nd Critical Care Department. Attikon University Hospital. National and Kapodistrian. University of Athens) ;
Holland, Thomas L. (Duke Clinical Research Institute) ;
Ali, Omar (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Shoemaker, Kathryn (Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Ren, Pin (Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Sauser, Julien (Infection Control Program. Faculty of Medicine. Geneva University Hospitals) ;
Ruzin, Alexey (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Tabor, David E. (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Akhgar, Ahmad (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
Wu, Yuling (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
Jiang, Yu (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
DiGiandomenico, Antonio (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Colbert, Susan (Oncology. US SM&M. AstraZeneca) ;
Vandamme, Drieke (Inserm CIC 1435. CHU) ;
Coenjaerts, Frank (University Medical Center Utrecht) ;
Malhotra-Kumar, Surbhi (University of Antwerp. Laboratory of Medical Microbiology) ;
Timbermont, Leen (University of Antwerp. Laboratory of Medical Microbiology) ;
Oliver, Antonio (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Barraud, Olivier (INSERM U1092. Centre Hospitalier Universitaire de Limoges. Université Limoges) ;
Bellamy, Terramika (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Bonten, Marc (Julius Center for Health Science and Primary Care. University Medical Center Utrecht. Utrecht University) ;
Goossens, Herman (Laboratory of Medical Microbiology. Vaccine and Infectious Disease Institute. University of Antwerp) ;
Reisner, Colin (DevPro Biopharma) ;
Esser, Mark T. (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Jafri, Hasan S. (Late-Stage Development. Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Joannidis, Michael ;
Klimscha, Walter ;
De Waele, Elisabeth ;
Devriendt, Jacques ;
Huberlant, Vincent ;
Depuydt, Pieter ;
Van Boxstael, Sam ;
Peric, Mladen ;
Kopic, Jasminka ;
Hanauer, Michal ;
Hruby, Tomas ;
Sramek, Vladimir ;
Svoboda, Petr ;
Vymazal, Tomas ;
Novacek, Martin ;
Annane, Djillali ;
Mira, Jean-Paul ;
Souweine, Bertrand ;
Dequin, Pierre-François ;
Meziani, Ferhat ;
Stephan, François ;
Nseir, Saad ;
Gibot, Sebastien ;
Schwebel, Carole ;
Plantefeve, Gaetan ;
Diehl, Jean-Luc ;
Richard, Christian ;
Lamer, Christian ;
Klouche, Kada ;
Jaber, Samir ;
Zakynthinos, Epaminondas ;
Filntisis, Georgios ;
Zakynthinos, Spyros ;
Koutsoukou, Antonia ;
Saroglou, Georgios ;
Nikolaou, Charikleia ;
Vlachogianni, Glykeria ;
Pnevmatikos, Ioannis ;
Mandragos, Konstantinos ;
Kremer, Ildiko ;
Rozgonyi, Zsolt Dezso ;
Marjanek, Zsuzsa ;
Martin-Loeches, Ignacio ;
Singer, Pierre ;
Van Heerden, Vernon ;
Carmeli, Yehuda ;
Povoa, Pedro ;
AlvarezSeoane, Antonio ;
Moura, Pedro ;
Gonzalez, Filipe ;
Ramirez, Paula ;
Torres Marti, Antonio ;
Ferrer Roca, Ricard ;
Oteiza, Lorena ;
Escudero, Dolores ;
Piacentini, Enrique ;
Vera-Artazcoz, Paula (Institut d'Investigació Biomèdica Sant Pau) ;
Tamayo, Luis ;
Gonzalez Gallego, Miguel Angel ;
Suberviola Canas, Borja ;
Figueira, Iglesias ;
Leon, Rafael ;
Korten, Volkan ;
Akova, Murat ;
Wyncoll, Duncan ;
Whitehouse, Tony ;
Hopkins, Phil ;
Sim, Malcolm ;
Golan, Yoav ;
Zervos, Marcus ;
Vazquez, Jose ;
Cherabuddi, Kartikeya ;
Smulian, George ;
Rouphael, Nadine ;
Welker, James ;
Sims, Mathew ;
Van Duin, David ;
McCarthy, Todd ;
Polk, Christopher
Background: Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) in preventing PA nosocomial pneumonia was assessed in PA-colonised mechanically ventilated subjects. [...]
2022 - 10.1186/s13054-022-04204-9
Critical Care, Vol. 26 Núm. 1 (december 2022) , p. 355
|
|
|
3.
|
|
13 p, 668.0 KB |
Glucocorticoid-based pharmacotherapies preventing PTSD
/
Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Velasco, Eric Raúl (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Monari, Sílvia (Geneva University Hospitals. Department of Psychiatry) ;
Cano, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Cardoner, N. (Narcís) (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Sandi, Carmen (École Polytechnique Fédérale de Lausanne (Suïssa). Brain Mind Institute) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Perez-Caballero, Laura (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Posttraumatic stress disorder (PTSD) is a highly disabling psychiatric condition that may arise after exposure to acute and severe trauma. It is a highly prevalent mental disorder worldwide, and the current treatment options for these patients remain limited due to low effectiveness. [...]
2023 - 10.1016/j.neuropharm.2022.109344
Neuropharmacology, Vol. 224 (2023) , 109344
|
|
|
4.
|
|
|
5.
|
|
17 p, 3.3 MB |
PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus
/
Velasco García, Eric Raúl (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Flores, África (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Senabre, Eric (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Gomez-Gomez, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Torres, A. (Hospital Clínic i Provincial de Barcelona) ;
Roca, A. (Hospital Clínic i Provincial de Barcelona) ;
Norrholm, S. (Wayne State University. Department of Psychiatry and Behavioral Neuroscience) ;
Newman, Emily L. (McLean Hospital. Department of Psychiatry. Harvard Medical School) ;
Das, P. (Department of Neuroscience. Albert Einstein College of Medicine) ;
Ross, R.A. (Department of Neuroscience. Albert Einstein College of Medicine) ;
Lori, Adriana (Emory University) ;
Pozo, Oscar J (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ressler, Kerry J. (McLean Hospital. Department of Psychiatry. Harvard Medical School) ;
Garcia-Esteve, L.L. (Hospital Clínic i Provincial de Barcelona) ;
Jovanovic, T. (Wayne State University. Department of Psychiatry and Behavioral Neuroscience) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut)
Exposure to traumatic stress can lead to fear dysregulation, which has been associated with posttraumatic stress disorder (PTSD). Previous work showed that a polymorphism in the PACAP-PAC1R (pituitary adenylate cyclase-activating polypeptide) system is associated with PTSD risk in women, and PACAP (ADCYAP1)-PAC1R (ADCYAP1R1) are highly expressed in the hypothalamus. [...]
2022 - 10.1038/s41467-022-31442-w
Nature communications, Vol. 13 Núm. 1 (december 2022) , p. 4374
|
|
|
6.
|
|
19 p, 3.5 MB |
Sex differences in fear memory consolidation via Tac2 signaling in mice
/
Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Velasco García, Eric Raúl (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Soto-Faguás, C. M. (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Gomez-Gomez, A. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Perez-Caballero, Laura (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Molina, P. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Pozo, Oscar J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Saura Antolín, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Andero Galí, Raül (Universitat Autònoma de Barcelona. Institut de Neurociències)
Memory formation is key for brain functioning. Uncovering the memory mechanisms is helping us to better understand neural processes in health and disease. Moreover, more specific treatments for fear-related disorders such as posttraumatic stress disorder and phobias may help to decrease their negative impact on mental health. [...]
2021 - 10.1038/s41467-021-22911-9
Nature communications, Vol. 12 (may 2021)
|
|
|
7.
|
|
9 p, 963.7 KB |
Proposal of a clinical care pathway for quality and safe management of headache patients : a consensus study report
/
Pascual Gómez, Julio (Universidad de Cantabria) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Carrillo, Irene (Universidad Miguel Hernández de Elche) ;
Rodríguez-Justo, Sandra (Complexo Hospitalario Universitario de Vigo) ;
Jiménez-Hernández, Dolores (Universidad de Sevilla) ;
Layos-Romero, Almudena (Complejo Hospitalario Universitario de Albacete) ;
Bailón-Santamaría, Cristina (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Torres, Antonio (Andalusian Agency for Healthcare Quality) ;
Martínez-García, Alba (Universidad Miguel Hernández de Elche) ;
Ignacio, Emilio (Universidad de Cádiz) ;
Mira, José Joaquín (Alicante-Sant Joan Health District)
Headache is one of the most prevalent and disabling conditions. Its optimal management requires a coordinated and comprehensive response by health systems, but there is still a wide variability that compromises the quality and safety of the care process. [...]
2020 - 10.1136/bmjopen-2020-037190
BMJ open, Vol. 10 (october 2020)
|
|
|
8.
|
|
8 p, 365.5 KB |
Low-value care practice in headache : a Spanish mixed methods research study
/
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Layos-Romero, Almudena (Complejo Hospitalario Universitario de Albacete) ;
Martin-Delgado, Jimmy (ATENEA research group (Alacant)) ;
Pascual Gómez, Julio (Universidad de Cantabria) ;
Bailón-Santamaría, Cristina (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Tentor, Ana (Barrio del Pilar Health Center (Madrid)) ;
Santiago, Alejandro (Hospital Universitario Infanta Leonor) ;
Ignacio, Emilio (Cádiz University) ;
Torrés, Antonio (Patient Safety Observatory, Andalusian Healthcare Quality Agency, Seville, Spain) ;
Mira, José Joaquín (Universitat Miguel Hernández) ;
Universitat Autònoma de Barcelona
Headache is one of the most prevalent diseases. The Global Burden of Disease Study ranks it as the seventh most common disease overall and the second largest neurological cause of disability in the world. [...]
2020 - 10.1186/s10194-020-01147-w
Journal of headache and pain, Vol. 21 (june 2020)
|
|
|
9.
|
|
17 p, 443.2 KB |
Play as a stimulator for the development of children with West syndrome and other epileptic encephalopathies at early ages
/
Del Toro Alonso, Víctor (Universidad Complutense de Madrid) ;
Gútiez Cuevas, Pilar (Universidad Complutense de Madrid) ;
Torres González, José Antonio (Universidad de Jaén)
Games can be an ideal tool to stimulate the development of children aged 0 to 6 years with West syndrome (Del Toro, 2013). This study aims to provide an overview of intervention through play in children with epileptic encephalopathies, starting with knowledge of its development and ending with an intervention model for this population. [...]
El juego puede ser una herramienta ideal para estimular el desarrollo de los niños con síndrome de West entre 0 y 6 años de vida (Del Toro, 2013). Este trabajo aporta una perspectiva global de la intervención a través del juego en niños con encefalopatías epilépticas, partiendo del conocimiento de su desarrollo y terminando con un modelo de intervención con esta población. [...]
El joc pot ser una eina ideal per estimular el desenvolupament dels infants amb síndrome de West entre 0 i 6 anys de vida (Del Toro, 2013). Aquest treball aporta una perspectiva global de la intervenció a través del joc en nens amb encefalopaties epilèptiques, partint del coneixement del seu desenvolupament i arribant a un model d'intervenció per a aquesta població. [...]
2021 - 10.5565/rev/educar.1145
Educar, Vol. 57 Núm. 1 (2021) , p. 155-171 (Temas de investigación)
|
|
|
10.
|
|
guest ::
email alert
or subscribe to the 
RSS feed.
