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13 p, 585.6 KB Compartmentalized immune response in leishmaniasis : Changing patterns throughout the disease / Rodríguez-Cortés, Alhelí. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Carrillo, Eugenia. (Centro Nacional de Microbiología (Espanya)) ; Martorell, Susanna (Zoetis Inc.) ; Todolí, Felicitat (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Ojeda García, Ana (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Martínez-Flórez, Alba (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Urniza, Alicia (Zoetis Inc.) ; Moreno, Javier (Centro Nacional de Microbiología (Espanya)) ; Alberola, Jordi (Alberola i Domingo) (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Alberola, Jordi (Alberola i Domingo)
Visceral leishmaniasis (VL) is characterized by loss of T-cell responsiveness and absence of Leishmania-specific IFN-γ production by peripheral blood mononuclear cells. However, the expressions of IFN-γ and TNF-α are up-regulated in the tissues and plasma of VL patients. [...]
2016 - 10.1371/journal.pone.0155224
PloS one, Vol. 11 Núm. 5 (january 2016) , p. e0155224  

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