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23 p, 1.1 MB

The Behavioral and Psychological Symptoms of Dementia in down Syndrome Scale (BPSD-DS II) : Optimization and Further Validation / Dekker, Alain D. (Department of Practice-oriented Scientific Research (PWO). Alliade Care Group) ; Ulgiati, Aurora M. (Department of Practice-oriented Scientific Research (PWO). Alliade Care Group) ; Groen, Henk (Department of Epidemiology. University of Groningen. University Medical Center Groningen) ; Boxelaar, Vicent A. (Center for Information Technology. University of Groningen) ; Sacco, Silvia (Institut Jérôme Lejeune) ; Falquero, Ségolène (Institut Jérôme Lejeune) ; Carfi, Angelo (Policlinico Universitario Agostino Gemelli IRCCS (Roma, Itàlia)) ; Di Paola, Antonella (Department of Geriatrics. Fondazione Policlinico Universitario Gemelli Irccs) ; Benejam, Bessy (Barcelona Down Medical Center. Fundació Catalana Síndrome de Down) ; Valldeneu, Silvia (Institut d'Investigació Biomèdica Sant Pau) ; Fopma, Roelie (Department of Practice-oriented Scientific Research (PWO). Alliade Care Group) ; Oosterik, Marjo (Aveleijn) ; Hermelink, Marloes (De Twentse Zorgcentra) ; Beugelsdijk, Gonny (Ipse de Bruggen) ; Schippers, Mieke (Ipse de Bruggen) ; Henstra, Hepie (Nieuw Woelwijck) ; Scholten-Kuiper, Martine (Philadelphia Zorg) ; Willink-Vos, Judith (Severinus) ; De Ruiter, Lisa (Sherpa) ; Willems, Liesbeth (Sprank) ; Loonstra-De Jong, Anneke (Vanboeijen) ; Coppus, Antonia (Dichterbij) ; Tollenaere, Marleen (Department of Neurology and Memory Clinic. Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Onder, Graziano (Department of Cardiovascular. Endocrine-metabolic Diseases and Aging. Istituto Superiore di Sanitá) ; Rebillat, Anne-Sophie (Institut Jérôme Lejeune) ; Van Dam, Debby (Laboratory of Neurochemistry and Behavior. Department of Biomedical Sciences and Institute Born-Bunge. University of Antwerp) ; De Deyn, Peter Paul (University Hospital Antwerp (Bèlgica))
Background: People with Down syndrome (DS) are at high risk to develop Alzheimer's disease dementia (AD). Behavioral and psychological symptoms of dementia (BPSD) are common and may also serve as early signals for dementia. [...]
2021 - DOI (Digital Object Identifier)

10.3233/JAD-201427
Journal of Alzheimer's disease, Vol. 81 Núm. 4 (2021) , p. 1505-1527

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13 p, 787.1 KB

Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease / Dekker, Alain D. (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Vermeiren, Yannick (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Carmona Iragui, María (Fundació Catalana Síndrome de Down) ; Benejam, Bessy (Fundació Catalana Síndrome de Down) ; Videla Toro, Laura (Fundació Catalana Síndrome de Down) ; Gelpi, Ellen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Aerts, Tony (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Van Dam, Debby (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Fernández, Susana (Fundació Catalana Síndrome de Down) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Videla, Sebastian (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Sieben, Anne (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Martin, Jean-Jacques (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Fortea, Juan (Fundació Catalana Síndrome de Down) ; De Deyn, Peter Paul (University Hospital Antwerp (Bèlgica)) ; Universitat Autònoma de Barcelona
People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. [...]
2017 - DOI (Digital Object Identifier)

10.1016/j.dadm.2017.11.001
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 10 (november 2017) , p. 99-111

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