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Resultados globales: 4 registros encontrados en 0.02 segundos.
Artículos, Encontrados 4 registros
Artículos Encontrados 4 registros  
1.
3 p, 1.6 MB The PRALINE database : protein and Rna humAn singLe nucleotIde variaNts in condEnsates / Vandelli, Andrea (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Arnal, Magdalena (University Sapienza Rome) ; Monti, Michele (Istituto Italiano di Tecnologia) ; Fiorentino, Jonathan (Istituto Italiano di Tecnologia) ; Broglia, Laura (Istituto Italiano di Tecnologia) ; Colantoni, Alessio (University Sapienza Rome) ; Sánchez de Groot, Natalia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Armaos, Alexandros (Istituto Italiano di Tecnologia) ; Tartaglia, Gian Gaetano (Istituto Italiano di Tecnologia)
Biological condensates are membraneless organelles with different material properties. Proteins and RNAs are the main components, but most of their interactions are still unknown. Here, we introduce PRALINE, a database for the interrogation of proteins and RNAs contained in stress granules, processing bodies and other assemblies including droplets and amyloids. [...]
2023 - 10.1093/bioinformatics/btac847
Bioinformatics, Vol. 39, Num.1 (January 2023) , art. btac847  
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2.
7 p, 1.0 MB Phase Separation Drives SARS-CoV-2 Replication : A Hypothesis / Vandelli, Andrea (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Vocino, Giovanni (University of Bologna) ; Tartaglia, Gian Gaetano (Institució Catalana de Recerca i Estudis Avançats)
Identifying human proteins that interact with SARS-CoV-2 genome is important to understand its replication and to identify therapeutic strategies. Recent studies have unveiled protein interactions of SARS-COV-2 in different cell lines and through a number of high-throughput approaches. [...]
2022 - 10.3389/fmolb.2022.893067
Frontiers in Molecular Biosciences, Vol. 9 (May 2022) , art. 893067  
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3.
15 p, 1.1 MB Zooming in on protein-RNA interactions : a multi-level workflow to identify interaction partners / Colantoni, Alessio (Istituto Italiano di Tecnologia. Center for Life Nanoscience) ; Rupert, Jakob (Istituto Italiano di Tecnologia. Center for Human Technologies) ; Vandelli, Andrea (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Tartaglia, Gian Gaetano (Institució Catalana de Recerca i Estudis Avançats) ; Zacco, Elsa (Istituto Italiano di Tecnologia. Center for Human Technologies)
Interactions between proteins and RNA are at the base of numerous cellular regulatory and functional phenomena. The investigation of the biological relevance of non-coding RNAs has led to the identification of numerous novel RNA-binding proteins (RBPs). [...]
2020 - 10.1042/BST20191059
Biochemical Society Transactions, Vol. 48, Issue 4 (August 2020) , p. 1529-1543  
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4.
14 p, 2.4 MB Structural analysis of SARS-CoV-2 genome and predictions of the human interactome / Vandelli, Andrea (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Monti, Michele (Universitat Pompeu Fabra) ; Milanetti, Edoardo (Sapienza Università di Roma) ; Armaos, Alexandros (Universitat Pompeu Fabra) ; Rupert, Jakob (Istituto Italiano di Tecnologia) ; Zacco, Elsa (Istituto Italiano di Tecnologia) ; Bechara, Elias (Universitat Pompeu Fabra) ; Delli Ponti, Riccardo (Nanyang Technological University) ; Tartaglia, Gian Gaetano (Universitat Pompeu Fabra)
Specific elements of viral genomes regulate interactions within host cells. Here, we calculated the secondary structure content of >2000 coronaviruses and computed >100 000 human protein interactions with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [...]
2020 - 10.1093/nar/gkaa864
Nucleic acids research, Vol. 48, Issue 20 (November 2020) , p. 11270-11283  
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