Resultados globales: 5 registros encontrados en 0.02 segundos.
Artículos, Encontrados 5 registros
Artículos Encontrados 5 registros  
1.
11 p, 4.3 MB Antigen-specific immunotherapy combined with a regenerative drug in the treatment of experimental type 1 diabetes / Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ; Perna-Barrull, David (Institut Germans Trias i Pujol) ; Ampudia, Rosa Maria (Institut Germans Trias i Pujol) ; Gomez-Muñoz, Laia (Institut Germans Trias i Pujol) ; Pujol-Autonell, Irma (Institut Germans Trias i Pujol) ; Aguilera, Eva (Institut Germans Trias i Pujol) ; Risueño, Ruth M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Vázquez, Federico (Institut Germans Trias i Pujol) ; Vives-Pi, Marta (Institut Germans Trias i Pujol)
Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. To revert type 1 diabetes, the suppression of the autoimmune attack should be combined with a β-cell replacement strategy. [...]
2020 - 10.1038/s41598-020-76041-1
Scientific reports (Nature Publishing Group), Vol. 10 (2020) , art. 18927  
2.
14 p, 2.6 MB Repurposed analog of GLP-1 ameliorates hyperglycemia in type 1 diabetic mice through pancreatic cell reprogramming / Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Rodríguez Fernández, Silvia (Institut Germans Trias i Pujol) ; Perna-Barrull, David (Institut Germans Trias i Pujol) ; Ampudia, Rosa Maria (Institut Germans Trias i Pujol) ; Gomez-Muñoz, Laia (Institut Germans Trias i Pujol) ; Pujol-Autonell, Irma (Institut Germans Trias i Pujol) ; Aguilera, Eva (Institut Germans Trias i Pujol) ; Coma, Mireia (Anaxomics Biotech SL) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Vázquez, Federico (Institut Germans Trias i Pujol) ; Verdaguer, Joan (Universitat de Lleida. Departament de Medicina Experimental) ; Vives Pi, Marta (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas)
Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. An ideal immunotherapy should combine the blockade of the autoimmune response with the recovery of functional target cell mass. [...]
2020 - 10.3389/fendo.2020.00258
Frontiers in Endocrinology, Vol. 11 (May 2020) , art. 258  
3.
13 p, 1.5 MB Impaired Phagocytosis in Dendritic Cells From Pediatric Patients With Type 1 Diabetes Does Not Hamper Their Tolerogenic Potential / Rodríguez Fernández, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Murillo, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Villalba Felipe, Adrián (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Perna-Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Gómez Muñoz, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Aguilera, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Vázquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bel, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vives Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Type 1 diabetes (T1D) is prompted by defective immunological tolerance, an event in which dendritic cells (DCs) are crucial as immune response orchestrators. In fact, they contribute to maintaining tolerance to self-antigens, but they can also prompt an immunogenic response against them, leading to autoimmunity. [...]
2019 - 10.3389/fimmu.2019.02811
Frontiers in immunology, Vol. 10 (November 2019) , art. 2811  
4.
9 p, 859.1 KB Preclinical carotid atherosclerosis in patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes and classical type 1 diabetes / Hernández, Marta (Hospital Universitari Arnau de Vilanova) ; López, Carolina (Universitat de Lleida. Escola d'Infermeria) ; Real, Jordi (Epidemiologia i Salut Pública, Universitat International de Catalunya) ; Valls, Joan (Institut de Recerca Biomèdica de Lleida) ; Ortega Martinez de Victoria, Emilio (Hospital Clinic, CIBERehd. Department of Pathology) ; Vázquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rubinat, Esther (Universitat de Lleida. Escola d'Infermeria) ; Granado Casas, Minerva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Molí, Teresa (Hospital Universitari Arnau de Vilanova) ; Betriu, Angels (Institut de Recerca Biomèdica de Lleida) ; Lecube, Albert (Hospital Universitari Arnau de Vilanova) ; Fernández, Elvira (Hospital Universitari Arnau de Vilanova) ; Leslie, Richard David (The Blizard Institute, Barts and the London School of Medicine and Dentistry, London) ; Mauricio, Dídac (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Background: LADA is probably the most prevalent form of autoimmune diabetes. Nevertheless, there are few data about cardiovascular disease in this group of patients. The aim of this study was to investigate the frequency of carotid atherosclerotic plaques in patients with LADA as compared with patients with classic type 1 diabetes and type 2 diabetes. [...]
2017 - 10.1186/s12933-017-0576-9
Cardiovascular Diabetology, Vol. 16 Núm. 94 (2017) , p. 1-9  
5.
17 p, 2.4 MB Phosphatidylserine-liposomes promote tolerogenic features on dendritic cells in human type 1 diabetes by apoptotic mimicry / Rodriguez Fernandez, Silvia (Institut Germans Trias i Pujol) ; Pujol Autonell, Irma (Institut Germans Trias i Pujol) ; Brianso, Ferran (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Perna-Barrull, David (Institut Germans Trias i Pujol) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; García Jimeno, Sonia (Institut Català de Nanociència i Nanotecnologia) ; Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Sanchez, Alex (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Aguilera, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vazquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Verdaguer, Joan (Universitat de Lleida. Departament de Medicina Experimental) ; Maspoch Comamala, Daniel (Institució Catalana de Recerca i Estudis Avançats) ; Vives Pi, Marta (Institut Germans Trias i Pujol)
Type 1 diabetes (T1D) is a metabolic disease caused by the autoimmune destruction of insulin-producing β-cells. With its incidence increasing worldwide, to find a safe approach to permanently cease autoimmunity and allow β-cell recovery has become vital. [...]
2018 - 10.3389/fimmu.2018.00253
Frontiers in immunology, Vol. 9 (Feb. 2018) , art. 253  

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