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9 p, 1.5 MB Limited detection of human polyomaviruses in Fanconi anemia related squamous cell carcinoma / Toptan, Tuna (University of Pittsburgh, Pennsylvania, United States of America) ; Brusadelli, Marion G. (Cincinnati Children's Hospital Medical Center) ; Turpin, Brian (Cincinnati Children's Hospital Medical Center) ; Witte, David P. (Cincinnati Children's Hospital Medical Center) ; Surrallés i Calonge, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Velleuer, Eunike (Hospital Neuwerk Maria von den Aposteln, Mönchengladbach, Germany) ; Schramm, Martin (Heinrich Heine University, Düsseldorf, Germany) ; Dietrich, Ralf (Deutsche Fanconi-Anämie-Hilfe e.V., Unna-Siddinghausen, Germany) ; Brakenhoff, Ruud H. (Vrije Universiteit Amsterdam, The Netherlands) ; Moore, Patrick S. (University of Pittsburgh, Pennsylvania, United States of America) ; Chang, Yuan (University of Pittsburgh, Pennsylvania, United States of America) ; Wells, Susanne I. (Cincinnati Children's Hospital Medical Center) ; Universitat Autònoma de Barcelona
Fanconi anemia is a rare genome instability disorder with extreme susceptibility to squamous cell carcinoma of the head and neck and anogenital tract. In patients with this inherited disorder, the risk of head and neck cancer is 800-fold higher than in the general population, a finding which might suggest a viral etiology. [...]
2018 - 10.1371/journal.pone.0209235
PloS one, Vol. 13 (december 2018)  

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