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7 p, 710.9 KB |
Indications related to antidepressant prescribing in the Nivel-PCD database and the SIDIAP database
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Camacho-Arteaga, Lina (Hospital Universitari Vall d'Hebron) ;
Gardarsdottir, Helga (Utrecht University. Division of Pharmacoepidemiology and Clinical Pharmacology) ;
Ibañez, Luisa (Hospital Universitari Vall d'Hebron) ;
Souverein, Patrick (Utrecht University. Division of Pharmacoepidemiology and Clinical Pharmacology) ;
van Dijk, Liset (Netherlands Institute for Health Services Research) ;
Hek, Karin (Netherlands Institute for Health Services Research) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Ballarín, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sabaté, Mònica (Hospital Universitari Vall d'Hebron)
Antidepressant drug consumption has increased, mainly in the elderly. This trend could be explained by the use for indications other than depression. We aimed to describe the indications related to antidepressant drug new users in two primary care settings.
2022 -  10.1016/j.jad.2022.02.001
Journal of affective disorders, Vol. 303 (04 2022) , p. 131
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2.
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9 p, 611.2 KB |
Adverse Reactions to Drugs of Special Interest in a Pediatric Oncohematology Service
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Amaro-Hosey, Kristopher (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Danés Carreras, Immaculada (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vendrell Bosch, Lourdes (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alonso, Laura (Vall d'Hebron Institut d'Oncologia) ;
Renedo-Miró, Berta (Hospital Universitari Vall d'Hebron) ;
Gros, Luis (Vall d'Hebron Institut d'Oncologia) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Cereza García, Gloria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Agustí Escasany, M. Antònia (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Introduction: Drugs used in oncological diseases are frequently related to adverse drug reactions (ADR). Few studies have analyzed the toxicity of cancer treatments in children in real practice. Methods: An observational, longitudinal and prospective study has been carried out in an Oncohematology Service of a tertiary hospital. [...]
2021 - 10.3389/fphar.2021.670945
Frontiers in Pharmacology, Vol. 12 (may 2021)
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3.
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1.1 MB |
Synergism interaction between genetic polymorphisms in drug metabolizing enzymes and NSAIDs on upper gastrointestinal haemorrhage : a multicenter case-control study
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Mallah, Narmeen (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Zapata-Cachafeiro, Maruxa (CIBER en Epidemiología y Salud Pública-CIBERESP) ;
Aguirre, Carmelo (Universidad del País Vasco) ;
Ibarra-García, Eguzkiñe (Hospital Urduliz) ;
Palacios-Zabalza, Itziar (Hospital de Galdakao (Usansolo, Biscaia)) ;
Macías-García, Fernando (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Piñeiro-Lamas, María (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Ibáñez, Luisa (Hospital Universitari Vall d'Hebron) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Vendrell Bosch, Lourdes (Hospital Universitari Vall d'Hebron) ;
Martin-Arias, Luis (Universidad de Valladolid) ;
Sáinz-Gil, María (Universidad de Valladolid) ;
Velasco-González, Verónica (Universidad de Valladolid) ;
Bacariza-Cortiñas, Manuel (Centro de Saúde de Vite) ;
Salgado, Angel (University of Santiago de Compostela) ;
Estany-Gestal, Ana (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Figueiras, Adolfo (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Universitat Autònoma de Barcelona
Interindividual genetic variations contribute to differences in patients' response to drugs as well as to the development of certain disorders. Patients who use non-steroidal anti-inflammatory drugs (NSAIDs) may develop serious gastrointestinal disorders, mainly upper gastrointestinal haemorrhage (UGIH). [...]
2022 - 10.1080/07853890.2021.2016940
Annals of Medicine, Vol. 54 (february 2022) , p. 379-392
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4.
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10 p, 372.3 KB |
Polymorphisms Involved in Platelet Activation and Inflammatory Response on Aspirin-Related Upper Gastrointestinal Bleeding : A Case-Control Study
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Mallah, Narmeen (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Zapata-Cachafeiro, Maruxa (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Aguirre, Carmelo (Universidad del País Vasco) ;
Ibarra-García, Eguzkiñe (Hospital Ourduliz) ;
Palacios-Zabalza, Itziar (Hospital de Galdakao (Usansolo, Biscaia)) ;
Macías-García, Fernando (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Domínguez-Muñoz, J. Enrique (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Piñeiro-Lamas, María (Instituto de Investigación Sanitaria de Santiago) ;
Ibáñez, Luisa (Hospital Universitari Vall d'Hebron) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Vendrell Bosch, Lourdes (Hospital Universitari Vall d'Hebron) ;
Martin-Arias, Luis (Universidad de Valladolid) ;
Sáinz-Gil, María (Universidad de Valladolid) ;
Velasco-González, Verónica (Universidad de Valladolid) ;
Figueiras, Adolfo (Instituto de Investigación Sanitaria de Santiago) ;
Universitat Autònoma de Barcelona
Despite the wide benefits of aspirin and its cost-effectiveness, aspirin prescriptions have been reduced due to idiosyncratic responses in susceptible individuals. Low-dose aspirin and single-nucleotide polymorphisms (SNPs) are independently associated with increased risk of gastrointestinal hemorrhage; however, to-date, no studies investigated the SNP-aspirin interaction effect on upper gastrointestinal hemorrhage (UGIH). [...]
2020 - 10.3389/fphar.2020.00860
Frontiers in Pharmacology, Vol. 11 (june 2020)
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5.
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11 p, 1.8 MB |
Antidepressant use and stroke or mortality risk in the elderly
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Ön, Begüm Irmak (Institute for Medical Information Processing. Biometry and Epidemiology. LMU Munich) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Berger, Úrsula (Institute for Medical Information Processing. Biometry and Epidemiology. LMU Munich) ;
Sabaté, Mònica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ballarín, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Maisterra, Olga (Hospital Universitari Vall d'Hebron) ;
San-Jose, Antonio (Hospital Universitari Vall d'Hebron) ;
Ibáñez, Luisa (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Background and purpose: Current evidence on antidepressant-related stroke or mortality risk is inconsistent. Because the elderly have the highest exposure to antidepressants, the aim was to quantify their association with stroke and mortality risks in this vulnerable population. [...]
2021 - 10.1111/ene.15137
European Journal of Neurology, Vol. 29 (2021) , p. 469-477
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16 p, 1.2 MB |
Incidence of direct oral anticoagulant use in patients with nonvalvular atrial fibrillation and characteristics of users in 6 European countries (2008-2015) : A cross-national drug utilization study
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Ibáñez, Luisa (Universitat Autònoma de Barcelona) ;
Sabaté, Mònica (Universitat Autònoma de Barcelona) ;
Vidal Guitart, Xavier (Universitat Autònoma de Barcelona) ;
Ballarín, Elena (Hospital Universitari Vall d'Hebron) ;
Rottenkolber, Marietta (Klinikum der Universität München) ;
Schmiedl, Sven (Helios University Hospital Wuppertal) ;
Heeke, Andreas (AOK NORDWEST) ;
Huerta, Consuelo (Spanish Agency of Medicines and Medical Devices (AEMPS)) ;
Martin Merino, Elisa (Spanish Agency of Medicines and Medical Devices (AEMPS)) ;
Montero, Dolores (Spanish Agency of Medicines and Medical Devices (AEMPS)) ;
Leon-Muñoz, Luz María (Spanish Agency of Medicines and Medical Devices (AEMPS)) ;
Gasse, Christiane (Aarhus University) ;
Moore, Nicholas (INSERM CIC1401, Université de Bordeaux) ;
Droz, Cécile (INSERM CIC1401, Université de Bordeaux) ;
Lassalle, Régis (INSERM CIC1401, Université de Bordeaux) ;
Aakjær, Mia (University of Copenhagen) ;
Andersen, Morten (University of Copenhagen) ;
De Bruin, Marie Louise (University of Copenhagen) ;
Groenwold, Rolf (Leiden University Medical Center) ;
van den Ham, Hendrika A. (Universiteit Utrecht, David de Wiedgebouw) ;
Souverein, Patrick (Universiteit Utrecht, David de Wiedgebouw) ;
Klungel, Olaf (University Medical Center Utrecht) ;
Gardarsdottir, Helga (University of Iceland) ;
Universitat Autònoma de Barcelona ;
Hospital Universitari Vall d'Hebron
To estimate the incidence of direct oral anticoagulant drug (DOAC) use in patients with nonvalvular atrial fibrillation and to describe user and treatment characteristics in 8 European healthcare databases representing 6 European countries. [...]
2019 - 10.1111/bcp.14071
British Journal of Clinical Pharmacology, Vol. 85 (september 2019) , p. 2524-2539
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7.
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19 p, 2.6 MB |
Urinary neuropilin-1 : A predictive biomarker for renal outcome in lupus nephritis
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Torres-Salido, Maria Teresa (Hospital Quirónsalud Barcelona) ;
Sanchis, M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Solé, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Moliné, Teresa (Hospital Universitari Vall d'Hebron) ;
Vidal, Marta (Hospital Universitari Vall d'Hebron) ;
Vidal Guitart, Xavier. (Hospital Universitari Vall d'Hebron) ;
Solà, Anna (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Hotter, G. (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Ordi-Ros, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cortés-Hernández, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
2019 - 10.3390/ijms20184601
International journal of molecular sciences, Vol. 20 Núm. 18 (february 2019) , p. 4601
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5 p, 855.9 KB |
La consulta terapèutica : una eina complementària d'informació per a la individualització de la terapèutica
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Agustí Escasany, M. Antònia (Maria Antònia), (Hospital Universitari Vall d'Hebron) ;
Aguilera Martin, Cristina (Hospital Universitari Vall d'Hebron) ;
Danés Carreras, Immaculada (Hospital Universitari Vall d'Hebron) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Arnau de Bolós, José Mª (Hospital Universitari Vall d'Hebron) ;
Laporte Rosselló, Joan-Ramón (Hospital Universitari Vall d'Hebron)
En aquest article es presenten els resultats d'un treball de recerca que analitza les característiques de la demanda d'informació sobre terapéutica atesa durant els darrers quinze anys a la Fundació Institut Catalá de Farmacologia. [...]
2000
Annals de medicina, Vol. 83 Núm. 4 (2000) , p. 223-227 (Recerca autóctona, espécie a protegir)
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9.
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8 p, 208.8 KB |
CYP2C9 variants as a risk modifier of NSAID-related gastrointestinal bleeding : a case-control study
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Figueiras, Adolfo (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Estany-Gestal, Ana (Department of Preventive Medicine and Public Health, Santiago de Compostela University) ;
Aguirre, Carmelo (Hospital de Galdakao (Usansolo, Biscaia)) ;
Ruiz, Borja (Department of Pharmacology, Basque Country University School of Medicine) ;
Vidal Guitart, Xavier (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Carvajal, Alfonso (Pharmacoepidemiology Institute, University of Valladolid) ;
Salado, Inés (Pharmacoepidemiology Institute, University of Valladolid) ;
Salgado-Barreira, Angel (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Rodella, Luca (Service of Digestive Endoscopy) ;
Moretti, Ugo (University Hospital of Verona (Itàlia)) ;
Ibáñez, Luisa (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Hospital Vall d'Hebron ;
Fundació Institut Català de Farmacologia
We conducted a multicenter, case-control study in which cases were patients aged more than 18 years with a diagnosis of UGIB, and controls were matched (1 : 3) by sex, age, date of admission, and hospital. [...]
2016 - 10.1097/FPC.0000000000000186
Pharmacogenetics and Genomics, Vol. 26 (january 2016) , p. 66-73
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9 p, 383.2 KB |
Inappropriate prescribing to the oldest old patients admitted to hospital : prevalence, most frequently used medicines, and associated factors
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San-José, Antonio (Sociedad Española de Medicina Interna) ;
Agustí Escasany, M. Antònia (Maria Antònia) (Hospital Universitari Vall d'Hebron) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Formiga, Francesc (Sociedad Española de Medicina Interna) ;
Gómez-Hernández, Mercedes (Sociedad Española de Medicina Interna) ;
García, Juana (Sociedad Española de Medicina Interna) ;
López-Soto, Alfonso (Sociedad Española de Medicina Interna) ;
Ramírez-Duque, Nieves (Sociedad Española de Medicina Interna) ;
Torres, Olga H (Sociedad Española de Medicina Interna) ;
Barbé, José (Sociedad Española de Medicina Interna) ;
Universitat Autònoma de Barcelona
Scientific evidence on treatments of chronic diseases in patients 85 years old or older is very limited, as is available information on inappropriate prescription (IP) and its associated factors. The study aimed to describe medicine prescription, potentially inappropriate medicines (PIM) and potentially prescribing omissions (PPO) and their associated factors on this population. [...]
2015 - 10.1186/s12877-015-0038-8
BMC geriatrics, Vol. 15 (april 2015)
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