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13 p, 1.4 MB Activation of cGMP/Protein Kinase G Pathway in Postconditioned Myocardium Depends on Reduced Oxidative Stress and Preserved Endothelial Nitric Oxide Synthase Coupling / Inserte, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernando, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vilardosa, Úrsula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Abad, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Poncelas-Nozal, Marcos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
The cGMP/protein kinase G (PKG) pathway is involved in the cardioprotective effects of postconditioning (PoCo). Although PKG signaling in PoCo has been proposed to depend on the activation of the phosphatidylinositol 3-kinase (PI3K)/Akt cascade, recent data bring into question a causal role of reperfusion injury signaling kinase (RISK) in PoCo protection. [...]
2013 - 10.1161/JAHA.112.005975
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 2 (february 2013)  
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