Results overview: Found 6 records in 0.02 seconds.
Articles, 5 records found
Course materials, 1 records found
Articles 5 records found  
1.
4 p, 393.4 KB Copper(II) and the pathological H50Q α-synuclein mutant : environment meets genetics / Villar-Piqué, Anna (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Rossetti, Giulia (Jülich Forschungszentrum. Institut für Neurowissenschaften und Medizin) ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Carloni, Paolo (Jülich Forschungszentrum. Institut für Neurowissenschaften und Medizin) ; Fernández, Claudio O. (Max Planck Laboratory for Structural Biology, Chemistry and Molecular Biophysics of Rosario) ; Outeiro, Tiago Fleming (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Copper is one of the metals described to bind the Parkinson disease-related protein α-synuclein (aSyn), and to promote its aggregation. Although histidine at position 50 in the aSyn sequence is one of the most studied copper-anchoring sites, its precise role in copper binding and aSyn aggregation is still unclear. [...]
2017 - 10.1080/19420889.2016.1270484
Communicative & integrative Biology, Vol. 10, no. 1 (2017) , e127048  
2.
9 p, 626.3 KB Proteome response at the edge of protein aggregation / Sanchez de Groot, Natalia (MRC Laboratory of Molecular Biology) ; Gomes, Ricardo A. (Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier) ; Villar Pique, Anna (University Medical Centre Göottingen. Department of Neurodegeneration and Restorative Research) ; Madan Babu, M. (MRC Laboratory of Molecular Biology) ; Varela Coelho, Ana (Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier) ; Ventura i Zamora, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Proteins adopt defined structures and are crucial to most cellular functions. Their misfolding and aggregation is associated with numerous degenerative human disorders such as type II diabetes, Huntington's or Alzheimer's diseases. [...]
2015 - 10.1098/rsob.140221
Open biology, Vol. 5, issue 2 (Feb. 2015) , art. 140221  
3.
11 p, 1.6 MB Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors / Villar Piqué, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Ventura i Zamora, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Espargaró Colomé, Alba (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sabaté, Raimon (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sánchez de Groot, Natalia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Background: The amyloid-β peptide (Aβ42) is the main component of the inter-neuronal amyloid plaques characteristic of Alzheimer's disease (AD). The mechanism by which Aβ42 and other amyloid peptides assemble into insoluble neurotoxic deposits is still not completely understood and multiple factors have been reported to trigger their formation. [...]
2012 - 10.1186/1475-2859-11-55
Microbial cell factories, Vol. 11, N. 55 (May 2012) , p. 1-11  
4.
12 p, 2.5 MB Yeast prions form infectious amyloid inclusion bodies in bacteria / Espargaró Colomé, Alba (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura i Zamora, Salvador (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villar Piqué, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Sabaté, Raimon (Universitat de Barcelona. Departament de Fisicoquímica)
Background: Prions were first identified as infectious proteins associated with fatal brain diseases in mammals. However, fungal prions behave as epigenetic regulators that can alter a range of cellular processes. [...]
2012 - 10.1186/1475-2859-11-89
Microbial cell factories, Vol. 11, N. 89 (June 2012) , p. 1-12
2 documents
5.
9 p, 6.8 MB Amyloid-like protein inclusions in tobacco transgenic plants / Villar-Piqué, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Sabaté Lagunas, Raimon (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Lopera Ortega, Oriol (Centre de Recerca en Agrigenòmica) ; Gibert Amat, Jordi (Centre de Recerca en Agrigenòmica) ; Torné, Josep M. (Centre de Recerca en Agrigenòmica) ; Santos, Mireya (Centre de Recerca en Agrigenòmica) ; Ventura Zamora, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The formation of insoluble protein deposits in human tissues is linked to the onset of more than 40 different disorders, ranging from dementia to diabetes. In these diseases, the proteins usually self-assemble into ordered β-sheet enriched aggregates known as amyloid fibrils. [...]
2010 - 10.1371/journal.pone.0013625
PLoS one, Vol. 5, Issue 10 (October 2010) , p. e13625  

Course materials 1 records found  
1.
7 p, 152.0 KB Laboratori integrat 2 [100885] / Plana i Coll, Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; March Centelles, Pedro de ; Villar Piqué, Anna ; García Viloca, Mireia ; Roig Navarro, Ignasi ; de March Centelles, Pere ; Vallribera Massó, Adelina ; Universitat Autònoma de Barcelona. Facultat de Biociències
2010-11
Graduat o Graduada en Bioquímica [814]  

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