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7 p, 1.1 MB High-resolution fish on DNA fibers for low-copy repeats genome architecture studies / Molina, Òscar (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Blanco, Joan (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Anton, Ester (Universitat Autònoma de Barcelona. Unitat de Biologia Cel·lular) ; Vidal, Francesca (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Volpi, E.V. (University of Oxford. The Wellcome Trust Center for Human Genetics)
Low-copy repeats (LCRs) constitute 5% of the human genome. LCRs act as substrates for non-allelic homologous recombination (NAHR) leading to genomic structural variation. The aim of this study was to assess the potential of Fiber-FISH for LCRs direct visualization to support investigations of genome architecture within these challenging genomic regions. [...]
2012 - 10.1016/j.ygeno.2012.08.007
Genomics, Vol. 100, Num. 6 (December 2012) , p. 380-386  

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