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1.
12 p, 2.4 MB Interim Results from the IMPACT Study : Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers / Page, Elizabeth C. (Institute of Cancer Research) ; Bancroft, Elizabeth K. (Royal Marsden NHS Foundation Trust) ; Brook, Mark N. (Institute of Cancer Research) ; Assel, Melissa (Memorial Sloan Kettering Cancer Center) ; Hassan Al Battat, Mona (Lund University) ; Thomas, Sarah (Royal Marsden NHS Foundation Trust) ; Taylor, Natalie (Royal Marsden NHS Foundation Trust) ; Chamberlain, Anthony (Institute of Cancer Research) ; Pope, Jennifer (Institute of Cancer Research) ; Raghallaigh, Holly Ni (Institute of Cancer Research) ; Evans, D.Gareth (Central Manchester University Hospitals NHS Foundation Trust) ; Rothwell, Jeanette (Central Manchester University Hospitals NHS Foundation Trust) ; Maehle, Lovise (Oslo University Hospital (Oslo, Noruega)) ; Grindedal, Eli Marie (Oslo University Hospital (Oslo, Noruega)) ; James, Paul (The Royal Melbourne Hospital) ; Mascarenhas, Lyon (Peter MacCallum Cancer Centre) ; McKinley, Joanne (Peter MacCallum Cancer Centre) ; Side, Lucy (Princess Anne Hospital) ; Thomas, Tessy (Princess Anne Hospital) ; van Asperen, Christi (Leiden University Medical Center) ; Vasen, Hans (The Foundation for the Detection of Hereditary Cancer) ; Kiemeney, Lambertus A. (Radboud University Medical Center) ; Ringelberg, Janneke (The Foundation for the Detection of Hereditary Cancer) ; Jensen, Thomas Dyrso. (Vejle Hospital) ; Osther, Palle J.S. (Vejle Hospital) ; Helfand, Brian T. (NorthShore University HealthSystem) ; Genova, Elena (NorthShore University HealthSystem) ; Oldenburg, Rogier A. (Erasmus University Medical Center) ; Cybulski, Cezary (Pomeranian Medical University in Szczecin) ; Wokolorczyk, Dominika (Pomeranian Medical University in Szczecin) ; Ong, Kai-Ren (Birmingham Women's Hospital) ; Huber, Camilla (Birmingham Women's Hospital) ; Lam, Jimmy (Bedford Park) ; Taylor, Louise (Daw Park) ; Salinas, Monica (Hospital Universitari de Bellvitge) ; Feliubadaló, Lidia (Hospital Universitari de Bellvitge) ; Oosterwijk, Jan C. (University of Groningen) ; van Zelst-Stams, Wendy (Radboud University Medical Center) ; Cook, Jackie (Sheffield Children's Hospital (Sheffield, Regne Unit)) ; Rosario, Derek J. (Royal Hallamshire Hospital) ; Domchek, Susan (Basser Research Center. University of Pennsylvania) ; Powers, Jacquelyn (University of Pennsylvania) ; Buys, Saundra (University of Utah) ; O'Toole, Karen (University of Utah) ; Ausems, Margreet G. E. M (University Medical Centre) ; Schmutzler, Rita K. (University Hospital Cologne) ; Rhiem, Kerstin (University Hospital Cologne) ; Izatt, Louise (Guy's and St Thomas' NHS Foundation Trust) ; Tripathi, Vishakha (Guy's and St Thomas' NHS Foundation Trust) ; Teixeira, Manuel R. (Porto University) ; Cardoso, Marta (Portuguese Oncology Institute (IPO Porto)) ; Foulkes, William D. (McGill University) ; Aprikian, Armen (Research Institute of McGill University Health Centre) ; van Randeraad, Heleen (The Foundation for the Detection of Hereditary Cancer) ; Davidson, Rosemarie (Queen Elizabeth University Hospital) ; Longmuir, Mark (Queen Elizabeth University Hospital) ; Ruijs, Marielle W.G. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Helderman van den Enden, Apollonia T.J.M. (Maastricht University Medical Center) ; Adank, Muriel (Amsterdam UMC) ; Williams, Rachel (Prince of Wales Hospital (Australia)) ; Andrews, Lesley (Prince of Wales Hospital (Australia)) ; Murphy, Declan G. (Peter MacCallum Cancer Centre) ; Halliday, Dorothy (Oxford Centre for Genomic Medicine) ; Walker, Lisa (Oxford Centre for Genomic Medicine) ; Liljegren, Annelie (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Carlsson, Stefan (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Azzabi, Ashraf (Newcastle upon Tyne Hospitals) ; Jobson, Irene (Newcastle upon Tyne Hospitals) ; Morton, Catherine (The Royal Melbourne Hospital) ; Shackleton, Kylie (The Royal Melbourne Hospital) ; Snape, Katie (St George's Hospital) ; Hanson, Helen (St George's Hospital) ; Harris, Marion (Monash Health) ; Tischkowitz, Marc (University of Cambridge) ; Taylor, Amy (Cambridge University Hospitals NHS Trust) ; Kirk, Judy (Sydney Medical School) ; Susman, Rachel (Royal Brisbane & Women's Hospital) ; Chen-Shtoyerman, Rakefet (Kaplan Medical Center) ; Spigelman, Allan (The Kinghorn Cancer Centre. St Vincent's Hospital) ; Pachter, Nicholas (University of Western Australia) ; Ahmed, Munaza (NE Thames Regional Genetics Service) ; Ramon y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ; Zgajnar, Janez (Institute of Oncology) ; Brewer, Carole (Royal Devon and Exeter Hospital) ; Gadea, Neus (Hospital Universitari Vall d'Hebron) ; Brady, Angela F. (London North West University Healthcare NHS Trust) ; van Os, Theo (Academic Medical Center) ; Gallagher, David (St James's Hospital) ; Johannsson, Oskar (Landspitali University Hospital (Reykjavík, Islàndia)) ; Donaldson, Alan (St Michael's Hospital) ; Barwell, Julian (University Hospitals Leicester) ; Nicolai, Nicola (Istituto Nazionale dei Tumori) ; Friedman, Eitan (Chaim Shema Medical Center) ; Obeid, Elias (Fox Chase Cancer Center) ; Greenhalgh, Lynn (Liverpool Women's Hospital) ; Murthy, Vedana (Tata Memorial Centre) ; Copakova, Lucia (National Cancer Institute) ; Saya, Sibel (Institute of Cancer Research) ; McGrath, John (University of Exeter Medical School) ; Cooke, Peter (New Cross Hospital) ; Rønlund, Karina (Vejle Hospital) ; Richardson, Kate (Peter MacCallum Cancer Centre) ; Henderson, Alex (West Cumberland Infirmary) ; Teo, Soo H. (Subang Jaya Medical Centre) ; Arun, Banu (The University of Texas) ; Kast, Karin (Technische Universität Dresden) ; Dias, Alexander (Instituto Nacional de Cancer Jose de Alencar Gomes da Silva (INCA)) ; Aaronson, Neil K (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Ardern-Jones, Audrey (Royal Marsden NHS Foundation Trust) ; Bangma, Chris H. (Erasmus University Medical Center) ; Castro, Elena (Spanish National Cancer Research Center) ; Dearnaley, David (The Institute of Cancer Research) ; Eccles, Diana M. (The University of Southampton Medical School) ; Tricker, Karen (Central Manchester University Hospitals NHS Foundation Trust) ; Eyfjord, Jorunn (University of Iceland) ; Falconer, Alison (Imperial College Healthcare NHS Trust) ; Foster, Christopher (HCA Pathology Laboratories) ; Gronberg, Henrik (University Hospital) ; Hamdy, Freddie C. (University of Oxford) ; Stefansdottir, Vigdis (Landspitali University Hospital (Reykjavík, Islàndia)) ; Khoo, Vincent (The University of Melbourne) ; Lindeman, Geoffrey J. (The Walter and Eliza Hall Institute of Medical Research) ; Lubinski, Jan (Pomeranian Medical University in Szczecin) ; Axcrona, Karol (Akershus University Hospital) ; Mikropoulos, Christos (Medway Hospital) ; Mitra, Anita (University College London Hospitals NHS Foundation Trust) ; Moynihan, Clare (Institute of Cancer Research) ; Rennert, Gadi (Carmel Medical Center) ; Suri, Mohnish (Nottingham City Hospital) ; Wilson, Penny (Innovate UK. Polaris House) ; Dudderidge, Tim (University Hospital Southampton) ; Offman, Judith (King's College London) ; Kote-Jarai, Zsofia (Institute of Cancer Research) ; Vickers, Andrew (Memorial Sloan Kettering Cancer Center) ; Lilja, Hans (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ; Eeles, Rosalind A. (Royal Marsden NHS Foundation Trust) ; Universitat Autònoma de Barcelona
Mutations in BRCA2 cause a higher risk of early-onset aggressive prostate cancer (PrCa). The IMPACT study is evaluating targeted PrCa screening using prostate-specific-antigen (PSA) in men with germline BRCA1/2 mutations. [...]
2019 - 10.1016/j.eururo.2019.08.019
European Urology, Vol. 76 Núm. 6 (december 2019) , p. 831-842  
2.
34 p, 16.2 MB Stroke genetics informs drug discovery and risk prediction across ancestries / Mishra, Aniket (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Malik, Rainer (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Hachiya, Tsuyoshi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Jürgenson, Tuuli (University of Tartu. Institute of Mathematics and Statistics) ; Namba, Shinichi (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Posner, Daniel C. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Kamanu, Frederick K. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Koido, Masaru (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Le Grand, Quentin (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Shi, Mingyang (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; He, Yunye (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Georgakis, Marios K. (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Caro, Ilana (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Krebs, Kristi (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Liaw, Yi-Ching (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Vaura, Felix C. (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Lin, Kuang (University of Oxford. Nuffield Department of Population Health) ; Winsvold, Bendik Slagsvold (Oslo University Hospital (Oslo, Noruega)) ; Srinivasasainagendra, Vinodh (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Parodi, Livia (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Bae, Hee-Joon (Seoul National University Bundang Hospital, Seoul National University College of Medicine. Department of Neurology and Cerebrovascular Disease Center) ; Chauhan, Ganesh (Rajendra Institute of Medical Sciences) ; Chong, Michael R. (McMaster University. Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine) ; Tomppo, Liisa (Helsinki University Hospital) ; Akinyemi, Rufus (University of Ibadan. Neuroscience and Ageing Research Unit Institute for Advanced Medical Research and Training, College of Medicine) ; Roshchupkin, Gennady V. (Erasmus MC University Medical Center Rotterdam. Department of Radiology and Nuclear Medicine) ; Habib, Naomi (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Jee, Yon Ho (Harvard T. H. Chan School of Public Health. Department of Epidemiology) ; Thomassen, Jesper Qvist (Copenhagen University Hospital-Rigshospitalet. Department of Clinical Biochemistry) ; Abedi, Vida (The Pennsylvania State University. Department of Public Health Sciences, College of Medicine) ; Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ; Nygaard, Marianne (Odense University Hospital (Dinamarca)) ; Leonard, Hampton L. (Data Tecnica International) ; Yang, Chaojie (University of Virginia. Department of Biochemistry and Molecular Genetics) ; Yonova-Doing, Ekaterina (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Knol, Maria J. (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Lewis, Adam J. (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Judy, Renae L. (University of Pennsylvania. Department of Surgery) ; Ago, Tetsuro (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Amouyel, Philippe (Institut Pasteur de Lille) ; Armstrong, Nicole D. (University of Alabama at Birmingham. Department of Epidemiology) ; Bakker, Mark K. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Bartz, Traci M. (University of Washington. Department of Biostatistics) ; Bennett, David A. (Rush University Medical Center. Rush Alzheimer's Disease Center) ; Bis, Joshua C (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Bordes, Constance (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Børte, Sigrid (Oslo University Hospital. Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research and Innovation, Division of Clinical Neuroscience) ; Cain, Anael (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Ridker, Paul M. (Harvard Medical School) ; Cho, Kelly (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Chen, Zhengming (University of Oxford. MRC Population Health Research Unit) ; Cruchaga, Carlos (Washington University School of Medicine. NeuroGenomics and Informatics Center) ; Cole, John W. (University of Maryland School of Medicine. Department of Neurology) ; De Jager, Philip L (Columbia University Medical Center. Center for Translational and Computational Neuroimmunology, Department of Neurology) ; de Cid, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Endres, Matthias (partner site Berlin. German Centre for Cardiovascular Research (DZHK)) ; Ferreira, Leslie E. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Geerlings, Mirjam I. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Gasca, Natalie C. (University of Washington. Department of Biostatistics) ; Gudnason, Vilmundur (University of Iceland. Faculty of Medicine) ; Hata, Jun (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; He, Jing (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Heath, Alicia K. (Imperial College London. Department of Epidemiology and Biostatistics, School of Public Health) ; Ho, Yuk-Lam (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Havulinna, Aki S (FIMM-HiLIFE. Institute for Molecular Medicine Finland) ; Hopewell, Jemma C. (University of Oxford. Clinical Trial Service and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health) ; Hyacinth, Hyacinth I. (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Inouye, Michael (University of Cambridge. British Heart Foundation Centre of Research Excellence) ; Jacob, Mina A. (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Jeon, Christina E. (Los Angeles County Department of Public Health) ; Jern, Christina (Sahlgrenska University Hospital (Suècia)) ; Kamouchi, Masahiro (Kyushu University. Department of Health Care Administration and Management, Graduate School of Medical Sciences) ; Keene, Keith L. (East Carolina University. Department of Biology, Brody School of Medicine Center for Health Disparities) ; Kitazono, Takanari (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Kittner, Steven J. (VA Maryland Health Care System. Department of Neurology and Geriatric Research and Education Clinical Center) ; Konuma, Takahiro (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Kumar, Amit (Rajendra Institute of Medical Sciences) ; Lacaze, Paul (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Launer, Lenore Joy (National Institute on Aging, NIH. Intramural Research Program) ; Lee, Keon-Joo (Korea University Guro Hospital. Department of Neurology) ; Lepik, Kaido (University Center for Primary Care and Public Health, Lausanne, Switzerland) ; Li, Jiang (Geisinger Health System. Department of Molecular and Functional Genomics, Weis Center for Research) ; Li, Liming (Peking University Health Science Center. Department of Epidemiology and Biostatistics, School of Public Health) ; Manichaikul, Ani (University of Virginia. Center for Public Health Genomics) ; Markus, Hugh S. (University of Cambridge. Stroke Research Group, Department of Clinical Neurosciences) ; Marston, Nicholas A. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Meitinger, Thomas (German Research Center for Environmental Health. Institute of Human Genetics, Helmholtz Zentrum München) ; Mitchell, Braxton D. (Baltimore Veterans Administration Medical Center. Geriatrics Research and Education Clinical Center) ; Montellano, Felipe A. (University Hospital Würzburg. Department of Neurology) ; Morisaki, Takayuki (The University of Tokyo. Division of Molecular Pathology, Institute of Medical Sciences) ; Mosley, Thomas H. (University of Mississippi Medical Center. The MIND Center) ; Nalls, Mike A. (Data Tecnica International) ; Nordestgaard, Børge G. (University of Copenhagen. Department of Clinical Medicine) ; O'Donnell, Martin J. (NUI Galway. College of Medicine Nursing and Health Science) ; Okada, Yukinori (Osaka University. Center for Infectious Disease Education and Research (CiDER)) ; Onland-Moret, N. Charlotte (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Ovbiagele, Bruce (University of California, San Francisco. Weill Institute for Neurosciences) ; Peters, Annette (German Centre for Cardiovascular Research (DZHK), partner site Munich) ; Psaty, Bruce M. (University of Washington. Department of Health Systems and Population Health) ; Rich, Stephen S. (University of Virginia. Center for Public Health Genomics) ; Rosand, Jonathan (Massachusetts General Hospital. McCance Center for Brain Health) ; Sabatine, Marc S. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Sacco, Ralph L. (Evelyn F. McKnight Brain Institute) ; Saleheen, Danish (Columbia University. Division of Cardiology, Department of Medicine) ; Sandset, Else Charlotte (The Norwegian Air Ambulance Foundation. Research and Development) ; Salomaa, Veikko (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Sargurupremraj, Muralidharan (University of Texas Health Sciences Center. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases) ; Sasaki, Makoto (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Satizabal, Claudia L. (Framingham Heart Study) ; Schmidt, Carsten O. (University Medicine Greifswald, Institute for Community Medicine, SHIP/KEF) ; Shimizu, Atsushi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Smith, Nicholas L. (Seattle Epidemiologic Research and Information Center. Department of Veterans Affairs Office of Research and Development) ; Sloane, Kelly L. (University of Pennsylvania. Department of Neurology) ; Sutoh, Yoichi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Sun, Yan V. (Emory University Rollins School of Public Health. Department of Epidemiology) ; Tanno, Kozo (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Tiedt, Steffen (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ; Torres-Aguila, Nuria P.. (Institut d'Investigació Biomèdica Sant Pau) ; Tiwari, Hemant K. (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Trégouët, David-Alexandre (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Trompet, Stella (Leiden University Medical Center. Department of Cardiology) ; Tuladhar, Anil Man (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Tybjærg-Hansen, Anne (University of Copenhagen. Department of Clinical Medicine) ; van Vugt, Marion (University Medical Center Utrecht, Utrecht University. Division Heart & Lungs, Department of Cardiology) ; Vibo, Riina (University of Tartu. Department of Neurology and Neurosurgery) ; Verma, Shefali S. (University of Pennsylvania. Department of Pathology and Laboratory Medicine) ; Wiggins, Kerri L. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Wennberg, Patrik (Umeå University. Department of Public Health and Clinical Medicine) ; Woo, Daniel (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Wilson, Peter W. F. (Emory University School of Medicine. Department of Medicine, Division of Cardiovascular Disease) ; Xu, Huichun (University of Maryland School of Medicine. Department of Medicine) ; Yang, Qiong (Boston University School of Public Health. Department of Biostatistics) ; Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Millwood, Iona Y. (University of Oxford. MRC Population Health Research Unit) ; Gieger, Christian (German Research Center for Environmental Health. Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München) ; Ninomiya, Toshiharu (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; Grabe, Hans J. (German Center for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald) ; Jukema, J. Wouter (LUMC. Einthoven Laboratory for Experimental Vascular Medicine) ; Rissanen, Ina L. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Strbian, Daniel (Helsinki University Hospital) ; Kim, Young Jin (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Chen, Pei-Hsin (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Mayerhofer, Ernst (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Howson, Joanna M. M. (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Irvin, Marguerite R. (University of Alabama at Birmingham. Department of Epidemiology) ; Adams, Hieab (Universidad Adolfo Ibáñez. Latin American Brain Health (BrainLat)) ; Wassertheil-Smoller, Sylvia (Albert Einstein College of Medicine. Department of Epidemiology and Population Health) ; Christensen, Kaare (Odense University Hospital (Dinamarca)) ; Ikram, M. Arfan (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Rundek, Tatjana (Evelyn F. McKnight Brain Institute) ; Worrall, Bradford B. (University of Virginia. Department of Public Health Science) ; Lathrop, G. Mark (McGill Genome Centre) ; Riaz, Moeen (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Simonsick, Eleanor M. (National Institute on Aging. Longitudinal Studies Section, Translational Gerontology Branch) ; Kõrv, Janika (University of Tartu. Department of Neurology and Neurosurgery) ; França, Paulo H. C. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Zand, Ramin (The Pennsylvania State University. Department of Neurology, College of Medicine) ; Prasad, Kameshwar (Rajendra Institute of Medical Sciences) ; Frikke-Schmidt, Ruth (University of Copenhagen. Department of Clinical Medicine) ; de Leeuw, Frank-Erik (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Liman, Thomas (Carl von Ossietzky University of Oldenburg. Klinik für Neurologie) ; Haeusler, Karl Georg (University Hospital Würzburg. Department of Neurology) ; Ruigrok, Ynte M. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Heuschmann, Peter Ulrich (University Hospital Würzburg. Clinical Trial Center) ; Longstreth, W. T. (University of Washington. Department of Neurology) ; Jung, Keum Ji (Yonsei University. Institute for Health Promotion, Graduate School of Public Health) ; Bastarache, Lisa (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Paré, Guillaume (David Braley Cardiac, Vascular and Stroke Research Institute. Population Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Chasman, Daniel I. (Harvard Medical School) ; Rotter, Jerome I. (The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. The Institute for Translational Genomics and Population Sciences, Department of Pediatrics) ; Anderson, Christopher D. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Zwart, John-Anker (University of Oslo. Institute of Clinical Medicine, Faculty of Medicine) ; Niiranen, Teemu J. (Turku University Hospital. Division of Medicine) ; Fornage, Myriam (University of Texas Health Science Center at Houston. Human Genetics Center, School of Public Health) ; Liaw, Yung-Po (Chung Shan Medical University Hospital. Department of Medical Imaging) ; Seshadri, Sudha (Boston University School of Medicine. Department of Neurology) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Walters, Robin G. (University of Oxford. MRC Population Health Research Unit) ; Ruff, Christian T. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Owolabi, Mayowa O. (University of Ibadan. Department of Medicine) ; Huffman, Jennifer E. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Milani, Lili (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Kamatani, Yoichiro (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Dichgans, Martin (German Center for Neurodegenerative Diseases (DZNE)) ; Debette, Stéphanie (CHU de Bordeaux. Department of Neurology, Institute for Neurodegenerative Diseases) ; Universitat Autònoma de Barcelona
Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry ,. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. [...]
2022 - 10.1038/s41586-022-05165-3
Nature, september 2022, p. 1-15  
3.
42 p, 2.1 MB Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis / Kanoni, Stavroula (Queen Mary University of London) ; Graham, Sarah E. (University of Michigan) ; Wang, Yuxuan (Boston University School of Public Health) ; Surakka, Ida (University of Michigan) ; Ramdas, Shweta (University of Pennsylvania) ; Zhu, Xiang (Stanford University) ; Clarke, Shoa L. (Stanford University School of Medicine) ; Bhatti, Konain Fatima (Queen Mary University of London) ; Vedantam, Sailaja (Broad Institute of MIT and Harvard) ; Winkler, Thomas W. (University of Regensburg) ; Locke, Adam E. (Washington University) ; Marouli, Eirini (Queen Mary University of London) ; Zajac, Greg J. M. (University of Michigan) ; Wu, Kuan-Han H. (University of Michigan) ; Ntalla, Ioanna (Queen Mary University of London) ; Hui, Qin (Atlanta VA Health Care System) ; Klarin, Derek (Stanford University School of Medicine) ; Hilliard, Austin T. (VA Palo Alto Health Care Systems) ; Wang, Zeyuan (Atlanta VA Health Care System) ; Xue, Chao (University of Michigan) ; Thorleifsson, Gudmar (deCODE Genetics/Amgen) ; Helgadottir, Anna (deCODE Genetics/Amgen) ; Gudbjartsson, Daniel F. (University of Iceland) ; Holm, Hilma (deCODE Genetics/Amgen) ; Olafsson, Isleifur (Landspitali - National University Hospital of Iceland) ; Hwang, Mi Yeong (National Institute of Health) ; Han, Sohee (National Institute of Health) ; Akiyama, Masato (Kyushu University) ; Sakaue, Saori (The University of Tokyo) ; Terao, Chikashi (RIKEN Center for Integrative Medical Sciences) ; Kanai, Masahiro (Harvard Medical School) ; Zhou, Wei (Massachusetts General Hospital) ; Brumpton, Ben M. (St Olav's University Hospital) ; Rasheed, Humaira (University of Oslo) ; Havulinna, Aki S. (Finnish Institute for Health and Welfare) ; Veturi, Yogasudha (University of Pennsylvania) ; Pacheco, Jennifer Allen (Northwestern University) ; Rosenthal, Elisabeth A. (University of Washington) ; Lingren, Todd (Cincinnati Children's Hospital Medical Center) ; Feng, QiPing (Vanderbilt University Medical Center) ; Kullo, Iftikhar J. (Mayo Clinic) ; Narita, Akira (Tohoku Medical Megabank Organization) ; Takayama, Jun (Tohoku Medical Megabank Organization) ; Martin, Hilary C. (Wellcome Trust Sanger Institute (Regne Unit)) ; Hunt, Karen A. (Queen Mary University of London) ; Trivedi, Bhavi (Queen Mary University of London) ; Haessler, Jeffrey (Fred Hutchinson Cancer Center) ; Giulianini, Franco (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Bradford, Yuki (University of Pennsylvania) ; Miller, Jason E. (University of Pennsylvania) ; Campbell, Archie (University of Edinburgh) ; Lin, Kuang (University of Oxford) ; Millwood, Iona Y. (University of Oxford) ; Rasheed, Asif (Center for Non-Communicable Diseases) ; Hindy, George (Qatar University College of Medicine) ; Faul, Jessica D. (University of Michigan) ; Zhao, Wei (University of Michigan) ; Weir, David R. (University of Michigan) ; Turman, Constance (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Huang, Hongyan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Graff, Mariaelisa (University of North Carolina) ; Choudhury, Ananyo (University of the Witwatersrand) ; Sengupta, Dhriti (University of the Witwatersrand) ; Mahajan, Anubha (University of Oxford) ; Brown, Michael R. (The University of Texas Health Science Center at Houston) ; Zhang, Weihua (London North West University Healthcare NHS Trust) ; Yu, Ketian (University of Michigan) ; Schmidt, Ellen M. (University of Michigan) ; Pandit, Anita (University of Michigan) ; Gustafsson, S (Uppsala University) ; Yin, Xianyong (University of Michigan) ; Luan, Jian'an (University of Cambridge School of Clinical Medicine) ; Zhao, Jing-Hua (University of Cambridge) ; Matsuda, Fumihiko (Kyoto University Graduate School of Medicine) ; Jang, Hye-Mi (National Institute of Health) ; Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Medina-Gomez, Carolina (University Medical Center Rotterdam) ; Pitsillides, Achilleas (Boston University School of Public Health) ; Hottenga, Jouke Jan (Amsterdam Public Health Research Institute) ; Wood, Andrew R. (University of Exeter Medical School) ; Ji, Yingji (University of Exeter Medical School) ; Gao, Zishan (German Research Center for Environmental Health) ; Haworth, Simon (University of Bristol) ; Yousri, Noha A. (Alexandria University) ; Mitchell, Ruth E. (University of Bristol) ; Chai, Jin Fang (National University of Singapore and National University Health System) ; Aadahl, Mette (University of Copenhagen) ; Bjerregaard, Anne A. (Bispebjerg and Frederiksberg Hospital) ; Yao, Jie (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Manichaikul, Ani (University of Virginia) ; Hwu, Chii-Min (Taipei Veterans General Hospital) ; Hung, Yi-Jen (National Defense Medical Center) ; Warren, Helen R. (Queen Mary University of London) ; Ramirez, Julia (Universidad de Zaragoza) ; Bork-Jensen, Jette (University of Copenhagen) ; Kårhus, Line L. (Bispebjerg and Frederiksberg Hospital) ; Goel, Anuj (University of Oxford) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Noordam, Raymond (Leiden University Medical Center) ; Mauro, Pala (Consiglio Nazionale Delle Ricerche) ; Matteo, Floris (Università Degli Studi Di Sassari) ; McDaid, Aaron F. (Swiss Institute of Bioinformatics) ; Marques-Vidal, Pedro (Lausanne University Hospital) ; Wielscher, Matthias (Imperial College London) ; Trompet, Stella (Leiden University Medical Center) ; Sattar, Naveed (BHF Glasgow Cardiovascular Research Centre) ; Møllehave, Line T. (Bispebjerg and Frederiksberg Hospital) ; Munz, Matthias (University of Lübeck) ; Zeng, Lingyao (Partner Site Munich Heart Alliance) ; Huang, Jianfeng (Fuwai Hospital) ; Yang, Bin (Fuwai Hospital) ; Poveda, Alaitz (Lund University Diabetes Center) ; Kurbasic, Azra (Lund University Diabetes Center) ; Lamina, Claudia (German Chronic Kidney Disease Study) ; Forer, Lukas (German Chronic Kidney Disease Study) ; Scholz, Markus (University of Leipzig) ; Galesloot, Tessel E. (Radboud University Medical Center) ; Bradfield, Jonathan Paul (Quantinuum Research LLC) ; Ruotsalainen, Sanni E. (University of Helsinki) ; Daw, E. Warwick (Washington University School of Medicine) ; Zmuda, Joseph M. (University of Pittsburgh) ; Mitchell, Jonathan S. (Affiliated Institute of the University of Lübeck) ; Fuchsberger, Christian (Affiliated Institute of the University of Lübeck) ; Christensen, Henry (Lillebaelt Hospital) ; Brody, Jennifer A. (University of Washington) ; Vazquez-Moreno, Miguel (Centro Medico Nacional Siglo XXI) ; Feitosa, Mary F. (Washington University School of Medicine) ; Wojczynski, Mary K. (Washington University School of Medicine) ; Wang, Zhe (The Charles Bronfman Institute for Personalized Medicine) ; Preuss, Michael H. (The Charles Bronfman Institute for Personalized Medicine) ; Mangino, Massimo (NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust) ; Christofidou, Paraskevi (King's College London) ; Verweij, Niek (University of Groningen) ; Benjamins, Jan W. (University of Groningen) ; Engmann, Jorgen (University College London) ; Tsao, Noah L. (University of Pennsylvania) ; Verma, Anurag (University of Pennsylvania) ; Slieker, Roderick C. (Leiden University Medical Center) ; Lo, Ken Sin (Montreal Université de Montréal) ; Zilhao, Nuno R. (Icelandic Heart Association) ; Le, Phuong (University of Toronto at Mississauga) ; Kleber, Marcus E. (SYNLAB MVZ Humangenetik Mannheim GmbH) ; Delgado, Graciela E. (Heidelberg University) ; Huo, Shaofeng (University of Chinese Academy of Sciences) ; Ikeda, Daisuke D. (Tokushima Research Institute) ; Iha, Hiroyuki (Tokushima Research Institute) ; Yang, Jian (The University of Queensland) ; Liu, Jun (University Medical Center Rotterdam) ; Demirkan, Ayşe (University of Surrey) ; Leonard, Hampton L. (Data Tecnica International) ; Marten, Jonathan (University of Edinburgh) ; Frank, Mirjam (University of Duisburg-Essen) ; Schmidt, Börge (University of Duisburg-Essen) ; Smyth, Laura J. (Queen's University of Belfast) ; Cañadas-Garre, Marisa (Instituto de Investigación Biosanitaria de Granada) ; Wang, Chaolong (Genome Institute of Singapore) ; Nakatochi, Masahiro (Nagoya University Graduate School of Medicine) ; Wong, Andrew (MRC Unit for Lifelong Health and Ageing at UCL) ; Hutri-Kähönen, Nina (Tampere University) ; Sim, Xueling (National University of Singapore and National University Health System) ; Xia, Rui (University of Texas Health Science Center at Houston) ; Huerta-Chagoya, Alicia (Instituto de Investigaciones Biomédicas (Mèxic)) ; Fernandez-Lopez, Juan Carlos (Instituto Nacional de Medicina Genómica) ; Lyssenko, Valeriya (University of Bergen) ; Nongmaithem, Suraj S. (Academy of Scientific and Innovative Research (AcSIR)) ; Bayyana, Swati (Academy of Scientific and Innovative Research (AcSIR)) ; Stringham, Heather M. (University of Michigan.) ; Irvin, Marguerite R. (University of Alabama at Birmingham) ; Oldmeadow, Christopher (Hunter Medical Research Institute) ; Kim, Han-Na (SAIHST, Sungkyunkwan University) ; Ryu, Seungho (Kangbuk Samsung Hospital) ; Timmers, Paul R. H. J. (University of Edinburgh) ; Arbeeva, Liubov (University of North Carolina) ; Dorajoo, Rajkumar (Duke-NUS Medical School) ; Lange, Leslie A. (University of Colorado) ; Prasad, Gauri (CSIR-Human Resource Development Centre) ; Lorés-Motta, Laura (Radboud University Nijmegen Medical Center) ; Pauper, Marc (Radboud University Nijmegen Medical Center) ; Long, Jirong (Vanderbilt University Medical Center) ; Li, Xiaohui (Harbor-UCLA Medical Center) ; Theusch, Elizabeth (University of California San Francisco) ; Takeuchi, Fumihiko (National Center for Global Health and Medicine) ; Spracklen, Cassandra N. (University of Massachusetts-Amherst) ; Loukola, Anu (University of Helsinki) ; Bollepalli, Sailalitha (University of Helsinki) ; Warner, Sophie C. (Glenfield Hospital) ; Wang, Ya Xing (Beijing Institute of Ophthalmology) ; Wei, Wen B. (Beijing Tongren Eye Center) ; Nutile, Teresa (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" - CNR) ; Ruggiero, Daniela (IRCCS Neuromed) ; Sung, Yun Ju (Washington University) ; Chen, Shufeng (Fuwai Hospital) ; Liu, Fangchao (Fuwai Hospital) ; Yang, Jingyun (Rush University Medical Center) ; Kentistou, Katherine A. (University of Edinburgh) ; Banas, Bernhard (University Hospital Regensburg) ; Nardone, Giuseppe Giovanni (IRCCS Burlo Garofolo) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Bielak, Lawrence F. (University of Michigan) ; Smith, Jennifer A. (University of Michigan) ; Hebbar, Prashantha (Dasman Diabetes Institute) ; Farmaki, Aliki-Eleni (University College London) ; Hofer, Edith (Medical University of Graz) ; Lin, Maoxuan (Massachusetts General Hospital Cancer Center) ; Concas, Maria Pina (IRCCS Burlo Garofolo) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research) ; van der Most, Peter J (University of Groningen) ; Pitkänen, Niina (University of Turku and Turku University Hospital) ; Cade, Brian E. (Harvard Medical School) ; van der Laan, Sander W (University Medical Center Utrecht) ; Chitrala, Kumaraswamy Naidu (University of Houston-Sugarland) ; Weiss, Stefan (University of Greifswald and University Medicine Greifswald) ; Bentley, Amy R. (National Human Genome Research Institute) ; Doumatey, Ayo P. (National Human Genome Research Institute) ; Adeyemo, Adebowale A. (National Human Genome Research Institute) ; Lee, Jong Young (Soonchunhyang Mirai Medical Center 173) ; Petersen, Eva R. B. (Hospital of Southern Jutlandy and Immunology) ; Nielsen, Aneta A. (Lillebaelt Hospital) ; Choi, Hyeok Sun (Hallym University) ; Nethander, Maria (University of Gothenburg) ; Freitag-Wolf, Sandra (Kiel University) ; Southam, Lorraine (Institute of Translational Genomics) ; Rayner, Nigel W. (University of Oxford) ; Wang, Carol A (University of Newcastle) ; Lin, Shih-Yi (National Defense Medical Center) ; Wang, Jun-Sing (National Yang Ming Chiao Tung University) ; Couture, Christian (Université Laval) ; Lyytikäinen, Leo-Pekka (Finnish Cardiovascular Research Center - Tampere) ; Nikus, Kjell (Finnish Cardiovascular Research Center - Tampere) ; Cuellar-Partida, Gabriel (University of Queensland Diamantina Institute) ; Vestergaard, Henrik (Bornholms Hospital) ; Hidalgo, Bertha (University of Alabama at Birmingham) ; Giannakopoulou, Olga (Queen Mary University of London) ; Cai, Qiuyin (Vanderbilt University Medical Center) ; Obura, Morgan O. (Amsterdam Public Health Research Institute) ; van Setten, Jessica (University Medical Center Utrecht) ; Li, Xiaoyin (Case Western Reserve University) ; Liang, Jingjing (Case Western Reserve University) ; Tang, Hua (Stanford University School of Medicine Stanford) ; Terzikhan, Natalie (University Medical Center Rotterdam) ; Shin, Jae Hun (Hallym University) ; Jackson, Rebecca D. (Ohio State University) ; Reiner, Alexander P. (University of Washington) ; Martin, Lisa Warsinger (George Washington University) ; Chen, Zhengming (University of Oxford) ; Li, Liming (Peking University Health Science Center) ; Kawaguchi, Takahisa (Kyoto University Graduate School of Medicine) ; Thiery, Joachim (University Hospital Leipzig) ; Bis, Joshua C (University of Washington) ; Launer, Lenore J. (National Institute On Aging) ; Li, Huaixing (University of Chinese Academy of Sciences) ; Nalls, Mike A. (Data Tecnica International) ; Raitakari, Olli T. (Turku University Hospital (Finlàndia)) ; Ichihara, Sahoko (Jichi Medical University School of Medicine) ; Wild, Sarah H. (University of Edinburgh) ; Nelson, Christopher P. (NIHR Leicester Biomedical Research Centre) ; Campbell, Harry (University of Edinburgh) ; Jäger, Susanne (German Center for Diabetes Research (DZD)) ; Nabika, Toru (Shimane University School of Medicine) ; Al-Mulla, Fahd (Dasman Diabetes Institute) ; Niinikoski, Harri (University of Turku) ; Braund, Peter S. (NIHR Leicester Biomedical Research Centre) ; Kolcic, Ivana (University of Split School of Medicine) ; Kovacs, Peter (University of Leipzig Medical Center) ; Giardoglou, Tota (Harokopio University) ; Katsuya, Tomohiro (Osaka University Graduate School of Medicine) ; de Kleijn, Dominique (University Medical Center Utrecht) ; de Borst, Gert J. (University Medical Center Utrecht) ; Kim, Eung Kweon (Yonsei University College of Medicine) ; Adams, Hieab H. H. (Universidad Adolfo Ibáñez) ; Ikram, M. Arfan (University Medical Center Rotterdam) ; Zhu, X (Case Western Reserve University) ; Asselbergs, Folkert W. (University Medical Center Utrecht) ; Kraaijeveld, Adriaan O. (University Medical Center Utrecht) ; Beulens, Joline W. J. (University Medical Centre Utrecht) ; Shu, Xiao-Ou (Vanderbilt University Medical Center) ; Rallidis, Loukianos S. (National and Kapodistrian University of Athens) ; Pedersen, Oluf (University of Copenhagen) ; Hansen, Torben (University of Copenhagen) ; Mitchell, Paul (University of Sydney) ; Hewitt, Alex W. (University of Melbourne) ; Kähönen, Mika (Tampere University) ; Pérusse, Louis (Institute of Nutrition and Functional Foods (INAF)) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Tönjes, Anke (University of Leipzig Medical Center) ; Chen, Yii Der Ida (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Pennell, Craig E. (University of Newcastle) ; Mori, Trevor A. (The University of Western Australia) ; Lieb, Wolfgang (Kiel University) ; Franke, Andre (Kiel University) ; Ohlsson, Claes (Sahlgrenska University Hospital (Suècia)) ; Mellström, Dan (University of Gothenburg) ; Cho, Yoon Shin (Hallym University) ; Lee, Hyejin (EwhaWomans University School of Medicine) ; Yuan, Jian-Min (University of Pittsburgh) ; Koh, Woon-Puay (Singapore Institute for Clinical Sciences) ; Rhee, Sang Youl (Kyung Hee University School of Medicine) ; Woo, Jeong-Taek (Kyung Hee University School of Medicine) ; Heid, Iris M. (University of Regensburg) ; Stark, Klaus J. (University of Regensburg) ; Zimmermann, Martina E. (University of Regensburg) ; Völzke, Henry (University Medicine Greifswald) ; Homuth, Georg (University of Greifswald and University Medicine Greifswald) ; Evans, Michele K. (National Institute On Aging Intramural Research Program) ; Zonderman, Alan B. (National Institute On Aging Intramural Research Program) ; Polasek, Ozren (Algebra University College) ; Pasterkamp, Gerard (University Medical Center Utrecht) ; Hoefer, Imo E. (University Medical Center Utrecht) ; Redline, Susan (Harvard Medical School) ; Pahkala, Katja (University of Turku) ; Oldehinkel, Albertine J. (University of Groningen) ; Snieder, Harold (University Medical Center Groningen) ; Biino, Ginevra (National Research Council of Italy) ; Schmidt, Reinhold (Medical University of Graz) ; Schmidt, Helena (Medical University of Graz) ; Bandinelli, Stefania (Local Health Unit Toscana Centro) ; Dedoussis, George (Harokopio University of Athens) ; Thanaraj, Thangavel Alphonse (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Kardia, Sharon L. R. (University of Michigan) ; Peyser, Patricia A. (University of Michigan) ; Kato, Norihiro (National Center for Global Health and Medicine) ; Schulze, Matthias B. (University of Potsdam) ; Girotto, Giorgia (University of Trieste) ; Böger, Carsten A. (KfH Kidney Center Traunstein) ; Jung, Bettina (KfH Kidney Center Traunstein) ; Joshi, Peter K. (University of Edinburgh) ; Bennett, David A. (Rush University Medical Center) ; De Jager, Philip L. (Columbia University Medical Center) ; Lu, Xiangfeng (Fuwai Hospital) ; Mamakou, Vasiliki (Dromokaiteio Psychiatric Hospital) ; Brown, Morris (Queen Mary University of London) ; Caulfield, Mark J. (Queen Mary University of London) ; Munroe, Patricia B. (Queen Mary University of London) ; Guo, Xiuqing (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Ciullo, Marina (IRCCS Neuromed) ; Jonas, Jost B. (Privatpraxis Prof Jonas Und Dr Panda-Jonas) ; Samani, Nilesh J. (NIHR Leicester Biomedical Research Centre) ; Kaprio, Jaakko (University of Helsinki) ; Pajukanta, Päivi (University of California) ; Tusié-Luna, Teresa (Instituto de Investigaciones Biomédicas UNAM/ Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ; Aguilar-Salinas, Carlos Alberto (Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ; Adair, Linda S. (University of North Carolina) ; Bechayda, Sonny Augustin (University of San Carlos) ; de Silva, H. Janaka (University of Kelaniya) ; Wickremasinghe, Ananda R. (University of Kelaniya) ; Krauss, Ronald M. (Children's Hospital Oakland Research Institute) ; Wu, Jer-Yuarn (Institute of Biomedical Sciences) ; Zheng, Wei (Vanderbilt University Medical Center) ; Hollander, Anneke Iden (Radboud University Nijmegen Medical Center) ; Bharadwaj, Dwaipayan (Jawaharlal Nehru University) ; Correa, Adolfo (University of Mississippi Medical Center) ; Wilson, James G. (University of Mississippi Medical Center) ; Lind, Lars (Uppsala University) ; Heng, Chew-Kiat (Yong Loo Lin School of Medicine) ; Nelson, Amanda E. (University of North Carolina) ; Golightly, Yvonne M. (University of North Carolina) ; Wilson, James F. (University of Edinburgh) ; Penninx, Brenda (Vrije Universiteit Amsterdam) ; Kim, Hyung-Lae (Ewha Womans University) ; Attia, John (University of Newcastle) ; Scott, Rodney J. (University of Newcastle) ; Rao, D. C. (Washington University School of Medicine) ; Arnett, Donna K. (University of South Carolina) ; Hunt, Steven C. (University of Utah) ; Walker, Mark (Institute of Cellular Medicine (Diabetes)) ; Koistinen, Heikki A. (Minerva Foundation Institute for Medical Research) ; Chandak, Giriraj R. (JSS Academy of Higher Education and Research) ; Mercader, Josep M. (Harvard Medical School) ; Costanzo, Maria C. (Broad Institute of MIT and Harvard) ; Jang, Dongkeun (Broad Institute of MIT and Harvard) ; Burtt, Noël P. (Broad Institute of MIT and Harvard) ; Villalpando, Clicerio Gonzalez (InstitutoNacional de Salud Publica Y Centro de Estudios en Diabetes (Mèxic)) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Fornage, Myriam (University of Texas Health Science at Houston) ; Tai, EShyong (Yong Loo Lin School of Medicine) ; van Dam, Rob M. (Milken Institute School of Public Health) ; Lehtimäki, Terho (Finnish Cardiovascular Research Center - Tampere) ; Chaturvedi, Nish (MRC Unit for Lifelong Health and Ageing at UCL) ; Yokota, Mitsuhiro (Kurume University School of Medicine) ; Liu, Jianjun (Genome Institute of Singapore) ; Reilly, Dermot F. (Merck Sharp & Dohme Corp.. Genetics) ; McKnight, Amy Jayne (Queen's University of Belfast) ; Kee, Frank (Queen's University of Belfast) ; Jöckel, Karl-Heinz (University of Duisburg-Essen) ; McCarthy, Mark I. (University of Oxford) ; Palmer, Colin N. A. (University of Dundee) ; Vitart, Veronique (University of Edinburgh) ; Hayward, Caroline (University of Edinburgh) ; Simonsick, Eleanor (National Institute On Aging) ; van Duijn, Cornelia M. (University Medical Center Rotterdam) ; Jin, Zi-Bing (Wenzhou Medical University) ; Qu, Jia (Wenzhou Medical University) ; Hishigaki, Haretsugu (Tokushima Research Institute) ; Lin, Xu (University of Chinese Academy of Sciences) ; März, Winfried (Medical University of Graz) ; Gudnason, Vilmundur (University of Iceland) ; Tardif, Jean-Claude (Université de Montréal) ; Lettre, Guillaume (Université de Montréal) ; Hart, Leen M.'t (Amsterdam Public Health Research Institute) ; Elders, Petra J. M. (Amsterdam Public Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Kumari, Meena (University of Essex) ; Kivimaki, Mika (University College London) ; van der Harst, Pim (Utrecht University) ; Spector, Tim D. (King's College London) ; Loos, Ruth J. F. (Icahn School of Medicine at Mount Sinai) ; Province, Michael A. (Washington University School of Medicine) ; Parra, Esteban J. (University of Toronto at Mississauga) ; Cruz, Miguel (Centro Medico Nacional Siglo XXI) ; Psaty, Bruce M. (University of Washington) ; Brandslund, Ivan (University of Southern Denmark) ; Pramstaller, Peter P. (Affiliated Institute of the University of Lübeck) ; Rotimi, Charles N. (Center for Research On Genomics and Global Health) ; Christensen, Kaare (University of Southern Denmark) ; Ripatti, Samuli (Broad Institute of MIT and Harvard) ; Widén, Elisabeth (University of Helsinki) ; Hakonarson, Hakon (The University of Pennsylvania Perelman School of Medicine) ; Grant, Struan F. A. (Children's Hospital of Philadelphia (Pennsilvània)) ; Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ; de Graaf, Jacqueline (Radboud University Medical Center) ; Loeffler, Markus (University of Leipzig) ; Kronenberg, Florian (German Chronic Kidney Disease Study (Alemanya)) ; Gu, Dongfeng (Southern University of Science and Technology) ; Erdmann, Jeanette (University Heart Center Lübeck) ; Schunkert, Heribert (Partner Site Munich Heart Alliance) ; Franks, Paul W. (Lund University Diabetes Centre) ; Linneberg, Allan (University of Copenhagen) ; Jukema, J. Wouter (Netherlands Heart Institute) ; Khera, Amit V. (Verve Therapeutics) ; Männikkö, Minna (Northern Finland Birth Cohorts) ; Jarvelin, Marjo-Riitta (University of Oulu) ; Kutalik, Zoltan (Swiss Institute of Bioinformatics) ; Francesco, Cucca (University of Sassari) ; Mook-Kanamori, Dennis O. (Leiden University Medical Center) ; van Dijk, Ko Willems (Leiden University Medical Center) ; Watkins, Hugh (University of Oxford) ; Strachan, David P. (University of London) ; Grarup, Niels (University of Copenhagen) ; Sever, Peter (Imperial College London) ; Poulter, Neil (Imperial College London) ; Chuang, Lee-Ming (National Taiwan University Hospital (Taipei, Taiwan)) ; Rotter, Jerome I. (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Dantoft, Thomas M. (Bispebjerg and Frederiksberg Hospital) ; Karpe, Fredrik (NIHR Oxford Biomedical Research Centre) ; Neville, Matt J. (NIHR Oxford Biomedical Research Centre) ; Timpson, Nicholas J. (University of Bristol) ; Cheng, Ching-Yu (Duke-NUS Medical School) ; Wong, Tien-Yin (Duke-NUS Medical School) ; Khor, Chiea Chuen (Genome Institute of Singapore) ; Li, Hengtong (Singapore Eye Research Institute) ; Sabanayagam, Charumathi (Duke-NUS Medical School) ; Peters, Annette (German Center for Diabetes Research (DZD)) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Hattersley, Andrew T. (University of Exeter) ; Pedersen, Nancy L. (Karolinska Institutet (Estocolm, Suècia)) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia)) ; Boomsma, Dorret I. (Amsterdam Public Health Research Institute) ; Willemsen, Allegonda H. M. (Amsterdam Public Health Research Institute) ; Cupples, LAdrienne (US National Institutes of Health) ; van Meurs, Joyce B. J. (University Medical Center Rotterdam) ; Ghanbari, Mohsen (Mashhad University of Medical Sciences) ; Gordon-Larsen, Penny (University of North Carolina) ; Huang, Wei (Chinese National Human Genome Center at Shanghai) ; Kim, Young Jin (National Institute of Health) ; Tabara, Yasuharu (Kyoto University Graduate School of Medicine) ; Wareham, Nicholas J. (University of Cambridge School of Clinical Medicine) ; Langenberg, Claudia (Berlin Institute of Health at Charité - Universitätsmedizin) ; Zeggini, Eleftheria (Helmholtz Zentrum München - German Research Center for Environmental Health) ; Kuusisto, Johanna (University of Eastern Finland and Kuopio University Hospital) ; Laakso, Markku (University of Eastern Finland and Kuopio University Hospital) ; Ingelsson, Erik (Stanford University) ; Abecasis, Goncalo (Regeneron Pharmaceuticals) ; Chambers, John C. (Imperial College London) ; Kooner, Jaspal S. (Imperial College London) ; de Vries, Paul S. (The University of Texas Health Science Center at Houston) ; Morrison, Alanna C. (The University of Texas Health Science Center at Houston) ; Hazelhurst, Scott (University of the Witwatersrand) ; Ramsay, Michèle (University of the Witwatersrand) ; North, Kari E. (University of North Carolina) ; Daviglus, Martha (University of Illinois College of Medicine) ; Kraft, Peter (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Martin, Nicholas G. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Whitfield, John B. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Abbas, Shahid (Faisalabad Institute of Cardiology) ; Saleheen, Danish (Columbia University Irving Medical Center) ; Walters, Robin G. (University of Oxford) ; Holmes, Michael V. (Oxford University Hospitals) ; Black, Corri (University of Aberdeen) ; Smith, Blair H. (University of Dundee) ; Baras, Aris (Regeneron Pharmaceuticals) ; Justice, Anne E. (Geisinger Health) ; Buring, Julie E. (Harvard Medical School) ; Ridker, Paul M. (Harvard Medical School) ; Chasman, Daniel I. (Harvard Medical School) ; Kooperberg, Charles (Fred Hutchinson Cancer Center) ; Tamiya, Gen (Tohoku University) ; Yamamoto, Masayuki (Tohoku University) ; van Heel, David A (Queen Mary University of London) ; Trembath, Richard C. (King's College London) ; Wei, Wei-Qi (Vanderbilt University Medical Center) ; Jarvik, Gail P. (University of Washington) ; Namjou, Bahram (Cincinnati Children's Hospital Medical Center) ; Hayes, M. Geoffrey (Northwestern University) ; Ritchie, Marylyn D. (University of Pennsylvania) ; Jousilahti, Pekka (Finnish Institute for Health and Welfare) ; Salomaa, Veikko (Finnish Institute for Health and Welfare) ; Hveem, Kristian (St Olav's University Hospital) ; Åsvold, Bjørn Olav (St Olav's University Hospital) ; Kubo, Michiaki (RIKEN Center for Integrative Medical Sciences) ; Kamatani, Yoichiro (The University of Tokyo) ; Okada, Yukinori (The University of Tokyo) ; Murakami, Yoshinori (The University of Tokyo) ; Kim, Bong-Jo (National Institute of Health) ; Thorsteinsdottir, Unnur (University of Iceland) ; Stefansson, Kari (The University of Manchester) ; Zhang, Jifeng (University of Michigan) ; Chen, YEugene (University of Michigan) ; Ho, Yuk-Lam (VA Boston Healthcare System) ; Lynch, Julie A. (University of Massachusetts) ; Rader, Daniel J. (University of Pennsylvania) ; Tsao, Philip S. (Stanford University School of Medicine) ; Chang, Kyong-Mi (University of Pennsylvania Perelman School of Medicine) ; Cho, Kelly (Brigham Women's Hospital) ; O'Donnell, Christopher J. (Brigham Women's Hospital) ; Gaziano, John M. (Brigham Women's Hospital) ; Wilson, Peter W. F. (Emory University School of Medicine) ; Frayling, Timothy M. (University of Exeter Medical School) ; Hirschhorn, Joel N. (Harvard Medical School) ; Kathiresan, Sekar (Harvard Medical School) ; Mohlke, Karen L. (University of North Carolina) ; Sun, Yan V. (Atlanta VA Health Care System) ; Morris, Andrew P. (The University of Manchester) ; Boehnke, Michael (University of Michigan) ; Brown, Christopher D. (University of Pennsylvania) ; Natarajan, Pradeep (Massachusetts General Hospital) ; Deloukas, Panos (King Abdulaziz University) ; Willer, Cristen J. (University of Michigan) ; Assimes, Themistocles (Stanford University School of Medicine. Cardiovascular Institute) ; Peloso, Gina M (Boston University School of Public Health. Department of Biostatistics) ; Universitat Autònoma de Barcelona
Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery. [...]
2022 - 10.1186/s13059-022-02837-1
Genome biology, Vol. 23 (december 2022)  
4.
1 p, 647.1 KB Publisher Correction : Stroke genetics informs drug discovery and risk prediction across ancestries / Mishra, Aniket (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Malik, Rainer (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Hachiya, Tsuyoshi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Jürgenson, Tuuli (University of Tartu. Institute of Mathematics and Statistics) ; Namba, Shinichi (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Posner, Daniel C. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Kamanu, Frederick K. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Koido, Masaru (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Le Grand, Quentin (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Shi, Mingyang (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; He, Yunye (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Georgakis, Marios K. (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Caro, Ilana (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Krebs, Kristi (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Liaw, Yi-Ching (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Vaura, Felix C. (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Lin, Kuang (University of Oxford. Nuffield Department of Population Health) ; Winsvold, Bendik Slagsvold (Oslo University Hospital (Oslo, Noruega)) ; Srinivasasainagendra, Vinodh (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Parodi, Livia (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Bae, Hee-Joon (Seoul National University Bundang Hospital, Seoul National University College of Medicine. Department of Neurology and Cerebrovascular Disease Center) ; Chauhan, Ganesh (Rajendra Institute of Medical Sciences) ; Chong, Michael R. (McMaster University. Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine) ; Tomppo, Liisa (Helsinki University Hospital (Finlàndia)) ; Akinyemi, Rufus (University of Ibadan. Neuroscience and Ageing Research Unit Institute for Advanced Medical Research and Training, College of Medicine) ; Roshchupkin, Gennady V. (Erasmus MC University Medical Center Rotterdam. Department of Radiology and Nuclear Medicine) ; Habib, Naomi (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Jee, Yon Ho (Harvard T. H. Chan School of Public Health. Department of Epidemiology) ; Thomassen, Jesper Qvist (Copenhagen University Hospital-Rigshospitalet. Department of Clinical Biochemistry) ; Abedi, Vida (The Pennsylvania State University. Department of Public Health Sciences, College of Medicine) ; Cárcel-Márquez, Jara (Universitat Autònoma de Barcelona. Departament de Medicina) ; Nygaard, Marianne (Odense University Hospital (Dinamarca)) ; Leonard, Hampton L. (Data Tecnica International) ; Yang, Chaojie (University of Virginia. Department of Biochemistry and Molecular Genetics) ; Yonova-Doing, Ekaterina (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Knol, Maria J. (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Lewis, Adam J. (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Judy, Renae L. (University of Pennsylvania. Department of Surgery) ; Ago, Tetsuro (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Amouyel, Philippe (Institut Pasteur de Lille) ; Armstrong, Nicole D. (University of Alabama at Birmingham. Department of Epidemiology) ; Bakker, Mark K. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Bartz, Traci M. (University of Washington. Department of Biostatistics) ; Bennett, David A. (Rush University Medical Center. Rush Alzheimer's Disease Center) ; Bis, Joshua C. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Bordes, Constance (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Børte, Sigrid (Oslo University Hospital. Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research and Innovation, Division of Clinical Neuroscience) ; Cain, Anael (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Ridker, Paul M. (Harvard Medical School) ; Cho, Kelly (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Chen, Zhengming (University of Oxford. MRC Population Health Research Unit) ; Cruchaga, Carlos (Washington University School of Medicine. NeuroGenomics and Informatics Center) ; Cole, John W. (University of Maryland School of Medicine. Department of Neurology) ; De Jager, Philip L (Columbia University Medical Center. Center for Translational and Computational Neuroimmunology, Department of Neurology) ; de Cid, Rafael (Institut Germans Trias i Pujol) ; Endres, Matthias (partner site Berlin. German Centre for Cardiovascular Research (DZHK)) ; Ferreira, Leslie E. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Geerlings, Mirjam I. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Gasca, Natalie C. (University of Washington. Department of Biostatistics) ; Gudnason, Vilmundur (University of Iceland. Faculty of Medicine) ; Hata, Jun (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; He, Jing (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Heath, Alicia K. (Imperial College London. Department of Epidemiology and Biostatistics, School of Public Health) ; Ho, Yuk-Lam (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Havulinna, Aki S. (FIMM-HiLIFE. Institute for Molecular Medicine Finland) ; Hopewell, Jemma C. (University of Oxford. Clinical Trial Service and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health) ; Hyacinth, Hyacinth I. (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Inouye, Michael (University of Cambridge. British Heart Foundation Centre of Research Excellence) ; Jacob, Mina A. (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Jeon, Christina E. (Los Angeles County Department of Public Health) ; Jern, Christina (Sahlgrenska University Hospital (Suècia)) ; Kamouchi, Masahiro (Kyushu University. Department of Health Care Administration and Management, Graduate School of Medical Sciences) ; Keene, Keith L. (East Carolina University. Department of Biology, Brody School of Medicine Center for Health Disparities) ; Kitazono, Takanari (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Kittner, Steven J. (VA Maryland Health Care System. Department of Neurology and Geriatric Research and Education Clinical Center) ; Konuma, Takahiro (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Kumar, Amit (Rajendra Institute of Medical Sciences) ; Lacaze, Paul (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Launer, Lenore Joy (National Institute on Aging, NIH. Intramural Research Program) ; Lee, Keon-Joo (Korea University Guro Hospital. Department of Neurology) ; Lepik, Kaido (University Center for Primary Care and Public Health, Lausanne, Switzerland) ; Li, Jiang (Geisinger Health System. Department of Molecular and Functional Genomics, Weis Center for Research) ; Li, Liming (Peking University Health Science Center. Department of Epidemiology and Biostatistics, School of Public Health) ; Manichaikul, Ani (University of Virginia. Center for Public Health Genomics) ; Markus, Hugh S. (University of Cambridge. Stroke Research Group, Department of Clinical Neurosciences) ; Marston, Nicholas A. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Meitinger, Thomas (German Research Center for Environmental Health. Institute of Human Genetics, Helmholtz Zentrum München) ; Mitchell, Braxton D. (Baltimore Veterans Administration Medical Center. Geriatrics Research and Education Clinical Center) ; Montellano, Felipe A. (University Hospital Würzburg. Department of Neurology) ; Morisaki, Takayuki (The University of Tokyo. Division of Molecular Pathology, Institute of Medical Sciences) ; Mosley, Thomas H. (University of Mississippi Medical Center. The MIND Center) ; Nalls, Mike A. (Data Tecnica International) ; Nordestgaard, Børge G. (University of Copenhagen. Department of Clinical Medicine) ; O'Donnell, Martin J. (NUI Galway. College of Medicine Nursing and Health Science) ; Okada, Yukinori (Osaka University. Center for Infectious Disease Education and Research (CiDER)) ; Onland-Moret, N. Charlotte (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Ovbiagele, Bruce (University of California, San Francisco. Weill Institute for Neurosciences) ; Peters, Annette (German Centre for Cardiovascular Research (DZHK), partner site Munich) ; Psaty, Bruce M. (University of Washington. Department of Health Systems and Population Health) ; Rich, Stephen S. (University of Virginia. Center for Public Health Genomics) ; Rosand, Jonathan (Massachusetts General Hospital. McCance Center for Brain Health) ; Sabatine, Marc S. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Sacco, Ralph L. (Evelyn F. McKnight Brain Institute) ; Saleheen, Danish (Columbia University. Division of Cardiology, Department of Medicine) ; Sandset, Else Charlotte (The Norwegian Air Ambulance Foundation. Research and Development) ; Salomaa, Veikko (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Sargurupremraj, Muralidharan (University of Texas Health Sciences Center. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases) ; Sasaki, Makoto (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Satizabal, Claudia L. (Framingham Heart Study) ; Schmidt, Carsten O. (University Medicine Greifswald, Institute for Community Medicine, SHIP/KEF) ; Shimizu, Atsushi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Smith, Nicholas L. (Seattle Epidemiologic Research and Information Center. Department of Veterans Affairs Office of Research and Development) ; Sloane, Kelly L. (University of Pennsylvania. Department of Neurology) ; Sutoh, Yoichi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Sun, Yan V. (Emory University Rollins School of Public Health. Department of Epidemiology) ; Tanno, Kozo (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Tiedt, Steffen (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ; Torres-Aguila, Nuria P.. (Institut d'Investigació Biomèdica Sant Pau) ; Tiwari, Hemant K. (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Trégouët, David-Alexandre (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Trompet, Stella (Leiden University Medical Center. Department of Cardiology) ; Tuladhar, Anil Man (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Tybjærg-Hansen, Anne (University of Copenhagen. Department of Clinical Medicine) ; van Vugt, Marion (University Medical Center Utrecht, Utrecht University. Division Heart & Lungs, Department of Cardiology) ; Vibo, Riina (University of Tartu. Department of Neurology and Neurosurgery) ; Verma, Shefali S. (University of Pennsylvania. Department of Pathology and Laboratory Medicine) ; Wiggins, Kerri L. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Wennberg, Patrik (Umeå University. Department of Public Health and Clinical Medicine) ; Woo, Daniel (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Wilson, Peter W. F. (Emory University School of Medicine. Department of Medicine, Division of Cardiovascular Disease) ; Xu, Huichun (University of Maryland School of Medicine. Department of Medicine) ; Yang, Qiong (Boston University School of Public Health. Department of Biostatistics) ; Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Millwood, Iona Y. (University of Oxford. MRC Population Health Research Unit) ; Gieger, Christian (German Research Center for Environmental Health. Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München) ; Ninomiya, Toshiharu (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; Grabe, Hans J. (German Center for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald) ; Jukema, J. Wouter (LUMC. Einthoven Laboratory for Experimental Vascular Medicine) ; Rissanen, Ina L. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Strbian, Daniel (Helsinki University Hospital (Finlàndia)) ; Kim, Young Jin (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Chen, Pei-Hsin (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Mayerhofer, Ernst (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Howson, Joanna M. M. (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Irvin, Marguerite R. (University of Alabama at Birmingham. Department of Epidemiology) ; Adams, Hieab (Universidad Adolfo Ibáñez) ; Wassertheil-Smoller, Sylvia (Albert Einstein College of Medicine. Department of Epidemiology and Population Health) ; Christensen, Kaare (Odense University Hospital (Dinamarca)) ; Ikram, M. Arfan (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Rundek, Tatjana (Evelyn F. McKnight Brain Institute) ; Worrall, Bradford B. (University of Virginia. Department of Public Health Science) ; Lathrop, G. Mark (McGill Genome Centre) ; Riaz, Moeen (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Simonsick, Eleanor M. (National Institute on Aging. Longitudinal Studies Section, Translational Gerontology Branch) ; Kõrv, Janika (University of Tartu. Department of Neurology and Neurosurgery) ; França, Paulo H. C. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Zand, Ramin (The Pennsylvania State University. Department of Neurology, College of Medicine) ; Prasad, Kameshwar (Rajendra Institute of Medical Sciences) ; Frikke-Schmidt, Ruth (University of Copenhagen. Department of Clinical Medicine) ; de Leeuw, Frank-Erik (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Liman, Thomas (Carl von Ossietzky University of Oldenburg. Klinik für Neurologie) ; Haeusler, Karl Georg (University Hospital Würzburg. Department of Neurology) ; Ruigrok, Ynte M. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Heuschmann, Peter Ulrich (University Hospital Würzburg. Clinical Trial Center) ; Longstreth, W. T. (University of Washington. Department of Neurology) ; Jung, Keum Ji (Yonsei University. Institute for Health Promotion, Graduate School of Public Health) ; Bastarache, Lisa (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Paré, Guillaume (David Braley Cardiac, Vascular and Stroke Research Institute. Population Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Chasman, Daniel I. (Harvard Medical School) ; Rotter, Jerome I. (The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. The Institute for Translational Genomics and Population Sciences, Department of Pediatrics) ; Anderson, Christopher D. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Zwart, John-Anker (University of Oslo. Institute of Clinical Medicine, Faculty of Medicine) ; Niiranen, Teemu J. (Turku University Hospital. Division of Medicine) ; Fornage, Myriam (University of Texas Health Science Center at Houston. Human Genetics Center, School of Public Health) ; Liaw, Yung-Po (Chung Shan Medical University Hospital. Department of Medical Imaging) ; Seshadri, Sudha (Boston University School of Medicine. Department of Neurology) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Walters, Robin G. (University of Oxford. MRC Population Health Research Unit) ; Ruff, Christian T. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Owolabi, Mayowa O. (University of Ibadan. Department of Medicine) ; Huffman, Jennifer E. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Milani, Lili (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Kamatani, Yoichiro (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Dichgans, Martin (German Center for Neurodegenerative Diseases (DZNE)) ; Debette, Stéphanie (CHU de Bordeaux. Department of Neurology, Institute for Neurodegenerative Disease) ; Universitat Autònoma de Barcelona
2022 - 10.1038/s41586-022-05492-5
Nature, Vol. 612 (november 2022) , p. E7  
5.
58 p, 1.4 MB The power of genetic diversity in genome-wide association studies of lipids / Graham, Sarah E. (University of Michigan. Department of Internal Medicine) ; Chang, Kyong-Mi (Corporal Michael J. Crescenz VA Medical Center) ; Cho, Kelly (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; O'Donnell, Christopher J. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Gaziano, John M. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Wilson, Peter (Emory University School of Medicine) ; Rotimi, Charles (Center for Research on Genomics and Global Health. National Human Genome Research Institute. National Institutes of Health) ; Hazelhurst, Scott (University of the Witwatersrand. School of Electrical and Information Engineering) ; Ramsay, Michele (University of the Witwatersrand) ; Trembath, Richard C. (King's College London) ; van Heel, David A (Queen Mary University of London) ; Tamiya, Gen (Tohoku Medical Megabank Organization. Tohoku University) ; Yamamoto, Masayuki (Tohoku Medical Megabank Organization. Tohoku University) ; Kim, Bong-Jo (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Mohlke, Karen L (Department of Genetics. University of North Carolina) ; Frayling, Timothy M. (Genetics of Complex Traits. University of Exeter Medical School. University of Exeter) ; Hirschhorn, Joel N. (Departments of Pediatrics and Genetics. Harvard Medical School) ; Kathiresan, Sekar (Center for Genomic Medicine. Department of Medicine. Massachusetts General Hospital) ; Boehnke, Michael (Department of Biostatistics and Center for Statistics Genetics. University of Michigan) ; Natarajan, Pradeep (Cardiovascular Research Center and Center for Genomic Medicine. Massachusetts General Hospital) ; Peloso, Gina M (Department of Biostatistics. Boston University School of Public Health) ; Brown, Christopher D. (Department of Genetics. Perelman School of Medicine. University of Pennsylvania) ; Morris, Andrew P. (University College London. Centre for Adolescent Rheumatology Versus Arthritis) ; Assimes, Themistocles (Stanford University School of Medicine. Cardiovascular Institute) ; Deloukas, Panos (King Abdulaziz University) ; Sun, Yan V. (Atlanta VA Health Care System) ; Willer, Cristen J. (Department of Human Genetics. University of Michigan) ; Clarke, Shoa L. (Department of Medicine. Division of Cardiovascular Medicine. Stanford University School of Medicine) ; Wu, Kuan-Han H. (Department of Computational Medicine and Bioinformatics. University of Michigan) ; Kanoni, Stavroula (Queen Mary University of London) ; Zajac, Greg J. M. (University of Michigan) ; Ramdas, Shweta (University of Pennsylvania) ; Surakka, Ida (University of Michigan) ; Ntalla, Ioanna (Queen Mary University of London) ; Vedantam, Sailaja (Medical and Population Genetics. Broad Institute) ; Winkler, Thomas W. (Department of Genetic Epidemiology. University of Regensburg) ; Locke, Adam E. (McDonnell Genome Institute and Department of Medicine. Washington University) ; Marouli, Eirini (Queen Mary University of London) ; Hwang, Mi Yeong (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Han, Sohee (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Narita, Akira (Tohoku Medical Megabank Organization. Tohoku University) ; Choudhury, Ananyo (Sydney Brenner Institute for Molecular Bioscience. Faculty of Health Sciences. University of the Witwatersrand) ; Bentley, Amy R (Center for Research on Genomics and Global Health. National Human Genome Research Institute. National Institutes of Health) ; Ekoru, Kenneth (Center for Research on Genomics and Global Health. National Human Genome Research Institute. National Institutes of Health) ; Verma, Anurag (Department of Genetics. Perelman School of Medicine. University of Pennsylvania) ; Trivedi, Bhavi (Blizard Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; Martin, Hilary C. (Wellcome Trust Sanger Institute (Regne Unit)) ; Hunt, Karen A. (Blizard Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; Hui, Qin (Atlanta VA Health Care System) ; Klarin, Derek (Program in Medical and Population Genetics. Broad Institute of MIT and Harvard) ; Zhu, Xiang (Stanford University. Department of Statistics) ; Thorleifsson, Gudmar (deCODE genetics/Amgen) ; Helgadottir, Anna (deCODE genetics/Amgen) ; Gudbjartsson, Daniel F. (School of Engineering and Natural Sciences. University of Iceland) ; Holm, Hilma (deCODE genetics/Amgen) ; Olafsson, Isleifur (Department of Clinical Biochemistry. Landspitali-National University Hospital of Iceland) ; Akiyama, Masato (Department of Ophthalmology. Graduate School of Medical Sciences. Kyushu University) ; Sakaue, Saori (Department of Allergy and Rheumatology. Graduate School of Medicine. The University of Tokyo) ; Terao, Chikashi (Laboratory for Statistical and Translational Genetics. RIKEN Center for Integrative Medical Sciences) ; Kanai, Masahiro (Harvard Medical School. Department of Biomedical Informatics) ; Zhou, Wei (Broad Institute of MIT and Harvard) ; Brumpton, Ben M. (St Olavs Hospital. Trondheim University Hospital) ; Rasheed, Humaira (MRC Integrative Epidemiology Unit. University of Bristol) ; Ruotsalainen, Sanni E. (University of Helsinki) ; Havulinna, Aki S. (Finnish Institute for Health and Welfare) ; Veturi, Yogasudha (University of Pennsylvania. Perelman School of Medicine) ; Feng, QiPing (Vanderbilt University Medical Center) ; Rosenthal, Elisabeth A. (University of Washington. Department of Medicine) ; Lingren, Todd (Cincinnati Children's Hospital Medical Center) ; Pacheco, Jennifer Allen (Center for Genetic Medicine. Northwestern University) ; Pendergrass, Sarah A. (Genentech) ; Haessler, Jeffrey (Fred Hutchinson Cancer Research Center. Division of Public Health Sciences) ; Giulianini, Franco (Division of Preventive Medicine. Brigham and Women's Hospital) ; Bradford, Yuki (Department of Genetics. Institute for Biomedical Informatics. Perelman School of Medicine. University of Pennsylvania) ; Miller, Jason E. (Department of Genetics. Institute for Biomedical Informatics. Perelman School of Medicine. University of Pennsylvania) ; Campbell, Archie (University of Edinburgh) ; Lin, Kuang (University of Oxford. Nuffield Department of Population Health) ; Millwood, Iona Y. (University of Oxford. Nuffield Department of Population Health) ; Hindy, George (Qatar University College of Medicine) ; Rasheed, Asif (Center for Non-Communicable Diseases) ; Faul, Jessica D. (University of Michigan. Institute for Social Research) ; Zhao, Wei (University of Michigan. School of Public Health) ; Weir, David R (University of Michigan. Institute for Social Research) ; Turman, Constance (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Huang, Hongyan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Graff, Mariaelisa (University of North Carolina. Department of Epidemiology) ; Mahajan, Anubha (University of Oxford. Wellcome Centre for Human Genetics) ; Brown, Michael R. (The University of Texas Health Science Center at Houston) ; Zhang, Weihua (Imperial College Healthcare NHS Trust) ; Yu, Ketian (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Schmidt, Ellen M. (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Pandit, Anita (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Gustafsson, Stefan (Department of Medical Sciences. Molecular Epidemiology and Science for Life Laboratory. Uppsala University) ; Yin, Xianyong (Department of Biostatistics. Center for Statistical Genetics. University of Michigan) ; Luan, Jian'an (MRC Epidemiology Unit. University of Cambridge School of Clinical Medicine) ; Zhao, Jing-Hua (Cardiovascular Epidemiology Unit. Department of Public Health and Primary Care. University of Cambridge Strangeways Research Laboratory) ; Matsuda, Fumihiko (Center for Genomic Medicine. Kyoto University Graduate School of Medicine) ; Jang, Hye-Mi (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Yoon, Kyungheon (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Medina-Gomez, Carolina (Department of Epidemiology. Erasmus MC. University Medical Center Rotterdam) ; Pitsillides, Achilleas (Department of Biostatistics. Boston University School of Public Health) ; Hottenga, Jouke Jan (Amsterdam Public Health. VU Medical Center Amsterdam) ; Willemsen, Gonneke (Amsterdam Public Health Research Institute. VU Medical Center Amsterdam) ; Wood, Andrew R. (Genetics of Complex Traits. University of Exeter Medical School. University of Exeter) ; Ji, Yingji (Genetics of Complex Traits. University of Exeter Medical School. University of Exeter) ; Gao, Zishan (Institute of Epidemiology. Helmholtz Zentrum München. German Research Center for Environmental Health) ; Haworth, Simon (Bristol Dental School. University of Bristol) ; Mitchell, Ruth E. (Population Health Sciences. Bristol Medical School. University of Bristol) ; Chai, Jin-Fang (Saw Swee Hock School of Public Health. National University of Singapore and National University Health System) ; Aadahl, Mette (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Yao, Jie (The Institute for Translational Genomics and Population Sciences. Department of Pediatrics. Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Manichaikul, Ani (University of Virginia. Center for Public Health Genomics) ; Warren, Helen R. (NIHR Barts Cardiovascular Biomedical Research Centre. Barts and The London School of Medicine and Dentistry. Queen Mary University of London) ; Ramírez, Julia (William Harvey Research Institute. Barts and The London School of Medicine and Dentistry. John Vane Science Centre. Queen Mary University of London) ; Bork-Jensen, Jette (University of Copenhagen) ; Kårhus, Line L. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Goel, Anuj (University of Oxford. Radcliffe Department of Medicine) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Noordam, Raymond (Leiden University Medical Center) ; Sidore, Carlo (Institute for Genetic and Biomedical Research. Italian National Council of Research (IRGB CNR)) ; Fiorillo, Edoardo (Institute for Genetic and Biomedical Research. Italian National Council of Research (IRGB CNR)) ; McDaid, Aaron F. (Swiss Institute of Bioinformatics) ; Marques-Vidal, Pedro (Lausanne University Hospital) ; Wielscher, Matthias (Department of Epidemiology and Biostatistics. MRC-PHE Centre for Environment and Health. School of Public Health. Imperial College London) ; Trompet, Stella (Leiden University Medical Center) ; Sattar, Naveed (BHF Glasgow Cardiovascular Research Centre. Faculty of Medicine) ; Møllehave, Line T. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Thuesen, Betina H. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Munz, Matthias (Department of Periodontology and Synoptic Dentistry. Berlin Institute of Health. Institute for Dental and Craniofacial Sciences) ; Zeng, Lingyao (Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK). Partner site Munich Heart Alliance) ; Huang, Jianfeng (Chinese Academy of Medical Sciences) ; Yang, Bin (Chinese Academy of Medical Sciences) ; Poveda, Alaitz (Lund University Diabetes Centre) ; Kurbasic, Azra (Lund University Diabetes Centre) ; Lamina, Claudia (German Chronic Kidney Disease Study) ; Forer, Lukas (German Chronic Kidney Disease Study) ; Scholz, Markus (LIFE Research Centre for Civilization Diseases. University of Leipzig) ; Galesloot, Tessel E (Radboud University Medical Center. Radboud Institute for Health Sciences) ; Bradfield, Jonathan Paul (Quantinuum Research) ; Daw, E. Warwick (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Zmuda, Joseph M (Department of Epidemiology. University of Pittsburgh) ; Mitchell, Jonathan S. (Institute for Biomedicine. Eurac Research. Affiliated Institute of the University of Lübeck) ; Fuchsberger, Christian (Institute for Biomedicine. Eurac Research. Affiliated Institute of the University of Lübeck) ; Christensen, Henry (Department of Clinical Biochemistry. Lillebaelt Hospital) ; Brody, Jennifer A. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Feitosa, Mary (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Wojczynski, Mary K. (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Preuss, Michael (The Charles Bronfman Institute for Personalized Medicine. Icahn School of Medicine at Mount Sinai) ; Mangino, Massimo (NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust) ; Christofidou, Paraskevi (Department of Twin Research and Genetic Epidemiology. King's College London) ; Verweij, Niek (Department of Cardiology. University Medical Center Groningen. University of Groningen) ; Benjamins, Jan W (Department of Cardiology. University Medical Center Groningen. University of Groningen) ; Engmann, Jorgen (Department of Epidemiology and Public Health. University College London) ; Kember, Rachel L. (Department of Psychiatry. University of Pennsylvania) ; Slieker, Roderick C. (Department of Cell and Chemical Biology. Leiden University Medical Center) ; Lo, Ken S. (Montreal Heart Institute) ; Zilhao, Nuno R. (Icelandic Heart Association) ; Le, Phuong (Department of Anthropology. University of Toronto at Mississauga) ; Kleber, Marcus E. (Synlab MVZ Humangenetik Mannheim) ; Delgado, Graciela E. (University of Heidelberg. Vth Department of Medicine) ; Huo, Shsofeng (Shanghai Institute of Nutrition and Health. University of Chinese Academy of Sciences. Chinese Academy of Sciences) ; Ikeda, Daisuke D. (Biomedical Technology Research Center. Tokushima Research Institute. Otsuka Pharmaceutical) ; Iha, Hiroyuki (Biomedical Technology Research Center. Tokushima Research Institute. Otsuka Pharmaceutical) ; Yang, Jian (Department of Neurological Sciences. Rush University Medical Center) ; Liu, Jun (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Leonard, Hampton L. (Data Tecnica International) ; Marten, Jonathan (MRC Human Genetics Unit. Institute of Genetics and Cancer. University of Edinburgh. Western General Hospital) ; Schmidt, Börge (Institute for Medical Informatics. Biometrie and Epidemiology. University of Duisburg-Essen) ; Arendt, Marina (Department of Computer Science. University of Applied Sciences and Arts Dortmund) ; Smyth, Laura J. (Centre for Public Health. Queen's University of Belfast) ; Cañadas-Garre, Marisa (Centre for Public Health. Queen's University of Belfast) ; Wang, Chaolong (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Nakatochi, Masahiro (Public Health Informatics Unit. Department of Integrated Health Sciences. Nagoya University Graduate School of Medicine) ; Wong, Andrew (MRC Unit for Lifelong Health and Ageing at UCL) ; Hutri-Kähönen, Nina (Department of Pediatrics. Faculty of Medicine and Health Technology. Tampere University) ; Sim, Xueling (Saw Swee Hock School of Public Health. National University of Singapore and National University Health System) ; Xia, Rui (Brown Foundation Institute of Molecular Medicine. McGovern Medical School. University of Texas Health Science Center at Houston) ; Huerta-Chagoya, Alicia (Departamento de Medicina Genómica y Toxicología Ambiental. Instituto de Investigaciones Biomédicas. UNAM. Ciudad de Mexico) ; Fernandez-Lopez, Juan Carlos (Departamento de Genómica Computacional. Instituto Nacional de Medicina Genómica. Ciudad de Mexico) ; Lyssenko, Valeriya (Lund University Diabetes Center. Lund University) ; Ahmed, Meraj (Genomic Research on Complex Diseases (GRC Group). CSIR-Centre for Cellular and Molecular Biology) ; Jackson, Anne U. (Department of Biostatistics and Center for Statistics Genetics. University of Michigan) ; Irvin, Marguerite R. (Epidemiology. School of Public Health. University of Alabama at Birmingham) ; Oldmeadow, Christopher (Hunter Medical Research Institute) ; Kim, Han-Na (Department of Clinical Research Design and Evaluation. SAIHST. Sungkyunkwan University) ; Ryu, Seungho (Sungkyunkwan University School of Medicine) ; Timmers, Paul R. H. J. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Arbeeva, Liubov (University of North Carolina. Thurston Arthritis Research Center) ; Dorajoo, Rajkumar (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Lange, Leslie A. (Division of Biomedical Informatics and Personalized Medicine. Department of Medicine. Anschutz Medical Campus. University of Colorado. Denver) ; Chai, Xiaoran (Department of Ophthalmology. National University of Singapore and National University Health System) ; Prasad, Gauri (Academy of Scientific and Innovative Research. CSIR-Institute of Genomics and Integrative Biology Campus) ; Lorés-Motta, Laura (Departments of Ophthalmology and Human Genetics. Radboud University Nijmegen Medical Center) ; Pauper, Marc (Departments of Ophthalmology and Human Genetics. Radboud University Nijmegen Medical Center) ; Long, Jirong (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; Li, Xiaohui (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Theusch, Elisabeth (Department of Pediatrics. University of California. San Francisco) ; Takeuchi, Fumihiko (National Center for Global Health and Medicine) ; Spracklen, Cassandra N. (Department of Biostatistics and Epidemiology. University of Massachusetts-Amherst) ; Loukola, Anu (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Bollepalli, Sailalitha (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Warner, Sophie C. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Wang, Ya Xing (Beijing Tongren Eye Center. Beijing Tongren Hospital. Capital Medical University) ; Wei, Wen B. (Beijing Tongren Eye Center. Beijing Tongren Hospital. Capital Medical University) ; Nutile, Teresa (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso"-CNR) ; Ruggiero, Daniela (IRCCS Neuromed. Pozzilli) ; Sung, Yun Ju (Department of Psychiatry. Washington University) ; Hung, Yi-Jen (Division of Endocrinology and Metabolism. Tri-Service General Hospital Songshan Branch) ; Chen, Shufeng (Chinese Academy of Medical Sciences) ; Liu, Fangchao (Chinese Academy of Medical Sciences) ; Yang, Jingyun (Department of Neurological Sciences. Rush University Medical Center) ; Kentistou, Katherine A. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Gorski, Mathias (Department of Nephrology. University Hospital Regensburg) ; Brumat, Marco (Department of Medicine. Surgery and Health Sciences. University of Trieste) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Bielak, Lawrence F. (Department of Epidemiology. School of Public Health. University of Michigan) ; Smith, Jennifer A. (Department of Epidemiology. School of Public Health. University of Michigan) ; Hebbar, Prashantha (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Farmaki, Aliki-Eleni (Department of Population Science and Experimental Medicine. University College London) ; Hofer, Edith (Institute for Medical Informatics. Statistics and Documentation. Medical University of Graz) ; Lin, Maoxuan (Department of Bioinformatics and Genomics. University of North Carolina at Charlotte) ; Xue, Chao (Department of Internal Medicine. Division of Cardiology. University of Michigan) ; Zhang, Jifeng (Department of Internal Medicine. Division of Cardiology. University of Michigan) ; Concas, Maria Pina (Institute for Maternal and Child Health. IRCCS Burlo Garofolo) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research. National Research Council of Italy. UOS of Sassari) ; van der Most, Peter J (Department of Epidemiology. University Medical Center Groningen. University of Groningen) ; Pitkänen, Niina (Centre for Population Health Research. University of Turku and Turku University Hospital) ; Cade, Brian E (Division of Sleep Medicine. Harvard Medical School) ; Lee, Jiwon (Sleep Medicine and Circadian Disorders. Brigham and Women's Hospital) ; van der Laan, Sander W (University Medical Center Utrecht) ; Chitrala, Kumaraswamy Naidu (Laboratory of Epidemiology and Population Science. National Institute on Aging Intramural Research Program. NIH Biomedical Research Center. NIA) ; Weiss, Stefan (University Medicine Greifswald) ; Zimmermann, Martina E (University of Regensburg. Department of Genetic Epidemiology) ; Lee, Jong Young (Oneomics) ; Choi, Hyeok Sun (Department of Biomedical Science. Hallym University) ; Nethander, Maria (Bioinformatics Core Facility. Sahlgrenska Academy. University of Gothenburg) ; Freitag-Wolf, Sandra (Institute of Medical Informatics and Statistics. Kiel University) ; Southam, Lorraine (Wellcome Trust Sanger Institute (Regne Unit)) ; Rayner, Nigel W. (Oxford Centre for Diabetes Endocrinology and Metabolism) ; Wang, Carol A (School of Medicine and Public Health. College of Health. Medicine and Wellbeing. University of Newcastle) ; Lin, Shih Yi (School of Medicine. National Defense Medical Center) ; Wang, Jun-Sing (Department of Medicine. School of Medicine. National Yang-Ming University) ; Couture, Christian (Department of Kinesiology. Université Laval) ; Lyytikäinen, Leo-Pekka (Department of Clinical Chemistry. Finnish Cardiovascular Research Center-Tampere. Faculty of Medicine and Health Technology. Tampere University) ; Nikus, Kjell (Department of Cardiology. Finnish Cardiovascular Research Center-Tampere. Faculty of Medicine and Health Technology. Tampere University) ; Cuellar-Partida, Gabriel (University of Queensland Diamantina Institute. Translational Research Institute) ; Vestergaard, Henrik (Department of Medicine. Bornholms Hospital) ; Hildalgo, Bertha (School of Public Health. University of Alabama at Birmingham) ; Giannakopoulou, Olga (William Harvey Research Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; Cai, Qiuyin (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; Obura, Morgan O. (Amsterdam UMC. Department of Epidemiology and Biostatistics. Amsterdam Public Health Research Institute) ; van Setten, Jessica (University Medical Center Utrecht) ; Li, Xiaoyin (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Schwander, Karen (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Terzikhan, Natalie (Department of Epidemiology. Erasmus MC. University Medical Center Rotterdam) ; Shin, Jae Hun (Department of Biomedical Science. Hallym University) ; Jackson, Rebecca D. (Division of Endocrinology. Ohio State University) ; Reiner, Alewxander P. (Department of Epidemiology. University of Washington) ; Martin, Lisa W. (School of Medicine and Health Sciences. George Washington University) ; Chen, Zhengming (Medical Research Council Population Health Research Unit. Nuffield Department of Population Health. University of Oxford) ; Li, Liming (Peking University Health Science Center) ; Highland, Heather M. (Department of Epidemiology. University of North Carolina) ; Young, Kristin L. (Department of Epidemiology. University of North Carolina) ; Kawaguchi, Takahisa (Center for Genomic Medicine. Kyoto University Graduate School of Medicine) ; Thiery, Joachim (Institute for Laboratory Medicine. University Hospital Leipzig) ; Bis, Joshua C (Cardiovascular Health Research Unit. Department of Medicine. University of Washington) ; Nadkarni, Girish N. (The Charles Bronfman Institute for Personalized Medicine. Icahn School of Medicine at Mount Sinai) ; Launer, Lenore Joy (Laboratory of Epidemiology and Population Sciences. National Institute on Aging. NIH) ; Li, Huaixing (Shanghai Institute of Nutrition and Health. University of Chinese Academy of Sciences. Chinese Academy of Sciences) ; Nalls, Mike A. (Data Tecnica International) ; Raitakari, Olli T. (Department of Clinical Physiology and Nuclear Medicine. Turku University Hospital) ; Ichihara, Sahoko (Department of Environmental and Preventive Medicine. Jichi Medical University School of Medicine) ; Wild, Sarah (Centre for Population Health Sciences. Usher Institute. University of Edinburgh) ; Nelson, Christopher P. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Campbell, Harry (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Jäger, Susanne (German Center for Diabetes Research (DZD)) ; Nabika, Toru (Department of Functional Pathology. Shimane University School of Medicine) ; Al-Mulla, Fahd (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Niinikoski, Harri (Department of Physiology. University of Turku) ; Braund, Peter S. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Kolcic, Ivana (Faculty of Medicine. University of Split) ; Kovacs, Peter (Medical Department III-Endocrinology. Nephrology. Rheumatology. University of Leipzig Medical Center) ; Giardoglou, Tota (Department of Nutrition-Dietetics. Harokopio University. Eleftheriou Venizelou) ; Katsuya, Tomohiro (Department of Geriatric and General Medicine. Osaka University Graduate School of Medicine) ; Bhatti, Konain Fatima (William Harvey Research Institute. Barts and the London School of Medicine and Dentistry. Queen Mary University of London) ; de Kleijn, Dominique (University Medical Center Utrecht) ; de Borst, Gert J. (University Medical Center Utrecht) ; Kim, Eung Kweon (Corneal Dystrophy Research Institute. Department of Ophthalmology. Yonsei University College of Medicine) ; Adams, Hieab H. H. (Department of Radiology and Nuclear Medicine. Erasmus MC. University Medical Center Rotterdam) ; Ikram, M. Arfan (Erasmus University Medical Center. Department of Epidemiology) ; Zhu, Xiaofeng (Case Western Reserve University. Department of Population and Quantitative Health Sciences) ; Asselbergs, Folkert W (University Medical Center Utrecht) ; Kraaijeveld, Adriaan O. (University Medical Center Utrecht) ; Beulens, Joline W. J. (University Medical Center Utrecht) ; Shu, Xiao-Ou (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; Rallidis, Loukianos S. (Kapodistrian University of Athens) ; Pedersen, Oluf (University of Copenhagen) ; Hansen, Torben (University of Copenhagen) ; Mitchell, Paul (University of Sydney) ; Hewitt, Alex W. (University of Melbourne) ; Kähönen, Mika (Tampere University) ; Pérusse, Louis (Institute of Nutrition and Functional Foods (INAF). Université Laval) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Tönjes, Anke (Medical Department III-Endocrinology. Nephrology. Rheumatology. University of Leipzig Medical Center) ; Chen, Yii Der Ida (The Institute for Translational Genomics and Population Sciences. Department of Pediatrics. Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Pennell, Craig E. (School of Medicine and Public Health. College of Health. Medicine and Wellbeing. University of Newcastle) ; Mori, Trevor A (Medical School. Faculty of Health and Medical Sciences. University of Western Australia) ; Lieb, Wolfgang (Institute of Epidemiology. Kiel University) ; Franke, Andre (Christian-Albrechts-University of Kiel. Institute of Clinical Molecular Biology) ; Ohlsson, Claes (Department of Drug Treatment. Sahlgrenska University Hospital) ; Mellström, Dan (Geriatric Medicine. Institute of Medicine. Sahlgrenska Academy. University of Gothenburg) ; Cho, Yoon Shin (Department of Biomedical Science. Hallym University) ; Lee, Hyejin (Department of Internal Medicine. Ewha Womans University School of Medicine) ; Yuan, Jan-Min (Department of Epidemiology. Graduate School of Public Health. University of Pittsburgh) ; Koh, Woon-Puay (Singapore Institute for Clinical Sciences. Agency for Science Technology and Research (A*STAR)) ; Rhee, Sang Youl (Department of Endocrinology and Metabolism. Kyung Hee University School of Medicine) ; Woo, Jeong-Taek (Department of Endocrinology and Metabolism. Kyung Hee University School of Medicine) ; Heid, Iris M. (Department of Genetic Epidemiology. University of Regensburg) ; Stark, Klaus J. (Department of Genetic Epidemiology. University of Regensburg) ; Völzke, Henry (Institute for Community Medicine. University Medicine Greifswald) ; Homuth, Georg (Department of Functional Genomics. Interfaculty Institute for Genetics and Functional Genomics. University of Greifswald and University Medicine Greifswald) ; Evans, Michele K. (Laboratory of Epidemiology and Population Science. National Institute on Aging Intramural Research Program. NIH Biomedical Research Center) ; Zonderman, Alan B (Laboratory of Epidemiology and Population Science. National Institute on Aging Intramural Research Program. NIH Biomedical Research Center) ; Polasek, Ozren (Faculty of Medicine. University of Split) ; Pasterkamp, Gerard (University Medical Center Utrecht) ; Hoefer, Imo E. (University Medical Center Utrecht) ; Redline, Susan (Harvard Medical School) ; Pahkala, Katja (University of Turku) ; Oldehinkel, Albertine J (Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE). University of Groningen. University Medical Center Groningen) ; Snieder, Harold (Department of Epidemiology. University Medical Center Groningen. University of Groningen) ; Biino, Ginevra (National Research Council of Italy. Institute of Molecular Genetics) ; Schmidt, Reinhold (Department of Neurology. Clinical Division of Neurogeriatrics. Medical University of Graz) ; Schmidt, Helena (Medical University Graz) ; Chen, Y. Eugene (Department of Internal Medicine. Division of Cardiology. University of Michigan) ; Bandinelli, Stefania (Local Health Unit Toscana Centro) ; Dedoussis, George (Harokopio University of Athens) ; Thanaraj, Thangavel Alphonse (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Kardia, Sharon L. R. (Department of Epidemiology. School of Public Health. University of Michigan) ; Kato, Norihiro (National Center for Global Health and Medicine) ; Schulze, Matthias B. (Institute of Nutritional Science. University of Potsdam) ; Girotto, Giorgia (Institute for Maternal and Child Health IRCCS "Burlo Garofolo") ; Jung, Bettina (Department of Nephrology. University Hospital Regensburg) ; Böger, Carsten A. (KfH Kidney Center Traunstein) ; Joshi, Peter K. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Bennett, David A. (Department of Neurological Sciences. Rush University Medical Center) ; De Jager, Philip L. (Program in Medical and Population Genetics. Broad Institute) ; Lu, Xiangfeng (Chinese Academy of Medical Sciences) ; Mamakou, Vasiliki (Dromokaiteio Psychiatric Hospital) ; Brown, Morris (Clinical Pharmacology. William Harvey Research Institute. Queen Mary University of London) ; Caulfield, Mark (Queen Mary University of London. William Harvey Research Institute) ; Munroe, Patricia B. (Queen Mary University of London. Barts and The London School of Medicine and Dentistry) ; Guo, Xiuqing (The Institute for Translational Genomics and Population Sciences. Department of Pediatrics. Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Ciullo, Marina (IRCCS Neuromed. Pozzilli) ; Jonas, Jost B. (Institute of Molecular and Clinical Ophthalmology Basel) ; Samani, Nilesh J. (NIHR Leicester Biomedical Research Centre. Glenfield Hospital) ; Kaprio, Jaakko (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Pajukanta, Päivi (University of California. David Geffen School of Medicine at UCLA.) ; Adair, Linda S (Carolina Population Center. University of North Carolina) ; Bechayda, Sonny Augustin (Department of Anthropology. Sociology. and History. University of San Carlos) ; de Silva, H. Janaka (Department of Medicine. Faculty of Medicine. University of Kelaniya) ; Wickremasinghe, Ananda R. (Department of Public Health. Faculty of Medicine. University of Kelaniya) ; Krauss, Ronald M. (Departments of Pediatrics and Medicine. University of California. San Francisco) ; Wu, Jer-Yuarn (Institute of Biomedical Sciences. Academia Sinica) ; Zheng, Wei (Vanderbilt Epidemiology Center. Division of Epidemiology. Vanderbilt University Medical Center) ; den Hollander, Anneke I. (Departments of Ophthalmology and Human Genetics. Radboud University Nijmegen Medical Center) ; Bharadwaj, Dwaipayan (Systems Genomics Laboratory. School of Biotechnology. Jawaharlal Nehru University) ; Correa, Adolfo (University of Mississippi Medical Center) ; Wilson, James G. (University of Mississippi Medical Center) ; Lind, Lars (Uppsala University. Department of Medical Sciences) ; Heng, Chew-Kiat (Khoo Teck Puat-National University Children's Medical Institute. National University Health System) ; Nelson, Amanda E. (Department of Medicine. University of North Carolina) ; Golightly, Yvonne M. (Division of Physical Therapy. University of North Carolina) ; Wilson, James F. (Centre for Global Health Research. Usher Institute. University of Edinburgh) ; Penninx, Brenda WJH (Amsterdam Public Health Research Institute. VU Medical Center Amsterdam) ; Kim, Hyung-Lae (Department of Biochemistry. College of Medicine. Ewha Womans University) ; Attia, John (University of Newcastle. Faculty of Health and Medicine) ; Scott, Rodney J. (University of Newcastle. Faculty of Health and Medicine) ; Rao, D. C. (Washington University School of Medicine) ; Arnett, Donna K. (University of Kentucky. College of Public Health) ; Walker, Mark (Institute of Cellular Medicine (Diabetes). The Medical School. Newcastle University) ; Koistinen, Heikki A. (Minerva Foundation Institute for Medical Research) ; Chandak, Giriraj Ratan (Academy of Scientific and Innovative Research (AcSIR)) ; Yajnik, Chittaranjan S. (Diabetology Research Centre. KEM Hospital and Research Centre) ; Mercader, Josep M. (Diabetes Unit and Center for Genomic Medicine. Massachusetts General Hospital) ; Tusié-Luna, Teresa (Unidad de Biología Molecular y Medicina Genómica. Instituto de Investigaciones Bimédicas UNAM/ Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ; Aguilar-Salinas, Carlos Alberto (Dirección de Nutrición and Unidad de Estudios de Enfermedades Metabólicas. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ; Gonzalez Villalpando, Clicerio (Instituto Nacional de Salud Publica y Centro de Estudios en Diabetes) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Fornage, Myriam (University of Texas Health Science at Houston) ; Tai, E. Shyong (Yong Loo Lin School of Medicine. National University of Singapore and National University Health System) ; van Dam, Rob M. (Yong Loo Lin School of Medicine. National University of Singapore and National University Health System) ; Lehtimäki, Terho (Department of Clinical Chemistry. Finnish Cardiovascular Research Center-Tampere. Faculty of Medicine and Health Technology. Tampere University) ; Chaturvedi, Nish (MRC Unit for Lifelong Health and Ageing at UCL) ; Yokota, Mitsuhiro (Kurume University School of Medicine) ; Liu, Jianjun (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Reilly, Dermot F. (Genetics. Merck Sharp & Dohme) ; McKnight, Amy Jayne (Centre for Public Health. Queen's University of Belfast) ; Kee, Frank (Queen's University Belfast) ; Jöckel, Karl-Heinz (University of Duisburg-Essen) ; McCarthy, Mark I. (University of Oxford) ; Palmer, Colin N. A. (University of Dundee. Ninwells Hospital and Medical School) ; Vitart, Veronique (University of Edinburgh. Western General Hospital) ; Hayward, Caroline (University of Edinburgh. Western General Hospital) ; Simonsick, Eleanor (Intramural Research Program. National Institute on Aging) ; van Duijn, Cornelia M. (Nuffield Department of Population Health. University of Oxford) ; Lu, Fan (The Eye Hospital. School of Ophthalmology and Optometry. Wenzhou Medical University) ; Qu, Jia (The Eye Hospital. School of Ophthalmology and Optometry. Wenzhou Medical University) ; Hishigaki, Haretsugu (Biomedical Technology Research Center. Tokushima Research Institute. Otsuka Pharmaceutical) ; Lin, Xu (Shanghai Chinese Academy of Sciences) ; März, Winfried (Medical University of Graz) ; Parra, Esteban J. (Department of Anthropology. University of Toronto at Mississauga) ; Cruz, Miguel (Instituto Mexicano del Seguro Social) ; Gudnason, Vilmundur (Faculty of Medicine. University of Iceland) ; Tardif, Jean-Claude (Department of Medicine. Faculty of Medecine. Université de Montréal) ; Lettre, Guillaume (Department of Medicine. Faculty of Medicine. Université de Montréal) ; 't Hart, Leen M. (Department of Biomedical Data Sciences. Section Molecular Epidemiology. Leiden University Medical Center) ; Elders, Petra J. M. (Amsterdam UMC. Department of General Practice and Elderly Care. Amsterdam Public Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Kumari, Meena (Institute of Social and Economic Research. University of Essex) ; Kivimaki, Mika (Department of Epidemiology and Public Health. University College London) ; van der Harst, Pim (Department of Cardiology. University Medical Center Groningen. University of Groningen) ; Spector, Tim (Department of Twin Research and Genetic Epidemiology. King's College London) ; Loos, Ruth J. F. (The Mindich Child Health and Development Institute. Icahn School of Medicine at Mount Sinai) ; Province, Michael A. (Division of Statistical Genomics. Department of Genetics. Washington University School of Medicine) ; Psaty, Bruce M. (Kaiser Permanent Washington Health Research Institute) ; Brandslund, Ivan (Institute of Regional Health Research. University of Southern Denmark) ; Pramstaller, Peter P. (Institute for Biomedicine. Eurac Research. Affiliated Institute of the University of Lübeck) ; Christensen, Kaare (Danish Aging Research Center. University of Southern Denmark) ; Ripatti, Samuli (Broad Institute of MIT and Harvard) ; Widén, Elisabeth (Institute for Molecular Medicine Finland (FIMM). HiLIFE. University of Helsinki) ; Hakonarson, Hakon (Department of Pediatrics. Perelman School of Medicine. The University of Pennsylvania) ; Grant, Struan F. A. (Children's Hospital of Philadelphia (Pennsilvània)) ; Kiemeney, Lambertus A. L. M. (Radboud University Medical Center. Radboud Institute for Health Sciences) ; de Graaf, Jacqueline (Radboud University Medical Center. Radboud Institute for Health Sciences) ; Loeffler, Markus (LIFE Research Centre for Civilization Diseases. University of Leipzig) ; Kronenberg, Florian (Institute of Genetic Epidemiology. Department of Genetics and Pharmacology. Medical University of Innsbruck) ; Gu, Dongfeng (School of Medicine. Southern University of Science and Technology) ; Erdmann, Jeanette (University of Lübeck. Institute for Cardiogenetics) ; Schunkert, Heribert (Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) e.V.. Partner site Munich Heart Alliance) ; Franks, Paul W. (Lund University Diabetes Centre) ; Linneberg, Allan (University of Copenhagen. Department of Clinical Medicine) ; Jukema, J. Wouter (Netherlands Heart Institute) ; Khera, Amit V. (Department of Medicine. Harvard Medical School) ; Männikkö, Minna (University of Oulu) ; Jarvelin, Marjo-Riitta (University of Oulu. Biocenter of Oulu) ; Kutalik, Zoltan (University Center for Primary Care and Public Health) ; Cucca, Francesco (University of Sassari) ; Mook-Kanamori, Dennis O. (Department of Public Health and Primary Care. Leiden University Medical Center) ; van Dijk, Ko Willems (Department of Human Genetics. Leiden University Medical Center) ; Watkins, Hugh (Division of Cardiovascular Medicine. Radcliffe Department of Medicine. John Radcliffe Hospital. University of Oxford) ; Strachan, David P. (Population Health Research Institute. St George's University of London) ; Grarup, Niels (Novo Nordisk Foundation Center for Basic Metabolic Research. Faculty of Health and Medical Sciences. University of Copenhagen) ; Sever, Peter (National Heart and Lung Institute. Imperial College London) ; Poulter, Neil (Imperial College London) ; Rotter, Jerome I. (The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. The Institute for Translational Genomics and Population Sciences, Department of Pediatrics) ; Dantoft, Thomas M. (Center for Clinical Research and Prevention. Bispebjerg and Frederiksberg Hospital) ; Karpe, Fredrik (NIHR Oxford Biomedical Research Centre. Churchill Hospital) ; Neville, Matt J. (NIHR Oxford Biomedical Research Centre. Churchill Hospital) ; Timpson, Nicholas J. (University of Bristol) ; Cheng, Ching-Yu (Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP). Duke-NUS Medical School) ; Wong, Tien-Yin (Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP). Duke-NUS Medical School) ; Khor, Chiea Chuen (Genome Institute of Singapore. Agency for Science. Technology and Research) ; Sabanayagam, Charumathi (Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP). Duke-NUS Medical School) ; Peters, Annette (DZHK (German Centre for Cardiovascular Research). Munich Heart Alliance Partner Site) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Hattersley, Andrew T. (University of Exeter Medical School. University of Exeter) ; Pedersen, Nancy L. (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Boomsma, Dorret I. (Amsterdam Reproduction and Development Research Institute. VU Medical Center Amsterdam) ; de Geus, Eco J. C. (Amsterdam Public Health Research Institute. VU Medical Center Amsterdam) ; Cupples, L. Adrienne (Framingham Heart Study. National Heart. Lung. and Blood Institute. US National Institutes of Health) ; van Meurs, Joyce B. J. (Department of Epidemiology. Erasmus MC. University Medical Center Rotterdam) ; Ghanbari, Mohsen (Department of Genetics. School of Medicine. Mashhad University of Medical Sciences) ; Gordon-Larsen, Penny (Carolina Population Center. University of North Carolina) ; Huang, Wei (Department of Genetics. Shanghai-MOST Key Laboratory of Health and Disease Genomics. Chinese National Human Genome Center at Shanghai) ; Kim, Young Jin (Department of Precision Medicine. Division of Genome Science. National Institute of Health) ; Tabara, Yasuharu (Center for Genomic Medicine. Kyoto University Graduate School of Medicine) ; Wareham, Nicholas J. (University of Cambridge (Regne Unit). School of Clinical Medicine) ; Langenberg, Claudia (University of Cambridge (Regne Unit). School of Clinical Medicine) ; Zeggini, Eleftheria (TUM School of Medicine. Technical University of Munich (TUM) and Klinikum Rechts der Isar) ; Kuusisto, Johanna (Institute of Clinical Medicine. Internal Medicine. University of Eastern Finland and Kuopio University Hospital) ; Laakso, Markku (Institute of Clinical Medicine. Internal Medicine. University of Eastern Finland and Kuopio University Hospital) ; Ingelsson, Erik (Stanford Diabetes Research Center. Stanford University) ; Abecasis, Goncalo (Regeneron Pharmaceuticals) ; Chambers, John C. (Imperial College Healthcare NHS Trust. Imperial College London) ; Kooner, Jaspal S. (National Heart and Lung Institute. Imperial College London) ; de Vries, Paul S. (Human Genetics Center. Department of Epidemiology. Human Genetics. and Environmental Sciences. School of Public Health. The University of Texas Health Science Center at Houston) ; Morrison, Alanna (Human Genetics Center. Department of Epidemiology. Human Genetics. and Environmental Sciences. School of Public Health. The University of Texas Health Science Center at Houston) ; North, Kari E. (Department of Epidemiology. University of North Carolina) ; Daviglus, Martha (Institute for Minority Health Research. University of Illinois College of Medicine) ; Kraft, Peter (Department of Biostatistics. Harvard T. H. Chan School of Public Health) ; Martin, Nicholas G (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Whitfield, John B (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Abbas, Shahid (Faisalabad Institute of Cardiology) ; Saleheen, Danish (Department of Cardiology. Columbia University Irving Medical Center) ; Walters, Robin G. (Big Data Institute. University of Oxford) ; Holmes, Michael V (National Institute for Health Research Oxford Biomedical Research Centre. Oxford University Hospitals) ; Black, Corri (Aberdeen Centre for Health Data Science (Aberdeen, Regne Unit)) ; Smith, Blair H (Division of Population Health and Genomics. Ninewells Hospital and Medical School. University of Dundee) ; Justice, Anne E. (Biomedical and Translational Informatics. Geisinger Health) ; Baras, Aris (Regeneron Pharmaceuticals) ; Buring, Julie E. (Harvard Medical School) ; Ridker, Paul M. (Harvard Medical School) ; Chasman, Daniel I. (Harvard Medical School) ; Kooperberg, Charles (Fred Hutchinson Cancer Research Center. Division of Public Health Sciences) ; Wei, Wei-Qi (Department of Biomedical Informatics. Vanderbilt University Medical Center) ; Jarvik, Gail P. (Departments of Medicine (Medical Genetics) and Genome Sciences. University of Washington Medical Center) ; Namjou, Bahram (Center for Autoimmune Genomics and Etiology. Cincinnati Children's Hospital Medical Center (CCHMC)) ; Hayes, M. Geoffrey (Center for Genetic Medicine. Northwestern University. Feinberg School of Medicine) ; Ritchie, Marylyn D. (Department of Genetics. Institute for Biomedical Informatics. Perelman School of Medicine. University of Pennsylvania) ; Jousilahti, Pekka (Department of Public Health and Welfare. Finnish Institute for Health and Welfare) ; Salomaa, Veikko (Department of Public Health and Welfare. Finnish Institute for Health and Welfare) ; Hveem, Kristian (Department of Medicine. Levanger Hospital. Nord-Trøndelag Hospital Trust) ; Åsvold, Bjørn Olav (Department of Endocrinology. St Olavs Hospital. Trondheim University Hospital) ; Kubo, Michiaki (RIKEN Center for Integrative Medical Sciences) ; Kamatani, Yoichiro (The University of Tokyo. Department of Computational Biology and Medical Sciences) ; Okada, Yukinori (Integrated Frontier Research for Medical Science Division. Institute for Open and Transdisciplinary Research Initiatives. Osaka University) ; Murakami, Yoshinori (The University of Tokyo. Institute of Medical Science) ; Thorsteinsdottir, Unnur (Faculty of Medicine. University of Iceland) ; Stefansson, Kari (Faculty of Medicine. University of Iceland) ; Ho, Yuk-Lam (VA Boston Healthcare System) ; Lynch, Julie A. (University of Massachusetts) ; Rader, Daniel J. (Department of Medicine. Perelman School of Medicine. University of Pennsylvania) ; Tsao, Philip S. (Cardiovascular Institute. Stanford University School of Medicine)
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use. Despite advances in prevention and treatment, in particular through reducing low-density lipoprotein cholesterol levels, heart disease remains the leading cause of death worldwide. [...]
2021 - 10.1038/s41586-021-04064-3
Nature, Vol. 600 Núm. 7890 (12 2021) , p. 675-679  
6.
19 p, 19.5 MB 3D reconstruction of syn-tectonic strata deposited during the inversion of salt-related structures : insights from the Llert syncline (South-central Pyrenees) / Ramos Ordoño, Adrià (Universitat de Barcelona. Departament de Dinàmica de la Terra i de l'Oceà) ; Lopez-Mir, Berta (Universitat de Barcelona. Departament de Dinàmica de la Terra i de l'Oceà) ; Wilson, Elisabeth P. (Universitat de Barcelona. Departament de Dinàmica de la Terra i de l'Oceà) ; Martínez Granado, Pablo (Universitat de Barcelona. Departament de Dinàmica de la Terra i de l'Oceà) ; Muñoz de la Fuente, Josep Anton (Universitat de Barcelona. Departament de Dinàmica de la Terra i de l'Oceà)
The Llert syncline is located in the South-central Pyrenees, between the eastern termination of the EW-trending Cotiella Basin and the north-western limb of the NS-trending Turbón-Serrado fold system. [...]
2020 - 10.1344/GeologicaActa2020.18.20
Geologica acta, Vol. 18 (2020) , p. 1-19 (Articles)  
7.
10 p, 2.9 MB Chronicle on 2018 Africa Animal Welfare Conference and Africa Animal Law Convention / Wilson, Amy P. (Animal Law Reform South Africa)
La 2ª Conferencia africana de Bienestar Animal se celebró del 3 al 5 de septiembre de 2018 en el Complejo de las Naciones Unidas para el Medio Ambiente en Nairobi, Kenia. El evento, que es anual, está organizado por la Africa Network for Animal Welfare (ANAW) y está dirigido conjuntamente por las Naciones Unidas para el Medio Ambiente y el Gobierno de Kenia. [...]
The 2nd Africa Animal Welfare Conference was held on 3rd to 5th September 2018 at the United Nations Environment Complex in Nairobi, Kenya. The event, which is an annual one, is organized by the Africa Network for Animal Welfare (ANAW) and is co-hosted by the United Nations Environment and the Government of Kenya. [...]

2019 - 10.5565/rev/da.400
dA Derecho Animal : Forum of Animal Law Studies, Vol. 10 Núm. 1 (2019) , p. 230-239 (Varia)  
8.
24 p, 468.3 KB Animal Law in South Africa : "Until the lions have their own lawyers, the law will continue to protect the hunter" / Wilson, Amy P. (Director and Co-founder Animal Law Reform South Africa, Johannesburg, SA)
Despite the importance of animals to South Africa, animal law is not yet recognized a separate distinct area of law. In an attempt to rectify this, the article provides a high level introduction to this highly complex field. [...]
A pesar de la importancia de los animales para Sudáfrica, el derecho animal aún no es reconocido como un área distinta dentro del Derecho. En un intento por rectificar esto, el artículo proporciona una introducción de alto nivel a este campo tan complejo. [...]

2019 - 10.5565/rev/da.399
dA Derecho Animal : Forum of Animal Law Studies, Vol. 10 Núm. 1 (2019) , p. 35-58 (Artículos)  
9.
36 p, 1.6 MB A global method for calculating plant CSR ecological strategies applied across biomes world-wide / Pierce, Simon (Università degli Studi di Milano. Dipartimento di Scienze Agrarie e Ambientali) ; Negreiros, Daniel (Universidade Federal de Minas Gerais) ; Cerabolini, Bruno Enrico Leone (Università degli Studi dell'Insubria. Dipartimento di Scienze Teoriche e Applicate) ; Kattge, Jens (Max Planck Institute for Biogeochemistry) ; Díaz, Sandra (Universidad Nacional de Córdoba e IMBIV-CONICET (Instituto Multidisciplinario de Investigaciones Científicas y Técnicas)) ; Kleyer, Michael (Oldenburg Universität. Fachbereich Biologie, Erd- und Umweltwissenschaften) ; Shipley, Bill (Université de Sherbrooke. Département de Biologie) ; Wright, Stuart Joseph (Smithsonian Tropical Research Institute (Panamà)) ; Soudzilovskaia, Nadejda A. (Universiteit Leiden. Centrum voor Milieuwetenschappen) ; Onipchenko, Vladimir (Moskovskiĭ gosudarstvennyĭ universitet im. M. V. Lomonosova) ; Van Bodegom, Peter (Rijksuniversiteit te Leiden. Centrum voor Milieuwetenschappen) ; Frenette-Dussault, Cedric (Université de Sherbrooke. Département de Biologie) ; Weiher, Evan (University of Wisconsin. Department of Biology) ; Pinho, Bruno X. (Universidade Federal de Pernambuco. Departamento de Botânica) ; Cornelissen, J. H. C. (Vrije Universiteit Amsterdam. Department of Ecological Science) ; Grime, John Philip (University of Sheffield. Department of Animal and Plant Sciences) ; Thompson, Ken (University of Sheffield. Department of Animal and Plant Sciences) ; Hunt, Roderick (University of Exeter (Gran Bretanya). College of Life and Environmental Sciences) ; Wilson, Peter J. (University of Sheffield. Department of Animal and Plant Sciences) ; Buffa, Gabriella (Università Ca'Foscari Venezia. Dipartimento di Scienze Ambientali, Informatica e Statistica) ; Nyakunga, Oliver C. (Università Ca'Foscari Venezia. Dipartimento di Scienze Ambientali, Informatica e Statistica) ; Reich, Peter (University of Minnesota. Department of Forest Resources) ; Caccianiga, Marco (Università degli Studi di Milano. Dipartimento di Bioscienze) ; Mangili, Federico (Università degli Studi di Milano. Dipartimento di Bioscienze) ; Ceriani, Roberta M. (Centro Flora Autoctona) ; Luzzaro, Alessandra (Università degli Studi di Milano. Dipartimento di Scienze Agrarie e Ambientali) ; Brusa, Guido (Università degli Studi dell'Insubria. Dipartimento di Scienze Teoriche e Applicate) ; Siefert, Andrew (University of California, Department of Evolution and Ecology) ; Barbosa, Newton P. U. (Universidade Federal de Minas Gerais) ; III, Francis Stuart Chapin (University of Alaska Fairbanks. Department of Biology and Wildlife) ; Cornwell, William (University of New South Wales. School of Biological, Earth and Environmental Sciences) ; Jingyun, Fang (Zhongguo ke xue yuan. Institute of Botany) ; Fernandes, Geraldo Wilson (Universidade Federal de Minas Gerais) ; Garnier, Eric (Centre national de la recherche scientifique (França). Centre d'Écologie Fonctionnelle et Évolutive) ; Le Stradic, Soizig (Université de Liège (Bèlgica). Gembloux Agro-Bio Tech) ; Melo, Felipe P. L. (Universidade Federal de Pernambuco. Departamento de Botânica) ; Slaviero, Antonio (Università Ca'Foscari Venezia. Dipartimento di Scienze Ambientali, Informatica e Statistica) ; Tabarelli, Marcelo (Universidade Federal de Pernambuco. Departamento de Botânica) ; Tampucci, Duccio (Università degli Studi di Milano. Dipartimento di Bioscienze) ; Peñuelas, Josep (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
1. Competitor, stress-tolerator, ruderal (CSR) theory is a prominent plant functional strategy scheme previously applied to local floras. Globally, the wide geographic and phylogenetic coverage of available values of leaf area (LA), leaf dry matter content (LDMC) and specific leaf area (SLA) (representing, respectively, interspecific variation in plant size and conservative vs. [...]
2017 - 10.1111/1365-2435.12722
Functional ecology, Vol. 31, issue 2 (Feb. 2017) , p. 444-457  
10.
27 p, 2.2 MB Interlaboratory comparison study of calibration standards for foraminiferal Mg/Ca thermometry / Greaves, Mervyn (University of Cambridge. Department of Earth Sciences) ; Caillon, Nicolas (Centre National de la Recherche Scientifique (França)) ; Rebaubier, Helene (Centre National de la Recherche Scientifique (França)) ; Bartoli, G. (Kiel University. Institute für Geowissenschaften) ; Bohaty, Steven (University of Southampton. School of Ocean and Earth Science) ; Cacho, Isabel (Universitat de Barcelona. Departament d'Estratigrafia, Paleontologia i Geociències Marines) ; Clarke, L. (Bangor University. School of Ocean Sciences) ; Cooper, M. (National Oceanography Centre) ; Daunt, C. (University of Cambridge. Department of Earth Sciences) ; Delaney, M. (University of California. Department of Ocean Sciences) ; de Menocal, P. (Columbia University. Lamont-Doherty Earth Observatory) ; Dutton, Andrea (Australian National University. Research School of Earth Sciences) ; Eggins, Stephen (Australian National University. Research School of Earth Sciences) ; Elderfield, Henry (University of Cambridge. Department of Earth Sciences) ; Garbe-Schoenberg, Dieter (Kiel University. Institute für Geowissenschaften) ; Goddard, Ethan (University of South Florida. College of Marine Science) ; Green, D. (National Oceanography Centre) ; Groeneveld, J. (University of Bremen. Research Center Ocean Margins) ; Hastings, D. (Eckerd College. Collegium of Natural Sciences) ; Hathorne, E. (University of Bremen. Research Center Ocean Margins) ; Kimoto, K. (Institute of Observational Research for Global Change) ; Klinkhammer, Gary (Oregon State University. College of Oceanography) ; Labeyrie, L. (Centre National de la Recherche Scientifique (França)) ; Lea, David W. (University of California. Department of Geological Sciences) ; Marchitto, Thomas (University of Colorado. INSTAAR) ; Martínez Botí, M. A. (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ; Mortyn, P. Graham (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ; Ni, Y. (Research Institute of Petroleum Exploration and Development) ; Nuernberg, D. (IFM-GEOMAR (Kiel, Alemanya)) ; Paradis, G. (University of California. Department of Geological Sciences) ; Pena, L. (Universitat de Barcelona. Departament d'Estratigrafia, Paleontologia i Geociències Marines) ; Quinn, T. (University of South Florida. College of Marine Science) ; Rosenthal, Y. (State University of New Jersey. Department of Geology) ; Russell, A. (University of California. Department of Geology) ; Sagawa, T. (Kochi University. Center for Advanced Marine Core Research) ; Sosdian, S. (State University of New Jersey. Department of Geology) ; Stott, Lowell D (University of South California. Department of Earth Sciences) ; Tachikawa, K. (Centre National de la Recherche Scientifique (França)) ; Tappa, E. (University of South Carolina. Department of Geological Sciences) ; Thunell, Robert C. (University of South Carolina. Department of Geological Sciences) ; Wilson, P. A. (National Oceanography Centre)
An interlaboratory study of Mg/Ca and Sr/Ca ratios in three commercially available carbonate reference materials (BAM RS3, CMSI 1767, and ECRM 752-1) was performed with the participation of 25 laboratories that determine foraminiferal Mg/Ca ratios worldwide. [...]
2008 - 10.1029/2008GC001974
Geochemistry, geophysics, geosystems, Vol. 9, issue 8 (Aug. 2008) , p. 1-27  

Articles : 18 registres trobats   1 - 10següent  anar al registre:
Vegeu també: autors amb noms similars
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