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15 p, 3.0 MB Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia / Zielen, Stefan (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Duecker, Ruth Pia (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Woelke, Sandra (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Donath, Helena (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Bakhtiar, Shahrzad (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Buecker, Aileen (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Kreyenberg, Hermann (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Huenecke, Sabine (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Bader, Peter (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ; Mahlaoui, Nizar (Necker Children's University Hospital. Pediatric Immunology-Hematology and Rheumatology Unit) ; Ehl, Stephan (University of Freiburg. Institute for Immunodeficiency) ; El-Helou, Sabine M. (Hannover Medical School. Department of Rheumatology and Immunology) ; Pietrucha, Barbara (The Children's Memorial Health Institute. Department of Immunology) ; Plebani, Alessandro (University of Brescia. Department of Clinical and Experimental Sciences) ; van der Flier, Michiel (Radboud University Medical Center. Section Pediatric Infectious Diseases) ; van Aerde, Koen (Radboud University Medical Center. Department of Pediatrics) ; Kilic, Sara S. (Uludag University. Department of Pediatric Immunology and Rheumatology) ; Reda, Shereen M. (Ain Shams University. Department of Pediatrics) ; Kostyuchenko, Larysa (Western Ukrainian Specialized Children's Medical Centre) ; McDermott, Elizabeth (Nottingham University Hospitals NHS Trust (Regne Unit)) ; Galal, Nermeen (Cairo University Specialized Pediatric Hospital. Department of Pediatrics) ; Pignata, Claudio (Federico II University. Department of Translational Medical Sciences) ; Santos-Pérez, Juan Luis (Hospital Universitario Virgen de las Nieves (Granada)) ; Laws, Hans-Juergen (Heinrich-Heine University. Department of Pediatric Oncology, Hematology and Clinical Immunology) ; Niehues, Tim (Centre for Child and Adolescent Health (Krefeld, Germany)) ; Kutukculer, Necil (Ege University. Department of Pediatric Immunology) ; Seidel, Markus G. (Medical University Graz. Department of Pediatrics and Adolescent Medicine) ; Marques, Laura (Porto Hospital Center. Pediatric Department) ; Ciznar, Peter (Comenius University in Bratislava. Pediatric Department) ; Edgar, John David M. (The Royal Hospitals & Queen's University) ; Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; von Bernuth, Horst (Charité - Universitätsmedizin Berlin) ; Krueger, Renate (Charité - Universitätsmedizin Berlin) ; Meyts, Isabelle (University Hospitals Leuven (Bèlgica)) ; Baumann, Ulrich (Hannover Medical School. Department of Paediatric Pulmonology, Allergy and Neonatology) ; Kanariou, Maria ("Aghia Sophia" Children's Hospital. Department of Immunology and Histocompatibility) ; Grimbacher, Bodo (Albert-Ludwigs University) ; Hauck, Fabian (Ludwig-Maximilians-University Munich. Department of Pediatrics) ; Graf, Dagmar (MVZ Dr. Reising-Ackermann Und Kollegen (Leipzig, Germany)) ; Granado, Luis Ignacio Gonzalez (Universidad Complutense de Madrid) ; Prader, Seraina (University Children's Hospital Zurich. Division of Immunology and Children's Research Center) ; Reisli, Ismail (Necmettin Erbakan University. Department of Pediatrics) ; Slatter, Mary (Newcastle University. Primary Immunodeficiency Group, Paediatric Immunology and Haematopoietic Stem Cell Transplantation) ; Rodríguez-Gallego, Carlos (University Fernando Pessoa Canarias. Department of Immunology) ; Arkwright, Peter D. (University of Manchester. Lydia Becker Institute of Immunology and Inflammation) ; Bethune, Claire (University Hospitals Plymouth NHS Trust (Regne Unit)) ; Deripapa, Elena (National Medical Research Center of Pediatric Hematology, Oncology and Immunology (Moscow, Russia)) ; Sharapova, Svetlana O. (Belarusian Research Center for Pediatric Oncology, Hematology and Immunology. Research Department) ; Lehmberg, Kai (University Medical Center Hamburg-Eppendorf. Division for Pediatric Stem Cell Transplantation and Immunology) ; Davies, E. Graham (Great Ormond Street Hospital for Children (Londres)) ; Schuetz, Catharina (Technische Universität Dresden. Department of Pediatrics) ; Kindle, Gerhard (University of Freiburg. FREEZE Biobank) ; Schubert, Ralf (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ; Universitat Autònoma de Barcelona
Patients with ataxia-telangiectasia (A-T) sufer from progressive cerebellar ataxia, immunodefciency, respiratory failure, and cancer susceptibility. From a clinical point of view, A-T patients with IgA defciency show more symptoms and may have a poorer prognosis. [...]
2021 - 10.1007/s10875-021-01090-8
Journal of Clinical Immunology, Vol. 41 (september 2021) , p. 1878-1892  

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