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Artículos, Encontrados 4 registros
Artículos Encontrados 4 registros  
1.
9 p, 990.5 KB International stroke genetics consortium recommendations for studies of genetics of stroke outcome and recovery / Lindgren, Arne G (Skåne University Hospital (Suècia)) ; Braun, Robynne G (Department of Neurology, University of Maryland) ; Juhl Majersik, Jennifer (Department of Neurology, University of Utah) ; Clatworthy, Philip (North Bristol NHS Trust) ; Mainali, Shraddha (The Ohio State University) ; Derdeyn, Colin P (University of Iowa) ; Maguire, Jane (University of Technology Sydney) ; Jern, Christina (Sahlgrenska University Hospital) ; Rosand, Jonathan (Massachusetts General Hospital) ; Cole, John W. (University of Maryland School of Medicine) ; Lee, Jin-Moo (Washington University School of Medicine, St. Louis) ; Khatri, Pooja (University of Cincinnati) ; Nyquist, Paul (Johns Hopkins School of Medicine, Baltimore) ; Debette, Stéphanie (Bordeaux University Hospital(França)) ; Keat Wei, Loo (Universiti Tunku Abdul Rahman, Perak) ; Rundek, Tatjana (Department of Neurology, , Miami) ; Leifer, Dana (Weill Cornell Medicine, New York) ; Thijs, Vincent (Florey Institute of Neuroscience and Mental Health, Melbourne) ; Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ; Heitsch, Laura (Washington University School of Medicine) ; Prasad, Kameshwar (Rajendra Institute of Medical Sciences) ; Jimenez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ; Dichgans, Martin (Institute for Stroke and Dementia Research (Munic, Alemanya)) ; Rost, Natalia S (Massachusetts General Hospital) ; Cramer, Steven C (California Rehabilitation Institute) ; Bernhardt, Julie (Florey Institute of Neuroscience and Mental Health (Melbourne, Austràlia)) ; Worrall, Bradford B (University of Virginia) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Numerous biological mechanisms contribute to outcome after stroke, including brain injury, inflammation, and repair mechanisms. Clinical genetic studies have the potential to discover biological mechanisms affecting stroke recovery in humans and identify intervention targets. [...]
2021 - 10.1177/17474930211007288
International Journal of Stroke, Vol. 17 (april 2021) , p. 260-268  
2.
13 p, 2.7 MB White matter hyperintensity quantification in large-scale clinical acute ischemic stroke cohorts - The MRI-GENIE study / Schirmer, Markus D. (Massachusetts General Hospital) ; Dalca, Adrian V. (Massachusetts Institute of Technology) ; Sridharan, Ramesh (Massachusetts Institute of Technology) ; Giese, Anne-Katrin (Massachusetts General Hospital) ; Donahue, Kathleen L. (Massachusetts General Hospital) ; Nardin, Marco J. (Massachusetts General Hospital) ; Mocking, Steven J.T. (Massachusetts General Hospital) ; McIntosh, Elissa C. (Massachusetts General Hospital) ; Frid, Petrea (Lund University) ; Wasselius, Johan (Lund University) ; Cole, John W. (University of Maryland School of Medicine) ; Holmegaard, Lukas (University of Gothenburg) ; Jern, Christina (University of Gothenburg) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lemmens, Robin (Leuven Research Institute for Neuroscience and Disease) ; Lindgren, Arne G. (Lund University) ; Meschia, James F. (Mayo Clinic, Florida) ; Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rundek, Tatjana (Miller School of Medicine) ; Sacco, Ralph L. (Miller School of Medicine) ; Schmidt, Reinhold (Medical University Graz) ; Sharma, Pankaj (Royal Holloway University of London) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Thijs, Vincent (Florey Institute of Neuroscience and Mental Health) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Vagal, Achala (University of Cincinnati College of Medicine) ; Xu, Huichun (University of Maryland School of Medicine) ; Kittner, Steven J. (University of Maryland School of Medicine) ; McArdle, Patrick F. (University of Maryland School of Medicine) ; Mitchell, Braxton D. (University of Maryland School of Medicine) ; Rosand, Jonathan (Massachusetts General Hospital) ; Worrall, Bradford B. (University of Virginia) ; Wu, Ona (Massachusetts General Hospital) ; Golland, Polina (Massachusetts Institute of Technology) ; Rost, Natalia S. (Massachusetts General Hospital) ; Universitat Autònoma de Barcelona
White matter hyperintensity (WMH) burden is a critically important cerebrovascular phenotype linked to prediction of diagnosis and prognosis of diseases, such as acute ischemic stroke (AIS). However, current approaches to its quantification on clinical MRI often rely on time intensive manual delineation of the disease on T2 fluid attenuated inverse recovery (FLAIR), which hinders high-throughput analyses such as genetic discovery. [...]
2019 - 10.1016/j.nicl.2019.101884
NeuroImage, Vol. 23 (may 2019)  
3.
15 p, 517.3 KB GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke / Fernandez Cadenas, Israel (Hospital Universitari Vall d'Hebron) ; Mendióroz, Maite (Hospital Universitari Vall d'Hebron) ; Giralt, Dolors (Hospital Universitari Vall d'Hebron) ; Nafría, Cristina (Hospital Universitari Vall d'Hebron) ; Garcia, Elena (Fundació Docència i Recerca Mutua Terrassa) ; Carrera, Caty (Hospital Universitari Vall d'Hebron) ; Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mutua Terrassa) ; Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron) ; Ribó, Marc (Hospital Universitari Vall d'Hebron) ; Castellanos, Mar (Hospital Universitari de Girona Doctor Josep Trueta) ; Martínez, Sergi (Institut d'Investigació Biomèdica Sant Pau) ; Freijo, Mari Mar (Hospital de Basurto (Bilbao, Biscaia)) ; Jiménez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ; Rubiera, Marta (Hospital Universitari Vall d'Hebron) ; Alvarez Sabín, José (Hospital Universitari Vall d'Hebron) ; Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ; Font, Maria Angels (Hospital Universitari de Bellvitge) ; Grau Olivares, Marta (Hospital del Sagrat Cor (Barcelona, Catalunya)) ; Palomeras, Ernest (Hospital de Mataró. Consorci Sanitari del Maresme) ; Perez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martinez Zabaleta, Maite (Hospital Universitario de Donostia.(Sant Sebastià, País Basc)) ; Masjuan, Jaime (Hospital Universitario Ramón y Cajal (Madrid)) ; Moniche, Francisco (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Canovas, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Piñana, Carlos (Hospital Universitario Virgen de las Nieves (Granada)) ; Purroy, Francisco (Hospital Arnau de Vilanova (Lleida, Catalunya)) ; Cocho, Dolores (Hospital General de Granollers) ; Navas, Inma (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ; Tejero, Carlos (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ; Aymerich, Nuria (Complejo Hospitalario de Navarra) ; Cullell, Natalia (Fundació Docència i Recerca Mutua Terrassa) ; Muiño, Elena (Fundació Docència i Recerca Mutua Terrassa) ; Serena, Joaquín (Hospital Universitari de Girona Doctor Josep Trueta) ; Rubio, Francisco (Hospital Universitari de Bellvitge) ; Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roquer González, Jaume (Hospital del Mar (Barcelona, Catalunya)) ; Arenillas, Juan F (Hospital Clínico Universitario (Valladolid)) ; Martí Fábregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Keene, Keith (Center for Health Disparities. East Carolina University) ; Chen, Wei-Min (Department of Public Health Sciences; Center for Public Health Genomics, University of Virginia) ; Worrall, Bradford (Department of Neurology; Department of Public Health Sciences, University of Virginia) ; Sale, Michele (Center for Public Health Genomics, University of Virginia) ; Arboix, Adrià (Hospital del Sagrat Cor (Barcelona, Catalunya)) ; Krupinski, Jerzy (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ; Montaner, Joan (Hospital Universitari Vall d'Hebron) ; GRECOSstudy group ; Universitat Autònoma de Barcelona
Background and Purpose-Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 - 10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153  
4.
11 p, 168.8 KB Genetic variants in CETP increase risk of intracerebral hemorrhage / Anderson, Christopher D. (Broad Institute of MIT and Harvard) ; Falcone, Guido J. (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Phuah, Chia-Ling (Broad Institute of MIT and Harvard) ; Radmanesh, Farid (Broad Institute of MIT and Harvard) ; Brouwers, H. Bart (Broad Institute of MIT and Harvard) ; Battey, Thomas W. K. (Broad Institute of MIT and Harvard) ; Biffi, Alessandro (Division of Psychiatry, Department of Psychiatry, MGH) ; Peloso, Gina M. (Broad Institute of MIT and Harvard) ; Liu, Dajiang J. (Institute of Personalized Medicine, Penn State College of Medicine) ; Ayres, Alison M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Goldstein, Joshua N. (Department of Emergency Medicine, MGH) ; Viswanathan, Anand (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Greenberg, Steven M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Selim, Magdy (Beth Israel Deaconess Medical Center) ; Meschia, James F. (Mayo Clinic) ; Brown, Devin L. (University of Michigan Health System) ; Worrall, Bradford B. (University of Virginia Health System) ; Silliman, Scott L. (University of Florida College of Medicine) ; Tirschwell, David L. (University of Washington) ; Flaherty, Matthew L. (University of Cincinnati College of Medicine) ; Kraft, Peter (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Jagiella, Jeremiasz M. (Jagiellonian University Medical College) ; Schmidt, Helena (Medical University Graz) ; Hansen, Björn M. (Skåne University Hospital (Suècia)) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soriano Tàrraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; van Nieuwenhuizen, Koen M. (University Medical Center Utrecht) ; Klijn, Catharina J. M. (Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center) ; Rannikmae, Kristiina (University of Edinburgh) ; Samarasekera, Neshika (University of Edinburgh) ; Salman, Rustam Al-Shahi (University of Edinburgh) ; Sudlow, Catherine L. (University of Edinburgh) ; Deary, Ian J. (University of Edinburgh) ; Morotti, Andrea (Neurology Clinic, University of Brescia) ; Pezzini, Alessandro (Neurology Clinic, University of Brescia) ; Pera, Joanna (Jagiellonian University Medical College) ; Urbanik, Andrzej (Jagiellonian University Medical College) ; Pichler, Alexander (Medical University of Graz) ; Enzinger, Christian (Medical University of Graz) ; Norrving, Bo (Skåne University Hospital (Suècia)) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernandez Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Delgado Martínez, Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roquer González, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lindgren, Arne (Skåne University Hospital (Suècia)) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Schmidt, Reinhold (Medical University of Graz) ; Kidwell, Chelsea S. (University of Arizona) ; Kittner, Steven J. (Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine) ; Waddy, Salina P. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Langefeld, Carl D. (Wake Forest University) ; Abecasis, Goncalo (University of Michigan School of Public Health) ; Willer, Cristen J. (University of Michigan Medical School) ; Kathiresan, Sekar (Cardiovascular Disease Prevention Center, MGH) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Rosand, Jonathan (Broad Institute of MIT and Harvard) ; Universitat Autònoma de Barcelona. Departament de Neurologia
In observational epidemiologic studies, higher plasma high-density lipoprotein cholesterol (HDL-C) has been associated with increased risk of intracerebral hemorrhage (ICH). DNA sequence variants that decrease cholesteryl ester transfer protein (CETP) gene activity increase plasma HDL-C; as such, medicines that inhibit CETP and raise HDL-C are in clinical development. [...]
2016 - 10.1002/ana.24780
Annals of neurology, Vol. 80 (october 2016) , p. 730-740  

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