Resultados globales: 5 registros encontrados en 0.01 segundos.
Artículos, Encontrados 5 registros
Artículos Encontrados 5 registros  
1.
9 p, 491.4 KB Semantic Verbal Fluency Pattern, Dementia Rating Scores and Adaptive Behavior Correlate With Plasma Aβ Concentrations in Down Syndrome Young Adults / Hoyo Soriano, Laura del (Institut Hospital del Mar d'Investigacions Mèdiques) ; Xicota, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ; Sánchez-Benavides, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuenca-Royo, Aida (Institut Hospital del Mar d'Investigacions Mèdiques) ; de Sola, Susana (Institut Hospital del Mar d'Investigacions Mèdiques) ; Langohr, Klaus (Institut Hospital del Mar d'Investigacions Mèdiques) ; Fagundo, Ana B. (Hospital Universitari de Bellvitge) ; Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Dierssen, Mara (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques)
Down syndrome (DS) is an intellectual disability (ID) disorder in which language and specifically, verbal fluency are strongly impaired domains; nearly all adults show neuropathology of Alzheimer's disease (AD), including amyloid deposition by their fifth decade of life. [...]
2015 - 10.3389/fnbeh.2015.00301
Frontiers in Behavioral Neuroscience, Vol. 9 (november 2015)  
2.
7 p, 1.1 MB Depressive mood ratings are reduced by MDMA in female polydrug ecstasy users homozygous for the l-allele of the serotonin transporter / Kuypers, Kim P. C. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; De La Torre, Rafael (Universitat Pompeu Fabra) ; Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Xicota, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ; de Sousa Fernandes Perna, Elizabeth B. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; Theunissen, E. L. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; Ramaekers, Johannes G. (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
MDMA exerts its main effects via the serotonergic system and the serotonin transporter. The gene coding for this transporter determines the expression rate of the transporter. Previously it was shown that healthy individuals with the short allelic variant ('s-group') of the 5-HTTLPR-polymorphism displayed more anxiety and negative mood, and had a lower transcriptional efficiency compared to individuals who are homozygous for the l-allele ('l-group'). [...]
2018 - 10.1038/s41598-018-19618-1
Scientific reports, Vol. 8 (january 2018)  
3.
26 p, 562.2 KB Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases / Rodríguez-Morató, Jose (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Xicota, Laura (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Fitó, Montserrat (Institut Hospital del Mar d'Investigacions Mèdiques) ; Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Dierssen, Mara (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; De La Torre, Rafael (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut)
Adherence to the Mediterranean Diet (MD) has been associated with a reduced incidence of neurodegenerative diseases and better cognitive performance. Virgin olive oil, the main source of lipids in the MD, is rich in minor phenolic components, particularly hydroxytyrosol (HT). [...]
2015 - 10.3390/molecules20034655
Molecules, Vol. 20 (march 2015) , p. 4655-4680  
4.
10 p, 560.4 KB MDMA-induced indifference to negative sounds is mediated by the 5-HT receptor / Kuypers, Kim P. C (Maastricht University. Department of Neuropsychology and Psychopharmacology) ; De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ; Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pizarro, N. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Xicota, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ramaekers, Johannes G (Maastricht, the Netherlands)
MDMA has been shown to induce feelings of sociability, a positive emotional bias and enhanced empathy. While previous research has used only visual emotional stimuli, communication entails more than that single dimension and it is known that auditory information is also crucial in this process. [...]
2017 - 10.1007/s00213-017-4699-1
Psychopharmacology, Vol. 235 (july 2017) , p. 481-490  
5.
9 p, 894.2 KB VNTR-DAT1 and COMTVal158Met Genotypes Modulate Mental Flexibility and Adaptive Behavior Skills in Down Syndrome / del Hoyo, Laura (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Xicota, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ; Langohr, Klaus (Institut Hospital del Mar d'Investigacions Mèdiques) ; Sánchez-Benavides, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques) ; de Sola, Susana (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuenca-Royo, Aida (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodriguez, Joan (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodríguez-Morató, Jose (Institut Hospital del Mar d'Investigacions Mèdiques) ; Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Dierssen, Mara (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; De La Torre, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques)
Down syndrome (DS) is an aneuploidy syndrome that is caused by trisomy for human chromosome 21 resulting in a characteristic cognitive and behavioral phenotype, which includes executive functioning and adaptive behavior difficulties possibly due to prefrontal cortex (PFC) deficits. [...]
2016 - 10.3389/fnbeh.2016.00193
Frontiers in Behavioral Neuroscience, Vol. 10 (october 2016)  

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