Resultados globales: 5 registros encontrados en 0.02 segundos.
Artículos, Encontrados 5 registros
Artículos Encontrados 5 registros  
1.
12 p, 2.5 MB Distinct roles for PARP-1 and PARP-2 in c-Myc-driven B-cell lymphoma in mice / Galindo Campos, Miguel A. (Cancer Research Program. Hospital del Mar Medical Research Institute (IMIM)) ; Lutfi, Nura (Cancer Research Program. Hospital del Mar Medical Research Institute (IMIM)) ; Bonnin, Sarah (Centre de Regulació Genòmica) ; Martínez Cáceres, Carlos (Instituto Murciano de Investigación Biosanitaria-Laboratorio de Investigación Biosanitaria-Arrixaca) ; Velasco-Hernández, Talia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; García-Hernández, Violeta (Cancer Research Program. Hospital del Mar Medical Research Institute (IMIM)) ; Martín Caballero, Juan (Instituto Cajal. Consejo Superior de Investigaciones Científicas (CSIC)) ; Ampurdanés, Coral (Cancer Research Program. Hospital del Mar Medical Research Institute (IMIM)) ; Gimeno, Ramón (Laboratory of Immunology. Department of Pathology) ; Colomo, Lluís (Hospital del Mar (Barcelona, Catalunya)) ; Roué, Gaël (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Guilbaud, Guillaume (Division of Protein and Nucleic Acid Chemistry. Medical Research Council Laboratory of Molecular Biology) ; Dantzer, Françoise (Biotechnology and Cell Signaling. Unité Mixte de Recherche (UMR) 7242 Centre National de la Recherche Scientifique. Laboratory of Excellence Medalis. École Supérieure de Biotechnologie de Strasbourg. Strasbourg University) ; Navarro, Pilar (Hospital del Mar Medical Research Institute. Unidad Asociada IIBB-CSIC) ; Murga, Matilde (Genomic Instability Group. Spanish National Cancer Research Centre) ; Fernández Capetillo, Oscar (Science for Life Laboratory. Department of Medical Biochemistry and Biophysics. Karolinska Institutet) ; Bigas Salvans, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sale, Julian E. (Division of Protein and Nucleic Acid Chemistry. Medical Research Council Laboratory of Molecular Biology) ; Yélamos, José (Laboratory of Immunology. Department of Pathology)
Dysregulation of the c-Myc oncogene occurs in a wide variety of hematologic malignancies, and its overexpression has been linked with aggressive tumor progression. Here, we show that poly (ADP-ribose) polymerase 1 (PARP-1) and PARP-2 exert opposing influences on progression of c-Myc-driven B-cell lymphoma. [...]
2022 - 10.1182/blood.2021012805
Blood, Vol. 139 Núm. 2 (13 2022) , p. 228-239  
2.
13 p, 23.3 MB Increased PARP Activity and DNA Damage in NSCLC Patients : influence of COPD / Tang, Jun (Institut Hospital del Mar d'Investigacions Mèdiques) ; Curull Serrano, Víctor (Institut Hospital del Mar d'Investigacions Mèdiques) ; Wang, Xuejie (Institut Hospital del Mar d'Investigacions Mèdiques) ; Ampurdanés, Coral (Institut Hospital del Mar d'Investigacions Mèdiques) ; Duran-Jordà, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pijuan, Lara (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rodríguez-Fuster, Alberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Aguiló Espases, Rafael (Institut Hospital del Mar d'Investigacions Mèdiques) ; Yélamos, José (Institut Hospital del Mar d'Investigacions Mèdiques) ; Barreiro, Esther (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
(1) Background: Lung cancer (LC) is a major leading cause of death worldwide. Poly (ADP-ribose) polymerase (PARP)-1 and PARP-2 are key players in cancer. We aimed to assess PARP-1 and PARP-2 expression and activity and DNA damage in tumors and non-tumor lungs from patients with/without chronic obstructive pulmonary disease (COPD). [...]
2020 - 10.3390/cancers12113333
Cancers, Vol. 12 Núm. 11 (2020) , p. 3333  
3.
8 p, 2.1 MB Impact of cytomegalovirus infection on B cell differentiation and cytokine production in multiple sclerosis / Zabalza, Ana (Institut Hospital del Mar d'Investigacions Mèdiques) ; Vera, Andrea (Institut Hospital del Mar d'Investigacions Mèdiques) ; Alari-Pahissa, Elisenda (Universitat Pompeu Fabra) ; Munteis, Elvira (Institut Hospital del Mar d'Investigacions Mèdiques) ; Moreira Villanueva, Antía (Althaia Xarxa Assistencial Universitària de Manresa) ; Yélamos, José (Institut Hospital del Mar d'Investigacions Mèdiques) ; Llop, Mireia (Institut Hospital del Mar d'Investigacions Mèdiques) ; López-Botet, Miguel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Martínez-Rodríguez, Jose E. (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona. Departament de Medicina
Human cytomegalovirus (HCMV) infection has been recently associated with a low risk of multiple sclerosis (MS), yet the basis behind this observation remains uncertain. In this study, we aimed to determine in MS patients whether HCMV induces modifications in the peripheral B cell compartment. [...]
2020 - 10.1186/s12974-020-01840-2
Journal of neuroinflammation, Vol. 17 (may 2020)  
4.
43 p, 3.9 MB LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells / Cebrià Costa, Joan Pau (Vall d'Hebron Institut d'Oncologia) ; Pascual Reguant, Laura (Vall d'Hebron Institut d'Oncologia) ; Gonzalez-Perez, Abel (Institute for Research in Biomedicine (IRB Barcelona)) ; Serra-Bardenys, Gemma (Vall d'Hebron Institut d'Oncologia) ; Querol, Jessica (Vall d'Hebron Institut d'Oncologia) ; Cosín Tomás, Marc (Vall d'Hebron Institut d'Oncologia) ; Verde, Gaetano (Universitat Internacional de Catalunya. Facultat de Ciències de la Salut) ; Aiese Cigliano, Riccardo (Sequentia Biotech SL) ; Sanseverino, Walter. (Sequentia Biotech SL) ; Segura-Bayona, Sandra (Institute for Research in Biomedicine (IRB Barcelona)) ; Iturbide, Ane (Institute of Epigenetics and Stem Cells) ; Andreu Martínez, David (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Nuciforo, Paolo. (Vall d'Hebron Institut d'Oncologia) ; Bernadó Morales, Cristina (Centro de Investigación Biomédica en Red de Cáncer) ; Rodilla, Verónica (Vall d'Hebron Institut d'Oncologia) ; Arribas, Joaquín V (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Yélamos, José (Institut Hospital del Mar d'Investigacions Mèdiques) ; Garcia de Herreros, Antonio (Institut Hospital del Mar d'Investigacions Mèdiques) ; Stracker, Travis H. (Institute for Research in Biomedicine (IRB Barcelona)) ; Peiró, Sandra (Vall d'Hebron Institut d'Oncologia)
Oxidation of H3 at lysine 4 (H3K4ox) by lysyl oxidase-like 2 (LOXL2) generates an H3 modification with an unknown physiological function. We find that LOXL2 and H3K4ox are higher in triple-negative breast cancer (TNBC) cell lines and patient-derived xenografts (PDXs) than those from other breast cancer subtypes. [...]
2020 - 10.1038/s41388-019-0969-1
Oncogene, Vol. 39 (2020) , p. 79-121  
5.
5 p, 116.6 KB Basophil Activation Test identifies the patients with Chronic Spontaneous Urticaria suffering the most active disease / Curto-Barredo, Laia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Yelamos, Jose (Institut Hospital del Mar d'Investigacions Mèdiques) ; Gimeno Martínez, Ramón (Institut Hospital del Mar d'Investigacions Mèdiques) ; Mojal, Sergi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Pujol Vallverdú, Ramón M (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giménez-Arnau, Ana M.. 1961- (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
The basophil activation test showing CD63 up regulation could be a specific and sensitive in vitro complementary text to the in vivo autologous serum skin test for the activity assessment of the patients suffering autoimmune chronic spontaneous urticaria. [...]
2016 - 10.1002/iid3.125
Immunity, Inflammation and Disease, Vol. 4 (october 2016) , p. 441-445  

Vea también: autores con nombres similares
4 Yelamos, J.
4 Yélamos, J.
5 Yélamos, Jose
5 Yélamos, José
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