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14 p, 1.3 MB Detection of hyper-conserved regions in hepatitis B virus X gene potentially useful for gene therapy / González, Carolina (Hospital Universitari Vall d'Hebron) ; Tabernero, David (Hospital Universitari Vall d'Hebron) ; Cortese, Maria Francesca (Hospital Universitari Vall d'Hebron) ; Gregori i Font, Josep (Roche Diagnostics SL) ; Casillas, Rosario (Hospital Universitari Vall d'Hebron) ; Riveiro Barciela, Mar (Universitat Autònoma de Barcelona. Departament de Medicina) ; Godoy, Cristina (Hospital Universitari Vall d'Hebron) ; Sopena, Sara (Hospital Universitari Vall d'Hebron) ; Rando, Ariadna (Hospital Universitari Vall d'Hebron) ; Yll, Marçal (Hospital Universitari Vall d'Hebron) ; Lopez Martinez, Rosa (Hospital Universitari Vall d'Hebron) ; Quer Sivila, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteban, Rafael (Esteban Mur) (Universitat Autònoma de Barcelona. Departament de Medicina) ; Buti, Maria (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez Frías, Francisco (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
To detect hyper-conserved regions in the hepatitis B virus (HBV) X gene (HBX) 5' region that could be candidates for gene therapy. The study included 27 chronic hepatitis B treatment-naive patients in various clinical stages (from chronic infection to cirrhosis and hepatocellular carcinoma, both HBeAg-negative and HBeAg-positive), and infected with HBV genotypes A-F and H. [...]
2018 - 10.3748/wjg.v24.i19.2095
World Journal of Gastroenterology, Vol. 24 (may 2018) , p. 2095-2107  

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1 Yll, M.
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