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Articles, 1 records found
Research literature, 1 records found
Articles 1 records found  
1.
19 p, 9.0 MB Osmostress-Induced Apoptosis in Xenopus Oocytes : Role of Stress Protein Kinases, Calpains and Smac/DIABLO / Ben Messaoud, Nabil (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Yue, Jicheng (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Valent, Daniel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Katzarova, Ilina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Hyperosmotic shock induces cytochrome c release and capase-3 activation in Xenopus oocytes, but the regulators and signaling pathways involved are not well characterized. Here we show that hyperosmotic shock induces rapid calpain activation and high levels of Smac/DIABLO release from the mitochondria before significant amounts of cytochrome c are released to promote caspase-3 activation. [...]
2015 - 10.1371/journal.pone.0124482
PLoS one, Vol. 10, Num. 4 (2015) , p. 1-19  

Research literature 1 records found  
1.
126 p, 3.6 MB New insights into the MAPK function in meiotic progression and the regulation of osmostress-induced apoptosis in Xenopus oocytes / Yue, Jicheng ; López Blanco, José Manuel, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
En el organismo modelo Xenopus laevis, los oocitos de estadio VI están parados indefinidamente en la profase (G2/M) de la meiosis I hasta que se produce una adecuada estimulación hormonal. Una red de regulación positiva alrededor de la cascada Mos/MEK/ERK asegura la maduración (GVBD) de los oocitos tras la estimulación con progesterona. [...]
In the model organism Xenopus laevis, oocytes at stage VI are standing in prophase (G2/M) of meiosis I indefinitely until proper hormone stimulation. A positive regulation network around the Mos/MEK/ERK cascade ensures the rapid maturation (GVBD) of the oocytes upon stimulation with progesterone. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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