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13 p, 1.8 MB Extracellular albumin covalently sequesters selenocompounds and determines cytotoxicity / Zheng, Wenyi (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Boada, Roberto (Universitat Autònoma Barcelona. Departament de Química) ; He, Riu (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Xiao, Tingting (Universitat Autònoma Barcelona. Departament de Química) ; Ye, Fei (Kungliga Tekniska högskolan. Division of Functional Nanomaterials) ; Simonelli, Laura (ALBA Laboratori de Llum de Sincrotró) ; Valiente Malmagro, Manuel (Universitat Autònoma de Barcelona. Departament de Química) ; Zhao, Ying (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Hassan, Moustapha (Karolinska Institute Stockholm. Department of Laboratory Medicine)
Selenocompounds (SeCs) are well-known nutrients and promising candidates for cancer therapy; however, treatment efficacy is very heterogeneous and the mechanism of action is not fully understood. Several SeCs have been reported to have albumin-binding ability, which is an important factor in determining the treatment efficacy of drugs. [...]
2019 - 10.3390/ijms20194734
International journal of molecular sciences, Vol. 20, issue 19 (Oct. 2019) , art. 4734  

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