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Plasma lipid profiles discriminate bacterial from viral infection in febrile children
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Wang, Xinzhu (Imperial College London) ;
Nijman, Ruud Gerard (Imperial College London) ;
Camuzeaux, Stephane (IRDB Building) ;
Sands, Caroline (IRDB Building) ;
Jackson, Heather R. (Imperial College London) ;
Kaforou, Myrsini (Imperial College London) ;
Emonts, Marieke (Great North Children's Hospital) ;
Herberg, Jethro A. (Imperial College London) ;
Maconochie, Ian (Imperial College NHS Healthcare Trust) ;
Carrol, Enitan (Liverpool Health Partners) ;
Paulus, Stéphane (Liverpool Health Partners) ;
Zenz, Werner (Medical University of Graz) ;
Van der Flier, Michiel (Radboud University Medical Center) ;
de Groot, Ronald C.A. (Radboud University Medical Center) ;
Martinon-Torres, Federico (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Schlapbach, Luregn (Queensland Children's Hospital) ;
Pollard, AJ. (University of Oxford and the NIHR Oxford Biomedical Research Centre) ;
Fink, Colin (University of Warwick) ;
Kuijpers, T. W. (Emma Children's Hospital Academic Medical Center) ;
Anderson, Suzanne T. B. (London School of Hygiene & Tropical Medicine) ;
Lewis, Matthew R. (IRDB Building) ;
Levin, Michael (Imperial College London) ;
McClure, Myra (Imperial College London) ;
Gormley, Stuart (Imperial College London) ;
Hamilton, Shea (Imperial College London) ;
Hourmat, Bernardo (Imperial College London) ;
Hoggart, Clive (Imperial College London) ;
Sancho Shimizu, Vanessa (Imperial College London) ;
Wright, Victoria (Imperial College London) ;
Abdulla, Amina F. (Imperial College London) ;
Agapow, Paul Michael (Imperial College London) ;
Bartlett, Maeve (Imperial College London) ;
Bellos, Evangelos (Imperial College London) ;
Eleftherohorinou, Hariklia (Imperial College London) ;
Galassini, Rachel (Imperial College London) ;
Inwald, David (Imperial College London) ;
Mashbat, Meg (Imperial College London) ;
Menikou, Stephanie (Imperial College London) ;
Mustafa, Sobia (Imperial College London) ;
Nadel, Simon (Imperial College London) ;
Rahman, Rahmeen (Imperial College London) ;
Thakker, Clare (Imperial College London) ;
Coin, Lachlan (Imperial College London) ;
Bokhandi, Sumit S. (Poole Hospital NHS Foundation Trust) ;
Power, Sue (Poole Hospital NHS Foundation Trust) ;
Barham, Heather (Poole Hospital NHS Foundation Trust) ;
Pathan, Nazima (Cambridge University Hospitals NHS Trust) ;
Ridout, Jenna (Cambridge University Hospitals NHS Trust) ;
White, Deborah K. (Cambridge University Hospitals NHS Trust) ;
Thurston, Sarah (Cambridge University Hospitals NHS Trust) ;
Faust, Saul (University Hospital Southampton) ;
Patel, Sanjay Valabh (University Hospital Southampton) ;
McCorkell, Jenni (University Hospital Southampton) ;
Davies, Patrick (Nottingham University Hospital NHS Trust) ;
Crate, Lindsay (Nottingham University Hospital NHS Trust) ;
Navarra, Helen (Nottingham University Hospital NHS Trust) ;
Carter, Stephanie (Nottingham University Hospital NHS Trust) ;
Ramaiah, Raghu (University Hospitals of Leicester NHS Trust) ;
Patel, Rekha (University Hospitals of Leicester NHS Trust) ;
Tuffrey, Catherine (Portsmouth Hospitals NHS Trust) ;
Gribbin, Andrew (Portsmouth Hospitals NHS Trust) ;
McCready, Sharon (Portsmouth Hospitals NHS Trust) ;
Peters, Mark (Great Ormond Street Hospital for Children (Londres)) ;
Hardy, Katie (Great Ormond Street Hospital for Children (Londres)) ;
Standing, Fran (Great Ormond Street Hospital for Children (Londres)) ;
O'Neill, Lauren (Great Ormond Street Hospital for Children (Londres)) ;
Abelake, Eugenia (Great Ormond Street Hospital for Children (Londres)) ;
Deep, Akash (King's College Hospital NHS Foundation Trust) ;
Nsirim, Eniola (King's College Hospital NHS Foundation Trust) ;
Willis, Louise (Oxford University Hospitals NHS Foundation Trust) ;
Young, Zoe (Oxford University Hospitals NHS Foundation Trust) ;
Royad, C. (Kettering General Hospital NHS Foundation Trust) ;
White, Sonia (Kettering General Hospital NHS Foundation Trust) ;
Fortune, Peter-Marc (Central Manchester NHS Trust) ;
Hudnott, Phil (Central Manchester NHS Trust) ;
Álvez González, Fernando (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Barral-Arca, Ruth (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Cebey-López, Miriam (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Curras-Tuala, MJ. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
García, Natalia (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Vicente, Luisa García (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Gómez-Carballa, Alberto (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Gomez-Rial, Jose (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Grela Beiroa, Andrea (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Justicia-Grande, Antonio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Iglesias, Pilar Leboráns (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Martinez-Santos, Alba-Elena (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
MartinónTorres, Nazareth (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Sánchez, José María (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Morillo Gutiérrez, Beatriz (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Pérez, Belén Mosquera (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Pacheco, Pablo Obando (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Pardo-Seco, Jacobo (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Pischedda, Sara (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Rivero Calle, Irene (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Rodríguez-Tenreiro, Carmen (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Redondo Collazo, Lorenzo (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Ellacuriagal, Antonio Salas (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Serén Fernández, Sonia (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Silva, María Del Sol Porto (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Vega, Ana Karina (Universidade de Santiago de Compostela (USC)) ;
Vilanova-Trillo, Lucía (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Salas, Antonio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Reyes, Susana Beatriz (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
León-León, María Cruz (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Mingorance, Álvaro Navarro (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Barrios, Xavier Gabaldó (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Oñate Vergara, Eider (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Concha-Torre, Andres (Hospital Universitario Central de Asturias) ;
Vivanco, Ana (Hospital Universitario Central de Asturias) ;
Fernández, Reyes (Hospital Universitario Central de Asturias) ;
Giménez-Sánchez, Francisco (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Forte, Miguel Sánchez (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Rojo, Pablo (Hospital 12 de Octubre (Madrid)) ;
Contreras, J. Ruiz (Hospital 12 de Octubre (Madrid)) ;
Palacios, Alba (Hospital 12 de Octubre (Madrid)) ;
Ibarrondo, Cristina Epalza (Hospital 12 de Octubre (Madrid)) ;
Cooke, Elizabeth Fernández (Hospital 12 de Octubre (Madrid)) ;
Navarro, Marisa (Hospital General Universitario Gregorio Marañón) ;
Álvarez, Cristina Álvarez (Hospital General Universitario Gregorio Marañón) ;
Lozano, María José (Hospital General Universitario Gregorio Marañón) ;
Carreras, Eduardo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Brió Sanagustín, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Neth, Olaf (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Padilla, Ma del Carmen Martínez (Complejo Hospitalario de Jaén) ;
Tato, Luis Manuel Prieto (Hospital Universitario de Getafe (Madrid)) ;
Guillén, Sara (Hospital Universitario de Getafe (Madrid)) ;
Fernandez Silveira, Laura (Hospital Universitari i Politècnic La Fe (València)) ;
Moreno, David (Hospital Regional Universitario Carlos Haya (Málaga)) ;
van Furth, Marceline (Vrije Universiteit University Medical Center) ;
Boeddha, Navin P. (Sophia Children's Hospital) ;
Driessen, Gertjan Jan A. (Sophia Children's Hospital) ;
Hazelzet, Jan (Sophia Children's Hospital) ;
Pajkrt, Dasja (Emma Children's Hospital Academic Medical Center) ;
Sanders, Elisabeth A. M. (Wilhelmina Children's Hospital) ;
van de Beek, Diederik (University of Amsterdam) ;
van der Ende, Arie (University of Amsterdam) ;
Philipsen, H.L.A. (Vrije Universiteit University Medical Center) ;
Adeel, Abdul O.A. (Kennemer Gasthuis) ;
Breukels, Meike A. (Elkerliek Hospital) ;
Brinkman, Daniëlle M.C. (Alrijne Hospital) ;
de Korte, Carla C.M.M. (Beatrix Hospital) ;
de Vries, Esther (Diakonessenhuis) ;
de Waal, Wouter J. (Maasziekenhuis Pantein) ;
Dekkers, Roel (Maasziekenhuis Pantein) ;
Dings-Lammertink, Anouk (Gelre Hospitals) ;
Doedens, Rienus A. (Martini Hospital) ;
Donker, AlbertineE. (Maxima Medical Center) ;
Dousma, Mieke (Gemini Hospital) ;
Faber, Tina E. (Medical Center Leeuwarden) ;
Gerrits, Gerardus Peter Jm M. (Canisius-Wilhelmina Hospital) ;
Gerver, Jan A.M. (Rode Kruis Hospital) ;
Heidema, Jojanneke (St. Antonius Hospital) ;
Veen, J. Homan-van der (Deventer Hospital) ;
Jacobs, Monique A.M. (Slingeland Hospital) ;
Jansen, Nicolaas Johannes Georgius (Wilhelmina Children's Hospital) ;
Kawczynski, Pawel (Refaja Hospital) ;
Klucovska, Kristine (Bethesda Hospital) ;
Kneyber, Martin Christiaan Jacques (Beatrix Children's hospital) ;
Koopman-Keemink, Yvonne (Juliana Children's Hospital) ;
Langenhorst, Veerle J. (Isala Hospital) ;
Leusink, José (Bernhoven Hospital) ;
Loza, Bettina F. (VieCuri Medical Center) ;
Merth, Istvan T. (Ziekenhuisgroep Twente) ;
Miedema, Carien J. (Catharina Hospital) ;
Neeleman, Chris (Vrije Universiteit University Medical Center) ;
Noordzij, Jeroen G. (Reinier de Graaf Gasthuis) ;
Obihara, Charlie C.C. (ETZ Elisabeth) ;
van Overbeek - van Gils, A. Lidy T. (Scheper Hospital) ;
Poortman, Geriska H. (St. Jansdal Hospital) ;
Potgieter, Steph T. (Laurentius Hospital) ;
Potjewijd, Joke (Isala Diaconessenhuis) ;
Rosias, Philippe P.R. (Zuyderland Medical Center) ;
Sprong, Tom (Canisius-Wilhelmina Hospital) ;
ten Tussher, Gavin W. (Westfriesgasthuis) ;
Thio, Bernard J. (Medisch Spectrum Twente) ;
Tramper-Stranders, Gerdien A. (St. Franciscus Gasthuis) ;
van Deuren, M. (Vrije Universiteit University Medical Center) ;
van der Meer, H. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
van Kuppevelt, A.J.M. (Streekziekenhuis Koningin Beatrix) ;
van Wermeskerken, A.M. (Flevo Hospital) ;
Verwijs, W.A. (Zuwe Hofpoort Hospital) ;
Wolfs, T.F.W. (Newcastle University) ;
Agyeman, Philipp (University of Bern) ;
Aebi, C. (University of Bern) ;
Berger, C. (University Children's Hospital Zurich) ;
Giannoni, E. (Lausanne University Hospital) ;
Stocker, M. (Children's Hospital Lucerne) ;
Posfay-Barbe, K.M. (Geneva University Hospitals) ;
Heininger, U. (University of Basel Children's Hospital) ;
Bernhard-Stirnemann, S. (Children's Hospital Aarau) ;
Niederer-Loher, A. (Children's Hospital of Eastern Switzerland St. Gallen) ;
Kahlert, C. (Children's Hospital of Eastern Switzerland St. Gallen) ;
Hasters, P. (University Hospital Zurich (Suïssa)) ;
Relly, C. (University Children's Hospital Zurich) ;
Baer, W. (Children's Hospital Chur) ;
Frederick, H. (Alder Hey Children's Hospital) ;
Jennings, R. (Alder Hey Children's Hospital) ;
Johnston, J. (Alder Hey Children's Hospital) ;
Kenwright, R. (Alder Hey Children's Hospital) ;
Pinnock, Elli (University of Warwick) ;
Agbeko, R. (Imperial College NHS Healthcare Trust) ;
Secka, Fatou (London School of Hygiene & Tropical Medicine) ;
Bojang, Kalifa (London School of Hygiene & Tropical Medicine) ;
Sarr, Isatou (London School of Hygiene & Tropical Medicine) ;
Kebbeh, Ngange (London School of Hygiene & Tropical Medicine) ;
Sey, Gibbi (London School of Hygiene & Tropical Medicine) ;
Momodou, None ;
khan, Saidy (London School of Hygiene & Tropical Medicine) ;
Cole, Fatoumata (London School of Hygiene & Tropical Medicine) ;
Thomas, Gilleh (London School of Hygiene & Tropical Medicine) ;
Antonio, Martin (London School of Hygiene & Tropical Medicine) ;
Klobassa, Daniela S. (University Medical Center Utrecht) ;
Binder, Alexander (University Medical Center Utrecht) ;
Schweintzger, Nina (University Medical Center Utrecht) ;
Sagmeister, Manfred (University Medical Center Utrecht) ;
Baumgart, Hinrich (Medical University Graz) ;
Baumgartner, Markus (General Hospital of Steyr) ;
Behrends, Uta (Technische Universität München (TUM)) ;
Biebl, Ariane (Medical Faculty of the Johannes Kepler University) ;
Birnbacher, Robert (LKH Villach) ;
Blanke, Jan-Gerd (Hospital Ludmillenstift) ;
Boelke, Carsten (Hospital for Children's and Youth Medicine. Oberschwabenklinik) ;
Breuling, Kai (Technische Universität München (TUM)) ;
Brunner, Jürgen (Medical University Innsbruck) ;
Buller, Maria (Sana Hanse-Klinikum Wismar) ;
Dahlem, Peter (Medical Center Coburg) ;
Dietrich, Beate (University Medicine Rostock) ;
Eber, Ernst (Medical University Graz) ;
Elias, Johannes (University of Würzburg) ;
Emhofer, Josef (General Hospital of Steyr) ;
Etschmaier, Rosa (Medical University Graz) ;
Farr, Sebastian (Orthopedic Hospital Speising) ;
Girtler, Ylenia (Regional Hospital Bolzano) ;
Grigorow, Irina (General Hospital Hochsteiermark/Leoben) ;
Heimann, Konrad (RWTH Aachen) ;
Ihm, Ulrike (Donauspital Vienna) ;
Jaros, Zdenek (General Public Hospital) ;
Kalhoff, Hermann (Pediatric Clinic Dortmund) ;
Kaulfersch, Wilhelm (Klinikum Klagenfurt am Wörthersee) ;
Kemen, Christoph (Catholic Children's Hospital Wilhelmstift) ;
Klocker, Nina (Krankenhaus Dornbirn) ;
Köster, Bernhard (Maerkische Kliniken) ;
Kohlmaier, B. (Medical University Graz) ;
Komini, Eleni (Schwarzwald-Baar-Hospital) ;
Kramer, Lydia (Technische Universität München (TUM)) ;
Neubert, Antje (University Hospital Erlangen (Alemanya)) ;
Ortner, Daniel (Medical University of Salzburg) ;
Pescollderungg, Lydia (Regional Hospital Bolzano) ;
Pfurtscheller, Klaus (Medical University Graz) ;
Reiter, Karl (Ludwig-Maximilians-Universitaet) ;
Ristic, Goran (Mother and Child Health Care Institute of Serbia) ;
Rödl, Siegfried (Medical University Graz) ;
Sellner, Andrea (Medical University Graz) ;
Sonnleitner, Astrid (Medical University Graz) ;
Sperl, Matthias (Medical University Graz) ;
Stelzl, Wolfgang (Landeskrankenhaus Feldkirch) ;
Till, Holger Karl H. (Medical University Graz) ;
Trobisch, Andreas (Medical University Graz) ;
Vierzig, Anne (University of Cologne) ;
Vogel, Ulrich (Medical University Graz) ;
Weingarten, Christina (Department of Pediatrics and Adolescent Medicine Wilheminenspital) ;
Welke, Stefanie (Municipal Hospital Karlsruhe) ;
Wimmer, Andreas (Hospital of the Sisters of Mercy Ried) ;
Wintergerst, Uwe (Hospital St. Josef) ;
Wüller, Daniel (Christophorus Kliniken Coesfeld Clinic for Pediatrics) ;
Zaunschirm, Andrew (Karl Landsteiner University of Health Sciences) ;
Ziuraite, Ieva (Children's Hospital) ;
Žukovskaja, Veslava (Children's Hospital) ;
Universitat Autònoma de Barcelona
Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis of infection. [...]
2019 -  10.1038/s41598-019-53721-1
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 17714
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15 p, 1.7 MB |
Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
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Borghini, Lisa (Genome Institute of Singapore) ;
Png, Eileen (Genome Institute of Singapore) ;
Binder, Alexander (Medical University of Graz) ;
Wright, Victoria (Imperial College London) ;
Pinnock, Ellie (University of Warwick) ;
de Groot, Ronald (Radboud University Medical Center) ;
Hazelzet, Jan (University Medical Center) ;
Emonts, Marieke (Great North Children's Hospital) ;
van der Flier, Michiel (Radboud University Medical Center) ;
Schlapbach, Luregn J. (University of Bern) ;
Anderson, Suzanne (Medical Research Council Unit Gambia) ;
Secka, Fatou (Medical Research Council Unit Gambia) ;
Salas, Antonio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Fink, Colin (University of Warwick) ;
Carrol, Enitan D. (University of Liverpool) ;
Pollard, Andrew J. (University of Oxford and the NIHR Oxford Biomedical Research Centre) ;
Coin, Lachlan J. (The University of Queensland) ;
Kuijpers, Taco W. (Emma Children's Hospital Academic Medical Center) ;
Martinon-Torres, Federico (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Zenz, Werner (Medical University of Graz) ;
Levin, Michael (Imperial College London) ;
Hibberd, Martin L. (London School of Hygiene & Tropical Medicine) ;
Davila, Sonia (Duke-NUS Medical School) ;
Gormley, Stuart (Imperial College London) ;
Hamilton, Shea (Imperial College London) ;
Herberg, Jethro (Imperial College London) ;
Hourmat, Bernardo (Imperial College London) ;
Hoggart, Clive (Imperial College London) ;
Kaforou, Myrsini (Imperial College London) ;
Sancho-Shimizu, Vanessa (Imperial College London) ;
Abdulla, Amina (Imperial College London) ;
Agapow, Paul (Imperial College London) ;
Bartlett, Maeve (Imperial College London) ;
Bellos, Evangelos (Imperial College London) ;
Eleftherohorinou, Hariklia (Imperial College London) ;
Galassini, Rachel (Imperial College London) ;
Inwald, David (Imperial College London) ;
Mashbat, Meg (Imperial College London) ;
Menikou, Stefanie (Imperial College London) ;
Mustafa, Sobia (Imperial College London) ;
Nadel, Simon (Imperial College London) ;
Rahman, Rahmeen (Imperial College London) ;
Thakker, Clare (Imperial College London) ;
Bokhandi, S. (Poole Hospital NHS Foundation Trust) ;
Power, Sue (Poole Hospital NHS Foundation Trust) ;
Barham, Heather (Poole Hospital NHS Foundation Trust) ;
Pathan, N. (Cambridge University Hospitals NHS Trust) ;
Ridout, Jenna (Cambridge University Hospitals NHS Trust) ;
White, Deborah (Cambridge University Hospitals NHS Trust) ;
Thurston, Sarah (Cambridge University Hospitals NHS Trust) ;
Faust, S. (University Hospital Southampton) ;
Patel, S. (University Hospital Southampton) ;
McCorkell, Jenni (University Hospital Southampton) ;
Davies, P. (Nottingham University Hospital NHS Trust) ;
Cratev, Lindsey (Nottingham University Hospital NHS Trust) ;
Navarra, Helen (Nottingham University Hospital NHS Trust) ;
Carter, Stephanie (Nottingham University Hospital NHS Trust) ;
Ramaiah, R. (University Hospitals of Leicester NHS Trust) ;
Patel, Rekha (University Hospitals of Leicester NHS Trust) ;
Tuffrey, Catherine (Portsmouth Hospitals NHS Trust) ;
Gribbin, Andrew (Portsmouth Hospitals NHS Trust) ;
McCready, Sharon (Portsmouth Hospitals NHS Trust) ;
Peters, Mark (Portsmouth Hospitals NHS Trust) ;
Hardy, Katie (Portsmouth Hospitals NHS Trust) ;
Standing, Fran (Portsmouth Hospitals NHS Trust) ;
O'Neill, Lauren (Portsmouth Hospitals NHS Trust) ;
Abelake, Eugenia (Portsmouth Hospitals NHS Trust) ;
Deep, Akash (King's College Hospital NHS Foundation Trust) ;
Nsirim, Eniola (King's College Hospital NHS Foundation Trust) ;
Willis, Louise (University of Oxford) ;
Young, Zoe (University of Oxford) ;
Royad, C. (Kettering General Hospital NHS Foundation Trust) ;
White, Sonia (Kettering General Hospital NHS Foundation Trust) ;
Fortune, P.M. (Central Manchester NHS Trust) ;
Hudnott, Phil (Central Manchester NHS Trust) ;
González, Férnando Álvez (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Barral-Arca, Ruth (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Cebey-López, Miriam (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Curras-Tuala, María José (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
García, Natalia (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Vicente, Luisa García (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Gómez-Carballa, Alberto (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Rial, José Gómez (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Beiroa, Andrea Grela (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Grande, Antonio Justicia (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Iglesias, Pilar Leboráns (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Santos, Alaba Elena Martínez (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Martinón-Torres, Nazareth (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Sánchez, José María Martinón (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Pérez, Belén Mosquera (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Pacheco, Pablo Obando (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Pardo-Seco, Jacobo (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Pischedda, Sara (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Calle, Irene Rivero (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Rodríguez-Tenreiro, Carmen (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Redondo-Collazo, Lorenzo (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Fernández, Sonia Serén (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Silva, María del Sol Porto (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Vega, Ana (Universidade de Santiago de Compostela (USC)) ;
Reyes, Susana Beatriz (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
León, María Cruz León (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Mingorance, Álvaro Navarro (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Barrios, Xavier Gabaldó (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Vergara, Eider Oñate (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Torre, Andrés Concha (Hospital Universitario Central de Asturias) ;
Vivanco, Ana (Hospital Universitario Central de Asturias) ;
Fernández, Reyes (Hospital Universitario Central de Asturias) ;
Sánchez, Francisco Giménez (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Forte, Miguel Sánchez (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Rojo, Pablo (Hospital 12 de Octubre (Madrid)) ;
Contreras, J.Ruiz (Hospital 12 de Octubre (Madrid)) ;
Palacios, Alba (Hospital 12 de Octubre (Madrid)) ;
Navarro, Marisa (Hospital General Universitario Gregorio Marañón) ;
Álvarez, Cristina Álvarez (Hospital General Universitario Gregorio Marañón) ;
Lozano, María José (Hospital General Universitario Gregorio Marañón) ;
Carreras, Eduardo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Brió Sanagustín, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Neth, Olaf (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Padilla, Ma del Carmen Martínez (Complejo Hospitalario de Jaén) ;
Tato, Luis Manuel Prieto (Hospital Universitario de Getafe (Madrid)) ;
Guillén, Sara (Hospital Universitario de Getafe (Madrid)) ;
Silveira, Laura Fernández (Hospital Universitari i Politècnic La Fe (València)) ;
Moreno, David (Hospital Regional Universitario Carlos Haya (Málaga)) ;
van Furth, A.M.Tutu (Vrije Universiteit University Medical Center) ;
van der Flier, Michiel (Radboud University Medical Center) ;
Boeddha, N.P. (University Medical Center) ;
Driessen, G.J.A. (University Medical Center) ;
Pajkrt, D. (Emma Children's Hospital Academic Medical Center) ;
Sanders, E.A.M. (University Medical Center Utrecht - Wilhelmina Children's Hospital) ;
van de Beek, D. (University of Amsterdam) ;
van der Ende, A. (University of Amsterdam) ;
Philipsen, H.L.A. (Radboud University Medical Center) ;
Adeel, A.O.A. (Kennemer Gasthuis) ;
Breukels, M.A. (Elkerliek Hospital) ;
Brinkman, Daniëlle M.C (Alrijne Hospital) ;
de Korte, C.C.M.M. (Beatrix Hospital) ;
de Vries, E. (Jeroen Bosch Hospital) ;
de Waal, W.J. (Diakonessenhuis) ;
Dekkers, R. (Maasziekenhuis Pantein) ;
Dings-Lammertink, A. (Gelre Hospitals) ;
Doedens, R.A. (Martini Hospital) ;
Donker, A.E. (Maxima Medical Center) ;
Dousma, M. (Gemini Hospital) ;
Faber, T.E. (Medical Center Leeuwarden) ;
Gerrits, G.P.J.M. (Canisius-Wilhelmina Hospital) ;
Gerver, J.A.M. (Rode Kruis Hospital) ;
Heidema, J. (St. Antonius Hospital) ;
Homan-van der Veen, J. (Deventer Hospital) ;
Jacobs, M.A.M. (Slingeland Hospital) ;
Jansen, N.J.G. (University Medical Center Utrecht - Wilhelmina Children's Hospital) ;
Kawczynski, P. (Refaja Hospital) ;
Klucovska, K. (Bethesda Hospital) ;
Kneyber, M.C.J. (University Medical Center Groningen. Beatrix Children's hospital) ;
Koopman-Keemink, Y. (Haga Hospital - Juliana Children's Hospital) ;
Langenhorst, V.J. (Isala Hospital) ;
Leusink, J. (Bernhoven Hospital) ;
Loza, B.F. (VieCuri Medical Center) ;
Merth, I.T. (Ziekenhuisgroep Twente) ;
Miedema, C.J. (Catharina Hospital) ;
Neeleman, C. (Radboud University Medical Center) ;
Noordzij, J.G. (Reinier de Graaf Gasthuis) ;
Obihara, C.C. (ETZ Elisabeth) ;
van Overbeek-van Gils, A.L.T. (Scheper Hospital) ;
Poortman, G.H. (St. Jansdal Hospital) ;
Potgieter, S.T. (Laurentius Hospital) ;
Potjewijd, J. (Isala Diaconessenhuis) ;
Rosias, P.P.R. (Zuyderland Medical Center) ;
Sprong, T. (Canisius-Wilhelmina Hospital) ;
ten Tussher, G.W. (Westfriesgasthuis) ;
Thio, B.J. (Medisch Spectrum Twente) ;
Tramper-Stranders, G.A. (St. Franciscus Gasthuis) ;
van Deuren, M. (Radboud University Medical Center) ;
van der Meer, H. (Vrije Universiteit University Medical Center) ;
van Kuppevelt, A.J.M. (Streekziekenhuis Koningin Beatrix) ;
van Wermeskerken, A.M. (Flevo Hospital) ;
Verwijs, W.A. (Zuwe Hofpoort Hospital) ;
Wolfs, T.F.W. (University Medical Center Utrecht - Wilhelmina Children's Hospital) ;
Agyeman, Philipp (University of Bern) ;
Aebi, Christoph (University of Bern) ;
Berger, Christoph (University Children's Hospital Zurich) ;
Giannoni, Eric (Infectious Diseases Service. Lausanne University Hospital) ;
Stocker, Martin (Department of Pediatrics. Children's Hospital Lucerne) ;
Posfay-Barbe, Klara M. (Geneva University Hospitals) ;
Heininger, Ulrich (Universitäts-Kinderspital beider Basel. Abt für Infektiologie) ;
Bernhard-Stirnemann, Sara (Children's Hospital Aarau) ;
Niederer-Loher, A. (Children's Hospital of Eastern Switzerland St. Gallen) ;
Kahlert, Christian (Children's Hospital of Eastern Switzerland St. Gallen) ;
Hasters, Paul (University Hospital Zurich (Suïssa)) ;
Relly, Christa (University Children's Hospital Zurich) ;
Baer, Walter (Children's Hospital Chur) ;
Paulus, Stéphane (Alder Hey Children's Hospital) ;
Frederick, Hannah (Alder Hey Children's Hospital) ;
Jennings, Rebecca (Alder Hey Children's Hospital) ;
Johnston, Joanne (Alder Hey Children's Hospital) ;
Kenwright, Rhian (Alder Hey Children's Hospital) ;
Agbeko, Rachel (Great North Children's Hospital) ;
Bojang, Kalifa (Medical Research Council Unit Gambia) ;
Sarr, Isatou (Medical Research Council Unit Gambia) ;
Kebbeh, Ngane (Medical Research Council Unit Gambia) ;
Sey, Gibbi (Medical Research Council Unit Gambia) ;
Saidykhan, Momodou (Medical Research Council Unit Gambia) ;
Cole, Fatoumatta (Medical Research Council Unit Gambia) ;
Thomas, Gilleh (Medical Research Council Unit Gambia) ;
Antonio, Martin (Medical Research Council Unit Gambia) ;
Walcher, Wolfgang (Medical University of Graz) ;
Geishofer, Gotho (Medical University of Graz) ;
Klobassa, Daniela (Medical University of Graz) ;
Martin, Müller (Medical University of Graz) ;
Pfurtscheller, Klaus (Medical University of Graz) ;
Reiter, Karl (Kinderklinik der LMU München am Dr. von Haunerschen Kinderspital) ;
Rödl, Siegfried (Medical University of Graz) ;
Zobel, Gerfried (Medical University of Graz) ;
Zöhrer, Bettina (Medical University of Graz) ;
Töpke, Bärbel (Ostalb-Klinikum) ;
Fucik, Peter (Krankenhaus Amstetten) ;
Gabriel, Markwart (Klinikum Aschaffenburg) ;
Penzien, Johann M. (Zentralklinikum Kinderkliniken) ;
Diab, Gedeon (Kreiskrankenhaus Bad Hersfeld) ;
Miething, Robert (Diakonie-Krankenhaus) ;
Deeg, K.H. (Klinikum Bamberg) ;
Hammer, Jürg (Universitäts-Kinderspital beider Basel) ;
Heininger, Ulrich (Universitäts-Kinderspital beider Basel) ;
Varnholt, Verena (Uni-Klinikum Charité) ;
Schmidt, Andreas (St.-Agnes-Hospital) ;
Bindl, Lutz (Rheinische Friedrich-Wilhelms-Universität) ;
Sillaber, Ursula (Landeskrankenhaus Bregenz. Abt für Innere Medizin) ;
Huemer, Christian (Landeskrankenhaus Bregenz. Abt für Kinderheilkunde) ;
Meier, Primrose (Zentralkrankenhaus Links d. Weser) ;
Simic-Schleicher, G. (Zentralkrankenhaus Bremen-Nord) ;
Markart, Markus (Ospedale di Bressanone) ;
Pfau, Eberhard (DRK-Krankenhaus Chemnitz-Rabenstein) ;
Broede, Hans (Klinikum Lippe-Detmold GmbH) ;
Ausserer, Bernd (Krankenhaus Dornbirn) ;
Kalhoff, Hermann (Städt. Kliniken Dortmund) ;
Arpe, Volker (St. Marien-Hospital Düren-Birkesdorf) ;
Schweitzer-Krantz, Susanne (Evangelisches Krankenhaus) ;
Kasper, Johannes-Martin (St. Georg Klinikum Eisenach gGmbH) ;
Loranth, Kathrin (Krankenhaus der Barmherzigen Brüder) ;
Bittrich, Hans J. (Helios Klinikum Erfurt) ;
Simma, Burkhard (Landeskrankenhaus Feldkirch) ;
Klinge, Jens (Klinikum Fürth) ;
Fedlmaier, Michael (Klinikum Garmisch-Partenkirchen) ;
Weigand, Nicola (Klinikum Justus-Liebig-Uni-O) ;
Herting, Egbert (Georg-August Universitäts-Kinderklinik) ;
Grube, Regina (University Klinik für Neurologie) ;
Fusch, Christoph (Klinikum d. Ernst-Moritz-Arndt-Universität) ;
Gruber, Alois (Krankenhaus der Schulschwestern Grieskirchen) ;
Schimmel, Ulf (Allg. Krankenhaus Hagen GmbH) ;
Knaufer-Schiefer, Suzanne (Ohrekreis-Klinikum) ;
Lässig, Wolfgang (Städt. Krankenhaus Martha-Maria Halle-Dölau gGmbH) ;
Hennenberger, Axel (Kinderkrankenhaus Wilhelmstift) ;
von der Wense, Axel (Altonaer Kinderkrankenhaus) ;
Tillmann, Roland (Klinikum Kreis Herford) ;
Schwarick, Jürgen (Kreiskrankenhaus Herzberg) ;
Sitzmann, Friedrich C. (University Klinik für Kinder- und Jugendmedizin) ;
Streif, Werner (University Klinik für Kinder- und Jugendheilkunde Innsbruck) ;
Müller, Herbert (Klinik Robert-Weixler-Strasse) ;
Kurnik, Peter (Landeskrankenhaus Klagenfurt) ;
Groneck, Peter (Kinderklinik der Stadt Köln) ;
Weiss, Ute (Achenbach-Kreiskrankenhaus) ;
Gröblacher-Roth, Helene (Landeskrankenhaus Krems a. d. Donau) ;
Bensch, Jürgen (Vinzentius-Krankenhaus) ;
Moser, Reinhard (Landeskrankenhaus Leoben) ;
Schwarz, Rudolf (Landes-Kinderklinik Linz) ;
Lenz, Kurt (Konventhospital der Barmherzigen Brüder) ;
Hofmann, Thomas (Evangelisches Krankenhaus) ;
Göpel, Wolfgang (Med. Universität zu Lübeck) ;
Schulz, Dietrich (Städtisches Klinikum Lüneburg) ;
Berger, Thomas (Kantonspital Luzern) ;
Hauser, Erwin (Landeskrankenhaus Mödling) ;
Förster, Kai Martin (Städt. Krankenhaus Harlaching) ;
Peters, Jochen (Kinderklinik der TU München) ;
Nicolai, T homas (Kinderklinik im Dr. v. Haunerschen Kinderspital) ;
Kumlien, Björn. (Kinderklinik des Dritten Ordens) ;
Beckmann, Regina (Dietrich-Bonhoeffer-Klinikum) ;
Seitz, Christiane (FEK-Friedrich-Ebert-Krankenhaus. Neumünster GmbH) ;
Hüseman, D. (Ruppiner Kliniken GmbH) ;
Schürmann, Roland (Städt. Kliniken Neuss Lukaskrankenhaus GmbH) ;
Ta, Van Hop (Evangelisches Krankenhaus) ;
Weikmann, Eckart (Landeskrankenhaus Oberwart) ;
Evert, W. (Städt. Kliniken Offenbach) ;
Hautz, Jürgen (Klinikum Offenburg) ;
Seidenberg, Jürgen (Elisabeth-Kinderkrankenhaus) ;
Wocko, Lucia (Krankenhaus Oranienburg) ;
Luigs, Petra (St.Vincenz-Krankenhaus Frauen- u. Kinderklinik) ;
Reiter, Hans-Ludwig (Klinik für Kinder und Jugendliche am Städtischen Klinikum) ;
Quietzach, J. (Vogtland-Klinikum Plauen GmbH) ;
König, Michael (Oberschwaben Klinik gGmbH) ;
Herrmann, Johanna (Kreiskrankenhaus Rendsburg) ;
Mitter, Horst (Krankenhaus der Barmherzigen Schwestern Ried) ;
Seidler, Ekkehard (Kreiskrankenhaus Obergöltzsch-Rodewisch) ;
Maak, Bernhard (Thüringen-Klinik "Georgius Agricola" gGmbH) ;
Sperl, Wolfgang (Landeskrankenanstalten Salzburg) ;
Zwiauer, Karl (Landesklinikum Sankt Pölten) ;
Meissl, Manfred (Landeskrankenhaus Schärding) ;
Koch, Reinhard (Leopoldina-Krankenhaus) ;
Cremer, Manfred (DRK-Kinderklinik Siegen) ;
Breuer, H.A. (Städt. Klinikum Solingen) ;
Görke, W. (Johanniter Kinderklinik) ;
Nossal, Robert (Olga Hospital Stuttgart) ;
Pernice, Walter (Kreiskrankenhaus Torgau) ;
Brangenberg, alf. (Klinikum Traunstein) ;
Salzer, Hans R. (Landeskrankenhaus Tulln) ;
Koch, Hartmut (St. Marien-Hospital) ;
Schaller, Gerhard (Landeskrankenhaus Villach) ;
Paky, Franz (Landeskrankenhaus Vöcklabruck) ;
Straßer, Friedrich (Klinikum Weiden) ;
Eitelberger, Franz (Krankenhaus der Barmherzigen Schwestern v. heiligen Kreuz) ;
Sontheimer, D. (Harz-Klinikum Wernigerode GmbH) ;
Lischka, Andreas (Wilhelminenspital Wien) ;
Kronberger, Martina (St. Anna Kinderspital) ;
Dilch, Alfred (Gottfried von Preyersches Kinderspital der Stadt Wien) ;
Scheibenpflug, Christian (Donauspital im SMZ-Ost der Stadt Wien) ;
Bruckner, Robert (Krankenhaus Wiener Neustadt) ;
Mahler, Klaus (St. Elisabeth Krankenhaus) ;
Runge, Klaus (Zentrum für Kinder- und Jugendmedizin) ;
Kunze, Wolfgang (Krankenhaus Muldentalkreis Wurzen) ;
Schermann, Peter (Krankenhaus Zwettl) ;
Universitat Autònoma de Barcelona
Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. [...]
2019 - 10.1038/s41598-019-43292-6
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 6966
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3 p, 1.6 MB |
The PRALINE database : protein and Rna humAn singLe nucleotIde variaNts in condEnsates
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Vandelli, Andrea (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Arnal, Magdalena (University Sapienza Rome) ;
Monti, Michele (Istituto Italiano di Tecnologia) ;
Fiorentino, Jonathan (Istituto Italiano di Tecnologia) ;
Broglia, Laura (Istituto Italiano di Tecnologia) ;
Colantoni, Alessio (University Sapienza Rome) ;
Sánchez de Groot, Natalia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Armaos, Alexandros (Istituto Italiano di Tecnologia) ;
Tartaglia, Gian Gaetano (Istituto Italiano di Tecnologia)
Biological condensates are membraneless organelles with different material properties. Proteins and RNAs are the main components, but most of their interactions are still unknown. Here, we introduce PRALINE, a database for the interrogation of proteins and RNAs contained in stress granules, processing bodies and other assemblies including droplets and amyloids. [...]
2023 - 10.1093/bioinformatics/btac847
Bioinformatics, Vol. 39, Num.1 (January 2023) , art. btac847
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4.
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13 p, 4.6 MB |
Aβ40 Aggregation under Changeable Conditions
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Curto, Jofre Seira (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Fernández Gallegos, María Rosario (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Cladera i Cerdà, Josep (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Benseny Cases, Núria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Sánchez de Groot, Natalia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Homeostasis is crucial for cell function, and disturbances in homeostasis can lead to health disorders. Under normal conditions, intracellular pH is maintained between 7. 35 and 7. 45. Altered endosomal and lysosomal pH together with a general drop in brain pH are associated with the aggregation of amyloid-β-peptide (Aβ) and the development of Alzheimer's disease. [...]
2023 - 10.3390/ijms24098408
International journal of molecular sciences, Vol. 24, Issue 9 (May 2023) , art. 8408
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5.
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10 p, 1.6 MB |
Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions
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Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Chalancon, Guilhem (Medical Research Council. Laboratory of Molecular Biology) ;
Sánchez de Groot, Natalia (Medical Research Council. Laboratory of Molecular Biology) ;
Wuster, Arthur (Medical Research Council. Laboratory of Molecular Biology) ;
Babu, Madam M. (Medical Research Council. Laboratory of Molecular Biology)
Decoding the information in mRNA during protein synthesis relies on tRNA adaptors, the abundance of which can affect the decoding rate and translation efficiency. To determine whether cells alter tRNA abundance to selectively regulate protein expression, we quantified changes in the abundance of individual tRNAs at different time points in response to diverse stress conditions in Saccharomyces cerevisiae. [...]
2018 - 10.1126/scisignal.aat6409
Science Signaling, Vol. 11, Issue 546 (September 2018) , art. eaat6409
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6.
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14 p, 3.1 MB |
RNA-binding and prion domains : the Yin and Yang of phase separation
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Gotor, Nieves Lorenzo (Centre de Regulació Genòmica) ;
Armaos, Alexandros (Centre de Regulació Genòmica) ;
Calloni, Giulia (Goethe University Frankfurt) ;
Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Vabulas, R. Martin (Goethe University Frankfurt) ;
Sánchez de Groot, Natalia (Centre de Regulació Genòmica) ;
Tartaglia, Gian Gaetano (Centre de Regulació Genòmica)
Proteins and RNAs assemble in membrane-less organelles that organize intracellular spaces and regulate biochemical reactions. The ability of proteins and RNAs to form condensates is encoded in their sequences, yet it is unknown which domains drive the phase separation (PS) process and what are their specific roles. [...]
2020 - 10.1093/nar/gkaa681
Nucleic acids research, Vol. 48, Issue 17 (September 2020) , p. 9491-9504
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13 p, 5.2 MB |
Discovering putative prion-like proteins in Plasmodium falciparum : a computational and experimental analysis
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Pallarès i Goitiz, Irantzu (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Sánchez de Groot, Natalia (Centre de Regulació Genòmica) ;
Iglesias, Valentin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Sant'Anna, Ricardo (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Biosca, Arnau (Institut de Bioenginyeria de Catalunya) ;
Fernàndez-Busquets, Xavier (Institut de Bioenginyeria de Catalunya) ;
Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Prions are a singular subset of proteins able to switch between a soluble conformation and a self-perpetuating amyloid state. Traditionally associated with neurodegenerative diseases, increasing evidence indicates that organisms exploit prion-like mechanisms for beneficial purposes. [...]
2018 - 10.3389/fmicb.2018.01737
Frontiers in microbiology, Vol. 9 (Aug. 2018) , art. 1737
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