Home > Search Results: de Rooij, Dirk G.
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Results overview: Found 3 records in 0.02 seconds.
Articles, 3 records found
Articles 3 records found  
1.
12 p, 7.0 MB ATR is a multifunctional regulator of male mouse meiosis / Widger, Alexander (The Francis Crick Institute) ; Mahadevaiah, Shantha K. (Francis Crick Institute) ; Lange, Julian (Memorial Sloan Kettering Cancer Center) ; Elinati, Elias (The Francis Crick Institute) ; Zohren, Jasmin (The Francis Crick Institute) ; Hirota, Takayuki (The Francis Crick Institute) ; Pacheco, Sarai (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Maldonado Linares, Andros (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Stanzione, Marcello (TU Dresden. Faculty of Medicine) ; Ojarikre, Obah (The Francis Crick Institute) ; Maciulyte, Valdone (The Francis Crick Institute) ; De Rooij, Dirk G.. (University of Amsterdam. Center for Reproductive Medicine) ; Tóth, Attila (TU Dresden. Faculty of Medicine) ; Roig, Ignasi (Ignasi) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Keeney, Scott (Memorial Sloan Kettering Cancer Center) ; Turner, James M. A. (Francis Crick Institute)
Meiotic cells undergo genetic exchange between homologs through programmed DNA double-strand break (DSB) formation, recombination and synapsis. In mice, the DNA damage-regulated phosphatidylinositol-3-kinase-like kinase (PIKK) ATM regulates all of these processes. [...]
2018 - 10.1038/s41467-018-04850-0
Nature communications, Vol. 9 (2018) , art. 2621  
Detailed record - Creative Commons
2.
31 p, 4.4 MB The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility / Gomez Hernández, Laura (Centro de Investigación del Cáncer) ; Felipe Medina, Natalia (Centro de Investigación del Cáncer) ; Bejarano Condezo, Yazmine (Centro de Investigación del Cáncer) ; Garcia Valiente, Rodrigo (Centro de Investigación del Cáncer) ; Ramos, Isabel (Centro de Investigación del Cáncer) ; Suja, José Ángel (Universidad Autónoma de Madrid. Unidad de Biologia Celular) ; Barbero, José Luis (Centro de Investigaciones Biológicas (Madrid)) ; Roig, Ignasi (Ignasi) (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sanchez Martin, Manuel. (Universidad de Salamanca. Departamento de Medicina) ; De Rooij, Dirk G.. (Utrecht University. Departent of Biology) ; Llano, Elena (Universidad de Salamanca. Departamento de Fisiología y Farmacología) ; Martín Pendas, Alberto (Centro de Investigación del Cáncer)
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [...]
2019 - 10.1371/journal.pgen.1008316
PLoS Genetics, Vol. 15, issue 8 (August 2019) , e1008316  
Detailed record - Creative Commons
3.
17 p, 866.2 KB ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes / Barchi, Marco (Memorial Sloan Kettering Cancer Center) ; Roig, Ignasi, (Ignasi) dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Di Giacomo, Monica (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ; De Rooij, Dirk G.. (Utrecht University. Department of Endocrinology and Metabolism (Països Baixos)) ; Keeney, Scott (Cornell University. Weill Graduate School of Medical Sciences (Nova York, Estats Units d'Amèrica)) ; Jasin, Maria (Cornell University. Weill Graduate School of Medical Sciences (Nova York, Estats Units d'Amèrica))
During meiosis in most sexually reproducing organisms, recombination forms crossovers between homologous maternal and paternal chromosomes and thereby promotes proper chromosome segregation at the first meiotic division. [...]
2008 - 10.1371/journal.pgen.1000076
PLoS Genetics, Vol. 4, Issue 5 (May 2008) , p. e1000076  
Detailed record - Creative Commons

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