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1.
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22 p, 3.7 MB |
Comparative Analysis of PSA Density and an MRI-Based Predictive Model to Improve the Selection of Candidates for Prostate Biopsy
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Morote Robles, Juan (Hospital Universitari Vall d'Hebron) ;
Borque-Fernando, Ángel (Hospital Universitario Miguel Servet (Saragossa)) ;
Triquell, Marina (Hospital Universitari Vall d'Hebron) ;
Celma, Ana (Hospital Universitari Vall d'Hebron) ;
Regis, Lucas (Hospital Universitari Vall d'Hebron) ;
Mast, Richard (Hospital Universitari Vall d'Hebron) ;
de Torres, Inés M. (Hospital Universitari Vall d'Hebron) ;
Semidey, María E. (Hospital Universitari Vall d'Hebron) ;
Abascal, Jose Maria (Parc de Salut MAR de Barcelona) ;
Servian, Pol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fàbrega-Santamaria, Anna (Hospital Universitari Vall d'Hebron) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron) ;
Esteban, Luis M (Universidad de Zaragoza) ;
Trilla Herrera, Enrique (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Magnetic resonance imaging (MRI)-associated prostate-specific antigen density (mPSAD) and MRI predictive models have been proposed for improving the selection of candidates for prostate biopsy among men with suspected prostate cancer (PCa). [...]
2022 -  10.3390/cancers14102374
Cancers, Vol. 14 (may 2022)
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2.
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22 p, 4.7 MB |
Loss of microRNA-135b Enhances Bone Metastasis in Prostate Cancer and Predicts Aggressiveness in Human Prostate Samples
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Olivan, M (Hospital Universitari Vall d'Hebron) ;
García, Marta (Institut de Recerca Sant Joan de Déu) ;
Suárez, Leticia (Hospital Universitari Vall d'Hebron) ;
Guiu, Marc (Institut de Recerca Biomèdica) ;
Gros, Laura (Hospital Universitari Vall d'Hebron) ;
Méndez Fernández, Olga (Hospital Universitari Vall d'Hebron) ;
Rigau, Marina (Hospital Universitari de Bellvitge) ;
Reventós, Jaume (Hospital Universitari de Bellvitge) ;
Segura, Miguel F. (Hospital Universitari Vall d'Hebron) ;
de Torres, Inés (Hospital Universitari Vall d'Hebron) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron) ;
de la Cruz, Xavier (Hospital Universitari Vall d'Hebron) ;
Gomis, Roger R. (Hospital Universitari de Bellvitge) ;
Morote Robles, Juan (Hospital Universitari Vall d'Hebron) ;
Rodríguez-Barrueco, Ruth (Hospital Universitari de Bellvitge) ;
Santamaría, Anna (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Prostate cancer (PCa) is the most prevalent cancer in males worldwide, and it was the fifth leading cause of cancer mortality in this group in 2020. Near 70% of advanced-stage PCa patients will undergo bone metastasis, suffering pathological complications that severely affect patients' quality of life and probably progress in most cases to lethal PCa. [...]
2021 - 10.3390/cancers13246202
Cancers, Vol. 13 (december 2021)
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3.
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17 p, 2.5 MB |
Acute Stress Regulates Sex-Related Molecular Responses in the Human Jejunal Mucosa : Implications for Irritable Bowel Syndrome
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Rodiño-Janeiro, Bruno K. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pigrau Pastor, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Salvo-Romero, Eloísa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Nieto Ruiz, Adoración (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Expósito, Elba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
González Castro, Ana Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Galan Soldevilla, Carmen (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Torres, Inés (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Pribic, Teodora (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lobo Álvarez, Beatriz (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Fortea, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gallart, Milagros (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pardo-Camacho, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Guagnozzi, Danila (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Santos, Javier (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Alonso Cotoner, Carmen (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Universitat Autònoma de Barcelona
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder linked to intestinal barrier dysfunction and life stress. We have previously reported that female sex per se determines an increased susceptibility to intestinal barrier dysfunction after cold pain stress (CPS). [...]
2023 - 10.3390/cells12030423
Cells, Vol. 12 (january 2023)
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4.
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13 p, 1.7 MB |
The Barcelona Predictive Model of Clinically Significant Prostate Cancer
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Morote Robles, Juan (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Borque-Fernando, Ángel (Hospital Universitario Miguel Servet (Saragossa)) ;
Triquell, Marina (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Celma, Ana (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Regis, Lucas (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Escobar, Manel (Hospital Universitari Vall d'Hebron) ;
Mast, Richard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Torres, Inés (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Semidey, María E. (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Abascal, Jose Maria (Parc de Salut MAR de Barcelona) ;
Solà Belda, Carles (Parc de Salut MAR de Barcelona) ;
Servian, Pol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Salvador Hidalgo, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santamaría, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron) ;
Esteban, Luis M. (Universidad de Zaragoza. Departamento de Matemática Aplicada) ;
Trilla Herrera, Enrique (Universitat Autònoma de Barcelona. Departament de Cirurgia)
Magnetic-resonance-imaging-based predictive models (MRI-PMs) improve the MRI prediction of clinically significant prostate cancer (csPCa) in prostate biopsies. Risk calculators (RC) provide easy individual assessment of csPCa likelihood. [...]
2022 - 10.3390/cancers14061589
Cancers, Vol. 14 (march 2022)
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5.
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10 p, 1.3 MB |
Application of One-Step Nucleic Acid Amplification (OSNA) in different cancer entities and usefulness in prostate cancer : a systematic review
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Cuadras, Mercè (Hospital Universitari Vall d'Hebron) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron) ;
Celma, Ana (Hospital Universitari Vall d'Hebron) ;
Regis, Lucas (Hospital Universitari Vall d'Hebron) ;
de Torres, Inés (Hospital Universitari Vall d'Hebron) ;
Semidey, M. Eugenia (Hospital Universitari Vall d'Hebron) ;
Trilla, Enrique (Hospital Universitari Vall d'Hebron) ;
Morote Robles, Juan (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Universitat Autònoma de Barcelona
Lymph node (LN) status is a key prognostic factor in the decision-making process of different cancer entities, including prostate cancer (PCa). Sectioning and haematoxylin and eosin (H&E) staining technique remain the gold standard for the evaluation of LN metastases despite some limitations, especially low sensitivity in detecting an accurate tumour burden within the LN, as well as a subjective and time-consuming result. [...]
2022 - 10.1186/s12885-022-09355-0
BMC Cancer, Vol. 22 (april 2022)
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6.
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10 p, 555.0 KB |
The Efficacy of Proclarix to Select Appropriate Candidates for Magnetic Resonance Imaging and Derived Prostate Biopsies in Men with Suspected Prostate Cancer
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Morote Robles, Juan (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Campistol, Miriam (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Celma, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Regis, Lucas (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Torres, Inés (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Semidey, María E. (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Roche, Sarai (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mast, Richard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Santamaría, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Trilla Herrera, Enrique (Universitat Autònoma de Barcelona. Departament de Cirurgia)
To analyze how Proclarix is valuable to appropriately select candidates for multiparametric magnetic resonance imaging (mpMRI) and derived biopsies, among men with suspected prostate cancer (PCa). Proclarix is a new marker computing the clinically significant PCa (csPCa) risk, based on serum thosmbospondin-1, cathepsin D, prostate-specific antigen (PSA) and percent free PSA, in addition to age, that has been developed in men with serum PSA 2 to 10 ng/mL, prostate volume ≥35 mL, and normal digital rectal examination (DRE). [...]
2021 - 10.5534/wjmh.210117
The world journal of men's health, Vol. 40 (december 2021) , p. 270-279
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7.
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9 p, 604.9 KB |
Multiparametric Magnetic Resonance Imaging Grades the Aggressiveness of Prostate Cancer
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Morote Robles, Juan (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Borque-Fernando, Ángel (Hospital Universitario Miguel Servet (Saragossa)) ;
Triquell, Marina (Hospital Universitari Vall d'Hebron) ;
Celma, Ana (Hospital Universitari Vall d'Hebron) ;
Regis, Lucas (Hospital Universitari Vall d'Hebron) ;
Mast, Richard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Torres, Inés (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Semidey, María E. (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ;
Santamaría, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron) ;
Esteban, Luis M. (Universidad de Zaragoza) ;
Trilla Herrera, Enrique (Universitat Autònoma de Barcelona. Departament de Cirurgia)
Prostate cancer (PCa) aggressiveness can be assessed from clinical and pathologic surrogate endpoints as the International Society of Uropathology grade group (GG) in prostate biopsies, the type of pathology from surgical specimens, the clinical stage, and the risk of biochemical recurrence after treatment of localised PCa. [...]
2022 - 10.3390/cancers14071828
Cancers, Vol. 14 (april 2022)
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8.
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7 p, 828.4 KB |
Improving the Early Detection of Clinically Significant Prostate Cancer in Men in the Challenging Prostate Imaging-Reporting and Data System 3 Category
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Morote Robles, Juan (Hospital Universitari Vall d'Hebron) ;
Campistol, Miriam (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Triquell, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Celma, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Regis, Lucas (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Torres, Inés (Universitat Autònoma de Barcelona) ;
Semidey, Maria E. (Hospital Universitari Vall d'Hebron) ;
Mast, Richard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Santamaría, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Planas, Jacques (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Trilla Herrera, Enrique (Universitat Autònoma de Barcelona)
The efficacy of tools for selection of candidates for prostate biopsy after multiparametric magnetic resonance imaging (MRI) varies across Prostate Imaging-Reporting and Data System (PI-RADS) categories. [...]
2022 - 10.1016/j.euros.2021.12.009
European Urology Open Science, Vol. 37 (january 2022) , p. 38-44
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9.
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16 p, 1.3 MB |
Molecular Markers for Prostate Cancer in Formalin-Fixed Paraffin-Embedded Tissues
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Sequeiros, Tamara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montes, Melania (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Olivan, M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rigau, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Torres, Inés (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Morote Robles, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Reventós Puigjaner, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Doll, Andreas (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Prostate cancer (PCa) is the most frequently diagnosed type of cancer in developed countries. The decisive method of diagnosis is based on the results of biopsies, morphologically evaluated to determine the presence or absence of cancer. [...]
2013 - 10.1155/2013/283635
BioMed Research International, Vol. 2013 (november 2013)
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10.
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12 p, 11.3 MB |
Diabetes Protects from Prostate Cancer by Downregulating Androgen Receptor : New Insights from LNCaP Cells and PAC120 Mouse Model
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Barbosa-Desongles, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de Torres, Inés (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Munell Casadesus, Francina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poupon, Marie-France (Institut Curie) ;
Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martínez Selva, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Type 2 diabetes has been associated with decreased risk of prostate cancer in observational studies, and this inverse association has been recently confirmed in several large cohort studies. However the mechanisms involved in this protective effect remain to be elucidated. [...]
2013 - 10.1371/journal.pone.0074179
PloS one, Vol. 8 (september 2013)
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