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An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
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Blein, Sophie (Université Lyon 1) ;
Bardel, Claire (Université Claude Bernard Lyon 1) ;
Danjean, Vincent (INRIA Rhône-Alpes (França)) ;
McGuffog, Lesley (University of Cambridge) ;
Healey, Sue (QIMR Berghofer (Australia)) ;
Barrowdale, Daniel (University of Cambridge) ;
Lee, Andrew (University of Cambridge) ;
Dennis, Joe (University of Cambridge) ;
Kuchenbaecker, Karoline B (University of Cambridge) ;
Soucy, Penny (Laval University (Canadà)) ;
Terry, Mary Beth (Columbia University) ;
Chung, Wendy K (Columbia University College of Physicians and Surgeons) ;
Goldgar, David E (University of Utah School of Medicine) ;
Buys, Saundra S (University of Utah School of Medicine) ;
Janavicius, Ramunas (State Research Institute (Lituania)) ;
Tihomirova, Laima (Latvian Biomedical Research and Study Centre) ;
Tung, Nadine (Beth Israel Deaconess Medical Center (Estats Units d'Amèrica)) ;
Dorfling, Cecilia M (University of Pretoria) ;
van Rensburg, Elizabeth J (University of Pretoria (Estats Units d'Amèrica)) ;
Neuhausen, Susan L (Beckman Research Institute (Estats Units d'Amèrica)) ;
Ding, Yuan Chun (Beckman Research Institute (Estats Units d'Amèrica)) ;
Gerdes, Anne-Marie (Copenhagen University Hospital) ;
Ejlertsen, Bent (Copenhagen University Hospital) ;
Nielsen, Finn C (Copenhagen University Hospital) ;
Hansen, Thomas VO (Copenhagen University Hospital) ;
Osorio, Ana (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Benitez, Javier (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Conejero, Raquel Andrés (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Segota, Ena (Clinical Cancer Genetics Community Research Network(Estats Units d'Amèrica)) ;
Weitzel, Jeffrey N (Division of Clinical Cancer Genetics(Estats Units d'Amèrica)) ;
Thelander, Margo (Walnut Creek (Estats Units d'Amèrica)) ;
Peterlongo, Paolo (Istituto FIRC di Oncologia Molecolare) ;
Radice, Paolo (Istituto di Ricovero e Cura a Carattere Scientifico) ;
Pensotti, Valeria (Cogentech Cancer Genetic Test Laboratory (Itàlia)) ;
Dolcetti, Riccardo (Centro di Riferimento Oncologico (Itàlia)) ;
Bonanni, Bernardo (Istituto Europeo di Oncologia (Itàlia)) ;
Peissel, Bernard (Istituto di Ricovero e Cura a Carattere Scientifico (Itàlia)) ;
Zaffaroni, Daniela (Istituto di Ricovero e Cura a Carattere Scientifico (Itàlia)) ;
Scuvera, Giulietta (Istituto di Ricovero e Cura a Carattere Scientifico (Itàlia)) ;
Manoukian, Siranoush (Istituto di Ricovero e Cura a Carattere Scientifico (Itàlia)) ;
Varesco, Liliana (Istituto di Ricovero e Cura a Carattere Scientifico (Itàlia)) ;
Capone, Gabriele L (University of Florence, Florence) ;
Papi, Laura (University of Florence, Florence) ;
Ottini, Laura (Sapienza University) ;
Yannoukakos, Drakoulis (Aristotle University of Thessaloniki School of Medicine) ;
Konstantopoulou, Irene (Aghia Paraskevi Attikis) ;
Garber, Judy (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Hamann, Ute (Deutsches Krebsforschungszentrum) ;
Donaldson, Alan (St Michael's Hospital) ;
Brady, Angela (Kennedy-Galton Centre) ;
Brewer, Carole (Royal Devon & Exeter Hospital (Exeter, Regne Unit)) ;
Foo, Claire (Liverpool Women's NHS Foundation Trust) ;
Evans, D Gareth (Central Manchester University Hospitals NHS Foundation Trust) ;
Frost, Debra (University of Cambridge, Worts Causeway) ;
Eccles, Diana (Faculty of Medicine, University of Southampton, Southampton University Hospitals NHS Trust, Mailpoint 801, South Academic Block, PAH/G/MP105, Tremona Road, Southampton, SO16 6YD UK) ;
Douglas, Fiona (Institute of Human Genetics, Northern Genetic Service (Regne Unit)) ;
Cook, Jackie (Sheffield Children's Hospital (Sheffield, Regne Unit)) ;
Adlard, Julian (Yorkshire Regional Genetics Service) ;
Barwell, Julian (Leicestershire Clinical Genetics Service) ;
Walker, Lisa (Churchill Hospital) ;
Izatt, Louise (St Thomas' NHS Foundation Trust) ;
Side, Lucy E (Great Ormond Street Hospital for Children (Londres)) ;
Kennedy, M John (St. James's Hospital ( Dublín, Irlanda)) ;
Tischkowitz, Marc (Addenbrookes Hospital (Cambridge, Regne Unit)) ;
Rogers, Mark T (University Hospital of Wales) ;
Porteous, Mary E (Western General Hospital) ;
Morrison, Patrick J (Belfast City Hospital, Lisburn Road) ;
Platte, Radka (University of Cambridge) ;
Eeles, Ros (The Institute of Cancer Research and Royal Marsden NHS Foundation Trust) ;
Davidson, Rosemarie (Yorkhill Hospitals) ;
Hodgson, Shirley (St George's University of London) ;
Cole, Trevor (Birmingham Women's Hospital Healthcare NHS Trust) ;
Godwin, Andrew K (DUniversity of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160 USA) ;
Isaacs, Claudine (Lombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, 3800 Reservoir Road NW, Washington, DC 20057 USA) ;
Claes, Kathleen (Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium) ;
De Leeneer, Kim (Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium) ;
Meindl, Alfons (Division of Tumor Genetics, Department of Gynaecology and Obstetrics, University Hospital Klinikum Rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675 Munich, Germany) ;
Gehrig, Andrea (Center of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institut für Humangenetik, Biozentrum, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany) ;
Wappenschmidt, Barbara (Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Strasse 21, 50931 Cologne, Germany) ;
Sutter, Christian (Heidelberg University Hospital (Alemanya)) ;
Engel, Christoph (Institute for Medical Informatics, Statistics and Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany) ;
Niederacher, Dieter (University Hospital of Düsseldorf (Alemanya)) ;
Steinemann, Doris (Institute of Cell and Molecular Pathology, Centre for Pathology and Forensic and Genetic Medicine, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany) ;
Plendl, Hansjoerg (Institute of Human Genetics, University Medical Center Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 3, D-24105 Kiel, Germany) ;
Kast, Karin (Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus of Dresden, Technical University Dresden, Dresden, Germany) ;
Rhiem, Kerstin (Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Strasse 21, 50931 Cologne, Germany) ;
Ditsch, Nina (Division of Tumor Genetics, Department of Gynaecology and Obstetrics, University Hospital Klinikum Rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675 Munich, Germany) ;
Arnold, Norbert (Department of Gynecology and Obstetrics, University Medical Center Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 3, D-24105 Kiel, Germany) ;
Varon-Mateeva, Raymonda (Institute of Medical Genetics and Human Genetics, Campus Virchow-Klinikum, Charité Berlin - Universtitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany) ;
Schmutzler, Rita K (German Consortium of Hereditary Breast and Ovarian Cancer (GC-HBOC), Cologne, Germany) ;
Preisler-Adams, Sabine (University Hospital of Münster (Alemanya)) ;
Markov, Nadja Bogdanova (University Hospital of Münster (Alemanya)) ;
Wang-Gohrke, Shan (University Hospital of Ulm (Alemanya)) ;
o (Department of Tumour Biology, Institut Curie, 26 rue d'Ulm 75248, Paris, cedex 05 France) ;
Lefol, Cédrick (Department of Tumour Biology, Institut Curie, 26 rue d'Ulm 75248, Paris, cedex 05 France) ;
Lasset, Christine (Unité de Prévention et d'Épidémiologie Génétique, Centre Léon Bérard, 28 rue Laenned, 69008 Lyon, France) ;
Leroux, Dominique (Institut Albert Bonniot - Inserm U823, Université Joseph Fourier, Rond-point de la Chantourne, 38706 La Tronche, France) ;
Rouleau, Etienne (Laboratoire d'Oncogénétique, Hôpital René Huguenin, Institut Curie, 35 rue Dailly, 92210 Saint-Cloud, France) ;
Damiola, Francesca (Centre National de la Recherche Scientifique (França)) ;
Dreyfus, Hélène (Institut Albert Bonniot - Inserm U823, Université Joseph Fourier, Rond-point de la Chantourne, 38706 La Tronche, France) ;
Barjhoux, Laure (Centre National de la Recherche Scientifique (França)) ;
Golmard, Lisa (Department of Tumour Biology, Institut Curie, 26 rue d'Ulm 75248, Paris, cedex 05 France) ;
Uhrhammer, Nancy (Département d'Oncogénétique, Centre Jean Perrin, Université de Clermont-Ferrand, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France) ;
Bonadona, Valérie (Unité de Prévention et d'Épidémiologie Génétique, Centre Léon Bérard, 28 rue Laenned, 69008 Lyon, France) ;
Sornin, Valérie (Centre National de la Recherche Scientifique (França)) ;
Bignon, Yves-Jean (Département d'Oncogénétique, Centre Jean Perrin, Université de Clermont-Ferrand, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France) ;
Carter, Jonathan (Gynaecological Oncology, Sydney Cancer Centre, Royal Prince Alfred Hospital and University of Sydney, Missenden Road, Camperdown, NSW 2050 Australia) ;
Van Le, Linda (Gynecologic Oncology Group, Department of OB-GYN, University of North Carolina at Chapel Hill, 103B Physicians' Office Building, CB# 7572, Chapel Hill, NC 27599-7572 USA) ;
Piedmonte, Marion (Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263-0001 USA) ;
DiSilvestro, Paul A (Women & Infants Hospital, 1 Blackstone Place, Providence, RI 02905 USA) ;
de la Hoya, Miguel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Nevanlinna, Heli (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Biomedicum Helsinki, PO Box 700, 00029 Helsinki, Finland) ;
Aittomäki, Kristiina (Department of Clinical Genetics, Helsinki University Central Hospital, Biomedicum Helsinki 1, Haartmaninkatu 8, 00290 Helsinki, Finland) ;
Jager, Agnes (Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam, the Netherlands) ;
van den Ouweland, Ans MW (Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, the Netherlands) ;
Kets, Carolien M (Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands) ;
Aalfs, Cora M (Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands) ;
van Leeuwen, Flora E (Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands) ;
Hogervorst, Frans BL (Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, the Netherlands) ;
Meijers-Heijboer, Hanne EJ (Department of Clinical Genetics, VU University Medical Center Amsterdam, De Boelelaan 1118, 1081 HV Amsterdam, the Netherlands) ;
Oosterwijk, Jan C (Department of Genetics, University Medical Center, Groningen University, Groningen, the Netherlands) ;
van Roozendaal, Kees EP (Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands) ;
Rookus, Matti A (Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands) ;
Devilee, Peter (Department of Pathology, Leiden University Medical Center, PO Box 9600, 2300 RC L1Q Leiden, the Netherlands) ;
van der Luijt, Rob B (Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands) ;
Olah, Edith (Department of Molecular Genetics, National Institute of Oncology, Ráth György u 7-9, PO Box 1525 Budapest PF 21, 1122 Budapest, Hungary) ;
Diez, Orland (Vall d'Hebron Institut d'Oncologia) ;
Teulé, Alex (Institut d'Investigació Biomèdica de Bellvitge) ;
Lazaro, Conxi (Institut d'Investigació Biomèdica de Bellvitge) ;
Blanco, Ignacio (Institut d'Investigació Biomèdica de Bellvitge) ;
Del Valle, Jesús (Institut d'Investigació Biomèdica de Bellvitge) ;
Jakubowska, Anna (Department of Genetics and Pathomorphology, Faculty of Medicine and Dentistry, Pomeranian Medical University, al Powstancow Wlkp 72, 70-111 Szczecin, Poland) ;
Sukiennicki, Grzegorz (Department of Genetics and Pathomorphology, Faculty of Medicine and Dentistry, Pomeranian Medical University, al Powstancow Wlkp 72, 70-111 Szczecin, Poland) ;
Gronwald, Jacek (Department of Genetics and Pathomorphology, Faculty of Medicine and Dentistry, Pomeranian Medical University, al Powstancow Wlkp 72, 70-111 Szczecin, Poland) ;
Lubinski, Jan (Department of Genetics and Pathomorphology, Faculty of Medicine and Dentistry, Pomeranian Medical University, al Powstancow Wlkp 72, 70-111 Szczecin, Poland) ;
Durda, Katarzyna (Department of Genetics and Pathomorphology, Faculty of Medicine and Dentistry, Pomeranian Medical University, al Powstancow Wlkp 72, 70-111 Szczecin, Poland) ;
Jaworska-Bieniek, Katarzyna (Department of Genetics and Pathomorphology, Faculty of Medicine and Dentistry, Pomeranian Medical University, al Powstancow Wlkp 72, 70-111 Szczecin, Poland) ;
Agnarsson, Bjarni A (Landspítali National University Hospital of Iceland and Faculty of Medicine, School of Health Sciences, University of Iceland School of Medicine, Sæmundargötu 2, 101 Reykjavik, Iceland) ;
Maugard, Christine (Laboratoire de diagnostic génétique et Service d'Onco-hématologie, Les Hopitaux Universitaire de Strasbourg, Nouvel Hôpital Civil, 1 place de l'Hôpital, BP 426, 67091 Strasbourg, France) ;
Amadori, Alberto (Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV) - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), via Gattamelata 64, 35128 Padua, Italy) ;
Montagna, Marco (Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV) - Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), via Gattamelata 64, 35128 Padua, Italy) ;
Teixeira, Manuel R (Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal) ;
Spurdle, Amanda B (Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia) ;
Foulkes, William (Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, 546 Pine Avenue West, Montreal, QC J2W 1S6 Canada) ;
Olswold, Curtis (Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905 USA) ;
Lindor, Noralane M (Department of Health Sciences Research, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259 USA) ;
Pankratz, Vernon S (Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905 USA) ;
Szabo, Csilla I (National Human Genome Research Institute, National Institutes of Health, Building 31, Room 4B09, 31 Center Drive, MSC 2152, 9000 Rockville Pike, Bethesda, MD 20892-2152 USA) ;
Lincoln, Anne (Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA) ;
Jacobs, Lauren (Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA) ;
Corines, Marina (Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA) ;
Robson, Mark (Clinical Genetics Research Laboratory, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA) ;
Vijai, Joseph (Clinical Genetics Research Laboratory, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA) ;
Berger, Andreas (Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Universitätsklinik für Frauenheilkunde, AKH - Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria) ;
Fink-Retter, Anneliese (Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Universitätsklinik für Frauenheilkunde, AKH - Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria) ;
Singer, Christian F (Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Universitätsklinik für Frauenheilkunde, AKH - Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria) ;
Rappaport, Christine (Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Universitätsklinik für Frauenheilkunde, AKH - Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria) ;
Kaulich, Daphne Geschwantler (Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Universitätsklinik für Frauenheilkunde, AKH - Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria) ;
Pfeiler, Georg (Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Universitätsklinik für Frauenheilkunde, AKH - Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria) ;
Tea, Muy-Kheng (Department of Obstetrics and Gynecology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Universitätsklinik für Frauenheilkunde, AKH - Wien, Währinger Gürtel 18-20, 1090 Vienna, Austria) ;
Greene, Mark H (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD USA) ;
Mai, Phuong L (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD USA) ;
Rennert, Gad (Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, 2 Horev Street, 34362 Haifa, Israel) ;
Imyanitov, Evgeny N (NN Petrov Institute of Oncology, 68 Leningradskaya Street, Pesochny, 197758 St Petersburg Russia) ;
Mulligan, Anna Marie (Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, 209 Victoria Street, Toronto, ON M5B 1T8 Canada) ;
Glendon, Gord (Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Joseph and Wolf Lebovic Health Complex, 600 University Avenue, Toronto, ON M5G 1X5 Canada) ;
Andrulis, Irene L (Department of Molecular Genetics, University of Toronto, Medical Science Building, Room 4386, 1 King's College Circle, Toronto, ON M5S 1A8 Canada) ;
Tchatchou, Sandrine (Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital Joseph and Wolf Lebovic Health Complex, 600 University Avenue, Toronto, ON M5G 1X5 Canada) ;
Toland, Amanda Ewart (The Ohio State University Comprehensive Cancer Center - Arthur G James Cancer Hospital and Richard J Solove Research Institute (OSUCCC - James), 460 West 10th Avenue, Columbus, OH 43210 USA) ;
Pedersen, Inge Sokilde (Aalborg University Hospital (Dinamarca)) ;
Thomassen, Mads (Odense University Hospital (Dinamarca)) ;
Kruse, Torben A (Odense University Hospital (Dinamarca)) ;
Jensen, Uffe Birk (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Caligo, Maria A (Laboratorio di Genetica Oncologica, Divisione di Anatomia Patologica e di Diagnostica Molecolare ed Ultrastrutturale, Azienda Ospedaliero Universitaria Pisana - Ospedale S Chiara, via Roma 67, 56126 Pisa, Italy) ;
Friedman, Eitan (Sheba Laboratory of Molecular Genetics, The Danek Gertner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer, Ramat Gan, 52621 Tel Aviv, Israel) ;
Zidan, Jamal (Institute of Oncology, Rivka Ziv Medical Center, Maimonides, 13100 Safed, Israel) ;
Laitman, Yael (Sheba Laboratory of Molecular Genetics, The Danek Gertner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer, Ramat Gan, 52621 Tel Aviv, Israel) ;
Lindblom, Annika (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Melin, Beatrice (Oncology, Department of Radiation Sciences, Umeå University, SE-901 87 Umeå, Sweden) ;
Arver, Brita (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Loman, Niklas (Division of Oncology and Pathology, Department of Clinical Sciences, Lund University Hospital, Barngatan 2B, SE-221 85 Lund, Sweden) ;
Rosenquist, Richard (Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden) ;
Olopade, Olufunmilayo I (Center for Clinical Cancer Genetics and Global Health, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637 USA) ;
Nussbaum, Robert L (Department of Medicine and Genetics, University of California, San Francisco, CA USA) ;
Ramus, Susan J (Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Norris Comprehensive Cancer Center, NOR-4435, Los Angeles, CA 90089-9175 USA) ;
Nathanson, Katherine L (Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Suite 750, Philadelphia, PA 19104-3309 USA) ;
Domchek, Susan M (Department of Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Suite 750, Philadelphia, PA 19104-3309 USA) ;
Rebbeck, Timothy R (Department of Epidemiology and Biostatistics, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Suite 750, Philadelphia, PA 19104-3309 USA) ;
Arun, Banu K (Division of Cancer Medicine, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Unit 1354, PO Box 301439, Houston, TX 77230-1439 USA) ;
Mitchell, Gillian (Sir Peter MacCallum Department of Oncology, The University of Melbourne, Level 5, 161 Barry Street, Parkville, 3010 VIC Australia) ;
Karlan, Beth Y (Women's Cancer Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048 USA) ;
Lester, Jenny (Women's Cancer Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048 USA) ;
Orsulic, Sandra (Women's Cancer Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048 USA) ;
Stoppa-Lyonnet, Dominique (Faculté de Médecine, Université Paris Descartes, Sorbonne Paris Cité, 15 rue de l'école de médecine, 75006 Paris, France) ;
Thomas, Gilles (Institut National du Cancer (INCa), La Fondation Synergie Lyon Cancer, Centre Léon Bérard, 28 rue Laënnec, 69008 Lyon, Cedex 08 France) ;
Simard, Jacques (Centre de recherche du Centre hospitalier universitaire de Québec, Laval University, Charlesbourg, PQ Canada) ;
Couch, Fergus J (Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905 USA) ;
Offit, Kenneth (Clinical Genetics Research Laboratory, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA) ;
Easton, Douglas F (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK) ;
Chenevix-Trench, Georgia (Department of Genetics and Computational Biology, QIMR Berghofer, Brisbane, Australia) ;
Antoniou, Antonis C (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK) ;
Mazoyer, Sylvie (Université Lyon 1, 69100 Villeurbanne, France) ;
Phelan, Catherine M (Department of Cancer Epidemiology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612 USA) ;
Sinilnikova, Olga M (Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon - Centre Léon Bérard, 69373 Lyon, Cedex 08 France) ;
Cox, David G (Université Lyon 1, 69100 Villeurbanne, France) ;
Universitat Autònoma de Barcelona
Individuals carrying pathogenic mutations in the BRCA1 and BRCA2 genes have a high lifetime risk of breast cancer. BRCA1 and BRCA2 are involved in DNA double-strand break repair, DNA alterations that can be caused by exposure to reactive oxygen species, a main source of which are mitochondria. [...]
2015 -  10.1186/s13058-015-0567-2
Breast cancer research, Vol. 17 (april 2015)
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