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11 p, 458.4 KB |
Pembrolizumab in Asian patients with microsatellite-instability-high/mismatch-repair-deficient colorectal cancer
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Yoshino, Takayuki (National Cancer Center Hospital East) ;
Andre, Thierry (Sorbonne University) ;
Kim, Tae Won (University of Ulsan) ;
Yong, Wei Peng (National University Cancer Institute) ;
Shiu, Kai-Keen (University College Hospital) ;
Jensen, Benny Vittrup (Herlev and Gentofte Hospital) ;
Jensen, Lars Henrik (University Hospital of Southern Denmark) ;
Punt, Cornelis J. A. (University Medical Center Utrecht) ;
Smith, Denis (Hôpital Haut-Lévêque) ;
García-Carbonero, Rocío (Imas12, Universidad Complutense de Madrid) ;
Alcaide-Garcia, Julia (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Gibbs, Peter (Western Hospital) ;
de la Fouchardiere, Christelle (Centre Léon Bérard) ;
Rivera, Fernando (Fernando Rivera, University Hospital Marqués de Valdecilla) ;
Elez, Elena (Vall d'Hebron Institut d'Oncologia) ;
Le, Dung T. (Johns Hopkins Medicine) ;
Adachi, Noriaki (Merck (Estats Units d'Amèrica)) ;
Fogelman, David (Merck(Estats Units d'Amèrica)) ;
Marinello, Patricia (Merck (Estats Units d'Amèrica)) ;
Diaz, Luis A. (Memorial Sloan Kettering Cancer Center) ;
Universitat Autònoma de Barcelona
The phase 3 KEYNOTE-177 study evaluated pembrolizumab versus chemotherapy with or without bevacizumab or cetuximab in patients with newly diagnosed, microsatellite-instability-high (MSI-H)/mismatch-repair-deficient (dMMR) metastatic colorectal cancer (mCRC). [...]
2022 -  10.1111/cas.15650
Cancer Science, Vol. 114 (december 2022) , p. 1026-1036
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9 p, 3.5 MB |
First fossil of Varanus Merrem (Squamata: Varanidae) from the Miocene Siwaliks of Pakistan
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Villa, Andrea (Institut Català de Paleontologia Miquel Crusafont) ;
Delfino, Massimo (Institut Català de Paleontologia Miquel Crusafont)
In the '50s of the XX century, a German expedition lead by Richard Dehm collected a large amount of fossil remains from northern Pakistan. Among these was an isolated trunk vertebra of a lizard, which is here referred to Varanus sp. [...]
Dans les années 50 du XXème siècle, une expédition allemande dirigée par Richard Dehm a recueilli une grande quantité de restes fossiles dans le nord du Pakistan. Parmi ceux-ci se trouvait une vertèbre isolée du tronc d'un lézard, qui est ici désigné comme Varanus sp. [...]
2022 - 10.5252/geodiversitas2022v44a7
Geodiversitas, Vol. 44, Issue 7 (February 2022) , p. 229-235
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The diversification of the lynx lineage during the Plio-Pleistocene-evidence from a new small Lynx from Longdan, Gansu Province, China
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Jianzuo, Qigao (Peking University. School of Earth and Space Sciences) ;
Li, Lu (Chinese Academy of Sciences.Institute of Vertebrate Paleontology and Paleoanthropology) ;
Madurell-Malapeira, Joan (Institut Català de Paleontologia Miquel Crusafont) ;
Wang, Shiqi (Chinese Academy of Sciences. Institute of Vertebrate Paleontology and Paleoanthropology) ;
Li, Shijie (Chinese Academy of Sciences. Institute of Vertebrate Paleontology and Paleoanthropology) ;
Fu, Jiao (Chinese Academy of Sciences. Institute of Vertebrate Paleontology and Paleoanthropology) ;
Chen, Shanqin (Hezheng Paleozoological Museum)
A new small-sized lynx from Longdan, Gansu Province, China, Lynx hei sp. nov. , is described in this study. The new species displays the characteristic Lynx generic traits, such as distinct buccal grooves in the upper canine, presence of an anterior groove in the upper canine, absence of upper premolar 2, and a moderately developed mastoid process, but it is markedly smaller than the previously described Lynx issiodorensis specimens from the same site and is also smaller overall than most living species, comparable to Lynx rufus in size. [...]
2022 - 10.1093/biolinnean/blac054
Biological Journal of the Linnean Society, Vol. 136, Issue 4 (August 2022) , p. 536-551
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56 p, 10.8 MB |
Cochlear morphology of Indonesian Homo erectus from Sangiran
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Urciuoli, Alessandro (Institut Català de Paleontologia Miquel Crusafont) ;
Kubat, Jülide (Centre National de la Recherche Scientifique. Université de Paris) ;
Schisanowski, Lisa (Senckenberg Research Institute and Natural History Museum Frankfurt. Division of Palaeoanthropology) ;
Schrenk, Friedemann (Senckenberg Research Institute and Natural History Museum Frankfurt. Division of Palaeoanthropology) ;
Zipfel, Bernhard (University of the Witwatersrand. Evolutionary Studies Institute (South Africa)) ;
Tawane, Mirriam (Ditsong National Museum of Natural History (South Africa)) ;
Bam, Lunga (South African Nuclear Energy Corporation. Department of Radiation Science) ;
Alba, David M.. (Institut Català de Paleontologia Miquel Crusafont) ;
Kullmer, Ottmar (Senckenberg Research Institute and Natural History Museum Frankfurt. Division of Palaeoanthropology)
Homo erectus s. l. is key for deciphering the origin and subsequent evolution of genus Homo. However, the characterization of this species is hindered by the existence of multiple variants in both mainland and insular Asia, as a result of divergent chronogeographical evolutionary trends, genetic isolation, and interbreeding with other human species. [...]
2022 - 10.1016/j.jhevol.2022.103163
Journal of human evolution, Vol. 165 (April 2022) , art. 103163
2 documents
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34 p, 821.8 KB |
Demographic change and increasing late singlehood in East Asia, 2010-2050
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Esteve, Albert (Centre d'Estudis Demogràfics) ;
Kashyap, Ridhi (University of Oxford) ;
Garcia Roman, Joan (Centre d'Estudis Demogràfics) ;
Cheng, Yen-hsin Alice (Academia Sinica (Taiwan)) ;
Fukuda, Setsuya ;
Nie, Wanli (Université catholique de Louvain) ;
Lee, Hyun-ok (Yonsei University (South Korea))
Background: Marriage is a central institution for social reproduction in East Asia. Until the 1970s and 1980s, marriage across much of East Asia was early and universal. In recent decades, though, this pattern has begun shifting to one of later and less marriage. [...]
2020 - 10.4054/DemRes.2020.43.46
Demographic research, Vol. 43 Núm. 46 (2020) , p. 1367-1398
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28 p, 356.8 KB |
Historiografía y arqueología greco-bactrianas : una breve guía
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Mendoza Sanahuja, Marc (Universitat Autònoma de Barcelona)
Este artículo busca ser una primera aproximación en castellano a la investigación sobre el helenismo en Asia Central e India. Dada la inexistencia de una tradición historiográfica de este campo en lengua castellana, el presente artículo resume los más de doscientos años de investigación hasta el momento con una voluntad divulgativa. [...]
The Greco-Bactrian kingdom is probably the most unknown of the main Hellenistic realms by the public and a significant part of the academic community. The contributions to this field by Spanish-speaking researchers has been anecdotal in comparison with other historiographical traditions. [...]
2020
Karanos, Vol. 3 (2020) , p. 131-156 (Articles)
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12 p, 3.9 MB |
Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage
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Hendriksen, Rene S. (National Food Institute. Technical University of Denmark) ;
Munk, Patrick (Technical University of Denmark. National Food Institute.) ;
Njage, Patrick (Technical University of Denmark. National Food Institute.) ;
van Bunnik, Bram (University of Edinburgh. Usher Institute.) ;
McNally, Luke (University of Edinburgh. Centre for Synthetic and Systems Biology. School of Biological Sciences.) ;
Lukjancenko, Oksana (Technical University of Denmark. National Food Institute.) ;
Röder, Timo (Technical University of Denmark. National Food Institute.) ;
Nieuwenhuijse, David (Erasmus Medical Center. Viroscience.) ;
Pedersen, Susanne Karlsmose (Technical University of Denmark. National Food Institute.) ;
Kjeldgaard, Jette (Technical University of Denmark. National Food Institute.) ;
Kaas, Rolf S. (Technical University of Denmark. National Food Institute.) ;
Clausen, Philip Thomas Lanken Conradsen (Technical University of Denmark. National Food Institute.) ;
Vogt, Josef Korbinian (Technical University of Denmark. National Food Institute.) ;
Leekitcharoenphon, Pimlapas (Technical University of Denmark. National Food Institute.) ;
van de Schans, Milou G. M. (RIKILT Wageningen University and Research) ;
Zuidema, Tina (RIKILT Wageningen University and Research) ;
de Roda Husman, Ana Maria (National Institute for Public Health and the Environment (RIVM)) ;
Rasmussen, Simon (Technical University of Denmark. Department of Bio and Health Informatics.) ;
Petersen, Bent (Technical University of Denmark. Department of Bio and Health Informatics.) ;
Bego, Artan (Institute of Public Health) ;
Rees, Charlotte (Melbourne Water Corporation) ;
Cassar, Susan (Melbourne Water Corporation) ;
Coventry, Kris (Melbourne Water Corporation) ;
Collignon, Peter (Canberra Hospital) ;
Allerberger, Franz (Austrian Agency for Health and Food Safety (AGES)) ;
Rahube, Teddie O. (Botswana International University of Science and Technology) ;
Oliveira, Guilherme (Vale Institute of Technology. Sustainable Development) ;
Ivanov, Ivan (National Center of Infectious and Parasitic Diseases) ;
Vuthy, Yith (Institut Pasteur du Cambodge) ;
Sopheak, Thet (Institut Pasteur du Cambodge) ;
Yost, Christopher K. (University of Regina) ;
Ke, Changwen (Guangdong Provincial Center for Disease Control and Prevention) ;
Zheng, Huanying (Guangdong Provincial Center for Disease Control and Prevention) ;
Baisheng, Li (Guangdong Provincial Center for Disease Control and Prevention) ;
Jiao, Xiaoyang (Shantou University Medical College) ;
Donado-Godoy, Pilar (Corporacion Colombiana de Investigacion Agropecuaria (AGROSAVIA)) ;
Coulibaly, Kalpy Julien (Institut Pasteur de Côte d'Ivoire) ;
Jergović, Matijana (Andrija Stampar Teaching Institute of Public Health) ;
Hrenovic, Jasna (University of Zagreb) ;
Karpíšková, Renáta (Veterinary Research Institute) ;
Villacis, Jose Eduardo (Instituto Nacional de Investigación en Salud Pública-INSPI (CRNRAM)) ;
Legesse, Mengistu (Addis Ababa University) ;
Eguale, Tadesse (Addis Ababa University) ;
Heikinheimo, Annamari (University of Helsinki) ;
Malania, Lile (National Center for Disease Control and Public Health) ;
Nitsche, Andreas (Robert Koch Institute) ;
Brinkmann, Annika (Robert Koch Institute) ;
Saba, Courage Kosi Setsoafia (University for Development Studies) ;
Kocsis, Bela (Semmelweis University. Institute of Medical Microbiology) ;
Solymosi, Norbert (University of Veterinary Medicine) ;
Thorsteinsdottir, Thorunn R. (University of Iceland. Institute for Experimental Pathology) ;
Hatha, Abdulla Mohamed (Cochin University of Science and Technology) ;
Alebouyeh, Masoud (Shahid Beheshti University of Medical Sciences. Foodborne and Waterborne Diseases Research center) ;
Morris, Dearbhaile (National University of Ireland Galway) ;
Cormican, Martin (National University of Ireland Galway) ;
O'Connor, Louise (National University of Ireland Galway) ;
Moran-Gilad, Jacob (Ben Gurion University of the Negev and Ministry of Health. School of Public Health) ;
Alba, Patricia (Istituto Zooprofilattico Sperimentale del Lazio e della Toscana) ;
Battisti, Antonio (Istituto Zooprofilattico Sperimentale del Lazio e della Toscana) ;
Shakenova, Zeinegul (National Center of Expertise) ;
Kiiyukia, Ciira (Mount Kenya University) ;
Ng'eno, Eric (Kenya Medical Research Institute) ;
Raka, Lul (University of Prishtina "Hasan Prishtina" & National Institute of Public Health of Kosovo) ;
Avsejenko, Jeļena (Institute of Food Safety) ;
Bērziņš, Aivars (Institute of Food Safety) ;
Bartkevics, Vadims (Institute of Food Safety) ;
Penny, Christian (Luxembourg Institute of Science and Technology) ;
Rajandas, Heraa (Environmental Health Directorate) ;
Parimannan, Sivachandran (AIMST University (Malàisia). Centre of Excellence for Omics-Driven Computational Biodiscovery) ;
Haber, Malcolm Vella (Agriculture and Forestry University) ;
Pal, Pushkar (University of Otago) ;
Jeunen, Gert-Jan (University of Ibadan) ;
Gemmell, Neil (University of Ibadan) ;
Fashae, Kayode (VEAS) ;
Holmstad, Rune (Aga Khan University) ;
Hasan, Rumina (National Institute of Health) ;
Shakoor, Sadia (National Institute of Health) ;
Rojas, Maria Luz Zamudio (National Veterinary Research Institute) ;
Wasyl, Dariusz (Institute of Public Health of the Republic of Macedonia) ;
Bosevska, Golubinka (State Medical and Pharmaceutical University) ;
Kochubovski, Mihail (State Medical and Pharmaceutical University) ;
Radu, Cojocaru (Institut Pasteur de Dakar) ;
Gassama, Amy (Institute of Veterinary Medicine of Serbia) ;
Radosavljevic, Vladimir (Nanyang Technological University. Singapore Centre for Environmental Life Sciences Engineering (SCELSE)) ;
Wuertz, Stefan (Nanyang Technological University Food Technology Centre (NAFTEC)) ;
Zuniga-Montanez, Rogelio (Nanyang Technological University Food Technology Centre (NAFTEC)) ;
Tay, Moon Y. F. (Public Health Authority of the Slovak Republic) ;
Gavačová, Dagmar (National Laboratory of Health. Environment and Food) ;
Pastuchova, Katarina (National Laboratory of Health. Environment and Food) ;
Truska, Peter (National Laboratory of Health. Environment and Food) ;
Trkov, Marija (Daspoort Waste Water Treatment Works) ;
Esterhuyse, Kerneels (University of the Witwatersrand) ;
Keddy, Karen (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Cerdà-Cuéllar, Marta (Medical Research Institute) ;
Pathirage, Sujatha (Swedish University of Agricultural Sciences) ;
Norrgren, Leif (The Sahlgrenska Academy at the University of Gothenburg) ;
Örn, Stefan (The Sahlgrenska Academy at the University of Gothenburg) ;
Larsson, D. G. Joakim (Ara Region Bern Ag) ;
Heijden, Tanja Van der (Kilimanjaro Clinical Research Institute) ;
Kumburu, Happiness Houka (National Public Health Laboratories) ;
Sanneh, Bakary (National Institute of Hygiene) ;
Bidjada, Pawou (Agence de Médecine Préventive) ;
Njanpop-Lafourcade, Berthe-Marie (Agence Médecine Préventive) ;
Nikiema-Pessinaba, Somtinda Christelle (Public Health Institution of Turkey) ;
Levent, Belkis (University of Washington) ;
Meschke, John Scott (Institute of Public Health in Ho Chi Minh City) ;
Beck, Nicola Koren (Institute of Public Health in Ho Chi Minh City) ;
Van, Chinh Dang (University of Zambia) ;
Phuc, Nguyen Do (University of Zambia) ;
Tran, Doan Minh Nguyen (University of Zambia) ;
Kwenda, Geoffrey (University of N'Djamena) ;
Tabo, Djim-adjim (Norwegian Institute of Public Health) ;
Wester, Astrid Louise (Universidad Católica del Maule) ;
Cuadros-Orellana, Sara (Universidad Católica del Maule. Centro de Biotecnología de los Recursos Naturales) ;
Amid, C. (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Cochrane, G. (European Molecular Biology Laboratory. European Bioinformatics Institute) ;
Sicheritz-Ponten, T. (AIMST University (Malàisia). Centre of Excellence for Omics-Driven Computational Biodiscovery) ;
Schmitt, H. (National Institute for Public Health and the Environment (RIVM)) ;
Alvarez, J. R. M. (World Health Organization) ;
Aidara-Kane, A. (World Health Organization) ;
Pamp, S. J. (Technical University of Denmark. National Food Institute.) ;
Lund, O. (Technical University of Denmark. Department of Bio and Health Informatics.) ;
Hald, T. (Technical University of Denmark. National Food Institute.) ;
Woolhouse, M. (University of Edinburgh. Usher Institute) ;
Koopmans, M. P. (Erasmus Medical Center. Viroscience) ;
Vigre, H. (Technical University of Denmark. National Food Institute.) ;
Petersen, T. N. (Technical University of Denmark. National Food Institute.) ;
Aarestrup, F. M. (Technical University of Denmark. National Food Institute.)
Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining representative data on AMR for healthy human populations is difficult. Here, we use metagenomic analysis of untreated sewage to characterize the bacterial resistome from 79 sites in 60 countries. [...]
2019 - 10.1038/s41467-019-08853-3
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 1124
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12 p, 2.8 MB |
Genome-wide patterns of homozygosity provide clues about the population history and adaptation of goats
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Bertolini, Francesca (Iowa State University. Department of Animal Science) ;
Cardoso, Tainã Figueiredo (Centre de Recerca en Agrigenòmica) ;
Marras, Gabriele (Fondazione Parco Tecnologico Padano) ;
Nicolazzi, Ezequiel L. (Fondazione Parco Tecnologico Padano (PTP)) ;
Rothschild, Max F. (Iowa State University. Department of Animal Science) ;
Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica)
Background: Patterns of homozygosity can be influenced by several factors, such as demography, recombination, and selection. Using the goat SNP50 BeadChip, we genotyped 3171 goats belonging to 117 populations with a worldwide distribution. [...]
2018 - 10.1186/s12711-018-0424-8
Genetics, selection, evolution, Vol. 50 (2018) , art. 59
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18 p, 591.2 KB |
Trajectòria artística del dibuixant Pere Ynglada (1881-1958) : de la Belle Époque a la síntesi oriental
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Bru Turull, Ricard (Universitat Autònoma de Barcelona. Departament d'Art i de Musicologia)
A partir de la dècada de 1920 Pere Ynglada va esdevenir un nom imprescindible i un referent del dibuix animalista a Catalunya. Aquest article indaga en la trajectòria vital d'Ynglada i posa èmfasi en les seves aportacions artístiques, des dels inicis en temps del modernisme i l'etapa de plenitud viscuda a París, fins als últims anys de la seva vida, de retorn a Barcelona.
From the 1920s onwards, the artist Pere Ynglada became a reference in Catalonia in the field of animal drawing. This article explores his vital trajectory and emphasizes Ynglada's artistic contributions from the beginnings of Catalan modernism and the stage of plenitude in Paris, to the last years of his life after returning to Barcelona.
A partir de la década de 1920 Pere Ynglada se convirtió en un nombre imprescindible y en un referente del dibujo animalista en Cataluña. Este artículo indaga en la trayectoria vital de Ynglada y pone énfasis en sus aportaciones artísticas, desde los inicios en tiempos del modernismo y la etapa de plenitud vivida en París, hasta los últimos años de su vida, de vuelta en Barcelona.
2019 - 10.5565/rev/locus.343
Locus amoenus, Vol. 17 (2019) , p. 151-167 (Articles)
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